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Cheap flights from South Carolina to La Crosse from $442

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to La Crosse departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:25 pm - 5:59 pm
CHS
-
LSE
6h 34m
1 stop
American Airlines Logo
9:48 am - 4:44 pm
LSE
-
CHS
5h 56m
1 stop
$457American Airlines
Thu, Mar 19 - Tue, Mar 24
American Airlines Logo
7:10 am - 11:01 am
CHS
-
LSE
4h 51m
1 stop
American Airlines Logo
5:09 am - 3:02 pm
LSE
-
CHS
8h 53m
2 stops
$463American Airlines
Thu, Mar 19 - Tue, Mar 24
American Airlines Logo
2:43 pm - 11:36 pm
CHS
-
LSE
9h 53m
2 stops
American Airlines Logo
9:48 am - 8:46 pm
LSE
-
CHS
9h 58m
2 stops
$468American Airlines
Thu, Mar 19 - Tue, Mar 24
American Airlines Logo
11:59 am - 5:59 pm
SAV
-
LSE
7h 00m
1 stop
American Airlines Logo
9:48 am - 9:23 pm
LSE
-
SAV
10h 35m
2 stops
$506American Airlines
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
2:55 pm - 11:36 pm
SAV
-
LSE
9h 41m
2 stops
American Airlines Logo
11:34 am - 9:44 pm
LSE
-
SAV
9h 10m
2 stops
$511American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
11:59 am - 5:59 pm
SAV
-
LSE
7h 00m
1 stop
American Airlines Logo
9:48 am - 4:30 pm
LSE
-
SAV
5h 42m
1 stop
$530American Airlines
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
11:59 am - 5:59 pm
SAV
-
LSE
7h 00m
1 stop
American Airlines Logo
9:48 am - 9:23 pm
LSE
-
SAV
10h 35m
2 stops
$533American Airlines
Thu, Mar 12 - Tue, Mar 24
American Airlines Logo
5:20 pm - 11:36 pm
SAV
-
LSE
7h 16m
1 stop
American Airlines Logo
11:34 am - 9:44 pm
LSE
-
SAV
9h 10m
2 stops
$536American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
11:59 am - 5:59 pm
SAV
-
LSE
7h 00m
1 stop
American Airlines Logo
9:48 am - 4:30 pm
LSE
-
SAV
5h 42m
1 stop
$557American Airlines
Thu, Mar 12 - Tue, Mar 24
United Airlines Logo
11:31 am - 12:15 am
CHS
-
LSE
13h 44m
1 stop
United Airlines Logo
8:15 pm - 10:23 am
LSE
-
CHS
13h 08m
1 stop
$999United Airlines
Fri, May 29 - Tue, Jun 2

American Airlines flights from South Carolina to La Crosse

Our best American Airlines deals on South Carolina to La Crosse flight tickets
American Airlines
Mar 19
CHS12:25 pmCharleston
6h 34m
1 stop
LSE5:59 pmLa Crosse
Mar 24
LSE9:48 amLa Crosse
5h 56m
1 stop
CHS4:44 pmCharleston
$457
American Airlines
Mar 19
CHS7:10 amCharleston
4h 51m
1 stop
LSE11:01 amLa Crosse
Mar 24
LSE5:09 amLa Crosse
8h 53m
2 stops
CHS3:02 pmCharleston
$463
American Airlines
Mar 19
CHS2:43 pmCharleston
9h 53m
2 stops
LSE11:36 pmLa Crosse
Mar 24
LSE9:48 amLa Crosse
9h 58m
2 stops
CHS8:46 pmCharleston
$468

United Airlines flights from South Carolina to La Crosse

Our best United Airlines deals on South Carolina to La Crosse flight tickets
United Airlines
May 29
SAV11:30 amSavannah/Hilton Head
7h 40m
1 stop
LSE6:10 pmLa Crosse
Jun 2
LSE6:15 amLa Crosse
14h 25m
1 stop
SAV9:40 pmSavannah/Hilton Head
$921
United Airlines
May 29
CHS11:31 amCharleston
13h 44m
1 stop
LSE12:15 amLa Crosse
Jun 2
LSE8:15 pmLa Crosse
13h 08m
1 stop
CHS10:23 amCharleston
$999

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from South Carolina to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonLa Crosse

CHS - LSE

CHSLSE

Charleston

Thu 3/19

12:25 pm-5:59 pm

1 stop6h 34m

La Crosse

Tue 3/24

9:48 am-4:44 pm

1 stop5h 56m

$457

CharlestonLa Crosse

CHS - LSE

CHSLSE

Charleston

Thu 3/19

7:10 am-11:01 am

1 stop4h 51m

La Crosse

Tue 3/24

5:09 am-3:02 pm

2 stops8h 53m

$463

CharlestonLa Crosse

CHS - LSE

CHSLSE

Charleston

Thu 3/19

2:43 pm-11:36 pm

2 stops9h 53m

La Crosse

Tue 3/24

9:48 am-8:46 pm

2 stops9h 58m

$468

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Tue 3/17

11:59 am-5:59 pm

1 stop7h 00m

La Crosse

Tue 3/24

9:48 am-9:23 pm

2 stops10h 35m

$506

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Wed 3/11

2:55 pm-11:36 pm

2 stops9h 41m

La Crosse

Wed 3/18

11:34 am-9:44 pm

2 stops9h 10m

$511

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Tue 3/17

11:59 am-5:59 pm

1 stop7h 00m

La Crosse

Tue 3/24

9:48 am-4:30 pm

1 stop5h 42m

$530

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Thu 3/12

11:59 am-5:59 pm

1 stop7h 00m

La Crosse

Tue 3/24

9:48 am-9:23 pm

2 stops10h 35m

$533

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Wed 3/11

5:20 pm-11:36 pm

1 stop7h 16m

La Crosse

Wed 3/18

11:34 am-9:44 pm

2 stops9h 10m

$536

SavannahLa Crosse

SAV - LSE

SAVLSE

Savannah/Hilton Head

Thu 3/12

11:59 am-5:59 pm

1 stop7h 00m

La Crosse

Tue 3/24

9:48 am-4:30 pm

1 stop5h 42m

$557

CharlestonLa Crosse

CHS - LSE

CHSLSE

Charleston

Fri 5/29

11:31 am-12:15 am

1 stop13h 44m

La Crosse

Tue 6/2

8:15 pm-10:23 am

1 stop13h 08m

$999

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to La Crosse from

How to get the cheapest flight ticket from South Carolina to La Crosse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to La Crosse flights?

You could potentially save up to 32% on your flight if you consider stops on a South Carolina to La Crosse flight.

Cheap South Carolina to La Crosse flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to La Crosse

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from South Carolina to La Crosse takes 5h 57m
There are no direct flights from South Carolina to La Crosse. There are no popular flight routes from South Carolina to La Crosse.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to La Crosse Airport?

    Prices for flights from South Carolina to La Crosse Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to La Crosse Airport?

  • How old do you have to be to fly from South Carolina to La Crosse Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The required travel and health documents for your La Crosse Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at La Crosse Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to La Crosse

Compare and see reviews for airlines that fly from South Carolina to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $507Free CancellationRating
7.2
11,248 reviews
Search American Airlines flights

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to La Crosse?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to La Crosse. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to La Crosse with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to La Crosse from South Carolina with this policy.

How can momondo help me find flights from South Carolina to La Crosse?

momondo provides multiple filters to help you find the best flight to La Crosse from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to La Crosse right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to La Crosse now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to La Crosse and let you know when they change.

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