Cheap flights from South Carolina to Washington, D.C. from $28

If you’re not able to fly to Baltimore in May, then August is your next best option. Flight prices from South Carolina to Baltimore during August average around $258.

The cheapest day to depart from South Carolina to Baltimore is on a Thursday. Travelers who choose to depart for Baltimore on a Thursday will often find tickets for as low as $329. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $478. These prices are subject to change though, so be sure to set up a Price Alert for flights to Baltimore.

Flying to Baltimore from South Carolina in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $300 when looking at flights departing in the afternoon. Flights in the morning are often more expensive with an average ticket price of $372.

Fly from Greenville to Baltimore/Washington for the best South Carolina - Baltimore/Washington flight prices

You are more likely to see cheaper flights to Baltimore from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Baltimore for around $308 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Baltimore from South Carolina for as low as $208 on momondo.

There is only 1 cabin class available to choose from on South Carolina to Baltimore/Washington flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Spirit Airlines, Southwest, and Delta are the most popular carriers operating from South Carolina to Baltimore/Washington

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to Baltimore from South Carolina according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Baltimore. Keep in mind that there are 5 different airlines that fly to Baltimore on a routine basis, so you have a few additional options to choose from.

As of February 2026, 18 flights take off from South Carolina and land in Baltimore each day. The most common flight departure time for this route is 7:00PM, with 45% of daily flights taking off at noon.

As of February 2026, 126 flights take off from South Carolina and land in Baltimore each week. The most common flight departure day for this route is Thu, with 20% of weekly flights taking off on this day.