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Cheap flights from San Luis Obispo to Des Moines from $349

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Luis Obispo to Des Moines departing on 8/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Luis Obispo to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:45 pm - 8:34 pm
SBP
-
DSM
5h 49m
1 stop
American Airlines Logo
5:45 am - 11:58 am
DSM
-
SBP
8h 13m
1 stop
$349American Airlines
Wed, Aug 12 - Sat, Aug 15
American Airlines Logo
6:52 pm - 9:11 am
SBP
-
DSM
12h 19m
2 stops
American Airlines Logo
5:25 am - 12:01 pm
DSM
-
SBP
8h 36m
1 stop
$389American Airlines
Tue, May 26 - Sat, May 30
United Airlines Logo
7:16 am - 8:16 pm
SBP
-
DSM
11h 00m
2 stops
United Airlines Logo
5:17 pm - 9:16 pm
DSM
-
SBP
5h 59m
1 stop
$424United Airlines
Tue, May 12 - Sat, May 16
American Airlines Logo
6:52 pm - 9:11 am
SBP
-
DSM
12h 19m
2 stops
American Airlines Logo
1:48 pm - 10:45 pm
DSM
-
SBP
10h 57m
2 stops
$429American Airlines
Tue, May 26 - Sat, May 30
American Airlines Logo
6:52 pm - 9:11 am
SBP
-
DSM
12h 19m
2 stops
American Airlines Logo
2:24 pm - 6:20 pm
DSM
-
SBP
5h 56m
1 stop
$444American Airlines
Tue, May 26 - Sat, May 30
United Airlines Logo
12:43 pm - 8:17 pm
SBP
-
DSM
5h 34m
1 stop
United Airlines Logo
5:50 am - 11:41 am
DSM
-
SBP
7h 51m
2 stops
$450United Airlines
Wed, Aug 12 - Sat, Aug 15
United Airlines Logo
8:28 pm - 10:11 am
SBP
-
DSM
11h 43m
2 stops
United Airlines Logo
5:50 am - 11:41 am
DSM
-
SBP
7h 51m
2 stops
$459United Airlines
Wed, Aug 12 - Sat, Aug 15
United Airlines Logo
6:05 am - 4:15 pm
SBP
-
DSM
8h 10m
2 stops
United Airlines Logo
8:00 am - 5:11 pm
DSM
-
SBP
11h 11m
2 stops
$464United Airlines
Tue, May 12 - Sat, May 16
American Airlines Logo
6:52 pm - 9:11 am
SBP
-
DSM
12h 19m
2 stops
American Airlines Logo
1:48 pm - 10:45 pm
DSM
-
SBP
10h 57m
2 stops
$474American Airlines
Tue, May 26 - Sat, May 30
American Airlines Logo
6:00 am - 1:44 pm
SBP
-
DSM
5h 44m
1 stop
American Airlines Logo
5:25 am - 12:01 pm
DSM
-
SBP
8h 36m
1 stop
$494American Airlines
Tue, May 26 - Sat, May 30

American Airlines flights from San Luis Obispo to Des Moines

Our best American Airlines deals on San Luis Obispo to Des Moines flight tickets
American Airlines
Aug 12
SBP12:45 pmSan Luis Obispo County
5h 49m
1 stop
DSM8:34 pmDes Moines
Aug 15
DSM5:45 amDes Moines
8h 13m
1 stop
SBP11:58 amSan Luis Obispo County
$349
American Airlines
May 26
SBP6:52 pmSan Luis Obispo County
12h 19m
2 stops
DSM9:11 amDes Moines
May 30
DSM5:25 amDes Moines
8h 36m
1 stop
SBP12:01 pmSan Luis Obispo County
$389
American Airlines
May 26
SBP6:52 pmSan Luis Obispo County
12h 19m
2 stops
DSM9:11 amDes Moines
May 30
DSM1:48 pmDes Moines
10h 57m
2 stops
SBP10:45 pmSan Luis Obispo County
$429

United Airlines flights from San Luis Obispo to Des Moines

Our best United Airlines deals on San Luis Obispo to Des Moines flight tickets
United Airlines
Aug 12
SBP12:43 pmSan Luis Obispo County
5h 34m
1 stop
DSM8:17 pmDes Moines
Aug 15
DSM5:50 amDes Moines
7h 51m
2 stops
SBP11:41 amSan Luis Obispo County
$450
United Airlines
Aug 12
SBP8:28 pmSan Luis Obispo County
11h 43m
2 stops
DSM10:11 amDes Moines
Aug 15
DSM5:50 amDes Moines
7h 51m
2 stops
SBP11:41 amSan Luis Obispo County
$459
United Airlines
May 26
SBP6:05 pmSan Luis Obispo County
16h 31m
3 stops
DSM12:36 pmDes Moines
May 30
DSM11:23 amDes Moines
14h 21m
2 stops
SBP11:44 pmSan Luis Obispo County
$676

momondo Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 2, 2026.
Use the filters below to find and compare flights from San Luis Obispo to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Wed 8/12

12:45 pm-8:34 pm

1 stop5h 49m

Des Moines

Sat 8/15

5:45 am-11:58 am

1 stop8h 13m

$349

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/26

6:52 pm-9:11 am

2 stops12h 19m

Des Moines

Sat 5/30

5:25 am-12:01 pm

1 stop8h 36m

$389

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/12

7:16 am-8:16 pm

2 stops11h 00m

Des Moines

Sat 5/16

5:17 pm-9:16 pm

1 stop5h 59m

$424

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/26

6:52 pm-9:11 am

2 stops12h 19m

Des Moines

Sat 5/30

1:48 pm-10:45 pm

2 stops10h 57m

$429

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/26

6:52 pm-9:11 am

2 stops12h 19m

Des Moines

Sat 5/30

2:24 pm-6:20 pm

1 stop5h 56m

$444
Quickest round-trip

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Wed 8/12

12:43 pm-8:17 pm

1 stop5h 34m

Des Moines

Sat 8/15

5:50 am-11:41 am

2 stops7h 51m

$450

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Wed 8/12

8:28 pm-10:11 am

2 stops11h 43m

Des Moines

Sat 8/15

5:50 am-11:41 am

2 stops7h 51m

$459

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/12

6:05 am-4:15 pm

2 stops8h 10m

Des Moines

Sat 5/16

8:00 am-5:11 pm

2 stops11h 11m

$464

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/26

6:52 pm-9:11 am

2 stops12h 19m

Des Moines

Sat 5/30

1:48 pm-10:45 pm

2 stops10h 57m

$474

San Luis ObispoDes Moines

SBP - DSM

SBPDSM

San Luis Obispo County

Tue 5/26

6:00 am-1:44 pm

1 stop5h 44m

Des Moines

Sat 5/30

5:25 am-12:01 pm

1 stop8h 36m

$494

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Luis Obispo to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from San Luis Obispo County to Des Moines?

American Airlines is the most popular carrier operating from San Luis Obispo County to Des Moines

When to book flights from San Luis Obispo to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Luis Obispo to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Luis Obispo to Des Moines (SBP to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Luis Obispo to Des Moines

Fastest flight time

5h 34m

Direct flights

None
The fastest flight from San Luis Obispo to Des Moines takes 5h 34m
There are no direct flights from San Luis Obispo to Des Moines. There are no popular flight routes from San Luis Obispo to Des Moines.
Search flight deals

Frequently asked questions about flying from San Luis Obispo to Des Moines

  • How far is San Luis Obispo County to Des Moines by plane?

    A flight from San Luis Obispo County to Des Moines will travel around 1518.2 mi. 5h 34m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Luis Obispo County Airport to Des Moines Airport?

    Prices for flights from San Luis Obispo County Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Luis Obispo County Airport to Des Moines Airport?

  • How old do you have to be to fly from San Luis Obispo County Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Luis Obispo County Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Luis Obispo to Des Moines?

Best airlines flying from San Luis Obispo to Des Moines

Compare and see reviews for airlines that fly from San Luis Obispo to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $353Free CancellationRating
7.1
11,676 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Luis Obispo to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Luis Obispo to Des Moines for you.

Can I find flights from San Luis Obispo to Des Moines with flexible booking policies on momondo?

Flights from San Luis Obispo to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Luis Obispo to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Luis Obispo to Des Moines.

I’m not ready to book a flight from San Luis Obispo to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Luis Obispo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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