What airlines fly to South America?

United Airlines, American Airlines and Copa Airlines are the top three most popular airlines that fly to South America from San Antonio according to our data. United Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Antonio to South America?

Spirit Airlines, Viva, and United Airlines are the most popular carriers operating from San Antonio to South America

When did momondo last update prices for flights from San Antonio Airport to South America?

Prices for flights from San Antonio Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from San Antonio Airport to South America?

As of April 2026, there are 5 operators available to choose from for flights from San Antonio Airport to South America.

How old do you have to be to fly from San Antonio Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$142 Cheap Flights from San Antonio to South America in 2026

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Find the cheapest flights from San Antonio to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:12 pm - 1:08 pm

SAT

MDE

22h 56m

2 stops

2:06 pm - 11:51 pm

MDE

SAT

9h 45m

1 stop

$354Spirit Airlines

Sat, Apr 18 - Sat, Apr 25

2:12 pm - 1:08 pm

SAT

MDE

22h 56m

2 stops

2:06 pm - 11:51 pm

MDE

SAT

9h 45m

1 stop

$355Spirit Airlines

Sat, Apr 18 - Sat, Apr 25

5:20 am - 1:40 pm

SAT

BOG

8h 20m

1 stop

9:00 am - 8:30 pm

BOG

SAT

11h 30m

1 stop

$474Delta

Wed, Apr 15 - Fri, Apr 24

11:45 am - 11:36 pm

SAT

CLO

11h 51m

2 stops

12:06 pm - 8:42 am

CLO

SAT

20h 36m

2 stops

$564United Airlines

Thu, May 14 - Mon, May 18

9:50 am - 8:20 pm

SAT

PEI

10h 30m

2 stops

5:15 am - 7:40 pm

PEI

SAT

14h 25m

2 stops

$575United Airlines

Tue, May 12 - Thu, May 14

6:19 pm - 10:30 pm

SAT

PEI

28h 11m

3 stops

8:10 am - 12:30 am

PEI

SAT

16h 20m

3 stops

$626LATAM Airlines

Fri, Jun 12 - Mon, Jun 15

5:06 am - 11:55 pm

SAT

UIO

18h 49m

1 stop

6:40 am - 11:23 pm

UIO

SAT

16h 43m

1 stop

$647American Airlines

Sat, Aug 15 - Tue, Sep 15

5:25 am - 6:59 pm

SAT

UIO

13h 34m

1 stop

12:59 am - 1:31 pm

UIO

SAT

12h 32m

1 stop

$657Delta

Sat, May 16 - Fri, May 22

5:01 am - 11:58 pm

SAT

UIO

18h 57m

1 stop

6:09 am - 11:25 pm

UIO

SAT

17h 16m

1 stop

$667American Airlines

Wed, Jul 22 - Wed, Aug 19

6:21 pm - 6:59 pm

SAT

UIO

24h 38m

1 stop

12:59 am - 11:03 am

UIO

SAT

10h 04m

1 stop

$670LATAM Airlines

Fri, May 29 - Thu, Jun 4

Delta flights from San Antonio to South America

Our best Delta deals on San Antonio to South America flight tickets

Delta

Apr 15

SAT5:20 amSan Antonio

8h 20m

1 stop

BOG1:40 pmBogotá El Dorado

Apr 24

BOG9:00 amBogotá El Dorado

11h 30m

1 stop

SAT8:30 pmSan Antonio

$474

Delta

Sep 7

SAT4:25 pmSan Antonio

19h 40m

2 stops

BOG12:05 pmBogotá El Dorado

Sep 12

BOG2:55 pmBogotá El Dorado

9h 20m

1 stop

SAT12:15 amSan Antonio

$475

Delta

Apr 2

SAT5:10 amSan Antonio

8h 30m

1 stop

BOG1:40 pmBogotá El Dorado

Apr 7

BOG5:00 amBogotá El Dorado

19h 38m

2 stops

SAT12:38 amSan Antonio

$497

American Airlines flights from San Antonio to South America

Our best American Airlines deals on San Antonio to South America flight tickets

American Airlines

May 12

SAT8:15 amSan Antonio

14h 15m

1 stop

BOG10:30 pmBogotá El Dorado

May 19

BOG6:30 amBogotá El Dorado

16h 45m

1 stop

SAT11:15 pmSan Antonio

$491

American Airlines

May 13

SAT5:25 amSan Antonio

7h 23m

1 stop

MDE12:48 pmMedellín Jose Maria Cordova Intl

May 20

MDE6:00 amMedellín Jose Maria Cordova Intl

10h 39m

1 stop

SAT4:39 pmSan Antonio

$567

American Airlines

May 13

SAT9:36 amSan Antonio

10h 39m

2 stops

MDE8:15 pmMedellín Jose Maria Cordova Intl

May 20

MDE11:59 pmMedellín Jose Maria Cordova Intl

11h 55m

2 stops

SAT11:54 amSan Antonio

$570

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sat 4/18

2:12 pm-1:08 pm

2 stops22h 56m

Medellín Jose Maria Cordova Intl

Sat 4/25

2:06 pm-11:51 pm

1 stop9h 45m

$354

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sat 4/18

2:12 pm-1:08 pm

2 stops22h 56m

Medellín Jose Maria Cordova Intl

Sat 4/25

2:06 pm-11:51 pm

1 stop9h 45m

$355

Quickest round-trip

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Wed 4/15

5:20 am-1:40 pm

1 stop8h 20m

Bogotá El Dorado

Fri 4/24

9:00 am-8:30 pm

1 stop11h 30m

$474

San AntonioCali

SAT - CLO

SATCLO

San Antonio

Thu 5/14

11:45 am-11:36 pm

2 stops11h 51m

Cali Alfonso B. Aragon Intl

Mon 5/18

12:06 pm-8:42 am

2 stops20h 36m

$564

San AntonioPereira

SAT - PEI

SATPEI

San Antonio

Tue 5/12

9:50 am-8:20 pm

2 stops10h 30m

Pereira Matecana

Thu 5/14

5:15 am-7:40 pm

2 stops14h 25m

$575

San AntonioPereira

SAT - PEI

SATPEI

San Antonio

Fri 6/12

6:19 pm-10:30 pm

3 stops28h 11m

Pereira Matecana

Mon 6/15

8:10 am-12:30 am

3 stops16h 20m

$626

San AntonioQuito

SAT - UIO

SATUIO

San Antonio

Sat 8/15

5:06 am-11:55 pm

1 stop18h 49m

Quito Mariscal Sucr

Tue 9/15

6:40 am-11:23 pm

1 stop16h 43m

$647

San AntonioQuito

SAT - UIO

SATUIO

San Antonio

Sat 5/16

5:25 am-6:59 pm

1 stop13h 34m

Quito Mariscal Sucr

Fri 5/22

12:59 am-1:31 pm

1 stop12h 32m

$657

San AntonioQuito

SAT - UIO

SATUIO

San Antonio

Wed 7/22

5:01 am-11:58 pm

1 stop18h 57m

Quito Mariscal Sucr

Wed 8/19

6:09 am-11:25 pm

1 stop17h 16m

$667

San AntonioQuito

SAT - UIO

SATUIO

San Antonio

Fri 5/29

6:21 pm-6:59 pm

1 stop24h 38m

Quito Mariscal Sucr

Thu 6/4

12:59 am-11:03 am

1 stop10h 04m

$670

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Antonio to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, March is the cheapest month to fly from San Antonio to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $542. If you aren’t able to travel during the month of March, then book flights to South America from San Antonio during February instead. Flights to South America in February, while not as cheap as those in March, still average around $615.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Antonio when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $717 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Antonio for as low as $598 on momondo.

Can stopping save me money on San Antonio to South America flights?

You could potentially save up to 36% on your flight if you consider stops on a San Antonio to South America flight.

Cheap San Antonio to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to South America

Fastest flight time	6h 55m
Direct flights	None

The fastest flight from San Antonio to South America takes 6h 55m

There are no direct flights from San Antonio to South America. There are no popular flight routes from San Antonio to South America.

Search flight deals

Frequently asked questions about flying from San Antonio to South America

When did momondo last update prices for flights from San Antonio Airport to South America?
Prices for flights from San Antonio Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from San Antonio Airport to South America?
As of April 2026, there are 5 operators available to choose from for flights from San Antonio Airport to South America.
How old do you have to be to fly from San Antonio Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from San Antonio to South America

Compare and see reviews for airlines that fly from San Antonio to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $285	Free Cancellation	Rating 6.3 8,578 reviews	Search Spirit Airlines flights
Delta	PriceFrom $414	Free Cancellation	Rating 7.9 8,366 reviews	Search Delta flights
American Airlines	PriceFrom $414	Free Cancellation	Rating 7.1 11,549 reviews	Search American Airlines flights
United Airlines	PriceFrom $414	Free Cancellation	Rating 7.4 9,534 reviews	Search United Airlines flights
LATAM Airlines	PriceFrom $419	Free Cancellation	Rating 7.4 1,907 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from San Antonio.

Can I find flights from San Antonio to South America with flexible booking policies on momondo?

All flight searches from San Antonio to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Antonio to South America?

Once you have performed a search for San Antonio to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Antonio to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Antonio to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.