What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Roanoke according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Roanoke Airport to South America?

Prices for flights from Roanoke Airport to South America refresh daily.

How old do you have to be to fly from Roanoke Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$721 Cheap Flights from Roanoke to South America in 2026

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Find the cheapest flights from Roanoke to South America

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:34 am - 11:25 pm

ROA

UIO

37h 51m

2 stops

7:25 am - 1:33 pm

UIO

ROA

29h 08m

2 stops

$721United Airlines

Sat, May 16 - Mon, May 25

6:00 am - 11:25 pm

ROA

UIO

18h 25m

2 stops

12:35 am - 9:49 am

UIO

ROA

32h 14m

2 stops

$757United Airlines

Fri, May 1 - Fri, May 8

8:55 am - 11:59 pm

ROA

UIO

16h 04m

2 stops

11:59 pm - 9:20 pm

UIO

ROA

20h 21m

2 stops

$776American Airlines

Sat, May 23 - Sat, May 30

6:00 am - 5:00 am

ROA

UIO

48h 00m

2 stops

7:25 am - 1:33 pm

UIO

ROA

29h 08m

2 stops

$814United Airlines

Fri, May 15 - Mon, May 25

11:08 am - 6:59 pm

ROA

UIO

8h 51m

1 stop

12:59 am - 10:30 am

UIO

ROA

8h 31m

1 stop

$817LATAM Airlines

Fri, May 1 - Fri, May 8

7:05 am - 4:43 am

ROA

UIO

22h 38m

2 stops

6:50 pm - 10:34 am

UIO

ROA

14h 44m

2 stops

$818Delta

Mon, Jun 1 - Fri, Jul 31

11:08 am - 6:59 pm

ROA

UIO

8h 51m

1 stop

6:50 pm - 2:50 pm

UIO

ROA

19h 00m

2 stops

$822LATAM Airlines

Fri, May 1 - Sat, May 9

7:05 am - 4:43 am

ROA

UIO

22h 38m

2 stops

12:59 am - 10:30 am

UIO

ROA

8h 31m

1 stop

$849Delta

Sat, May 16 - Sun, May 24

5:00 pm - 6:59 pm

ROA

UIO

26h 59m

1 stop

12:59 am - 10:30 am

UIO

ROA

8h 31m

1 stop

$854LATAM Airlines

Sat, May 16 - Sun, May 24

8:55 am - 7:05 am

ROA

SCL

22h 10m

2 stops

9:00 pm - 5:39 pm

SCL

ROA

20h 39m

2 stops

$1,280American Airlines

Sun, May 24 - Sun, May 31

American Airlines flights from Roanoke to South America

Our best American Airlines deals on Roanoke to South America flight tickets

American Airlines

May 23

ROA8:55 amRoanoke

16h 04m

2 stops

UIO11:59 pmQuito Mariscal Sucr

May 30

UIO11:59 pmQuito Mariscal Sucr

20h 21m

2 stops

ROA9:20 pmRoanoke

$776

American Airlines

May 24

ROA8:55 amRoanoke

22h 10m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 31

SCL9:00 pmSantiago Arturo Merino Benitez

20h 39m

2 stops

ROA5:39 pmRoanoke

$1,280

LATAM Airlines flights from Roanoke to South America

Our best LATAM Airlines deals on Roanoke to South America flight tickets

LATAM Airlines

May 1

ROA11:08 amRoanoke

8h 51m

1 stop

UIO6:59 pmQuito Mariscal Sucr

May 8

UIO12:59 amQuito Mariscal Sucr

8h 31m

1 stop

ROA10:30 amRoanoke

$817

LATAM Airlines

May 1

ROA11:08 amRoanoke

8h 51m

1 stop

UIO6:59 pmQuito Mariscal Sucr

May 9

UIO6:50 pmQuito Mariscal Sucr

19h 00m

2 stops

ROA2:50 pmRoanoke

$822

LATAM Airlines

May 16

ROA5:00 pmRoanoke

26h 59m

1 stop

UIO6:59 pmQuito Mariscal Sucr

May 24

UIO12:59 amQuito Mariscal Sucr

8h 31m

1 stop

ROA10:30 amRoanoke

$854

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

10:34 am-11:25 pm

2 stops37h 51m

Quito Mariscal Sucr

Mon 5/25

7:25 am-1:33 pm

2 stops29h 08m

$721

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 5/1

6:00 am-11:25 pm

2 stops18h 25m

Quito Mariscal Sucr

Fri 5/8

12:35 am-9:49 am

2 stops32h 14m

$757

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/23

8:55 am-11:59 pm

2 stops16h 04m

Quito Mariscal Sucr

Sat 5/30

11:59 pm-9:20 pm

2 stops20h 21m

$776

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 5/15

6:00 am-5:00 am

2 stops48h 00m

Quito Mariscal Sucr

Mon 5/25

7:25 am-1:33 pm

2 stops29h 08m

$814

Quickest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 5/1

11:08 am-6:59 pm

1 stop8h 51m

Quito Mariscal Sucr

Fri 5/8

12:59 am-10:30 am

1 stop8h 31m

$817

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Mon 6/1

7:05 am-4:43 am

2 stops22h 38m

Quito Mariscal Sucr

Fri 7/31

6:50 pm-10:34 am

2 stops14h 44m

$818

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 5/1

11:08 am-6:59 pm

1 stop8h 51m

Quito Mariscal Sucr

Sat 5/9

6:50 pm-2:50 pm

2 stops19h 00m

$822

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

7:05 am-4:43 am

2 stops22h 38m

Quito Mariscal Sucr

Sun 5/24

12:59 am-10:30 am

1 stop8h 31m

$849

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

5:00 pm-6:59 pm

1 stop26h 59m

Quito Mariscal Sucr

Sun 5/24

12:59 am-10:30 am

1 stop8h 31m

$854

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Sun 5/24

8:55 am-7:05 am

2 stops22h 10m

Santiago Arturo Merino Benitez

Sun 5/31

9:00 pm-5:39 pm

2 stops20h 39m

$1,280

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Roanoke to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Roanoke to South America flights?

You could potentially save up to 1% on your flight if you consider stops on a Roanoke to South America flight.

Cheap Roanoke to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South America

Fastest flight time	13h 25m
Direct flights	None

The fastest flight from Roanoke to South America takes 13h 25m

There are no direct flights from Roanoke to South America. There are no popular flight routes from Roanoke to South America.

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Frequently asked questions about flying from Roanoke to South America

When did momondo last update prices for flights from Roanoke Airport to South America?
Prices for flights from Roanoke Airport to South America refresh daily.
How old do you have to be to fly from Roanoke Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South America

Compare and see reviews for airlines that fly from Roanoke to South America with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $662	Free Cancellation	Rating 7.4 1,909 reviews		Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South America?

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Can I find flights from Roanoke to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Roanoke with this policy.

How can momondo help me find flights from Roanoke to South America?

Once all potential Roanoke to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.