What airlines fly to South America?

Delta, LATAM Airlines and American Airlines are the top three most popular airlines that fly to South America from Roanoke according to our data. Delta is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Roanoke Airport to South America?

Prices for flights from Roanoke Airport to South America refresh daily.

How old do you have to be to fly from Roanoke Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$758 Cheap Flights from Roanoke to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to South America

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 11:25 pm

ROA

UIO

18h 10m

2 stops

12:35 am - 9:42 am

UIO

ROA

32h 07m

2 stops

$892United Airlines

Wed, Jul 29 - Fri, Jul 31

2:23 pm - 6:25 am

ROA

SCL

16h 02m

2 stops

8:50 pm - 2:30 pm

SCL

ROA

17h 40m

2 stops

$952American Airlines

Tue, Aug 18 - Sun, Aug 23

8:10 am - 10:37 pm

ROA

GYE

15h 27m

2 stops

6:00 am - 10:18 pm

GYE

ROA

15h 18m

2 stops

$965American Airlines

Wed, Jul 29 - Sat, Aug 1

7:59 pm - 6:59 pm

ROA

UIO

24h 00m

1 stop

12:59 am - 10:30 am

UIO

ROA

8h 31m

1 stop

$993LATAM Airlines

Wed, Jul 29 - Fri, Jul 31

6:00 am - 11:00 pm

ROA

UIO

18h 00m

2 stops

12:59 am - 10:30 am

UIO

ROA

8h 31m

1 stop

$1,012LATAM Airlines

Wed, Jul 29 - Fri, Jul 31

6:00 am - 6:00 am

ROA

SCL

23h 00m

2 stops

8:40 pm - 10:33 am

SCL

ROA

14h 53m

1 stop

$1,027Delta

Tue, Oct 6 - Tue, Oct 20

6:40 am - 7:40 am

ROA

GIG

24h 00m

2 stops

10:30 am - 9:41 am

GIG

ROA

24h 11m

2 stops

$1,040Copa Airlines

Tue, Aug 4 - Tue, Aug 11

8:05 pm - 12:25 am

ROA

GIG

27h 20m

2 stops

1:25 am - 9:41 am

GIG

ROA

33h 16m

2 stops

$1,049Copa Airlines

Tue, Aug 11 - Mon, Aug 17

11:18 am - 7:15 am

ROA

SCL

19h 57m

1 stop

8:40 pm - 7:19 pm

SCL

ROA

22h 39m

1 stop

$1,057Delta

Tue, Aug 18 - Sun, Aug 23

5:52 pm - 4:45 pm

ROA

SDU

21h 53m

2 stops

1:45 pm - 7:07 pm

SDU

ROA

30h 22m

2 stops

$1,415Multiple Airlines

Tue, Aug 4 - Tue, Aug 11

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Delta flights from Roanoke to South America

Our best Delta deals on Roanoke to South America flight tickets

Delta

Oct 6

ROA6:00 amRoanoke

23h 00m

2 stops

SCL6:00 amSantiago Arturo Merino Benitez

Oct 20

SCL8:40 pmSantiago Arturo Merino Benitez

14h 53m

1 stop

ROA10:33 amRoanoke

$1,027

Delta

Aug 18

ROA11:18 amRoanoke

19h 57m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Aug 23

SCL8:40 pmSantiago Arturo Merino Benitez

22h 39m

1 stop

ROA7:19 pmRoanoke

$1,057

Delta

Aug 10

ROA11:18 amRoanoke

21h 57m

1 stop

GIG10:15 amRio de Janeiro–Galeão Intl

Aug 20

GIG7:10 amRio de Janeiro–Galeão Intl

18h 17m

2 stops

ROA12:27 amRoanoke

$1,263

LATAM Airlines flights from Roanoke to South America

Our best LATAM Airlines deals on Roanoke to South America flight tickets

LATAM Airlines

Jul 29

ROA7:59 pmRoanoke

24h 00m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Jul 31

UIO12:59 amQuito Mariscal Sucr

8h 31m

1 stop

ROA10:30 amRoanoke

$993

LATAM Airlines

Jul 29

ROA6:00 amRoanoke

18h 00m

2 stops

UIO11:00 pmQuito Mariscal Sucr

Jul 31

UIO12:59 amQuito Mariscal Sucr

8h 31m

1 stop

ROA10:30 amRoanoke

$1,012

LATAM Airlines

Oct 6

ROA3:32 pmRoanoke

20h 53m

3 stops

SCL1:25 pmSantiago Arturo Merino Benitez

Oct 20

SCL7:50 amSantiago Arturo Merino Benitez

17h 38m

2 stops

ROA12:28 amRoanoke

$1,032

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Wed 7/29

6:15 am-11:25 pm

2 stops18h 10m

Quito Mariscal Sucr

Fri 7/31

12:35 am-9:42 am

2 stops32h 07m

$892

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 8/18

2:23 pm-6:25 am

2 stops16h 02m

Santiago Arturo Merino Benitez

Sun 8/23

8:50 pm-2:30 pm

2 stops17h 40m

$952

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Wed 7/29

8:10 am-10:37 pm

2 stops15h 27m

Guayaquil Jose Joaquin de Olmedo

Sat 8/1

6:00 am-10:18 pm

2 stops15h 18m

$965

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Wed 7/29

7:59 pm-6:59 pm

1 stop24h 00m

Quito Mariscal Sucr

Fri 7/31

12:59 am-10:30 am

1 stop8h 31m

$993

Quickest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Wed 7/29

6:00 am-11:00 pm

2 stops18h 00m

Quito Mariscal Sucr

Fri 7/31

12:59 am-10:30 am

1 stop8h 31m

$1,012

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 10/6

6:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Tue 10/20

8:40 pm-10:33 am

1 stop14h 53m

$1,027

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Tue 8/4

6:40 am-7:40 am

2 stops24h 00m

Rio de Janeiro–Galeão Intl

Tue 8/11

10:30 am-9:41 am

2 stops24h 11m

$1,040

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Tue 8/11

8:05 pm-12:25 am

2 stops27h 20m

Rio de Janeiro–Galeão Intl

Mon 8/17

1:25 am-9:41 am

2 stops33h 16m

$1,049

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 8/18

11:18 am-7:15 am

1 stop19h 57m

Santiago Arturo Merino Benitez

Sun 8/23

8:40 pm-7:19 pm

1 stop22h 39m

$1,057

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Tue 8/4

5:52 pm-4:45 pm

2 stops21h 53m

Rio de Janeiro Santos Dumont

Tue 8/11

1:45 pm-7:07 pm

2 stops30h 22m

$1,415

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Roanoke to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, June is the cheapest month to fly from Roanoke to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of June, then book flights to South America from Roanoke during April instead. Flights to South America in April, while not as cheap as those in June, still average around $0.

Can stopping save me money on Roanoke to South America flights?

You could potentially save up to 1% on your flight if you consider stops on a Roanoke to South America flight.

Cheap Roanoke to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South America

Fastest flight time	12h 35m
Direct flights	None

The fastest flight from Roanoke to South America takes 12h 35m

There are no direct flights from Roanoke to South America. There are no popular flight routes from Roanoke to South America.

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Frequently asked questions about flying from Roanoke to South America

When did momondo last update prices for flights from Roanoke Airport to South America?
Prices for flights from Roanoke Airport to South America refresh daily.
How old do you have to be to fly from Roanoke Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South America

Compare and see reviews for airlines that fly from Roanoke to South America with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $662	Free Cancellation	Rating 7.4 1,950 reviews		Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Roanoke with this policy.

How can momondo help me find flights from Roanoke to South America?

Once all potential Roanoke to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.