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Cheap flights from Roanoke to South America from $415

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to South America departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
5:14 pm - 2:31 pmROA-GYE
21h 17m2 stops
American Airlines Logo
3:31 pm - 10:39 amGYE-ROA
19h 08m2 stops
$553American Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18
Multiple Airlines Logo
6:45 am - 11:42 pmROA-GYE
16h 57m2 stops
Multiple Airlines Logo
3:30 am - 8:07 pmGYE-ROA
16h 37m2 stops
$1,088Multiple Airlines
Find Deal
Wed, Feb 11 - Tue, Feb 17
Delta Logo
3:25 pm - 7:20 amROA-GIG
14h 55m1 stop
Delta Logo
7:15 am - 10:33 amGIG-ROA
28h 18m2 stops
$1,180Delta
Find Deal
Sat, Mar 21 - Wed, Mar 25
Delta Logo
3:25 pm - 7:20 amROA-GIG
14h 55m1 stop
Delta Logo
7:15 am - 11:49 pmGIG-ROA
17h 34m2 stops
$1,181Delta
Find Deal
Sat, Mar 21 - Wed, Mar 25
LATAM Airlines Logo
3:25 pm - 9:35 amROA-SDU
17h 10m2 stops
LATAM Airlines Logo
2:00 pm - 2:39 pmSDU-ROA
25h 39m2 stops
$1,198LATAM Airlines
Find Deal
Sat, Mar 21 - Wed, Mar 25
LATAM Airlines Logo
6:00 am - 8:20 amROA-GIG
24h 20m1 stop
LATAM Airlines Logo
9:30 pm - 8:38 pmGIG-ROA
25h 08m1 stop
$1,254LATAM Airlines
Find Deal
Wed, Dec 24 - Wed, Dec 31
American Airlines Logo
7:00 am - 6:15 amROA-GIG
21h 15m2 stops
American Airlines Logo
10:15 pm - 4:44 pmGIG-ROA
20h 29m2 stops
$1,445American Airlines
Find Deal
Wed, Dec 24 - Wed, Dec 31
LATAM Airlines Logo
6:00 am - 8:20 amROA-GIG
24h 20m1 stop
LATAM Airlines Logo
7:15 am - 8:38 pmGIG-ROA
39h 23m2 stops
$1,447LATAM Airlines
Find Deal
Wed, Dec 24 - Wed, Dec 31
Multiple Airlines Logo
10:32 am - 6:25 amROA-GIG
17h 53m2 stops
Multiple Airlines Logo
1:45 am - 6:51 pmGIG-ROA
19h 06m2 stops
$1,609Multiple Airlines
Find Deal
Wed, Dec 24 - Tue, Dec 30
Multiple Airlines Logo
10:15 am - 11:35 pmROA-GYE
13h 20m2 stops
Multiple Airlines Logo
10:25 am - 2:12 pmGYE-ROA
27h 47m3 stops
$1,689Multiple Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18

Delta flights from Roanoke to South America

Our best Delta deals on Roanoke to South America flight tickets
Delta
Mar 21
ROA3:25 pmRoanoke
14h 55m
1 stop
GIG7:20 amRio de Janeiro–Galeão Intl
Mar 25
GIG7:15 amRio de Janeiro–Galeão Intl
28h 18m
2 stops
ROA10:33 amRoanoke
$1,180
Find similar
Delta
Mar 21
ROA3:25 pmRoanoke
14h 55m
1 stop
GIG7:20 amRio de Janeiro–Galeão Intl
Mar 25
GIG7:15 amRio de Janeiro–Galeão Intl
17h 34m
2 stops
ROA11:49 pmRoanoke
$1,181
Find similar
Delta
Dec 24
ROA1:30 pmRoanoke
21h 45m
2 stops
SDU1:15 pmRio de Janeiro Santos Dumont
Dec 31
SDU8:05 pmRio de Janeiro Santos Dumont
18h 32m
2 stops
ROA12:37 pmRoanoke
$4,413
Find similar

LATAM Airlines flights from Roanoke to South America

Our best LATAM Airlines deals on Roanoke to South America flight tickets
LATAM Airlines
Mar 21
ROA3:25 pmRoanoke
17h 10m
2 stops
SDU9:35 amRio de Janeiro Santos Dumont
Mar 25
SDU2:00 pmRio de Janeiro Santos Dumont
25h 39m
2 stops
ROA2:39 pmRoanoke
$1,198
Find similar
LATAM Airlines
Dec 24
ROA6:00 amRoanoke
24h 20m
1 stop
GIG8:20 amRio de Janeiro–Galeão Intl
Dec 31
GIG9:30 pmRio de Janeiro–Galeão Intl
25h 08m
1 stop
ROA8:38 pmRoanoke
$1,254
Find similar
LATAM Airlines
Dec 24
ROA6:00 amRoanoke
24h 20m
1 stop
GIG8:20 amRio de Janeiro–Galeão Intl
Dec 31
GIG7:15 amRio de Janeiro–Galeão Intl
39h 23m
2 stops
ROA8:38 pmRoanoke
$1,447
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 9, 2025.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Wed 2/11

5:14 pm-2:31 pm

2 stops21h 17m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

3:31 pm-10:39 am

2 stops19h 08m

$553

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Wed 2/11

6:45 am-11:42 pm

2 stops16h 57m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

3:30 am-8:07 pm

2 stops16h 37m

$1,088

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Sat 3/21

3:25 pm-7:20 am

1 stop14h 55m

Rio de Janeiro–Galeão Intl

Wed 3/25

7:15 am-10:33 am

2 stops28h 18m

$1,180

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Sat 3/21

3:25 pm-7:20 am

1 stop14h 55m

Rio de Janeiro–Galeão Intl

Wed 3/25

7:15 am-11:49 pm

2 stops17h 34m

$1,181

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Sat 3/21

3:25 pm-9:35 am

2 stops17h 10m

Rio de Janeiro Santos Dumont

Wed 3/25

2:00 pm-2:39 pm

2 stops25h 39m

$1,198

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Wed 12/24

6:00 am-8:20 am

1 stop24h 20m

Rio de Janeiro–Galeão Intl

Wed 12/31

9:30 pm-8:38 pm

1 stop25h 08m

$1,254

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Wed 12/24

7:00 am-6:15 am

2 stops21h 15m

Rio de Janeiro–Galeão Intl

Wed 12/31

10:15 pm-4:44 pm

2 stops20h 29m

$1,445

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Wed 12/24

6:00 am-8:20 am

1 stop24h 20m

Rio de Janeiro–Galeão Intl

Wed 12/31

7:15 am-8:38 pm

2 stops39h 23m

$1,447

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Wed 12/24

10:32 am-6:25 am

2 stops17h 53m

Rio de Janeiro–Galeão Intl

Tue 12/30

1:45 am-6:51 pm

2 stops19h 06m

$1,609

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Wed 2/11

10:15 am-11:35 pm

2 stops13h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

10:25 am-2:12 pm

3 stops27h 47m

$1,689

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Roanoke to South America is on a Sunday when prices can be found for as low as $641. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Roanoke to South America for around $898.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Roanoke to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $473. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $733 on average. Flights to South America from Roanoke in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Roanoke to South America flights?

You could potentially save up to 17% on your flight if you consider stops on a Roanoke to South America flight.

Cheap Roanoke to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South America

Direct flights

None
There are no direct flights from Roanoke to South America. There are no popular flight routes from Roanoke to South America.
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  • When did momondo last update prices for flights from Roanoke Airport to South America?

    Prices for flights from Roanoke Airport to South America refresh daily.

  • How many operators does momondo search for flights from Roanoke Airport to South America?

  • How old do you have to be to fly from Roanoke Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South America

Compare and see reviews for airlines that fly from Roanoke to South America with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
DeltaPriceFrom $501Free CancellationRating
7.9
8,002 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Roanoke with this policy.

How can momondo help me find flights from Roanoke to South America?

Once all potential Roanoke to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South America trip

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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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