What airlines fly to Des Moines?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Des Moines from Roanoke according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 3 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Roanoke Airport to Des Moines Airport?

Prices for flights from Roanoke Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Roanoke Airport to Des Moines Airport?

As of November 2025, there are 2 operators available to choose from for flights from Roanoke Airport to Des Moines Airport.

How old do you have to be to fly from Roanoke Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Roanoke Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$206 Cheap Flights from Roanoke to Des Moines in 2025/26

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Find the cheapest flights from Roanoke to Des Moines

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 10:16 amROA-DSM

5h 16m1 stop

5:15 pm - 11:49 pmDSM-ROA

5h 34m1 stop

$249Delta

Find Deal

mié., abr. 15 - sáb., abr. 18

6:00 am - 10:16 amROA-DSM

5h 16m1 stop

5:15 pm - 11:49 pmDSM-ROA

5h 34m1 stop

$294Delta

Find Deal

mié., abr. 15 - sáb., abr. 18

6:00 am - 10:16 amROA-DSM

5h 16m1 stop

4:00 pm - 11:49 pmDSM-ROA

6h 49m2 stops

$299Delta

Find Deal

mié., abr. 15 - sáb., abr. 18

6:45 am - 12:14 pmROA-DSM

6h 29m1 stop

11:26 am - 4:56 pmDSM-ROA

4h 30m1 stop

$349United Airlines

Find Deal

jue., nov. 20 - lun., nov. 24

6:45 am - 4:12 pmROA-DSM

10h 27m2 stops

11:26 am - 4:56 pmDSM-ROA

4h 30m1 stop

$354United Airlines

Find Deal

jue., nov. 20 - lun., nov. 24

7:02 am - 1:16 pmROA-DSM

7h 14m1 stop

2:15 pm - 7:39 pmDSM-ROA

4h 24m1 stop

$429American Airlines

Find Deal

dom., nov. 23 - vie., nov. 28

6:20 am - 4:12 pmROA-DSM

10h 52m2 stops

11:26 am - 4:56 pmDSM-ROA

4h 30m1 stop

$460United Airlines

Find Deal

dom., nov. 23 - vie., nov. 28

7:00 am - 10:24 pmROA-DSM

16h 24m2 stops

4:00 pm - 11:49 pmDSM-ROA

6h 49m2 stops

$472Delta

Find Deal

mié., abr. 15 - sáb., abr. 18

7:00 am - 9:17 pmROA-DSM

15h 17m2 stops

4:00 pm - 11:49 pmDSM-ROA

6h 49m2 stops

$478Delta

Find Deal

mié., abr. 15 - sáb., abr. 18

6:45 am - 4:12 pmROA-DSM

10h 27m2 stops

9:01 am - 6:43 pmDSM-ROA

8h 42m2 stops

$480United Airlines

Find Deal

jue., nov. 20 - lun., nov. 24

Delta flights from Roanoke to Des Moines

Our best Delta deals on Roanoke to Des Moines flight tickets

Delta

Apr 15

ROA6:00 amRoanoke

5h 16m

1 stop

DSM10:16 amDes Moines

Apr 18

DSM5:15 pmDes Moines

5h 34m

1 stop

ROA11:49 pmRoanoke

$249

Find similar

Delta

Apr 15

ROA6:00 amRoanoke

5h 16m

1 stop

DSM10:16 amDes Moines

Apr 18

DSM5:15 pmDes Moines

5h 34m

1 stop

ROA11:49 pmRoanoke

$294

Find similar

Delta

Apr 15

ROA6:00 amRoanoke

5h 16m

1 stop

DSM10:16 amDes Moines

Apr 18

DSM4:00 pmDes Moines

6h 49m

2 stops

ROA11:49 pmRoanoke

$299

Find similar

United Airlines flights from Roanoke to Des Moines

Our best United Airlines deals on Roanoke to Des Moines flight tickets

United Airlines

Nov 20

ROA6:45 amRoanoke

6h 29m

1 stop

DSM12:14 pmDes Moines

Nov 24

DSM11:26 amDes Moines

4h 30m

1 stop

ROA4:56 pmRoanoke

$349

Find similar

United Airlines

Nov 20

ROA6:45 amRoanoke

10h 27m

2 stops

DSM4:12 pmDes Moines

Nov 24

DSM11:26 amDes Moines

4h 30m

1 stop

ROA4:56 pmRoanoke

$354

Find similar

United Airlines

Nov 23

ROA6:20 amRoanoke

10h 52m

2 stops

DSM4:12 pmDes Moines

Nov 28

DSM11:26 amDes Moines

4h 30m

1 stop

ROA4:56 pmRoanoke

$460

Find similar

Fly from

Fly to

Route

Depart

Return

Price

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

mié. 4/15

6:00 am-10:16 am

1 stop5h 16m

Des Moines

sáb. 4/18

5:15 pm-11:49 pm

1 stop5h 34m

$249

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

mié. 4/15

6:00 am-10:16 am

1 stop5h 16m

Des Moines

sáb. 4/18

5:15 pm-11:49 pm

1 stop5h 34m

$294

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

mié. 4/15

6:00 am-10:16 am

1 stop5h 16m

Des Moines

sáb. 4/18

4:00 pm-11:49 pm

2 stops6h 49m

$299

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

jue. 11/20

6:45 am-12:14 pm

1 stop6h 29m

Des Moines

lun. 11/24

11:26 am-4:56 pm

1 stop4h 30m

$349

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

jue. 11/20

6:45 am-4:12 pm

2 stops10h 27m

Des Moines

lun. 11/24

11:26 am-4:56 pm

1 stop4h 30m

$354

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

dom. 11/23

7:02 am-1:16 pm

1 stop7h 14m

Des Moines

vie. 11/28

2:15 pm-7:39 pm

1 stop4h 24m

$429

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

dom. 11/23

6:20 am-4:12 pm

2 stops10h 52m

Des Moines

vie. 11/28

11:26 am-4:56 pm

1 stop4h 30m

$460

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

mié. 4/15

7:00 am-10:24 pm

2 stops16h 24m

Des Moines

sáb. 4/18

4:00 pm-11:49 pm

2 stops6h 49m

$472

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

mié. 4/15

7:00 am-9:17 pm

2 stops15h 17m

Des Moines

sáb. 4/18

4:00 pm-11:49 pm

2 stops6h 49m

$478

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

jue. 11/20

6:45 am-4:12 pm

2 stops10h 27m

Des Moines

lun. 11/24

9:01 am-6:43 pm

2 stops8h 42m

$480

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Roanoke to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $248. Flights from Roanoke to Des Moines on a Sunday will generally be more expensive and average around $545. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Roanoke to Des Moines at noon for as low as $306. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $377. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Roanoke to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Roanoke to Des Moines (ROA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Des Moines

Direct flights	None

There are no direct flights from Roanoke to Des Moines. There are no popular flight routes from Roanoke to Des Moines.

Search flight deals

How far is Roanoke to Des Moines by plane?
The distance between Roanoke and Des Moines is about 787.3 mi. Typically, this will take 5h 16m by plane in normal conditions.
When did momondo last update prices for flights from Roanoke Airport to Des Moines Airport?
Prices for flights from Roanoke Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Roanoke Airport to Des Moines Airport?
As of November 2025, there are 2 operators available to choose from for flights from Roanoke Airport to Des Moines Airport.
How old do you have to be to fly from Roanoke Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Roanoke Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Roanoke to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Roanoke to Des Moines is American Airlines (72% of total bookings). The next most popular airline is United Airlines (28%).

Best airlines flying from Roanoke to Des Moines

Compare and see reviews for airlines that fly from Roanoke to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,007 reviews		Search United Airlines flights
American Airlines	PriceFrom $283	Free Cancellation	Rating 7.2 11,040 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Newton

Pella

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Roanoke.

I’m not ready to book a flight from Roanoke to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Roanoke and alert you when they change.