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Cheap flights from Roanoke to Des Moines from $339

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:49 amROA  Roanoke-DSM Des Moines
5h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:53 pm - 12:26 amDSM  Des Moines-ROA Roanoke
4h 33m1 stop Atlanta Hartsfield-Jackson
$339Delta
Fri, Dec 4 - Sun, Dec 6
United Airlines Logo
5:51 pm - 9:55 pmROA  Roanoke-DSM Des Moines
5h 04m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 1:26 pmDSM  Des Moines-ROA Roanoke
4h 26m1 stop Chicago O'Hare Intl
$339United Airlines
Tue, Oct 27 - Tue, Nov 3
American Airlines Logo
11:05 am - 7:01 pmROA  Roanoke-DSM Des Moines
8h 56m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
9:23 am - 4:22 pmDSM  Des Moines-ROA Roanoke
5h 59m1 stop Chicago O'Hare Intl
$344American Airlines
Fri, Dec 4 - Sun, Dec 6
United Airlines Logo
6:30 am - 4:07 pmROA  Roanoke-DSM Des Moines
10h 37m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
8:00 am - 1:26 pmDSM  Des Moines-ROA Roanoke
4h 26m1 stop Chicago O'Hare Intl
$344United Airlines
Tue, Oct 27 - Tue, Nov 3
United Airlines Logo
10:26 am - 5:27 pmROA  Roanoke-DSM Des Moines
8h 01m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
9:55 am - 7:07 pmDSM  Des Moines-ROA Roanoke
8h 12m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$349United Airlines
Tue, Oct 27 - Tue, Nov 3
American Airlines Logo
4:11 pm - 12:33 amROA  Roanoke-DSM Des Moines
9h 22m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
7:14 am - 5:44 pmDSM  Des Moines-ROA Roanoke
9h 30m2 stops Chicago O'Hare Intl Charlotte Douglas
$425American Airlines
Fri, Dec 4 - Sun, Dec 6
United Airlines Logo
10:25 am - 2:26 pmROA  Roanoke-DSM Des Moines
5h 01m1 stop Chicago O'Hare Intl
United Airlines Logo
3:20 pm - 9:04 pmDSM  Des Moines-ROA Roanoke
4h 44m1 stop Chicago O'Hare Intl
$439United Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
10:35 am - 5:12 pmROA  Roanoke-DSM Des Moines
7h 37m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
3:20 pm - 9:04 pmDSM  Des Moines-ROA Roanoke
4h 44m1 stop Chicago O'Hare Intl
$444United Airlines
Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
6:10 pm - 11:58 pmROA  Roanoke-DSM Des Moines
6h 48m1 stop Charlotte Douglas
American Airlines Logo
6:05 am - 1:48 pmDSM  Des Moines-ROA Roanoke
6h 43m1 stop Philadelphia
$603American Airlines
Fri, Oct 16 - Fri, Oct 23
American Airlines Logo
6:10 pm - 11:58 pmROA  Roanoke-DSM Des Moines
6h 48m1 stop Charlotte Douglas
American Airlines Logo
6:05 am - 1:48 pmDSM  Des Moines-ROA Roanoke
6h 43m1 stop Philadelphia
$651American Airlines
Fri, Oct 16 - Fri, Oct 23

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United Airlines flights from Roanoke to Des Moines

Our best United Airlines deals on Roanoke to Des Moines flight tickets
United Airlines
Oct 27
ROA5:51 pmRoanoke
5h 04m
1 stop
DSM9:55 pmDes Moines
Nov 3
DSM8:00 amDes Moines
4h 26m
1 stop
ROA1:26 pmRoanoke
$339
United Airlines
Oct 27
ROA6:30 amRoanoke
10h 37m
2 stops
DSM4:07 pmDes Moines
Nov 3
DSM8:00 amDes Moines
4h 26m
1 stop
ROA1:26 pmRoanoke
$344
United Airlines
Oct 27
ROA10:26 amRoanoke
8h 01m
2 stops
DSM5:27 pmDes Moines
Nov 3
DSM9:55 amDes Moines
8h 12m
2 stops
ROA7:07 pmRoanoke
$349

American Airlines flights from Roanoke to Des Moines

Our best American Airlines deals on Roanoke to Des Moines flight tickets
American Airlines
Dec 4
ROA4:11 pmRoanoke
9h 22m
2 stops
DSM12:33 amDes Moines
Dec 6
DSM7:14 amDes Moines
9h 30m
2 stops
ROA5:44 pmRoanoke
$425
American Airlines
Oct 16
ROA6:10 pmRoanoke
6h 48m
1 stop
DSM11:58 pmDes Moines
Oct 23
DSM6:05 amDes Moines
6h 43m
1 stop
ROA1:48 pmRoanoke
$603
American Airlines
Oct 16
ROA6:10 pmRoanoke
6h 48m
1 stop
DSM11:58 pmDes Moines
Oct 23
DSM6:05 amDes Moines
6h 43m
1 stop
ROA1:48 pmRoanoke
$651

momondo Fare Finder

 
Use the filters below to find and compare flights from Roanoke to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/4

6:00 am-10:49 am

1 stop5h 49m

Des Moines

Sun 12/6

6:53 pm-12:26 am

1 stop4h 33m

$339
Quickest round-trip

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/27

5:51 pm-9:55 pm

1 stop5h 04m

Des Moines

Tue 11/3

8:00 am-1:26 pm

1 stop4h 26m

$339

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/4

11:05 am-7:01 pm

2 stops8h 56m

Des Moines

Sun 12/6

9:23 am-4:22 pm

1 stop5h 59m

$344

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/27

6:30 am-4:07 pm

2 stops10h 37m

Des Moines

Tue 11/3

8:00 am-1:26 pm

1 stop4h 26m

$344

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/27

10:26 am-5:27 pm

2 stops8h 01m

Des Moines

Tue 11/3

9:55 am-7:07 pm

2 stops8h 12m

$349

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/4

4:11 pm-12:33 am

2 stops9h 22m

Des Moines

Sun 12/6

7:14 am-5:44 pm

2 stops9h 30m

$425

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Sat 12/5

10:25 am-2:26 pm

1 stop5h 01m

Des Moines

Wed 12/9

3:20 pm-9:04 pm

1 stop4h 44m

$439

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Sat 12/5

10:35 am-5:12 pm

2 stops7h 37m

Des Moines

Wed 12/9

3:20 pm-9:04 pm

1 stop4h 44m

$444

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 10/16

6:10 pm-11:58 pm

1 stop6h 48m

Des Moines

Fri 10/23

6:05 am-1:48 pm

1 stop6h 43m

$603

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 10/16

6:10 pm-11:58 pm

1 stop6h 48m

Des Moines

Fri 10/23

6:05 am-1:48 pm

1 stop6h 43m

$651

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Des Moines from

How to get the cheapest flight ticket from Roanoke to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then September is your next best option. Flight prices from Roanoke to Des Moines during September average around $348.

When to book flights from Roanoke to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Des Moines (ROA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Des Moines

Best Price Found

$339

Fastest flight time

4h 32m

Direct flights

None
The best flight deal from Roanoke to Des Moines found on momondo in the last 72 hours is $339
The fastest flight from Roanoke to Des Moines takes 4h 32m
There are no direct flights from Roanoke to Des Moines. There are no popular flight routes from Roanoke to Des Moines.
Search flight deals

Frequently asked questions about flying from Roanoke to Des Moines

  • How far is Roanoke to Des Moines by plane?

    The distance between Roanoke and Des Moines is about 787.3 mi. Typically, this will take 4h 32m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to Des Moines Airport?

    Prices for flights from Roanoke Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Des Moines Airport?

  • How old do you have to be to fly from Roanoke Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Roanoke Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Roanoke to Des Moines?

Best airlines flying from Roanoke to Des Moines

Compare and see reviews for airlines that fly from Roanoke to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $318Free CancellationRating
7.0
12,127 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Boone
Johnston
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Roanoke.

I’m not ready to book a flight from Roanoke to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Roanoke and alert you when they change.

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