What is the cheapest airline that flies from Washington, D.C. Reagan-National to South America?

American Airlines, United Airlines, and GOL are the most popular carriers operating from Washington, D.C. Reagan-National to South America

What airlines fly to South America?

American Airlines, LATAM Airlines and Delta are the top three most popular airlines that fly to South America from Washington, D.C. Reagan-National Airport according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

How old do you have to be to fly from Washington, D.C. Reagan-National Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Washington, D.C. Reagan-National Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$142 Cheap Flights from Washington, D.C. Reagan-National Airport to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Washington, D.C. Reagan-National Airport to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:59 am - 3:36 pmDCA Washington, D.C. Reagan-National-CTG Cartagena Rafael Nunez

7h 37m1 stop Miami

4:37 pm - 9:28 amCTG Cartagena Rafael Nunez-DCA Washington, D.C. Reagan-National

16h 51m1 stop Miami

$371American Airlines

Tue, Nov 10 - Tue, Nov 17

8:51 pm - 1:35 pmDCA Washington, D.C. Reagan-National-CTG Cartagena Rafael Nunez

16h 44m1 stop Miami

4:37 pm - 9:28 amCTG Cartagena Rafael Nunez-DCA Washington, D.C. Reagan-National

16h 51m1 stop Miami

$371American Airlines

Fri, Nov 13 - Tue, Nov 17

6:00 am - 11:37 amDCA Washington, D.C. Reagan-National-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:37 pm - 11:42 pmCTG Cartagena Rafael Nunez-DCA Washington, D.C. Reagan-National

10h 05m1 stop Fort Lauderdale

$374JetBlue

Sat, Oct 17 - Fri, Oct 23

6:00 am - 11:37 amDCA Washington, D.C. Reagan-National-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:44 pm - 11:24 pmCTG Cartagena Rafael Nunez-DCA Washington, D.C. Reagan-National

9h 40m1 stop Fort Lauderdale

$375JetBlue

Sat, Oct 24 - Sat, Oct 31

8:15 am - 10:10 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

13h 55m1 stop Houston George Bush Intcntl

10:40 am - 11:57 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

13h 17m1 stop Houston George Bush Intcntl

$399United Airlines

Mon, Nov 2 - Wed, Nov 11

12:40 pm - 10:15 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

9h 35m1 stop Houston George Bush Intcntl

10:45 am - 8:35 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

9h 50m1 stop Houston George Bush Intcntl

$399United Airlines

Sun, Feb 21 - Thu, Feb 25

7:59 pm - 2:09 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

18h 10m1 stop Miami

7:00 am - 9:30 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

14h 30m2 stops Miami New York LaGuardia

$426GOL

Mon, Feb 1 - Sat, Feb 27

6:59 am - 10:50 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

15h 51m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

5:20 am - 11:46 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

18h 26m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$443LATAM Airlines

Wed, Nov 11 - Wed, Nov 25

6:30 pm - 5:00 amDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

10h 30m1 stop Atlanta Hartsfield-Jackson

12:05 am - 4:31 pmLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

16h 26m1 stop New York John F Kennedy Intl

$516LATAM Airlines

Mon, Nov 16 - Tue, Dec 8

2:56 pm - 9:55 amDCA Washington, D.C. Reagan-National-GIG Rio de Janeiro–Galeão Intl

17h 59m1 stop New York John F Kennedy Intl

9:55 pm - 10:02 amGIG Rio de Janeiro–Galeão Intl-DCA Washington, D.C. Reagan-National

13h 07m1 stop New York John F Kennedy Intl

$620GOL

Mon, Oct 5 - Wed, Oct 21

Cheap last minute flights

Enter your travel dates to find the best prices.

10:00 am - 8:15 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

11h 15m1 stop Miami

1:50 pm - 9:05 amMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

18h 15m1 stop Miami

$433American Airlines

Sat, Sep 19 - Tue, Oct 20

1:44 pm - 8:15 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

7h 31m1 stop Miami

6:00 am - 6:48 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

11h 48m2 stops Miami New York LaGuardia

$438American Airlines

Sat, Sep 19 - Tue, Oct 20

7:05 am - 9:30 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

15h 25m2 stops Orlando Bogotá El Dorado

6:25 am - 10:09 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

14h 44m2 stops Bogotá El Dorado Orlando

$457Multiple Airlines

Sat, Sep 19 - Tue, Oct 20

7:05 am - 9:30 pmDCA Washington, D.C. Reagan-National-MDE Medellín Jose Maria Cordova Intl

15h 25m2 stops Orlando Bogotá El Dorado

6:25 am - 10:09 pmMDE Medellín Jose Maria Cordova Intl-DCA Washington, D.C. Reagan-National

14h 44m2 stops Bogotá El Dorado Orlando

$477Multiple Airlines

Sat, Sep 19 - Tue, Oct 20

6:00 am - 11:00 pmDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

18h 00m1 stop Houston George Bush Intcntl

12:55 am - 4:04 pmLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

14h 09m1 stop Houston George Bush Intcntl

$577United Airlines

Sun, Sep 20 - Tue, Sep 22

6:00 am - 11:00 pmDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

18h 00m1 stop Houston George Bush Intcntl

11:05 pm - 11:59 amLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

11h 54m1 stop Newark

$577United Airlines

Sun, Sep 20 - Thu, Sep 24

6:00 am - 9:35 pmDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

16h 35m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

12:05 pm - 9:10 amLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

20h 05m1 stop Atlanta Hartsfield-Jackson

$605Delta

Tue, Sep 22 - Fri, Oct 16

12:26 pm - 9:55 pmDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

10h 29m1 stop Atlanta Hartsfield-Jackson

12:05 am - 4:37 pmLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

15h 32m1 stop New York John F Kennedy Intl

$605Delta

Tue, Sep 22 - Thu, Oct 15

8:50 pm - 1:40 pmDCA Washington, D.C. Reagan-National-BOG Bogotá El Dorado

17h 50m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 9:10 amBOG Bogotá El Dorado-DCA Washington, D.C. Reagan-National

17h 15m1 stop Atlanta Hartsfield-Jackson

$609LATAM Airlines

Wed, Sep 23 - Wed, Oct 7

6:59 am - 9:35 pmDCA Washington, D.C. Reagan-National-LIM Lima J Chavez Intl

15h 36m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

12:05 pm - 10:09 amLIM Lima J Chavez Intl-DCA Washington, D.C. Reagan-National

21h 04m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl

$610LATAM Airlines

Tue, Sep 22 - Wed, Oct 14

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LATAM Airlines flights from Washington, D.C. Reagan-National Airport to South America

Our best LATAM Airlines deals on Washington, D.C. Reagan-National Airport to South America flight tickets

LATAM Airlines

Nov 11

DCA6:59 amWashington, D.C. Reagan-National

15h 51m

2 stops

MDE10:50 pmMedellín Jose Maria Cordova Intl

Nov 25

MDE5:20 amMedellín Jose Maria Cordova Intl

18h 26m

2 stops

DCA11:46 pmWashington, D.C. Reagan-National

$443

LATAM Airlines

Sep 19

DCA7:00 amWashington, D.C. Reagan-National

16h 35m

2 stops

MDE10:35 pmMedellín Jose Maria Cordova Intl

Sep 20

MDE6:25 amMedellín Jose Maria Cordova Intl

14h 42m

2 stops

DCA10:07 pmWashington, D.C. Reagan-National

$500

LATAM Airlines

Oct 18

DCA10:10 amWashington, D.C. Reagan-National

13h 25m

2 stops

MDE10:35 pmMedellín Jose Maria Cordova Intl

Oct 28

MDE5:05 amMedellín Jose Maria Cordova Intl

12h 22m

2 stops

DCA6:27 pmWashington, D.C. Reagan-National

$510

Delta flights from Washington, D.C. Reagan-National Airport to South America

Our best Delta deals on Washington, D.C. Reagan-National Airport to South America flight tickets

Delta

Jan 24

DCA6:00 amWashington, D.C. Reagan-National

12h 05m

2 stops

MDE6:05 pmMedellín Jose Maria Cordova Intl

Jan 29

MDE5:35 amMedellín Jose Maria Cordova Intl

16h 27m

2 stops

DCA10:02 pmWashington, D.C. Reagan-National

$431

Delta

Jan 23

DCA8:00 amWashington, D.C. Reagan-National

14h 05m

2 stops

MDE10:05 pmMedellín Jose Maria Cordova Intl

Jan 29

MDE5:35 amMedellín Jose Maria Cordova Intl

16h 27m

2 stops

DCA10:02 pmWashington, D.C. Reagan-National

$561

Delta

Nov 3

DCA1:45 pmWashington, D.C. Reagan-National

15h 15m

1 stop

LIM5:00 amLima J Chavez Intl

Nov 8

LIM11:40 pmLima J Chavez Intl

20h 00m

1 stop

DCA7:40 pmWashington, D.C. Reagan-National

$568

momondo Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Washington, D.C.Cartagena

DCA Washington, D.C. Reagan-National - CTG Cartagena Rafael Nunez

DCACTG

Washington, D.C. Reagan-National

Tue 11/10

7:59 am-3:36 pm

1 stop7h 37m

Cartagena Rafael Nunez

Tue 11/17

4:37 pm-9:28 am

1 stop16h 51m

$371

Washington, D.C.Cartagena

DCA Washington, D.C. Reagan-National - CTG Cartagena Rafael Nunez

DCACTG

Washington, D.C. Reagan-National

Fri 11/13

8:51 pm-1:35 pm

1 stop16h 44m

Cartagena Rafael Nunez

Tue 11/17

4:37 pm-9:28 am

1 stop16h 51m

$371

Washington, D.C.Cartagena

DCA Washington, D.C. Reagan-National - CTG Cartagena Rafael Nunez

DCACTG

Washington, D.C. Reagan-National

Sat 10/17

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Fri 10/23

12:37 pm-11:42 pm

1 stop10h 05m

$374

Quickest round-trip

Washington, D.C.Cartagena

DCA Washington, D.C. Reagan-National - CTG Cartagena Rafael Nunez

DCACTG

Washington, D.C. Reagan-National

Sat 10/24

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Sat 10/31

12:44 pm-11:24 pm

1 stop9h 40m

$375

Washington, D.C.Medellín

DCA Washington, D.C. Reagan-National - MDE Medellín Jose Maria Cordova Intl

DCAMDE

Washington, D.C. Reagan-National

Mon 11/2

8:15 am-10:10 pm

1 stop13h 55m

Medellín Jose Maria Cordova Intl

Wed 11/11

10:40 am-11:57 pm

1 stop13h 17m

$399

Washington, D.C.Medellín

DCA Washington, D.C. Reagan-National - MDE Medellín Jose Maria Cordova Intl

DCAMDE

Washington, D.C. Reagan-National

Sun 2/21

12:40 pm-10:15 pm

1 stop9h 35m

Medellín Jose Maria Cordova Intl

Thu 2/25

10:45 am-8:35 pm

1 stop9h 50m

$399

Washington, D.C.Medellín

DCA Washington, D.C. Reagan-National - MDE Medellín Jose Maria Cordova Intl

DCAMDE

Washington, D.C. Reagan-National

Mon 2/1

7:59 pm-2:09 pm

1 stop18h 10m

Medellín Jose Maria Cordova Intl

Sat 2/27

7:00 am-9:30 pm

2 stops14h 30m

$426

Washington, D.C.Medellín

DCA Washington, D.C. Reagan-National - MDE Medellín Jose Maria Cordova Intl

DCAMDE

Washington, D.C. Reagan-National

Wed 11/11

6:59 am-10:50 pm

2 stops15h 51m

Medellín Jose Maria Cordova Intl

Wed 11/25

5:20 am-11:46 pm

2 stops18h 26m

$443

Washington, D.C.Lima

DCA Washington, D.C. Reagan-National - LIM Lima J Chavez Intl

DCALIM

Washington, D.C. Reagan-National

Mon 11/16

6:30 pm-5:00 am

1 stop10h 30m

Lima J Chavez Intl

Tue 12/8

12:05 am-4:31 pm

1 stop16h 26m

$516

Washington, D.C.Rio de Janeiro

DCA Washington, D.C. Reagan-National - GIG Rio de Janeiro–Galeão Intl

DCAGIG

Washington, D.C. Reagan-National

Mon 10/5

2:56 pm-9:55 am

1 stop17h 59m

Rio de Janeiro–Galeão Intl

Wed 10/21

9:55 pm-10:02 am

1 stop13h 07m

$620

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from Washington, D.C. Reagan-National Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $543. If you aren’t able to travel during the month of January, then book flights to South America from Washington, D.C. Reagan-National Airport during October instead. Flights to South America in October, while not as cheap as those in January, still average around $545.

How far in advance should I book a flight from Washington, D.C. Reagan-National Airport to South America?

You are more likely to see cheaper flights to South America from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $611 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Washington, D.C. Reagan-National Airport for as low as $383 on momondo.

Can stopping save me money on Washington, D.C. Reagan-National Airport to South America flights?

You could potentially save up to 7% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to South America flight.

Cheap Washington, D.C. Reagan-National Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to South America

Best Price Found	$142
Fastest flight time	6h 37m
Direct flights	None

The best one-way flight to South America from Washington, D.C. Reagan-National Airport in the past 72 hours is $142. The best round-trip flight deal from Washington, D.C. Reagan-National Airport to South America found on momondo in the last 72 hours is $371.

The fastest flight from Washington, D.C. Reagan-National Airport to South America takes 6h 37m

There are no direct flights from Washington, D.C. Reagan-National Airport to South America. There are no popular flight routes from Washington, D.C. Reagan-National Airport to South America.

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Frequently asked questions about flying from Washington, D.C. Reagan-National Airport to South America

When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to South America?
Prices for flights from Washington, D.C. Reagan-National Airport to South America are updated daily.
How many operators does momondo search for flights from Washington, D.C. Reagan-National Airport to South America?
There are 8 operators available for flights from Washington, D.C. Reagan-National Airport to South America as of September 2026.
How old do you have to be to fly from Washington, D.C. Reagan-National Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Washington, D.C. Reagan-National Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Washington, D.C. Reagan-National Airport to South America

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $148	Free Cancellation	Rating 7.8 8,579 reviews	Search Delta flights
Copa Airlines	PriceFrom $205	Free Cancellation	Rating 7.6 1,543 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $285	Free Cancellation	Rating 7.1 12,073 reviews	Search American Airlines flights
JetBlue	PriceFrom $296	Free Cancellation	Rating 7.1 3,035 reviews	Search JetBlue flights
United Airlines	PriceFrom $310	Free Cancellation	Rating 7.4 10,214 reviews	Search United Airlines flights
Avianca	PriceFrom $346	Free Cancellation	Rating 6.5 2,549 reviews	Search Avianca flights
LATAM Airlines	PriceFrom $356	Free Cancellation	Rating 7.4 1,985 reviews	Search LATAM Airlines flights
GOL	PriceFrom $582	Free Cancellation	Rating 7.3 1,304 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to South America?

It is quick and easy to find Washington, D.C. to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Washington, D.C. to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Washington, D.C. with this policy.

How can momondo help me find flights from Washington, D.C. to South America?

Once you have performed a search for Washington, D.C. to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Washington, D.C. to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Washington, D.C.. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

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Popular cities

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Other flights to South America

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Complete your trip

Feeling lucky

Popular cities in South America

Flights to Limafrom $409

Flights to Sao Paulofrom $458

Flights to Buenos Airesfrom $522

Flights to Bogotáfrom $325

Flights to Rio de Janeirofrom $496

Flights to Medellínfrom $289

Flights to Santiagofrom $454

Flights to Cartagenafrom $274

Flights to Quitofrom $440

Flights to Guayaquilfrom $367

Flights to Califrom $306

Flights to Cuscofrom $482

Cheap flights from Washington, D.C. Reagan-National Airport to South America from $142

Find the cheapest flights from Washington, D.C. Reagan-National Airport to South America

Cheap round-trip flights

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LATAM Airlines flights from Washington, D.C. Reagan-National Airport to South America

Our best LATAM Airlines deals on Washington, D.C. Reagan-National Airport to South America flight tickets

Delta flights from Washington, D.C. Reagan-National Airport to South America

Our best Delta deals on Washington, D.C. Reagan-National Airport to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to South America

What is the cheapest month to fly to South America?

How far in advance should I book a flight from Washington, D.C. Reagan-National Airport to South America?

Can stopping save me money on Washington, D.C. Reagan-National Airport to South America flights?

What is the cheapest airline that flies from Washington, D.C. Reagan-National to South America?

What airlines fly to South America?

Cheap Washington, D.C. Reagan-National Airport to South America flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Washington, D.C. Reagan-National Airport to South America

Best airlines flying from Washington, D.C. Reagan-National Airport to South America

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to South America with momondo

Why use momondo?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo

Washington, D.C. Reagan-National Airport flight routes

According to popular flight searches on momondo this year

South America flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to South America

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to South America

List of cabin classes available on flights landing in South America. Availability may vary depending on flight origin and airline.

Complete your trip to South America

Explore popular destinations other users love

According to popular flight searches on momondo this year