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Cheap flights from Portland, Maine to Medford from $250

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Medford departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Portland, Maine to Medford

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:57 am - 11:04 pm
PWM
-
MFR
14h 07m
2 stops
American Airlines Logo
5:20 am - 10:46 pm
MFR
-
PWM
14h 26m
2 stops
$490American Airlines
Sat, May 2 - Sat, May 9
United Airlines Logo
9:40 am - 9:31 pm
PWM
-
MFR
14h 51m
2 stops
United Airlines Logo
5:00 am - 3:41 pm
MFR
-
PWM
7h 41m
1 stop
$534United Airlines
Sat, May 2 - Sat, May 9
American Airlines Logo
10:50 am - 11:04 pm
PWM
-
MFR
15h 14m
2 stops
American Airlines Logo
5:20 am - 10:46 pm
MFR
-
PWM
14h 26m
2 stops
$535American Airlines
Sat, May 2 - Sat, May 9
Delta Logo
6:30 am - 11:15 pm
PWM
-
MFR
19h 45m
2 stops
Delta Logo
5:29 pm - 2:13 pm
MFR
-
PWM
17h 44m
2 stops
$547Delta
Thu, Jul 9 - Tue, Jul 21
Delta Logo
12:46 pm - 11:20 pm
PWM
-
MFR
13h 34m
2 stops
Delta Logo
6:15 am - 12:43 am
MFR
-
PWM
15h 28m
2 stops
$548Delta
Sat, May 2 - Sat, May 9
American Airlines Logo
7:22 am - 7:20 pm
PWM
-
MFR
14h 58m
2 stops
American Airlines Logo
5:20 am - 6:53 pm
MFR
-
PWM
10h 33m
2 stops
$553American Airlines
Tue, Aug 25 - Sun, Aug 30
Delta Logo
12:46 pm - 11:20 pm
PWM
-
MFR
13h 34m
2 stops
Delta Logo
6:15 am - 12:43 am
MFR
-
PWM
15h 28m
2 stops
$557Delta
Sat, May 2 - Sat, May 9
United Airlines Logo
9:40 am - 9:31 pm
PWM
-
MFR
14h 51m
2 stops
United Airlines Logo
2:07 pm - 10:18 am
MFR
-
PWM
17h 11m
3 stops
$617United Airlines
Sat, May 2 - Sat, May 9
United Airlines Logo
5:30 am - 5:55 pm
PWM
-
MFR
15h 25m
2 stops
United Airlines Logo
2:07 pm - 10:28 am
MFR
-
PWM
17h 21m
3 stops
$633United Airlines
Sat, May 2 - Sat, May 9
Delta Logo
6:30 am - 11:13 pm
PWM
-
MFR
19h 43m
2 stops
Delta Logo
5:29 pm - 2:13 pm
MFR
-
PWM
17h 44m
2 stops
$638Delta
Sat, Jul 11 - Tue, Jul 21

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American Airlines flights from Portland, Maine to Medford

Our best American Airlines deals on Portland, Maine to Medford flight tickets
American Airlines
May 2
PWM11:57 amPortland
14h 07m
2 stops
MFR11:04 pmMedford
May 9
MFR5:20 amMedford
14h 26m
2 stops
PWM10:46 pmPortland
$490
American Airlines
May 2
PWM10:50 amPortland
15h 14m
2 stops
MFR11:04 pmMedford
May 9
MFR5:20 amMedford
14h 26m
2 stops
PWM10:46 pmPortland
$535
American Airlines
Aug 25
PWM7:22 amPortland
14h 58m
2 stops
MFR7:20 pmMedford
Aug 30
MFR5:20 amMedford
10h 33m
2 stops
PWM6:53 pmPortland
$553

Delta flights from Portland, Maine to Medford

Our best Delta deals on Portland, Maine to Medford flight tickets
Delta
Jul 9
PWM6:30 amPortland
19h 45m
2 stops
MFR11:15 pmMedford
Jul 21
MFR5:29 pmMedford
17h 44m
2 stops
PWM2:13 pmPortland
$547
Delta
May 2
PWM12:46 pmPortland
13h 34m
2 stops
MFR11:20 pmMedford
May 9
MFR6:15 amMedford
15h 28m
2 stops
PWM12:43 amPortland
$548
Delta
May 2
PWM12:46 pmPortland
13h 34m
2 stops
MFR11:20 pmMedford
May 9
MFR6:15 amMedford
15h 28m
2 stops
PWM12:43 amPortland
$557

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 20, 2026.
Use the filters below to find and compare flights from Portland, Maine to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

11:57 am-11:04 pm

2 stops14h 07m

Medford

Sat 5/9

5:20 am-10:46 pm

2 stops14h 26m

$490
Quickest round-trip

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

9:40 am-9:31 pm

2 stops14h 51m

Medford

Sat 5/9

5:00 am-3:41 pm

1 stop7h 41m

$534

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

10:50 am-11:04 pm

2 stops15h 14m

Medford

Sat 5/9

5:20 am-10:46 pm

2 stops14h 26m

$535

PortlandMedford

PWM - MFR

PWMMFR

Portland

Thu 7/9

6:30 am-11:15 pm

2 stops19h 45m

Medford

Tue 7/21

5:29 pm-2:13 pm

2 stops17h 44m

$547

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

12:46 pm-11:20 pm

2 stops13h 34m

Medford

Sat 5/9

6:15 am-12:43 am

2 stops15h 28m

$548

PortlandMedford

PWM - MFR

PWMMFR

Portland

Tue 8/25

7:22 am-7:20 pm

2 stops14h 58m

Medford

Sun 8/30

5:20 am-6:53 pm

2 stops10h 33m

$553

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

12:46 pm-11:20 pm

2 stops13h 34m

Medford

Sat 5/9

6:15 am-12:43 am

2 stops15h 28m

$557

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

9:40 am-9:31 pm

2 stops14h 51m

Medford

Sat 5/9

2:07 pm-10:18 am

3 stops17h 11m

$617

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 5/2

5:30 am-5:55 pm

2 stops15h 25m

Medford

Sat 5/9

2:07 pm-10:28 am

3 stops17h 21m

$633

PortlandMedford

PWM - MFR

PWMMFR

Portland

Sat 7/11

6:30 am-11:13 pm

2 stops19h 43m

Medford

Tue 7/21

5:29 pm-2:13 pm

2 stops17h 44m

$638

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Medford from

How to get the cheapest flight ticket from Portland, Maine to Medford

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Portland, Maine to Medford flights?

You could potentially save up to 4% on your flight if you consider stops on a Portland, Maine to Medford flight.

When to book flights from Portland, Maine to Medford

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Medford according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Medford (PWM to MFR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Medford

Fastest flight time

10h 45m

Direct flights

None
The fastest flight from Portland, Maine to Medford takes 10h 45m
There are no direct flights from Portland, Maine to Medford. There are no popular flight routes from Portland, Maine to Medford.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Medford

  • How far is Portland to Medford by plane?

    There are 2613.6 mi between Portland and Medford. 10h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Medford Airport?

    Prices for flights from Portland Airport to Medford Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Portland Airport to Medford Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Medford Airport.

  • What documentation or ID do you need to fly to Medford Airport?

    The travel and health documents required for your trip to Medford Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Medford Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Ashland
Yreka
Canyonville

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Medford?

It is quick and easy to find Portland to Medford flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Medford that suits you.

Can I find flights from Portland to Medford with flexible booking policies on momondo?

momondo does allow users to show only those flights to Medford from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Medford?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Medford.

I’m not ready to book a flight from Portland to Medford right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Portland to Medford now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Medford and let you know when they change.

An easier way to manage your Medford trip

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Wed 5/20
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