How many flights depart from Panama City to Santiago on average per day?

As of January 2026, 9 flights take off from Panama City and land in Santiago each day. The most common flight departure time for this route is 9:00PM, with 65% of daily flights taking off in the evening.

How often are flights from Panama City to Santiago delayed?

Historically, on average around 5% of flights between Panama City and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 140 minutes.

Which airline has the best punctuality record on Panama City to Santiago flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

What is the cheapest airline that flies from Panama City Tocumen Intl to Santiago Arturo Merino Benitez?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Santiago Arturo Merino Benitez

How many flights depart from Panama City to Santiago on average per week?

The number of flights available between Panama City and Santiago is 63 per week as of January 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.

What day of the week experiences the fewest flight delays on this route?

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

What is the most punctual flight time for Panama City to Santiago flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

There are 2 operators available for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport as of January 2026.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$282 Cheap Flights from Panama City to Santiago in 2026

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:50 pm - 3:20 pm

PTY

SCL

19h 30m

1 stop

2:30 pm - 12:45 am

SCL

PTY

11h 15m

1 stop

$551Avianca

Tue, Feb 17 - Wed, Apr 15

5:25 pm - 5:15 am

PTY

SCL

9h 50m

1 stop

11:55 pm - 10:10 am

SCL

PTY

11h 15m

1 stop

$561Avianca

Wed, Apr 1 - Thu, Apr 30

3:20 am - 2:25 pm

PTY

SCL

9h 05m

1 stop

11:55 pm - 4:30 pm

SCL

PTY

17h 35m

1 stop

$562Avianca

Wed, Apr 1 - Wed, Apr 15

11:48 am - 8:20 pm

PTY

SCL

6h 32mnonstop

5:21 am - 10:03 am

SCL

PTY

6h 42mnonstop

$572Copa Airlines

Wed, Mar 11 - Mon, Mar 16

3:20 am - 2:25 pm

PTY

SCL

9h 05m

1 stop

2:30 pm - 12:10 am

SCL

PTY

10h 40m

1 stop

$580Avianca

Sun, Mar 29 - Tue, Apr 28

11:05 am - 1:09 am

PTY

SCL

12h 04m

2 stops

2:30 pm - 12:45 am

SCL

PTY

11h 15m

1 stop

$583Multiple Airlines

Fri, Apr 3 - Fri, May 1

3:20 am - 2:25 pm

PTY

SCL

9h 05m

1 stop

11:55 pm - 10:10 am

SCL

PTY

11h 15m

1 stop

$585Avianca

Sat, Mar 28 - Sun, May 3

3:51 pm - 12:26 am

PTY

SCL

6h 35mnonstop

11:25 am - 5:11 pm

SCL

PTY

6h 46mnonstop

$588Copa Airlines

Wed, Apr 1 - Fri, Apr 10

6:45 pm - 2:20 am

PTY

SCL

6h 35mnonstop

2:22 am - 8:16 am

SCL

PTY

6h 54mnonstop

$594Copa Airlines

Fri, May 8 - Tue, May 12

2:55 pm - 5:30 am

PTY

SCL

12h 35m

1 stop

7:25 am - 4:55 pm

SCL

PTY

11h 30m

1 stop

$604Avianca

Fri, Feb 13 - Sun, Feb 22

Avianca flights from Panama City to Santiago

Our best Avianca deals on Panama City to Santiago flight tickets

Avianca

Feb 17

PTY5:50 pmPanama City Tocumen Intl

19h 30m

1 stop

SCL3:20 pmSantiago Arturo Merino Benitez

Apr 15

SCL2:30 pmSantiago Arturo Merino Benitez

11h 15m

1 stop

PTY12:45 amPanama City Tocumen Intl

$551

Avianca

Apr 1

PTY5:25 pmPanama City Tocumen Intl

9h 50m

1 stop

SCL5:15 amSantiago Arturo Merino Benitez

Apr 30

SCL11:55 pmSantiago Arturo Merino Benitez

11h 15m

1 stop

PTY10:10 amPanama City Tocumen Intl

$561

Avianca

Apr 1

PTY3:20 amPanama City Tocumen Intl

9h 05m

1 stop

SCL2:25 pmSantiago Arturo Merino Benitez

Apr 15

SCL11:55 pmSantiago Arturo Merino Benitez

17h 35m

1 stop

PTY4:30 pmPanama City Tocumen Intl

$562

Copa Airlines flights from Panama City to Santiago

Our best Copa Airlines deals on Panama City to Santiago flight tickets

Copa Airlines

Mar 11

PTY11:48 amPanama City Tocumen Intl

6h 32m

SCL8:20 pmSantiago Arturo Merino Benitez

Mar 16

SCL5:21 amSantiago Arturo Merino Benitez

6h 42m

PTY10:03 amPanama City Tocumen Intl

$572

Copa Airlines

Apr 1

PTY3:51 pmPanama City Tocumen Intl

6h 35m

SCL12:26 amSantiago Arturo Merino Benitez

Apr 10

SCL11:25 amSantiago Arturo Merino Benitez

6h 46m

PTY5:11 pmPanama City Tocumen Intl

$588

Copa Airlines

May 8

PTY6:45 pmPanama City Tocumen Intl

6h 35m

SCL2:20 amSantiago Arturo Merino Benitez

May 12

SCL2:22 amSantiago Arturo Merino Benitez

6h 54m

PTY8:16 amPanama City Tocumen Intl

$594

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Tue 2/17

5:50 pm-3:20 pm

1 stop19h 30m

Santiago Arturo Merino Benitez

Wed 4/15

2:30 pm-12:45 am

1 stop11h 15m

$551

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 4/1

5:25 pm-5:15 am

1 stop9h 50m

Santiago Arturo Merino Benitez

Thu 4/30

11:55 pm-10:10 am

1 stop11h 15m

$561

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 4/1

3:20 am-2:25 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Wed 4/15

11:55 pm-4:30 pm

1 stop17h 35m

$562

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 3/11

11:48 am-8:20 pm

Nonstop6h 32m

Santiago Arturo Merino Benitez

Mon 3/16

5:21 am-10:03 am

Nonstop6h 42m

$572

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sun 3/29

3:20 am-2:25 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Tue 4/28

2:30 pm-12:10 am

1 stop10h 40m

$580

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Fri 4/3

11:05 am-1:09 am

2 stops12h 04m

Santiago Arturo Merino Benitez

Fri 5/1

2:30 pm-12:45 am

1 stop11h 15m

$583

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sat 3/28

3:20 am-2:25 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Sun 5/3

11:55 pm-10:10 am

1 stop11h 15m

$585

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 4/1

3:51 pm-12:26 am

Nonstop6h 35m

Santiago Arturo Merino Benitez

Fri 4/10

11:25 am-5:11 pm

Nonstop6h 46m

$588

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Fri 5/8

6:45 pm-2:20 am

Nonstop6h 35m

Santiago Arturo Merino Benitez

Tue 5/12

2:22 am-8:16 am

Nonstop6h 54m

$594

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Fri 2/13

2:55 pm-5:30 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Sun 2/22

7:25 am-4:55 pm

1 stop11h 30m

$604

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Other information

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Panama City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $561. If you don’t want to visit Santiago in April, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $561.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $561. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Friday is $669.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Panama City to Santiago when you can find flight prices for as low as $583. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $656 per ticket.

What is the cheapest Panama City Tocumen Intl to Santiago Arturo Merino Benitez flight route?

Fly from Panama City Tocumen Intl to Santiago Arturo Merino Benitez for the best Panama City Tocumen Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $569 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Panama City for as low as $527 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Santiago flights?

You could potentially save up to 72% on your flight if you consider stops on a Panama City to Santiago flight.

How have Panama City to Santiago flight prices changed over time?

As of January 2026, prices for Panama City to Santiago flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Santiago (PTY to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santiago

Best Price Found	$1,051
Fastest flight time	6h 32m
Direct flights	Every day
Airports in Santiago	1 airport

The best one-way flight to Santiago from Panama City in the past 72 hours is $1,051. The best round-trip flight deal from Panama City to Santiago found on momondo in the last 72 hours is $572.

The fastest flight from Panama City to Santiago takes 6h 32m

Direct flights go from Panama City to Santiago every day.

There is 1 airport in Santiago. From Panama City there are direct flights to Santiago Arturo Merino Benitez (SCL).

Search flight deals

How far is Panama City Tocumen Intl to Santiago Arturo Merino Benitez by plane?
Santiago Arturo Merino Benitez is 2987.0 mi away from Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 6h 32m.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
There are 2 operators available for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport as of January 2026.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Santiago?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Panama City to Santiago is Boeing 737 MAX 9 (41.78% of total bookings). The next most popular plane models are Boeing 737-800 (41.78%) and Boeing 737-900 (16.44%).
What is the most popular airline from Panama City to Santiago?
Based on momondo bookings for flights between Panama City and Santiago, the leading airline is Copa Airlines, making up 75% of the total bookings. Other popular airlines include Avianca with 25%.

Best airlines flying from Panama City to Santiago

Compare and see reviews for airlines that fly from Panama City to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $218	Free Cancellation	Rating 6.6 2,496 reviews		Search Avianca flights
Copa Airlines	PriceFrom $402	Free Cancellation	Rating 7.6 1,557 reviews		Search Copa Airlines flights

Copa Airlines Flights From Panama City to Santiago
Across 42 Copa Airlines flights from Panama City to Santiago this week, the average price was $587, with the best Copa Airlines deals starting from $402 round-trip. 1,559 users have rated Copa Airlines on momondo, with an average score of 7.6/10.

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Panama City to Santiago from $282

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santiago departing on 2/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Panama City to Santiago

What is the cheapest month to fly to Santiago?

What is the cheapest day to depart on your flight to Santiago?

What is the cheapest time of day to depart on your flight to Santiago?

What is the cheapest Panama City Tocumen Intl to Santiago Arturo Merino Benitez flight route?

Fly from Panama City Tocumen Intl to Santiago Arturo Merino Benitez for the best Panama City Tocumen Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

What cabin class options are available on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Santiago flights?

You could potentially save up to 72% on your flight if you consider stops on a Panama City to Santiago flight.

How have Panama City to Santiago flight prices changed over time?

As of January 2026, prices for Panama City to Santiago flights are approximately 21% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Santiago Arturo Merino Benitez?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Santiago Arturo Merino Benitez

How often are flights from Panama City to Santiago delayed?

Historically, on average around 5% of flights between Panama City and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 140 minutes.

What is the most punctual flight time for Panama City to Santiago flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on Panama City to Santiago flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

How many flights depart from Panama City to Santiago on average per day?

As of January 2026, 9 flights take off from Panama City and land in Santiago each day. The most common flight departure time for this route is 9:00PM, with 65% of daily flights taking off in the evening.

How many flights depart from Panama City to Santiago on average per week?

The number of flights available between Panama City and Santiago is 63 per week as of January 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.

When to book flights from Panama City to Santiago

Cheap Panama City to Santiago (PTY to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santiago

Best Price Found

Fastest flight time

Direct flights

Airports in Santiago

How far is Panama City Tocumen Intl to Santiago Arturo Merino Benitez by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

What is the most popular plane model from Panama City to Santiago?

What is the most popular airline from Panama City to Santiago?

Best airlines flying from Panama City to Santiago

Compare and see reviews for airlines that fly from Panama City to Santiago with momondo

Copa Airlines Flights From Panama City to Santiago

Traveling to a place near Santiago?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santiago?

Can I find flights from Panama City to Santiago with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Santiago?

I’m not ready to book a flight from Panama City to Santiago right now. Can momondo alert me if prices change?

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chile

Airports servicing Chile