How many flights depart from Panama City to Santiago on average per day?

As of December 2025, 8 flights take off from Panama City and land in Santiago each day. The most common flight departure time for this route is 9:00PM, with 67% of daily flights taking off in the evening.

What day of the week experiences the fewest flight delays on this route?

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

What is the most punctual flight time for Panama City to Santiago flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

How often are flights from Panama City to Santiago delayed?

Historically, on average around 5% of flights between Panama City and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 142 minutes.

How many flights depart from Panama City to Santiago on average per week?

The number of flights available between Panama City and Santiago is 60 per week as of December 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

Which airline has the best punctuality record on Panama City to Santiago flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

What is the cheapest airline that flies from Panama City Tocumen Intl to Santiago Arturo Merino Benitez?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Santiago Arturo Merino Benitez

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

There are 2 operators available for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport as of December 2025.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$283 Cheap Flights from Panama City to Santiago in 2025/26

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Cheap round-trip flights

Enter your travel dates to find the best prices.

11:48 am - 8:21 pm

PTY

SCL

6h 33mnonstop

5:20 am - 10:03 am

SCL

PTY

6h 43mnonstop

$465Copa Airlines

Sun, Dec 21 - Sat, Feb 21

6:45 pm - 3:20 am

PTY

SCL

6h 35mnonstop

11:25 am - 5:11 pm

SCL

PTY

6h 46mnonstop

$481Copa Airlines

Thu, Apr 2 - Wed, Apr 15

3:51 pm - 12:32 am

PTY

SCL

6h 41mnonstop

5:44 am - 10:35 am

SCL

PTY

6h 51mnonstop

$513Copa Airlines

Sat, Jan 3 - Mon, Feb 9

11:48 am - 8:21 pm

PTY

SCL

6h 33mnonstop

12:28 pm - 5:11 pm

SCL

PTY

6h 43mnonstop

$530Copa Airlines

Sat, Dec 27 - Thu, Jan 15

3:51 pm - 12:32 am

PTY

SCL

6h 41mnonstop

1:16 am - 6:00 am

SCL

PTY

6h 44mnonstop

$546Copa Airlines

Mon, Jan 12 - Fri, Jan 16

9:45 am - 12:30 am

PTY

SCL

12h 45m1 stop

4:25 pm - 1:00 am

SCL

PTY

10h 35m1 stop

$549Avianca

Sun, Jan 25 - Thu, Feb 5

2:55 am - 3:20 pm

PTY

SCL

10h 25m1 stop

7:25 am - 4:55 pm

SCL

PTY

11h 30m1 stop

$551Avianca

Fri, Jan 9 - Sat, Jan 24

10:05 pm - 1:25 pm

PTY

SCL

14h 20m1 stop

11:55 pm - 4:30 pm

SCL

PTY

17h 35m1 stop

$561Avianca

Mon, May 4 - Tue, May 12

6:45 pm - 2:20 am

PTY

SCL

6h 35mnonstop

4:09 am - 10:03 am

SCL

PTY

6h 54mnonstop

$562Copa Airlines

Mon, May 4 - Tue, May 12

3:08 pm - 10:43 pm

PTY

SCL

6h 35mnonstop

12:38 am - 6:32 am

SCL

PTY

6h 54mnonstop

$572Copa Airlines

Thu, Apr 16 - Tue, Jun 9

Avianca flights from Panama City to Santiago

Our best Avianca deals on Panama City to Santiago flight tickets

Avianca

Jan 25

PTY9:45 amPanama City Tocumen Intl

12h 45m

1 stop

SCL12:30 amSantiago Arturo Merino Benitez

Feb 5

SCL4:25 pmSantiago Arturo Merino Benitez

10h 35m

1 stop

PTY1:00 amPanama City Tocumen Intl

$549

Find similar

Avianca

Jan 9

PTY2:55 amPanama City Tocumen Intl

10h 25m

1 stop

SCL3:20 pmSantiago Arturo Merino Benitez

Jan 24

SCL7:25 amSantiago Arturo Merino Benitez

11h 30m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$551

Find similar

Avianca

Feb 11

PTY2:55 amPanama City Tocumen Intl

10h 25m

1 stop

SCL3:20 pmSantiago Arturo Merino Benitez

Feb 23

SCL7:25 amSantiago Arturo Merino Benitez

11h 30m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$561

Find similar

Copa Airlines flights from Panama City to Santiago

Our best Copa Airlines deals on Panama City to Santiago flight tickets

Copa Airlines

Dec 21

PTY3:08 pmPanama City Tocumen Intl

6h 33m

SCL11:41 pmSantiago Arturo Merino Benitez

Dec 25

SCL12:20 pmSantiago Arturo Merino Benitez

6h 51m

PTY5:11 pmPanama City Tocumen Intl

$465

Find similar

Copa Airlines

Apr 2

PTY6:45 pmPanama City Tocumen Intl

6h 35m

SCL3:20 amSantiago Arturo Merino Benitez

Apr 15

SCL11:25 amSantiago Arturo Merino Benitez

6h 46m

PTY5:11 pmPanama City Tocumen Intl

$481

Find similar

Copa Airlines

Jan 3

PTY3:51 pmPanama City Tocumen Intl

6h 41m

SCL12:32 amSantiago Arturo Merino Benitez

Feb 9

SCL5:44 amSantiago Arturo Merino Benitez

6h 51m

PTY10:35 amPanama City Tocumen Intl

$513

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sun 12/21

11:48 am-8:21 pm

Nonstop6h 33m

Santiago Arturo Merino Benitez

Sat 2/21

5:20 am-10:03 am

Nonstop6h 43m

$465

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Thu 4/2

6:45 pm-3:20 am

Nonstop6h 35m

Santiago Arturo Merino Benitez

Wed 4/15

11:25 am-5:11 pm

Nonstop6h 46m

$481

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sat 1/3

3:51 pm-12:32 am

Nonstop6h 41m

Santiago Arturo Merino Benitez

Mon 2/9

5:44 am-10:35 am

Nonstop6h 51m

$513

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sat 12/27

11:48 am-8:21 pm

Nonstop6h 33m

Santiago Arturo Merino Benitez

Thu 1/15

12:28 pm-5:11 pm

Nonstop6h 43m

$530

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Mon 1/12

3:51 pm-12:32 am

Nonstop6h 41m

Santiago Arturo Merino Benitez

Fri 1/16

1:16 am-6:00 am

Nonstop6h 44m

$546

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Sun 1/25

9:45 am-12:30 am

1 stop12h 45m

Santiago Arturo Merino Benitez

Thu 2/5

4:25 pm-1:00 am

1 stop10h 35m

$549

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Fri 1/9

2:55 am-3:20 pm

1 stop10h 25m

Santiago Arturo Merino Benitez

Sat 1/24

7:25 am-4:55 pm

1 stop11h 30m

$551

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Mon 5/4

10:05 pm-1:25 pm

1 stop14h 20m

Santiago Arturo Merino Benitez

Tue 5/12

11:55 pm-4:30 pm

1 stop17h 35m

$561

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Mon 5/4

6:45 pm-2:20 am

Nonstop6h 35m

Santiago Arturo Merino Benitez

Tue 5/12

4:09 am-10:03 am

Nonstop6h 54m

$562

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Thu 4/16

3:08 pm-10:43 pm

Nonstop6h 35m

Santiago Arturo Merino Benitez

Tue 6/9

12:38 am-6:32 am

Nonstop6h 54m

$572

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How to get the cheapest flight ticket from Panama City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Other information

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Panama City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $557. If you don’t want to visit Santiago in June, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $560.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Thursday when prices can be found for as low as $561. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $706.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Panama City to Santiago when you can find flight prices for as low as $621. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $669 per ticket.

What is the cheapest Panama City Tocumen Intl to Santiago Arturo Merino Benitez flight route?

Fly from Panama City Tocumen Intl to Santiago Arturo Merino Benitez for the best Panama City Tocumen Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $573 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Panama City for as low as $512 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Santiago flights?

You could potentially save up to 71% on your flight if you consider stops on a Panama City to Santiago flight.

How have Panama City to Santiago flight prices changed over time?

As of December 2025, prices for Panama City to Santiago flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Santiago (PTY to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santiago

Best Price Found	$561
Fastest flight time	6h 32m
Direct flights	Every day
Airports in Santiago	1 airport

The best flight deal from Panama City to Santiago found on momondo in the last 72 hours is $561

The fastest flight from Panama City to Santiago takes 6h 32m

Direct flights go from Panama City to Santiago every day.

There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

Search flight deals

How far is Panama City Tocumen Intl to Santiago Arturo Merino Benitez by plane?
Santiago Arturo Merino Benitez is 2987.0 mi away from Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 6h 32m.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
There are 2 operators available for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport as of December 2025.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Santiago?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Panama City to Santiago is Boeing 737 MAX 9 (43.37% of total bookings). The next most popular plane models are Boeing 737-800 (43.37%) and Boeing 737-900 (13.26%).
What is the most popular airline from Panama City to Santiago?
Based on momondo bookings for flights between Panama City and Santiago, the leading airline is Copa Airlines, making up 72% of the total bookings. Other popular airlines include Avianca with 28%.

Best airlines flying from Panama City to Santiago

Compare and see reviews for airlines that fly from Panama City to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $284	Free Cancellation	Rating 6.6 2,479 reviews		Search Avianca flights
Copa Airlines	PriceFrom $481	Free Cancellation	Rating 7.6 1,554 reviews		Search Copa Airlines flights

Copa Airlines Flights From Panama City to Santiago
Across 39 Copa Airlines flights from Panama City to Santiago this week, the average price was $635, with the best Copa Airlines deals starting from $481 round-trip. 1,554 users have rated Copa Airlines on momondo, with an average score of 7.6/10.

Viña del Mar

Santa Cruz

Valparaíso

Valle Nevado

San Fernando

Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Panama City to Santiago from $290

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santiago departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Panama City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

What is the cheapest day to depart on your flight to Santiago?

What is the cheapest time of day to depart on your flight to Santiago?

What is the cheapest Panama City Tocumen Intl to Santiago Arturo Merino Benitez flight route?

Fly from Panama City Tocumen Intl to Santiago Arturo Merino Benitez for the best Panama City Tocumen Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

What cabin class options are available on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Santiago flights?

You could potentially save up to 71% on your flight if you consider stops on a Panama City to Santiago flight.

How have Panama City to Santiago flight prices changed over time?

As of December 2025, prices for Panama City to Santiago flights are approximately 8% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Santiago Arturo Merino Benitez?

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Santiago Arturo Merino Benitez

How often are flights from Panama City to Santiago delayed?

Historically, on average around 5% of flights between Panama City and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 142 minutes.

What is the most punctual flight time for Panama City to Santiago flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on Panama City to Santiago flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

How many flights depart from Panama City to Santiago on average per day?

As of December 2025, 8 flights take off from Panama City and land in Santiago each day. The most common flight departure time for this route is 9:00PM, with 67% of daily flights taking off in the evening.

How many flights depart from Panama City to Santiago on average per week?

The number of flights available between Panama City and Santiago is 60 per week as of December 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

When to book flights from Panama City to Santiago

Cheap Panama City to Santiago (PTY to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santiago

Best Price Found

Fastest flight time

Direct flights

Airports in Santiago

How far is Panama City Tocumen Intl to Santiago Arturo Merino Benitez by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

What is the most popular plane model from Panama City to Santiago?

What is the most popular airline from Panama City to Santiago?

Best airlines flying from Panama City to Santiago

Compare and see reviews for airlines that fly from Panama City to Santiago with momondo

Copa Airlines Flights From Panama City to Santiago

Traveling to a place near Santiago?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santiago?

Can I find flights from Panama City to Santiago with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Santiago?

I’m not ready to book a flight from Panama City to Santiago right now. Can momondo alert me if prices change?

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chile

Airports servicing Chile