What is the cheapest airline that flies from Panama City NW Florida Beaches to South Carolina?

American Airlines, Southwest, and Delta are the most popular carriers operating from Panama City NW Florida Beaches to South Carolina

What airlines fly to South Carolina?

Delta, American Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Panama City, Florida according to our data. Delta is the first choice among our users, with 69% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 3 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?

Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?

There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of September 2025.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$129 Cheap Flights from Panama City to South Carolina in 2025/26

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Find the cheapest flights from Panama City, Florida to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

6:44 am - 11:40 amECP-GSP

3h 56m1 stop

6:24 pm - 10:08 pmGSP-ECP

4h 44m1 stop

$272American Airlines

Find Deal

Thu, Oct 30 - Sat, Nov 1

7:45 am - 1:54 pmECP-GSP

5h 09m1 stop

5:45 am - 8:20 amGSP-ECP

3h 35m1 stop

$292Delta

Find Deal

Thu, Feb 19 - Sun, Feb 22

5:50 pm - 10:37 pmECP-MYR

3h 47m1 stop

12:09 pm - 5:18 pmMYR-ECP

6h 09m1 stop

$292American Airlines

Find Deal

Fri, Dec 5 - Mon, Dec 8

6:00 am - 1:25 pmECP-CHS

6h 25m1 stop

5:25 am - 8:35 amCHS-ECP

4h 10m1 stop

$322Delta

Find Deal

Wed, Nov 19 - Sun, Nov 23

6:17 pm - 11:59 pmECP-CHS

4h 42m1 stop

8:10 am - 12:30 pmCHS-ECP

5h 20m1 stop

$327Delta

Find Deal

Fri, Oct 24 - Mon, Oct 27

3:41 pm - 11:08 pmECP-CHS

6h 27m1 stop

6:00 am - 2:10 pmCHS-ECP

9h 10m2 stops

$332American Airlines

Find Deal

Fri, Oct 24 - Mon, Oct 27

9:29 am - 2:25 pmECP-GSP

3h 56m1 stop

6:35 am - 8:44 amGSP-ECP

3h 09m1 stop

$334Delta

Find Deal

Tue, Oct 7 - Tue, Oct 21

7:35 am - 11:55 amECP-GSP

3h 20m1 stop

10:50 am - 4:45 pmGSP-ECP

6h 55m1 stop

$342Southwest

Find Deal

Thu, Feb 19 - Sun, Feb 22

7:15 am - 7:45 pmECP-MYR

11h 30m2 stops

10:45 am - 7:05 pmMYR-ECP

9h 20m1 stop

$348Southwest

Find Deal

Fri, Dec 5 - Mon, Dec 8

1:55 pm - 10:00 amECP-CHS

19h 05m2 stops

6:02 am - 9:48 pmCHS-ECP

16h 46m2 stops

$1,015United Airlines

Find Deal

Wed, Oct 8 - Sun, Oct 12

Delta flights from Panama City, Florida to South Carolina

Our best Delta deals on Panama City, Florida to South Carolina flight tickets

Delta

Feb 19

ECP7:45 amPanama City NW Florida Beaches

5h 09m

1 stop

GSP1:54 pmGreenville

Feb 22

GSP5:45 amGreenville

3h 35m

1 stop

ECP8:20 amPanama City NW Florida Beaches

$292

Find similar

Delta

Nov 19

ECP6:00 amPanama City NW Florida Beaches

6h 25m

1 stop

CHS1:25 pmCharleston

Nov 23

CHS5:25 amCharleston

4h 10m

1 stop

ECP8:35 amPanama City NW Florida Beaches

$322

Find similar

Delta

Oct 24

ECP6:17 pmPanama City NW Florida Beaches

4h 42m

1 stop

CHS11:59 pmCharleston

Oct 27

CHS8:10 amCharleston

5h 20m

1 stop

ECP12:30 pmPanama City NW Florida Beaches

$327

Find similar

Southwest flights from Panama City, Florida to South Carolina

Our best Southwest deals on Panama City, Florida to South Carolina flight tickets

Southwest

Feb 19

ECP7:35 amPanama City NW Florida Beaches

3h 20m

1 stop

GSP11:55 amGreenville

Feb 22

GSP10:50 amGreenville

6h 55m

1 stop

ECP4:45 pmPanama City NW Florida Beaches

$342

Find similar

Southwest

Dec 5

ECP7:15 amPanama City NW Florida Beaches

11h 30m

2 stops

MYR7:45 pmMyrtle Beach Intl

Dec 8

MYR10:45 amMyrtle Beach Intl

9h 20m

1 stop

ECP7:05 pmPanama City NW Florida Beaches

$348

Find similar

Southwest

Feb 19

ECP7:35 amPanama City NW Florida Beaches

3h 20m

1 stop

GSP11:55 amGreenville

Feb 22

GSP8:30 amGreenville

15h 00m

2 stops

ECP10:30 pmPanama City NW Florida Beaches

$353

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 10/30

6:44 am-11:40 am

1 stop3h 56m

Greenville

Sat 11/1

6:24 pm-10:08 pm

1 stop4h 44m

$272

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 2/19

7:45 am-1:54 pm

1 stop5h 09m

Greenville

Sun 2/22

5:45 am-8:20 am

1 stop3h 35m

$292

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Fri 12/5

5:50 pm-10:37 pm

1 stop3h 47m

Myrtle Beach Intl

Mon 12/8

12:09 pm-5:18 pm

1 stop6h 09m

$292

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 11/19

6:00 am-1:25 pm

1 stop6h 25m

Charleston

Sun 11/23

5:25 am-8:35 am

1 stop4h 10m

$322

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 10/24

6:17 pm-11:59 pm

1 stop4h 42m

Charleston

Mon 10/27

8:10 am-12:30 pm

1 stop5h 20m

$327

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 10/24

3:41 pm-11:08 pm

1 stop6h 27m

Charleston

Mon 10/27

6:00 am-2:10 pm

2 stops9h 10m

$332

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 10/7

9:29 am-2:25 pm

1 stop3h 56m

Greenville

Tue 10/21

6:35 am-8:44 am

1 stop3h 09m

$334

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 2/19

7:35 am-11:55 am

1 stop3h 20m

Greenville

Sun 2/22

10:50 am-4:45 pm

1 stop6h 55m

$342

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Fri 12/5

7:15 am-7:45 pm

2 stops11h 30m

Myrtle Beach Intl

Mon 12/8

10:45 am-7:05 pm

1 stop9h 20m

$348

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 10/8

1:55 pm-10:00 am

2 stops19h 05m

Charleston

Sun 10/12

6:02 am-9:48 pm

2 stops16h 46m

$1,015

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Panama City, Florida is in August. Flight prices, which tend to average around $266, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Panama City, Florida during October instead. Flights to South Carolina in October, while not as cheap as those in August, still average around $276.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $286. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $523.

Cheap Panama City, Florida to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South Carolina

Direct flights	None

There are no direct flights from Panama City, Florida to South Carolina. There are no popular flight routes from Panama City, Florida to South Carolina.

Search flight deals

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?
Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?
There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of September 2025.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama City, Florida to South Carolina

Compare and see reviews for airlines that fly from Panama City, Florida to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $202	Free Cancellation	Rating 7.9 7,973 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

It is quick and easy to find Panama City to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

Flights from Panama City to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to South Carolina?

momondo helps you find the best flight between Panama City and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to South Carolina

Popular cities in South Carolina

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Flights to Orlandofrom $56

Flights to Las Vegasfrom $44

Flights to San Franciscofrom $60

Flights to Washington, D.C.from $56

Flights to Bostonfrom $68

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Flights to Dallasfrom $60

Flights to Seattlefrom $86

Panama City, Florida flight routes

Flights from Panama City NW Florida Beaches to Austin Bergstrom

Flights from Panama City NW Florida Beaches to Houston Hobby

Flights from Panama City NW Florida Beaches to Lambert-St Louis

Flights from Panama City NW Florida Beaches to Washington, D.C. Reagan-National

Flights from Panama City NW Florida Beaches to Baltimore/Washington

Flights from Panama City NW Florida Beaches to Houston George Bush Intcntl

Cheap flights from Panama City, Florida to South Carolina from $129

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Panama City, Florida to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Delta flights from Panama City, Florida to South Carolina

Our best Delta deals on Panama City, Florida to South Carolina flight tickets

Southwest flights from Panama City, Florida to South Carolina

Our best Southwest deals on Panama City, Florida to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Panama City, Florida to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $286. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $523.

What is the cheapest airline that flies from Panama City NW Florida Beaches to South Carolina?

American Airlines, Southwest, and Delta are the most popular carriers operating from Panama City NW Florida Beaches to South Carolina

What airlines fly to South Carolina?

Cheap Panama City, Florida to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South Carolina

Direct flights

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?

How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?

What documentation or ID do you need to fly to South Carolina?

Best airlines flying from Panama City, Florida to South Carolina

Compare and see reviews for airlines that fly from Panama City, Florida to South Carolina with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to South Carolina?

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo