What is the cheapest airline that flies from Panama City NW Florida Beaches to South Carolina?

American Airlines, Delta, and Southwest are the most popular carriers operating from Panama City NW Florida Beaches to South Carolina

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?

Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?

There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of December 2025.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$126 Cheap Flights from Panama City to South Carolina in 2025/26

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Find the cheapest flights from Panama City, Florida to South Carolina

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

12:03 pm - 7:02 pm

ECP

CHS

5h 59m1 stop

6:10 am - 11:33 am

CHS

ECP

6h 23m1 stop

$251American Airlines

Tue, Jan 13 - Tue, Jan 20

6:00 am - 11:48 am

ECP

CHS

4h 48m1 stop

10:25 am - 12:45 pm

CHS

ECP

3h 20m1 stop

$303Delta

Wed, Jan 7 - Tue, Jan 13

12:03 pm - 7:02 pm

ECP

CHS

5h 59m1 stop

7:20 pm - 11:33 am

CHS

ECP

17h 13m2 stops

$305American Airlines

Tue, Jan 13 - Tue, Jan 20

6:03 pm - 11:07 pm

ECP

CHS

4h 04m1 stop

6:00 am - 5:33 pm

CHS

ECP

12h 33m2 stops

$308American Airlines

Wed, Jan 7 - Tue, Jan 13

6:03 pm - 11:36 pm

ECP

GSP

4h 33m1 stop

6:00 am - 11:33 am

GSP

ECP

6h 33m1 stop

$323American Airlines

Tue, Jan 6 - Mon, Jan 12

8:00 am - 3:50 pm

ECP

CHS

6h 50m2 stops

9:05 am - 6:10 pm

CHS

ECP

10h 05m2 stops

$341Southwest

Wed, Jan 7 - Wed, Jan 14

1:01 pm - 9:59 pm

ECP

GSP

7h 58m1 stop

6:50 am - 12:04 pm

GSP

ECP

6h 14m1 stop

$388United Airlines

Sat, Feb 14 - Wed, Feb 18

8:00 am - 3:50 pm

ECP

CHS

6h 50m2 stops

9:05 am - 6:10 pm

CHS

ECP

10h 05m2 stops

$391Southwest

Tue, Jan 6 - Tue, Jan 13

5:14 pm - 11:55 pm

ECP

GSP

5h 41m1 stop

3:05 pm - 7:50 pm

GSP

ECP

5h 45m1 stop

$465Delta

Mon, Jan 5 - Mon, Jan 12

1:01 pm - 9:59 pm

ECP

GSP

7h 58m1 stop

6:30 am - 12:04 pm

GSP

ECP

30h 34m2 stops

$515United Airlines

Sat, Feb 14 - Wed, Feb 18

American Airlines flights from Panama City, Florida to South Carolina

Our best American Airlines deals on Panama City, Florida to South Carolina flight tickets

American Airlines

Jan 13

ECP12:03 pmPanama City NW Florida Beaches

5h 59m

1 stop

CHS7:02 pmCharleston

Jan 20

CHS6:10 amCharleston

6h 23m

1 stop

ECP11:33 amPanama City NW Florida Beaches

$251

Find similar

American Airlines

Jan 13

ECP12:03 pmPanama City NW Florida Beaches

5h 59m

1 stop

CHS7:02 pmCharleston

Jan 20

CHS7:20 pmCharleston

17h 13m

2 stops

ECP11:33 amPanama City NW Florida Beaches

$305

Find similar

American Airlines

Jan 7

ECP6:03 pmPanama City NW Florida Beaches

4h 04m

1 stop

CHS11:07 pmCharleston

Jan 13

CHS6:00 amCharleston

12h 33m

2 stops

ECP5:33 pmPanama City NW Florida Beaches

$308

Find similar

Southwest flights from Panama City, Florida to South Carolina

Our best Southwest deals on Panama City, Florida to South Carolina flight tickets

Southwest

Jan 7

ECP8:00 amPanama City NW Florida Beaches

6h 50m

2 stops

CHS3:50 pmCharleston

Jan 14

CHS9:05 amCharleston

10h 05m

2 stops

ECP6:10 pmPanama City NW Florida Beaches

$341

Find similar

Southwest

Jan 6

ECP8:00 amPanama City NW Florida Beaches

6h 50m

2 stops

CHS3:50 pmCharleston

Jan 13

CHS9:05 amCharleston

10h 05m

2 stops

ECP6:10 pmPanama City NW Florida Beaches

$391

Find similar

Southwest

Jan 5

ECP1:30 pmPanama City NW Florida Beaches

7h 05m

2 stops

GSP9:35 pmGreenville

Jan 12

GSP11:15 amGreenville

7h 55m

1 stop

ECP6:10 pmPanama City NW Florida Beaches

$537

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 1/13

12:03 pm-7:02 pm

1 stop5h 59m

Charleston

Tue 1/20

6:10 am-11:33 am

1 stop6h 23m

$251

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 1/7

6:00 am-11:48 am

1 stop4h 48m

Charleston

Tue 1/13

10:25 am-12:45 pm

1 stop3h 20m

$303

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 1/13

12:03 pm-7:02 pm

1 stop5h 59m

Charleston

Tue 1/20

7:20 pm-11:33 am

2 stops17h 13m

$305

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 1/7

6:03 pm-11:07 pm

1 stop4h 04m

Charleston

Tue 1/13

6:00 am-5:33 pm

2 stops12h 33m

$308

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 1/6

6:03 pm-11:36 pm

1 stop4h 33m

Greenville

Mon 1/12

6:00 am-11:33 am

1 stop6h 33m

$323

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 1/7

8:00 am-3:50 pm

2 stops6h 50m

Charleston

Wed 1/14

9:05 am-6:10 pm

2 stops10h 05m

$341

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

6:50 am-12:04 pm

1 stop6h 14m

$388

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 1/6

8:00 am-3:50 pm

2 stops6h 50m

Charleston

Tue 1/13

9:05 am-6:10 pm

2 stops10h 05m

$391

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 1/5

5:14 pm-11:55 pm

1 stop5h 41m

Greenville

Mon 1/12

3:05 pm-7:50 pm

1 stop5h 45m

$465

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

6:30 am-12:04 pm

2 stops30h 34m

$515

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Panama City, Florida to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Panama City, Florida is in August. Flight prices, which tend to average around $266, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Panama City, Florida during October instead. Flights to South Carolina in October, while not as cheap as those in August, still average around $316.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $286. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $523.

Cheap Panama City, Florida to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South Carolina

Fastest flight time	3h 24m
Direct flights	None

The fastest flight from Panama City, Florida to South Carolina takes 3h 24m

There are no direct flights from Panama City, Florida to South Carolina. There are no popular flight routes from Panama City, Florida to South Carolina.

Search flight deals

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?
Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?
There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of December 2025.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama City, Florida to South Carolina

Compare and see reviews for airlines that fly from Panama City, Florida to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $196	Free Cancellation	Rating 7.9 8,004 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

It is quick and easy to find Panama City to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

Flights from Panama City to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to South Carolina?

momondo helps you find the best flight between Panama City and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Sat 1/17

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Find better results for your trip to South Carolina

Popular cities in South Carolina

Flights to New Yorkfrom $45

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Flights to Chicagofrom $58

Flights to Orlandofrom $49

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Flights to Las Vegasfrom $39

Flights to Washington, D.C.from $58

Flights to Bostonfrom $49

Flights to Atlantafrom $46

Flights to Dallasfrom $51

Flights to Seattlefrom $58

Panama City, Florida flight routes

Flights from Panama City NW Florida Beaches to Washington, D.C. Reagan-National

Flights from Panama City NW Florida Beaches to Houston George Bush Intcntl

Flights from Panama City NW Florida Beaches to Chicago O'Hare Intl

Flights from Panama City NW Florida Beaches to Austin Bergstrom

Flights from Panama City NW Florida Beaches to Dallas/Fort Worth

Flights from Panama City NW Florida Beaches to Atlanta Hartsfield-Jackson

Cheap flights from Panama City, Florida to South Carolina from $126

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Panama City, Florida to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

American Airlines flights from Panama City, Florida to South Carolina

Our best American Airlines deals on Panama City, Florida to South Carolina flight tickets

Southwest flights from Panama City, Florida to South Carolina

Our best Southwest deals on Panama City, Florida to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Panama City, Florida to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $286. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $523.

What is the cheapest airline that flies from Panama City NW Florida Beaches to South Carolina?

American Airlines, Delta, and Southwest are the most popular carriers operating from Panama City NW Florida Beaches to South Carolina

Cheap Panama City, Florida to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South Carolina

Fastest flight time

Direct flights

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?

How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?

What documentation or ID do you need to fly to South Carolina?

Best airlines flying from Panama City, Florida to South Carolina

Compare and see reviews for airlines that fly from Panama City, Florida to South Carolina with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to South Carolina?

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo