What is the cheapest airline that flies from Panama City NW Florida Beaches to South Carolina?

Southwest, American Airlines, and Delta are the most popular carriers operating from Panama City NW Florida Beaches to South Carolina

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?

Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?

There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of June 2026.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$142 Cheap Flights from Panama City, Florida to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City, Florida to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:30 am - 7:20 pm

ECP

MYR

6h 50m

1 stop

11:55 am - 6:05 pm

MYR

ECP

7h 10m

1 stop

$281Southwest

Tue, Sep 15 - Sat, Sep 19

10:30 am - 7:20 pm

ECP

MYR

7h 50m

2 stops

7:55 am - 1:55 pm

MYR

ECP

7h 00m

1 stop

$286Southwest

Tue, Sep 15 - Sat, Sep 19

6:00 am - 10:47 am

ECP

MYR

3h 47m

1 stop

6:00 am - 8:18 am

MYR

ECP

3h 18m

1 stop

$295Delta

Sun, Sep 6 - Sat, Sep 12

7:45 am - 7:10 pm

ECP

MYR

10h 25m

2 stops

7:55 am - 6:05 pm

MYR

ECP

11h 10m

2 stops

$297Southwest

Tue, Sep 15 - Sat, Sep 19

5:03 pm - 11:55 pm

ECP

MYR

5h 52m

1 stop

7:59 pm - 11:37 pm

MYR

ECP

4h 38m

1 stop

$310Delta

Tue, Jul 21 - Sun, Jul 26

4:17 pm - 11:51 pm

ECP

GSP

6h 34m

1 stop

6:18 pm - 11:37 pm

GSP

ECP

6h 19m

1 stop

$310American Airlines

Mon, Jul 27 - Tue, Jul 28

1:25 pm - 10:55 pm

ECP

GSP

8h 30m

2 stops

7:00 am - 9:30 am

GSP

ECP

3h 30m

1 stop

$315Southwest

Mon, Jul 27 - Tue, Jul 28

6:54 pm - 11:51 pm

ECP

MYR

3h 57m

1 stop

1:01 pm - 3:47 pm

MYR

ECP

3h 46m

1 stop

$330American Airlines

Sat, Jul 11 - Tue, Jul 14

1:47 pm - 9:07 pm

ECP

GSP

6h 20m

1 stop

6:30 am - 1:06 pm

GSP

ECP

7h 36m

1 stop

$343United Airlines

Tue, Aug 18 - Wed, Aug 19

1:47 pm - 9:07 pm

ECP

GSP

6h 20m

1 stop

6:30 am - 1:06 pm

GSP

ECP

7h 36m

1 stop

$364United Airlines

Tue, Aug 18 - Wed, Aug 19

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American Airlines flights from Panama City, Florida to South Carolina

Our best American Airlines deals on Panama City, Florida to South Carolina flight tickets

American Airlines

Jul 27

ECP4:17 pmPanama City NW Florida Beaches

6h 34m

1 stop

GSP11:51 pmGreenville

Jul 28

GSP6:18 pmGreenville

6h 19m

1 stop

ECP11:37 pmPanama City NW Florida Beaches

$310

American Airlines

Jul 11

ECP6:54 pmPanama City NW Florida Beaches

3h 57m

1 stop

MYR11:51 pmMyrtle Beach Intl

Jul 14

MYR1:01 pmMyrtle Beach Intl

3h 46m

1 stop

ECP3:47 pmPanama City NW Florida Beaches

$330

American Airlines

Jul 29

ECP11:55 amPanama City NW Florida Beaches

8h 59m

1 stop

CHS9:54 pmCharleston

Aug 5

CHS6:00 amCharleston

12h 16m

2 stops

ECP5:16 pmPanama City NW Florida Beaches

$360

Delta flights from Panama City, Florida to South Carolina

Our best Delta deals on Panama City, Florida to South Carolina flight tickets

Delta

Sep 6

ECP6:00 amPanama City NW Florida Beaches

3h 47m

1 stop

MYR10:47 amMyrtle Beach Intl

Sep 12

MYR6:00 amMyrtle Beach Intl

3h 18m

1 stop

ECP8:18 amPanama City NW Florida Beaches

$295

Delta

Jul 21

ECP5:03 pmPanama City NW Florida Beaches

5h 52m

1 stop

MYR11:55 pmMyrtle Beach Intl

Jul 26

MYR7:59 pmMyrtle Beach Intl

4h 38m

1 stop

ECP11:37 pmPanama City NW Florida Beaches

$310

Delta

Jul 29

ECP9:12 amPanama City NW Florida Beaches

5h 41m

1 stop

CHS3:53 pmCharleston

Aug 5

CHS6:45 pmCharleston

3h 55m

1 stop

ECP9:40 pmPanama City NW Florida Beaches

$337

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 9/15

11:30 am-7:20 pm

1 stop6h 50m

Myrtle Beach Intl

Sat 9/19

11:55 am-6:05 pm

1 stop7h 10m

$281

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 9/15

10:30 am-7:20 pm

2 stops7h 50m

Myrtle Beach Intl

Sat 9/19

7:55 am-1:55 pm

1 stop7h 00m

$286

Quickest round-trip

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Sun 9/6

6:00 am-10:47 am

1 stop3h 47m

Myrtle Beach Intl

Sat 9/12

6:00 am-8:18 am

1 stop3h 18m

$295

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 9/15

7:45 am-7:10 pm

2 stops10h 25m

Myrtle Beach Intl

Sat 9/19

7:55 am-6:05 pm

2 stops11h 10m

$297

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 7/21

5:03 pm-11:55 pm

1 stop5h 52m

Myrtle Beach Intl

Sun 7/26

7:59 pm-11:37 pm

1 stop4h 38m

$310

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 7/27

4:17 pm-11:51 pm

1 stop6h 34m

Greenville

Tue 7/28

6:18 pm-11:37 pm

1 stop6h 19m

$310

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 7/27

1:25 pm-10:55 pm

2 stops8h 30m

Greenville

Tue 7/28

7:00 am-9:30 am

1 stop3h 30m

$315

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Sat 7/11

6:54 pm-11:51 pm

1 stop3h 57m

Myrtle Beach Intl

Tue 7/14

1:01 pm-3:47 pm

1 stop3h 46m

$330

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 8/18

1:47 pm-9:07 pm

1 stop6h 20m

Greenville

Wed 8/19

6:30 am-1:06 pm

1 stop7h 36m

$343

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 8/18

1:47 pm-9:07 pm

1 stop6h 20m

Greenville

Wed 8/19

6:30 am-1:06 pm

1 stop7h 36m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Panama City, Florida is in June. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Panama City, Florida during September instead. Flights to South Carolina in September, while not as cheap as those in June, still average around $185.

Can stopping save me money on Panama City, Florida to South Carolina flights?

You could potentially save up to 5% on your flight if you consider stops on a Panama City, Florida to South Carolina flight.

Cheap Panama City, Florida to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South Carolina

Fastest flight time	3h 06m
Direct flights	None

The fastest flight from Panama City, Florida to South Carolina takes 3h 06m

There are no direct flights from Panama City, Florida to South Carolina. There are no popular flight routes from Panama City, Florida to South Carolina.

Search flight deals

Frequently asked questions about flying from Panama City, Florida to South Carolina

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South Carolina?
Prices for flights from Panama City NW Florida Beaches Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South Carolina?
There is 1 operator available for flights from Panama City NW Florida Beaches Airport to South Carolina as of June 2026.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama City, Florida to South Carolina

Compare and see reviews for airlines that fly from Panama City, Florida to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $138	Free Cancellation	Rating 7.8 8,424 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South Carolina?

It is quick and easy to find Panama City to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Panama City to South Carolina with flexible booking policies on momondo?

Flights from Panama City to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to South Carolina?

momondo helps you find the best flight between Panama City and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.