Cheap flights from Panama City, Florida to South America from $338

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to South America departing on 6/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:38 pm - 1:05 pm
ECP
-
BOG
21h 27m
2 stops
American Airlines Logo
6:30 am - 10:36 pm
BOG
-
ECP
16h 06m
2 stops
$582American Airlines
Sat, May 9 - Fri, May 22
American Airlines Logo
4:40 pm - 1:05 pm
ECP
-
BOG
20h 25m
2 stops
American Airlines Logo
6:30 am - 11:46 pm
BOG
-
ECP
17h 16m
2 stops
$585American Airlines
Wed, Apr 29 - Wed, May 6
American Airlines Logo
7:00 am - 10:30 pm
ECP
-
BOG
15h 30m
1 stop
American Airlines Logo
12:15 am - 10:36 pm
BOG
-
ECP
22h 21m
1 stop
$586American Airlines
Sat, May 9 - Thu, May 21
United Airlines Logo
6:30 am - 7:20 pm
ECP
-
BOG
12h 50m
1 stop
United Airlines Logo
12:14 am - 9:35 am
BOG
-
ECP
9h 21m
1 stop
$591United Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
7:21 am - 9:17 pm
ECP
-
BOG
13h 56m
2 stops
American Airlines Logo
2:10 pm - 12:38 pm
BOG
-
ECP
22h 28m
2 stops
$595American Airlines
Thu, Apr 30 - Fri, May 8
United Airlines Logo
10:30 am - 4:54 am
ECP
-
BOG
18h 24m
2 stops
United Airlines Logo
12:14 am - 9:35 am
BOG
-
ECP
9h 21m
1 stop
$596United Airlines
Fri, May 1 - Mon, May 4
United Airlines Logo
10:10 am - 7:20 pm
ECP
-
BOG
9h 10m
1 stop
United Airlines Logo
8:30 am - 10:05 pm
BOG
-
ECP
13h 35m
1 stop
$600United Airlines
Wed, Apr 29 - Wed, May 6
Avianca Logo
11:40 am - 2:20 am
ECP
-
LPB
13h 40m
2 stops
Avianca Logo
3:25 am - 8:03 pm
LPB
-
ECP
17h 38m
2 stops
$1,359Avianca
Sun, Jul 19 - Thu, Jul 23
Avianca Logo
5:05 pm - 2:45 pm
ECP
-
LPB
20h 40m
3 stops
Avianca Logo
3:25 am - 8:03 pm
LPB
-
ECP
17h 38m
2 stops
$1,681Avianca
Sun, Jul 19 - Thu, Jul 23
Multiple Airlines Logo
11:40 am - 2:45 pm
ECP
-
LPB
26h 05m
3 stops
Multiple Airlines Logo
3:50 pm - 4:23 pm
LPB
-
ECP
25h 33m
3 stops
$3,562Multiple Airlines
Sun, Jul 19 - Fri, Jul 24

LATAM Airlines flights from Panama City, Florida to South America

Our best LATAM Airlines deals on Panama City, Florida to South America flight tickets
LATAM Airlines
Apr 19
ECP7:05 amPanama City NW Florida Beaches
6h 35m
1 stop
BOG1:40 pmBogotá El Dorado
Apr 22
BOG10:05 pmBogotá El Dorado
25h 07m
2 stops
ECP11:12 pmPanama City NW Florida Beaches
$663
LATAM Airlines
Apr 3
ECP6:00 amPanama City NW Florida Beaches
13h 15m
1 stop
BOG7:15 pmBogotá El Dorado
Apr 5
BOG9:00 amBogotá El Dorado
12h 22m
1 stop
ECP9:22 pmPanama City NW Florida Beaches
$739
LATAM Airlines
Apr 1
ECP8:25 amPanama City NW Florida Beaches
10h 50m
1 stop
BOG7:15 pmBogotá El Dorado
Apr 3
BOG2:55 pmBogotá El Dorado
17h 45m
1 stop
ECP8:40 amPanama City NW Florida Beaches
$746

American Airlines flights from Panama City, Florida to South America

Our best American Airlines deals on Panama City, Florida to South America flight tickets
American Airlines
May 9
ECP3:38 pmPanama City NW Florida Beaches
21h 27m
2 stops
BOG1:05 pmBogotá El Dorado
May 22
BOG6:30 amBogotá El Dorado
16h 06m
2 stops
ECP10:36 pmPanama City NW Florida Beaches
$582
American Airlines
Apr 29
ECP4:40 pmPanama City NW Florida Beaches
20h 25m
2 stops
BOG1:05 pmBogotá El Dorado
May 6
BOG6:30 amBogotá El Dorado
17h 16m
2 stops
ECP11:46 pmPanama City NW Florida Beaches
$585
American Airlines
May 9
ECP7:00 amPanama City NW Florida Beaches
15h 30m
1 stop
BOG10:30 pmBogotá El Dorado
May 21
BOG12:15 amBogotá El Dorado
22h 21m
1 stop
ECP10:36 pmPanama City NW Florida Beaches
$586

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Panama City, Florida to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sat 5/9

3:38 pm-1:05 pm

2 stops21h 27m

Bogotá El Dorado

Fri 5/22

6:30 am-10:36 pm

2 stops16h 06m

$582

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Wed 4/29

4:40 pm-1:05 pm

2 stops20h 25m

Bogotá El Dorado

Wed 5/6

6:30 am-11:46 pm

2 stops17h 16m

$585

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sat 5/9

7:00 am-10:30 pm

1 stop15h 30m

Bogotá El Dorado

Thu 5/21

12:15 am-10:36 pm

1 stop22h 21m

$586
Quickest round-trip

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 5/1

6:30 am-7:20 pm

1 stop12h 50m

Bogotá El Dorado

Mon 5/4

12:14 am-9:35 am

1 stop9h 21m

$591

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 4/30

7:21 am-9:17 pm

2 stops13h 56m

Bogotá El Dorado

Fri 5/8

2:10 pm-12:38 pm

2 stops22h 28m

$595

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 5/1

10:30 am-4:54 am

2 stops18h 24m

Bogotá El Dorado

Mon 5/4

12:14 am-9:35 am

1 stop9h 21m

$596

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Wed 4/29

10:10 am-7:20 pm

1 stop9h 10m

Bogotá El Dorado

Wed 5/6

8:30 am-10:05 pm

1 stop13h 35m

$600

Panama CityLa Paz

ECP - LPB

ECPLPB

Panama City NW Florida Beaches

Sun 7/19

11:40 am-2:20 am

2 stops13h 40m

La Paz El Alto Intl

Thu 7/23

3:25 am-8:03 pm

2 stops17h 38m

$1,359

Panama CityLa Paz

ECP - LPB

ECPLPB

Panama City NW Florida Beaches

Sun 7/19

5:05 pm-2:45 pm

3 stops20h 40m

La Paz El Alto Intl

Thu 7/23

3:25 am-8:03 pm

2 stops17h 38m

$1,681

Panama CityLa Paz

ECP - LPB

ECPLPB

Panama City NW Florida Beaches

Sun 7/19

11:40 am-2:45 pm

3 stops26h 05m

La Paz El Alto Intl

Fri 7/24

3:50 pm-4:23 pm

3 stops25h 33m

$3,562

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama City NW Florida Beaches to South America?

American Airlines and United Airlines are the most popular carriers operating from Panama City NW Florida Beaches to South America

What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Panama City, Florida according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

Cheap Panama City, Florida to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South America

Fastest flight time

9h 10m

Direct flights

None
The fastest flight from Panama City, Florida to South America takes 9h 10m
There are no direct flights from Panama City, Florida to South America. There are no popular flight routes from Panama City, Florida to South America.
  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South America?

    Prices for flights from Panama City NW Florida Beaches Airport to South America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to South America

Compare and see reviews for airlines that fly from Panama City, Florida to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $507Free CancellationRating
7.9
8,296 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Panama City with this policy.

How can momondo help me find flights from Panama City to South America?

Once you have performed a search for Panama City to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Wed 4/15
Wed 4/22

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Popular flights according to clicks in the last 7 days on momondo