Cheap flights from Panama City, Florida to South America from $348

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to South America departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 7:20 pm
ECP
-
BOG
12h 50m
1 stop
United Airlines Logo
9:48 am - 9:37 am
BOG
-
ECP
24h 49m
2 stops
$592United Airlines
Tue, Oct 6 - Sat, Mar 6
Delta Logo
6:00 am - 1:40 pm
ECP
-
BOG
7h 40m
1 stop
Delta Logo
3:40 pm - 8:17 am
BOG
-
ECP
17h 37m
1 stop
$597Delta
Tue, Oct 6 - Sat, Mar 6
United Airlines Logo
10:25 am - 4:54 am
ECP
-
BOG
18h 29m
2 stops
United Airlines Logo
12:14 am - 11:03 am
BOG
-
ECP
10h 49m
1 stop
$602United Airlines
Fri, Sep 11 - Fri, Sep 18
Delta Logo
7:45 am - 7:15 pm
ECP
-
BOG
11h 30m
1 stop
Delta Logo
3:40 pm - 8:17 am
BOG
-
ECP
17h 37m
1 stop
$617Delta
Tue, Oct 6 - Sat, Mar 6
American Airlines Logo
7:30 am - 10:57 pm
ECP
-
BOG
15h 27m
1 stop
American Airlines Logo
11:45 pm - 2:25 pm
BOG
-
ECP
14h 40m
1 stop
$671American Airlines
Fri, Oct 2 - Sun, Oct 4
United Airlines Logo
6:30 am - 7:20 pm
ECP
-
BOG
12h 50m
1 stop
United Airlines Logo
8:30 am - 1:09 pm
BOG
-
ECP
28h 39m
2 stops
$674United Airlines
Fri, Oct 2 - Sun, Oct 4
American Airlines Logo
3:17 pm - 12:50 pm
ECP
-
BOG
21h 33m
2 stops
American Airlines Logo
2:35 pm - 11:38 am
BOG
-
ECP
21h 03m
2 stops
$676American Airlines
Fri, Oct 2 - Sun, Oct 4
LATAM Airlines Logo
7:05 pm - 7:50 pm
ECP
-
BGA
24h 45m
2 stops
LATAM Airlines Logo
6:40 am - 10:47 pm
BGA
-
ECP
16h 07m
2 stops
$804LATAM Airlines
Mon, Oct 19 - Thu, Oct 22
LATAM Airlines Logo
6:00 am - 1:00 am
ECP
-
CUZ
19h 00m
3 stops
LATAM Airlines Logo
11:20 pm - 5:50 pm
CUZ
-
ECP
42h 30m
3 stops
$1,194LATAM Airlines
Fri, Oct 16 - Sat, Oct 24
Multiple Airlines Logo
2:46 pm - 8:26 pm
ECP
-
COR
27h 40m
2 stops
Multiple Airlines Logo
1:20 pm - 10:48 am
COR
-
ECP
23h 28m
2 stops
$1,994Multiple Airlines
Mon, Jun 15 - Mon, Jul 6

United Airlines flights from Panama City, Florida to South America

Our best United Airlines deals on Panama City, Florida to South America flight tickets
United Airlines
Oct 6
ECP6:30 amPanama City NW Florida Beaches
12h 50m
1 stop
BOG7:20 pmBogotá El Dorado
Mar 6
BOG9:48 amBogotá El Dorado
24h 49m
2 stops
ECP9:37 amPanama City NW Florida Beaches
$592
United Airlines
Sep 11
ECP10:25 amPanama City NW Florida Beaches
18h 29m
2 stops
BOG4:54 amBogotá El Dorado
Sep 18
BOG12:14 amBogotá El Dorado
10h 49m
1 stop
ECP11:03 amPanama City NW Florida Beaches
$602
United Airlines
Oct 1
ECP2:15 pmPanama City NW Florida Beaches
14h 39m
2 stops
BOG4:54 amBogotá El Dorado
Oct 4
BOG8:30 amBogotá El Dorado
25h 07m
2 stops
ECP9:37 amPanama City NW Florida Beaches
$672

Delta flights from Panama City, Florida to South America

Our best Delta deals on Panama City, Florida to South America flight tickets
Delta
Oct 6
ECP6:00 amPanama City NW Florida Beaches
7h 40m
1 stop
BOG1:40 pmBogotá El Dorado
Mar 6
BOG3:40 pmBogotá El Dorado
17h 37m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$597
Delta
Oct 6
ECP7:45 amPanama City NW Florida Beaches
11h 30m
1 stop
BOG7:15 pmBogotá El Dorado
Mar 6
BOG3:40 pmBogotá El Dorado
17h 37m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$617
Delta
Jul 8
ECP6:00 amPanama City NW Florida Beaches
13h 15m
1 stop
BOG7:15 pmBogotá El Dorado
Oct 7
BOG9:00 amBogotá El Dorado
10h 36m
1 stop
ECP7:36 pmPanama City NW Florida Beaches
$771

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Panama City, Florida to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Tue 10/6

6:30 am-7:20 pm

1 stop12h 50m

Bogotá El Dorado

Sat 3/6

9:48 am-9:37 am

2 stops24h 49m

$592
Quickest round-trip

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Tue 10/6

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Sat 3/6

3:40 pm-8:17 am

1 stop17h 37m

$597

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 9/11

10:25 am-4:54 am

2 stops18h 29m

Bogotá El Dorado

Fri 9/18

12:14 am-11:03 am

1 stop10h 49m

$602

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Tue 10/6

7:45 am-7:15 pm

1 stop11h 30m

Bogotá El Dorado

Sat 3/6

3:40 pm-8:17 am

1 stop17h 37m

$617

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 10/2

7:30 am-10:57 pm

1 stop15h 27m

Bogotá El Dorado

Sun 10/4

11:45 pm-2:25 pm

1 stop14h 40m

$671

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 10/2

6:30 am-7:20 pm

1 stop12h 50m

Bogotá El Dorado

Sun 10/4

8:30 am-1:09 pm

2 stops28h 39m

$674

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 10/2

3:17 pm-12:50 pm

2 stops21h 33m

Bogotá El Dorado

Sun 10/4

2:35 pm-11:38 am

2 stops21h 03m

$676

Panama CityBucaramanga

ECP - BGA

ECPBGA

Panama City NW Florida Beaches

Mon 10/19

7:05 pm-7:50 pm

2 stops24h 45m

Bucaramanga Palo Negro

Thu 10/22

6:40 am-10:47 pm

2 stops16h 07m

$804

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Fri 10/16

6:00 am-1:00 am

3 stops19h 00m

Cusco Velazco Astete

Sat 10/24

11:20 pm-5:50 pm

3 stops42h 30m

$1,194

Panama CityCordoba

ECP - COR

ECPCOR

Panama City NW Florida Beaches

Mon 6/15

2:46 pm-8:26 pm

2 stops27h 40m

Cordoba Pajas Blancas

Mon 7/6

1:20 pm-10:48 am

2 stops23h 28m

$1,994

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama City NW Florida Beaches to South America?

American Airlines, Copa Airlines, and United Airlines are the most popular carriers operating from Panama City NW Florida Beaches to South America

What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Panama City, Florida according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

Cheap Panama City, Florida to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South America

Fastest flight time

11h 30m

Direct flights

None
The fastest flight from Panama City, Florida to South America takes 11h 30m
There are no direct flights from Panama City, Florida to South America. There are no popular flight routes from Panama City, Florida to South America.

Frequently asked questions about flying from Panama City, Florida to South America

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South America?

    Prices for flights from Panama City NW Florida Beaches Airport to South America are updated daily.

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to South America

Compare and see reviews for airlines that fly from Panama City, Florida to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $664Free CancellationRating
7.9
8,456 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Panama City with this policy.

How can momondo help me find flights from Panama City to South America?

Once you have performed a search for Panama City to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Sun 6/7
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Popular flights according to clicks in the last 7 days on momondo