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Cheap flights from Panama City, Florida to South America from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to South America departing on 2/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:10 pm - 5:30 am
ECP
-
BOG
14h 20m
1 stop
Multiple Airlines Logo
9:10 am - 9:57 pm
BOG
-
ECP
12h 47m
2 stops
$521Multiple Airlines
Thu, Mar 5 - Wed, Mar 11
Multiple Airlines Logo
6:30 am - 1:50 am
ECP
-
BOG
18h 20m
2 stops
Multiple Airlines Logo
4:00 am - 4:11 pm
BOG
-
ECP
13h 11m
2 stops
$522Multiple Airlines
Fri, Feb 13 - Sun, Feb 15
Multiple Airlines Logo
1:10 pm - 1:50 am
ECP
-
BOG
11h 40m
2 stops
Multiple Airlines Logo
4:00 am - 4:11 pm
BOG
-
ECP
13h 11m
2 stops
$550Multiple Airlines
Wed, Feb 11 - Sat, Feb 14
Delta Logo
7:45 am - 7:25 pm
ECP
-
BOG
11h 40m
1 stop
Delta Logo
2:55 pm - 8:17 am
BOG
-
ECP
17h 22m
1 stop
$557Delta
Sat, May 9 - Fri, May 22
American Airlines Logo
6:44 am - 10:30 pm
ECP
-
BOG
15h 46m
1 stop
American Airlines Logo
12:25 pm - 10:25 am
BOG
-
ECP
22h 00m
2 stops
$562American Airlines
Sat, May 9 - Fri, May 22
United Airlines Logo
6:30 am - 8:46 pm
ECP
-
GYE
37h 16m
2 stops
United Airlines Logo
2:35 pm - 9:57 pm
GYE
-
ECP
55h 22m
2 stops
$566United Airlines
Mon, Mar 2 - Mon, Mar 9
Azul Logo
6:30 am - 10:35 pm
ECP
-
BOG
15h 05m
1 stop
Azul Logo
8:15 am - 9:57 pm
BOG
-
ECP
13h 42m
1 stop
$582Azul
Thu, Mar 5 - Wed, Mar 11
United Airlines Logo
5:00 pm - 5:10 am
ECP
-
BOG
11h 10m
1 stop
United Airlines Logo
1:30 am - 12:04 pm
BOG
-
ECP
11h 34m
1 stop
$583United Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
6:43 pm - 1:05 pm
ECP
-
BOG
18h 22m
2 stops
American Airlines Logo
2:10 pm - 10:25 am
BOG
-
ECP
20h 15m
2 stops
$587American Airlines
Sat, May 30 - Mon, Jun 1
American Airlines Logo
6:42 am - 11:30 pm
ECP
-
BOG
15h 48m
1 stop
American Airlines Logo
3:15 pm - 12:08 pm
BOG
-
ECP
21h 53m
2 stops
$588American Airlines
Thu, Feb 26 - Tue, Mar 3

Delta flights from Panama City, Florida to South America

Our best Delta deals on Panama City, Florida to South America flight tickets
Delta
May 9
ECP7:45 amPanama City NW Florida Beaches
11h 40m
1 stop
BOG7:25 pmBogotá El Dorado
May 22
BOG2:55 pmBogotá El Dorado
17h 22m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$557
Delta
Feb 13
ECP8:03 amPanama City NW Florida Beaches
10h 27m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 16
BOG3:55 pmBogotá El Dorado
17h 46m
1 stop
ECP8:41 amPanama City NW Florida Beaches
$636

LATAM Airlines flights from Panama City, Florida to South America

Our best LATAM Airlines deals on Panama City, Florida to South America flight tickets
LATAM Airlines
Feb 13
ECP6:00 amPanama City NW Florida Beaches
7h 25m
1 stop
BOG2:25 pmBogotá El Dorado
Feb 14
BOG3:55 pmBogotá El Dorado
17h 46m
1 stop
ECP8:41 amPanama City NW Florida Beaches
$697
LATAM Airlines
Feb 11
ECP9:24 amPanama City NW Florida Beaches
9h 06m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 15
BOG3:55 pmBogotá El Dorado
7h 44m
1 stop
ECP10:39 pmPanama City NW Florida Beaches
$706
LATAM Airlines
Feb 11
ECP6:00 amPanama City NW Florida Beaches
7h 25m
1 stop
BOG2:25 pmBogotá El Dorado
Feb 15
BOG12:15 pmBogotá El Dorado
11h 24m
2 stops
ECP10:39 pmPanama City NW Florida Beaches
$717

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City, Florida to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 3/5

2:10 pm-5:30 am

1 stop14h 20m

Bogotá El Dorado

Wed 3/11

9:10 am-9:57 pm

2 stops12h 47m

$521

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Fri 2/13

6:30 am-1:50 am

2 stops18h 20m

Bogotá El Dorado

Sun 2/15

4:00 am-4:11 pm

2 stops13h 11m

$522

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Wed 2/11

1:10 pm-1:50 am

2 stops11h 40m

Bogotá El Dorado

Sat 2/14

4:00 am-4:11 pm

2 stops13h 11m

$550

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sat 5/9

7:45 am-7:25 pm

1 stop11h 40m

Bogotá El Dorado

Fri 5/22

2:55 pm-8:17 am

1 stop17h 22m

$557

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sat 5/9

6:44 am-10:30 pm

1 stop15h 46m

Bogotá El Dorado

Fri 5/22

12:25 pm-10:25 am

2 stops22h 00m

$562

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

Mon 3/2

6:30 am-8:46 pm

2 stops37h 16m

Guayaquil Jose Joaquin de Olmedo

Mon 3/9

2:35 pm-9:57 pm

2 stops55h 22m

$566

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 3/5

6:30 am-10:35 pm

1 stop15h 05m

Bogotá El Dorado

Wed 3/11

8:15 am-9:57 pm

1 stop13h 42m

$582

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 2/26

5:00 pm-5:10 am

1 stop11h 10m

Bogotá El Dorado

Mon 3/2

1:30 am-12:04 pm

1 stop11h 34m

$583

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sat 5/30

6:43 pm-1:05 pm

2 stops18h 22m

Bogotá El Dorado

Mon 6/1

2:10 pm-10:25 am

2 stops20h 15m

$587

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 2/26

6:42 am-11:30 pm

1 stop15h 48m

Bogotá El Dorado

Tue 3/3

3:15 pm-12:08 pm

2 stops21h 53m

$588

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama City NW Florida Beaches to South America?

Delta and American Airlines are the most popular carriers operating from Panama City NW Florida Beaches to South America

What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Panama City, Florida according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

Cheap Panama City, Florida to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South America

Fastest flight time

10h 27m

Direct flights

None
The fastest flight from Panama City, Florida to South America takes 10h 27m
There are no direct flights from Panama City, Florida to South America. There are no popular flight routes from Panama City, Florida to South America.
Search flight deals

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South America?

    Prices for flights from Panama City NW Florida Beaches Airport to South America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to South America

Compare and see reviews for airlines that fly from Panama City, Florida to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $482Free CancellationRating
7.9
8,128 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Panama City with this policy.

How can momondo help me find flights from Panama City to South America?

Once you have performed a search for Panama City to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
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Flights to Bogotáfrom $161
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Flights to Santiagofrom $326
Flights to Cartagenafrom $166
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Flights to Guayaquilfrom $160
Flights to Califrom $168