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Cheap flights from Panama City, Florida to South America from $358

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to South America departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to South America

Cheap round-trip flights

Delta Logo
4:25 pm - 12:00 pmECP-BOG
19h 35m2 stops
Delta Logo
9:00 am - 5:52 pmBOG-ECP
9h 52m1 stop
$503Delta
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Mon, Oct 6 - Thu, Mar 5
Delta Logo
6:00 am - 1:40 pmECP-BOG
7h 40m1 stop
Delta Logo
1:35 am - 5:52 pmBOG-ECP
17h 17m2 stops
$507Delta
Find Deal
Mon, Oct 6 - Wed, Mar 4
United Airlines Logo
6:30 am - 7:20 pmECP-BOG
12h 50m1 stop
United Airlines Logo
1:30 am - 11:52 amBOG-ECP
11h 22m1 stop
$508United Airlines
Find Deal
Mon, Oct 6 - Wed, Mar 4
United Airlines Logo
5:06 pm - 4:54 amECP-BOG
11h 48m1 stop
United Airlines Logo
8:30 am - 8:16 pmBOG-ECP
11h 46m1 stop
$538United Airlines
Find Deal
Thu, Sep 11 - Thu, Sep 18
United Airlines Logo
3:03 pm - 4:54 amECP-BOG
13h 51m1 stop
United Airlines Logo
12:14 am - 8:16 pmBOG-ECP
20h 02m1 stop
$546United Airlines
Find Deal
Thu, Sep 11 - Wed, Sep 17
Delta Logo
5:00 am - 5:18 amECP-BGA
23h 18m2 stops
Delta Logo
10:40 pm - 11:10 pmBGA-ECP
25h 30m2 stops
$554Delta
Find Deal
Sun, Nov 2 - Wed, Nov 5
American Airlines Logo
10:13 am - 9:17 pmECP-BOG
11h 04m2 stops
American Airlines Logo
2:10 pm - 11:31 amBOG-ECP
21h 21m2 stops
$562American Airlines
Find Deal
Thu, Sep 11 - Thu, Sep 18
American Airlines Logo
3:29 pm - 1:05 pmECP-BOG
21h 36m2 stops
American Airlines Logo
12:25 am - 9:08 pmBOG-ECP
20h 43m1 stop
$571American Airlines
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Sun, Sep 14 - Sat, Sep 20
Logo
5:06 pm - 10:40 pmECP-GYE
29h 34m2 stops
Logo
8:32 am - 9:54 amGYE-ECP
25h 22m2 stops
$676
Find Deal
Mon, Aug 25 - Sat, Aug 30
Logo
5:06 pm - 11:20 pmECP-GYE
30h 14m2 stops
Logo
3:15 am - 9:54 amGYE-ECP
30h 39m2 stops
$686
Find Deal
Mon, Aug 25 - Fri, Aug 29

American Airlines flights from Panama City, Florida to South America

Our best American Airlines deals on Panama City, Florida to South America flight tickets
American Airlines
Sep 11
ECP10:13 amPanama City NW Florida Beaches
11h 04m
2 stops
BOG9:17 pmBogotá El Dorado
Sep 18
BOG2:10 pmBogotá El Dorado
21h 21m
2 stops
ECP11:31 amPanama City NW Florida Beaches
$562
Find similar
American Airlines
Sep 14
ECP3:29 pmPanama City NW Florida Beaches
21h 36m
2 stops
BOG1:05 pmBogotá El Dorado
Sep 20
BOG12:25 amBogotá El Dorado
20h 43m
1 stop
ECP9:08 pmPanama City NW Florida Beaches
$571
Find similar
American Airlines
Sep 14
ECP6:35 amPanama City NW Florida Beaches
16h 04m
1 stop
BOG10:39 pmBogotá El Dorado
Sep 21
BOG2:10 pmBogotá El Dorado
24h 10m
2 stops
ECP2:20 pmPanama City NW Florida Beaches
$572
Find similar

United Airlines flights from Panama City, Florida to South America

Our best United Airlines deals on Panama City, Florida to South America flight tickets
United Airlines
Oct 6
ECP6:30 amPanama City NW Florida Beaches
12h 50m
1 stop
BOG7:20 pmBogotá El Dorado
Mar 4
BOG1:30 amBogotá El Dorado
11h 22m
1 stop
ECP11:52 amPanama City NW Florida Beaches
$508
Find similar
United Airlines
Sep 11
ECP5:06 pmPanama City NW Florida Beaches
11h 48m
1 stop
BOG4:54 amBogotá El Dorado
Sep 18
BOG8:30 amBogotá El Dorado
11h 46m
1 stop
ECP8:16 pmPanama City NW Florida Beaches
$538
Find similar
United Airlines
Sep 11
ECP3:03 pmPanama City NW Florida Beaches
13h 51m
1 stop
BOG4:54 amBogotá El Dorado
Sep 17
BOG12:14 amBogotá El Dorado
20h 02m
1 stop
ECP8:16 pmPanama City NW Florida Beaches
$546
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Panama City, Florida to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 10/6

4:25 pm-12:00 pm

2 stops19h 35m

Bogotá El Dorado

Thu 3/5

9:00 am-5:52 pm

1 stop9h 52m

$503

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 10/6

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Wed 3/4

1:35 am-5:52 pm

2 stops17h 17m

$507

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 10/6

6:30 am-7:20 pm

1 stop12h 50m

Bogotá El Dorado

Wed 3/4

1:30 am-11:52 am

1 stop11h 22m

$508

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 9/11

5:06 pm-4:54 am

1 stop11h 48m

Bogotá El Dorado

Thu 9/18

8:30 am-8:16 pm

1 stop11h 46m

$538

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 9/11

3:03 pm-4:54 am

1 stop13h 51m

Bogotá El Dorado

Wed 9/17

12:14 am-8:16 pm

1 stop20h 02m

$546

Panama CityBucaramanga

ECP - BGA

ECPBGA

Panama City NW Florida Beaches

Sun 11/2

5:00 am-5:18 am

2 stops23h 18m

Bucaramanga Palo Negro

Wed 11/5

10:40 pm-11:10 pm

2 stops25h 30m

$554

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Thu 9/11

10:13 am-9:17 pm

2 stops11h 04m

Bogotá El Dorado

Thu 9/18

2:10 pm-11:31 am

2 stops21h 21m

$562

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Sun 9/14

3:29 pm-1:05 pm

2 stops21h 36m

Bogotá El Dorado

Sat 9/20

12:25 am-9:08 pm

1 stop20h 43m

$571

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

Mon 8/25

5:06 pm-10:40 pm

2 stops29h 34m

Guayaquil Jose Joaquin de Olmedo

Sat 8/30

8:32 am-9:54 am

2 stops25h 22m

$676

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

Mon 8/25

5:06 pm-11:20 pm

2 stops30h 14m

Guayaquil Jose Joaquin de Olmedo

Fri 8/29

3:15 am-9:54 am

2 stops30h 39m

$686

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Panama City, Florida to South America is on a Thursday when prices can be found for as low as $643. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Panama City, Florida to South America for around $823.

Can stopping save me money on Panama City, Florida to South America flights?

You could potentially save up to 6% on your flight if you consider stops on a Panama City, Florida to South America flight.

Cheap Panama City, Florida to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to South America

Best Price Found

$358

Fastest flight time

7h 40m

Direct flights

None

Airports in South America

6 airports
The best one-way flight to South America from Panama City, Florida in the past 72 hours is $358. The best round-trip flight deal from Panama City, Florida to South America found on momondo in the last 72 hours is $503.
The fastest flight from Panama City, Florida to South America takes 7h 40m
There are no direct flights from Panama City, Florida to South America. Popular non-direct routes for this connection are Panama City NW Florida Beaches Airport - Bucaramanga Palo Negro Airport, Panama City NW Florida Beaches Airport - Bogotá El Dorado Airport and Panama City NW Florida Beaches Airport - Guayaquil Jose Joaquin de Olmedo Airport.
There are 6 airports near South America: Guayaquil Jose Joaquin de Olmedo (GYE), Trujillo (TRU), Cordoba Pajas Blancas (COR), Cusco Velazco Astete (CUZ), Bogotá El Dorado (BOG), Bucaramanga Palo Negro (BGA)
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  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to South America?

    Prices for flights from Panama City NW Florida Beaches Airport to South America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to South America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to South America

Compare and see reviews for airlines that fly from Panama City, Florida to South America with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $448Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Panama City with this policy.

How can momondo help me find flights from Panama City to South America?

Once you have performed a search for Panama City to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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