Cheap flights from Chicago O'Hare Intl Airport to South America from $176

In general, February is the cheapest month to fly from Chicago O'Hare Intl Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $539. If you aren’t able to travel during the month of February, then book flights to South America from Chicago O'Hare Intl Airport during April instead. Flights to South America in April, while not as cheap as those in February, still average around $543.

Fly from Chicago O'Hare Intl to Bogotá El Dorado for the best Chicago O'Hare Intl - South America flight prices

You are more likely to see cheaper flights to South America from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $687 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Chicago O'Hare Intl Airport for as low as $609 on momondo.

There are 3 cabin classes available to choose from on Chicago O'Hare Intl Airport to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

United Airlines, Delta, and Copa Airlines are the most popular carriers operating from Chicago O'Hare Intl to South America

Copa Airlines, Avianca and American Airlines are the top three most popular airlines that fly to South America from Chicago O'Hare Intl Airport according to our data. Copa Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 12 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

Historically, on average around 31% of flights between Chicago and South America have experienced a delay on any given week. The average delay length over the past 12 months has been 180 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, Avianca have had the least number of delays on this route over the last 12 months; with about 17% of their flights experiencing any sort of delay.

As of November 2026, 2 flights take off from Chicago O'Hare Intl Airport and land in South America each day. The most common flight departure time for this route is 5:00PM, with 60% of daily flights taking off in the afternoon.

The number of flights available between Chicago O'Hare Intl Airport and South America is 14 per week as of November 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.