Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to South America from $87

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to South America departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:15 am - 1:10 pm
ORD
-
CTG
6h 55m1 stop
Spirit Airlines Logo
2:21 pm - 11:47 pm
CTG
-
ORD
10h 26m1 stop
$275Spirit Airlines
Wed, Feb 18 - Sun, Feb 22
Spirit Airlines Logo
8:43 pm - 1:15 pm
ORD
-
CTG
15h 32m1 stop
Spirit Airlines Logo
2:21 pm - 9:03 pm
CTG
-
ORD
7h 42m1 stop
$277Spirit Airlines
Mon, Jan 12 - Fri, Jan 16
Copa Airlines Logo
2:13 pm - 8:41 am
ORD
-
CTG
17h 28m1 stop
Copa Airlines Logo
3:02 pm - 12:24 am
CTG
-
ORD
10h 22m1 stop
$290Copa Airlines
Tue, Jan 13 - Mon, Jan 26
Avianca Logo
2:35 pm - 7:14 am
ORD
-
CTG
16h 39m1 stop
Avianca Logo
9:05 pm - 1:15 pm
CTG
-
ORD
16h 10m1 stop
$297Avianca
Wed, Apr 29 - Mon, May 4
United Airlines Logo
5:45 am - 10:05 pm
ORD
-
MDE
15h 20m1 stop
United Airlines Logo
9:45 am - 9:31 pm
MDE
-
ORD
11h 46m1 stop
$303United Airlines
Sun, Mar 1 - Sat, May 9
Copa Airlines Logo
7:35 am - 8:00 pm
ORD
-
MDE
11h 25m1 stop
Copa Airlines Logo
4:30 pm - 12:24 am
MDE
-
ORD
8h 54m1 stop
$306Copa Airlines
Tue, Jan 13 - Sun, Jan 18
United Airlines Logo
8:10 pm - 10:05 pm
ORD
-
MDE
24h 55m1 stop
United Airlines Logo
9:45 am - 12:45 am
MDE
-
ORD
15h 00m1 stop
$310United Airlines
Sat, Feb 28 - Thu, May 14
American Airlines Logo
9:55 am - 8:10 pm
ORD
-
MDE
10h 15m1 stop
American Airlines Logo
12:20 am - 12:13 pm
MDE
-
ORD
11h 53m2 stops
$313American Airlines
Sun, Mar 8 - Mon, Mar 23
Avianca Logo
10:20 pm - 5:55 pm
ORD
-
UIO
18h 35m1 stop
Avianca Logo
5:05 am - 9:20 pm
UIO
-
ORD
16h 15m1 stop
$401Avianca
Wed, Feb 25 - Sun, Mar 8
American Airlines Logo
1:15 pm - 8:20 am
ORD
-
GIG
16h 05m1 stop
American Airlines Logo
10:30 pm - 11:55 am
GIG
-
ORD
16h 25m1 stop
$491American Airlines
Tue, Jan 20 - Fri, Jan 30

Delta flights from Chicago O'Hare Intl Airport to South America

Our best Delta deals on Chicago O'Hare Intl Airport to South America flight tickets
Delta
Mar 9
ORD5:20 amChicago O'Hare Intl
14h 10m
1 stop
BOG7:30 pmBogotá El Dorado
Mar 16
BOG6:15 amBogotá El Dorado
17h 44m
2 stops
ORD11:59 pmChicago O'Hare Intl
$363
Find similar
Delta
Mar 8
ORD5:20 amChicago O'Hare Intl
15h 15m
1 stop
UIO8:35 pmQuito Mariscal Sucr
Mar 18
UIO8:20 pmQuito Mariscal Sucr
20h 29m
2 stops
ORD4:49 pmChicago O'Hare Intl
$417
Find similar
Delta
Mar 12
ORD9:50 amChicago O'Hare Intl
19h 27m
2 stops
UIO5:17 amQuito Mariscal Sucr
Mar 18
UIO11:45 pmQuito Mariscal Sucr
13h 53m
1 stop
ORD1:38 pmChicago O'Hare Intl
$421
Find similar

Copa Airlines flights from Chicago O'Hare Intl Airport to South America

Our best Copa Airlines deals on Chicago O'Hare Intl Airport to South America flight tickets
Copa Airlines
Jan 13
ORD2:13 pmChicago O'Hare Intl
17h 28m
1 stop
CTG8:41 amCartagena Rafael Nunez
Jan 26
CTG3:02 pmCartagena Rafael Nunez
10h 22m
1 stop
ORD12:24 amChicago O'Hare Intl
$290
Find similar
Copa Airlines
Jan 13
ORD7:35 amChicago O'Hare Intl
11h 25m
1 stop
MDE8:00 pmMedellín Jose Maria Cordova Intl
Jan 18
MDE4:30 pmMedellín Jose Maria Cordova Intl
8h 54m
1 stop
ORD12:24 amChicago O'Hare Intl
$306
Find similar
Copa Airlines
Jan 6
ORD2:13 pmChicago O'Hare Intl
14h 37m
1 stop
BOG5:50 amBogotá El Dorado
Jan 20
BOG12:08 pmBogotá El Dorado
13h 16m
1 stop
ORD12:24 amChicago O'Hare Intl
$309
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Wed 2/18

5:15 am-1:10 pm

1 stop6h 55m

Cartagena Rafael Nunez

Sun 2/22

2:21 pm-11:47 pm

1 stop10h 26m

$275

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Mon 1/12

8:43 pm-1:15 pm

1 stop15h 32m

Cartagena Rafael Nunez

Fri 1/16

2:21 pm-9:03 pm

1 stop7h 42m

$277

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Tue 1/13

2:13 pm-8:41 am

1 stop17h 28m

Cartagena Rafael Nunez

Mon 1/26

3:02 pm-12:24 am

1 stop10h 22m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Wed 4/29

2:35 pm-7:14 am

1 stop16h 39m

Cartagena Rafael Nunez

Mon 5/4

9:05 pm-1:15 pm

1 stop16h 10m

$297

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 3/1

5:45 am-10:05 pm

1 stop15h 20m

Medellín Jose Maria Cordova Intl

Sat 5/9

9:45 am-9:31 pm

1 stop11h 46m

$303

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Tue 1/13

7:35 am-8:00 pm

1 stop11h 25m

Medellín Jose Maria Cordova Intl

Sun 1/18

4:30 pm-12:24 am

1 stop8h 54m

$306

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sat 2/28

8:10 pm-10:05 pm

1 stop24h 55m

Medellín Jose Maria Cordova Intl

Thu 5/14

9:45 am-12:45 am

1 stop15h 00m

$310

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 3/8

9:55 am-8:10 pm

1 stop10h 15m

Medellín Jose Maria Cordova Intl

Mon 3/23

12:20 am-12:13 pm

2 stops11h 53m

$313

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Wed 2/25

10:20 pm-5:55 pm

1 stop18h 35m

Quito Mariscal Sucr

Sun 3/8

5:05 am-9:20 pm

1 stop16h 15m

$401

ChicagoRio de Janeiro

ORD - GIG

ORDGIG

Chicago O'Hare Intl

Tue 1/20

1:15 pm-8:20 am

1 stop16h 05m

Rio de Janeiro–Galeão Intl

Fri 1/30

10:30 pm-11:55 am

1 stop16h 25m

$491

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Chicago O'Hare Intl Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $526. If you aren’t able to travel during the month of April, then book flights to South America from Chicago O'Hare Intl Airport during October instead. Flights to South America in October, while not as cheap as those in April, still average around $554.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Chicago O'Hare Intl Airport to South America is on a Wednesday when prices can be found for as low as $667. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to South America for around $743.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Chicago O'Hare Intl Airport to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $599. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $758 on average. Flights to South America from Chicago O'Hare Intl Airport in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Chicago O'Hare Intl to South America flight route?

Fly from Chicago O'Hare Intl to Bogotá El Dorado for the best Chicago O'Hare Intl - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $605 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Chicago O'Hare Intl Airport for as low as $483 on momondo.

What cabin class options are available on Chicago O'Hare Intl to South America flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to South America flights?

You could potentially save up to 28% on your flight if you consider stops on a Chicago O'Hare Intl Airport to South America flight.

Cheap Chicago O'Hare Intl Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to South America

Best Price Found

$264

Fastest flight time

5h 50m

Direct flights

Every day

Airports in South America

463 airports
The best one-way flight to South America from Chicago O'Hare Intl Airport in the past 72 hours is $264. The best round-trip flight deal from Chicago O'Hare Intl Airport to South America found on momondo in the last 72 hours is $397.
The fastest flight from Chicago O'Hare Intl Airport to South America takes 5h 50m
Direct flights go from Chicago O'Hare Intl Airport to South America every day.
There are 463 airports in South America. From Chicago O'Hare Intl Airport there are direct flights to Bogotá El Dorado (BOG).
Search flight deals

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to South America?

    Prices for flights from Chicago O'Hare Intl Airport to South America refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to South America?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to South America?

Best airlines flying from Chicago O'Hare Intl Airport to South America

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $240Free CancellationRating
6.3
8,190 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $292Free CancellationRating
7.5
1,894 reviews
Search LATAM Airlines flights
AviancaPriceFrom $292Free CancellationRating
6.6
2,488 reviews
Search Avianca flights
Copa AirlinesPriceFrom $299Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
8,017 reviews
Search Delta flights
United AirlinesPriceFrom $302Free CancellationRating
7.4
9,100 reviews
Search United Airlines flights
American AirlinesPriceFrom $311Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
ArajetPriceFrom $360Free CancellationRating
6.8
38 reviews
Search Arajet flights
Air CanadaPriceFrom $479Free CancellationRating
7.1
10,550 reviews
Search Air Canada flights
GOLPriceFrom $596Free CancellationRating
7.3
1,131 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South America?

It is quick and easy to find Chicago to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Chicago to South America with flexible booking policies on momondo?

Yes. All flights to South America from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to South America?

momondo provides multiple filters to help you find the best flight to South America from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 1/20
Tue 1/27
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $255
Flights to Buenos Airesfrom $481
Flights to Sao Paulofrom $373
Flights to Bogotáfrom $177
Flights to Rio de Janeirofrom $472
Flights to Medellínfrom $187
Flights to Santiagofrom $413
Flights to Cartagenafrom $173
Flights to Quitofrom $228
Flights to Cuscofrom $420
Flights to Guayaquilfrom $197
Flights to Califrom $180