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Cheap flights from Chicago O'Hare Intl Airport to Mayagüez from $347

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Mayagüez departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:17 pm - 9:42 am
ORD
-
MAZ
19h 25m
1 stop
Multiple Airlines Logo
1:19 pm - 4:37 pm
MAZ
-
ORD
29h 18m
1 stop
$347Multiple Airlines
Sun, Jan 25 - Thu, Jan 29
Multiple Airlines Logo
12:17 pm - 9:42 am
ORD
-
MAZ
19h 25m
1 stop
Multiple Airlines Logo
1:19 pm - 10:46 pm
MAZ
-
ORD
11h 27m
2 stops
$361Multiple Airlines
Sun, Jan 25 - Thu, Jan 29
Multiple Airlines Logo
12:17 pm - 4:11 pm
ORD
-
MAZ
25h 54m
1 stop
Multiple Airlines Logo
7:35 am - 10:44 pm
MAZ
-
ORD
17h 09m
2 stops
$367Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
8:43 pm - 6:43 pm
ORD
-
MAZ
20h 00m
2 stops
Multiple Airlines Logo
1:19 pm - 11:46 pm
MAZ
-
ORD
12h 27m
2 stops
$378Multiple Airlines
Sun, Jan 25 - Thu, Jan 29
Multiple Airlines Logo
6:05 am - 9:42 am
ORD
-
MAZ
25h 37m
2 stops
Multiple Airlines Logo
7:35 am - 10:03 pm
MAZ
-
ORD
16h 28m
2 stops
$391Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
5:53 pm - 6:43 pm
ORD
-
MAZ
22h 50m
3 stops
Multiple Airlines Logo
1:19 pm - 11:46 pm
MAZ
-
ORD
12h 27m
2 stops
$396Multiple Airlines
Sun, Jan 25 - Thu, Jan 29
Multiple Airlines Logo
12:17 pm - 4:11 pm
ORD
-
MAZ
25h 54m
1 stop
Multiple Airlines Logo
7:35 am - 4:37 pm
MAZ
-
ORD
11h 02m
1 stop
$399Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
5:53 pm - 6:43 pm
ORD
-
MAZ
22h 50m
3 stops
Multiple Airlines Logo
1:19 pm - 9:12 am
MAZ
-
ORD
21h 53m
3 stops
$417Multiple Airlines
Sun, Jan 25 - Thu, Jan 29
Multiple Airlines Logo
10:48 am - 9:42 am
ORD
-
MAZ
20h 54m
2 stops
Multiple Airlines Logo
7:35 am - 2:17 pm
MAZ
-
ORD
32h 42m
3 stops
$432Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
5:15 am - 9:42 am
ORD
-
MAZ
26h 27m
3 stops
Multiple Airlines Logo
7:35 am - 2:17 pm
MAZ
-
ORD
32h 42m
3 stops
$479Multiple Airlines
Tue, Jan 27 - Sat, Jan 31

United Airlines flights from Chicago O'Hare Intl Airport to Mayagüez

Our best United Airlines deals on Chicago O'Hare Intl Airport to Mayagüez flight tickets
United Airlines
Jun 20
ORD9:13 pmChicago O'Hare Intl
17h 36m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jun 30
MAZ1:25 pmMayagüez Eugenio M De Hostos
10h 47m
2 stops
ORD11:12 pmChicago O'Hare Intl
$949
United Airlines
Jun 21
ORD9:13 pmChicago O'Hare Intl
17h 36m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jun 30
MAZ1:25 pmMayagüez Eugenio M De Hostos
10h 47m
2 stops
ORD11:12 pmChicago O'Hare Intl
$956
United Airlines
Jun 20
ORD9:13 pmChicago O'Hare Intl
17h 36m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jun 29
MAZ1:25 pmMayagüez Eugenio M De Hostos
10h 47m
2 stops
ORD11:12 pmChicago O'Hare Intl
$1,044

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 1/25

12:17 pm-9:42 am

1 stop19h 25m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-4:37 pm

1 stop29h 18m

$347

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 1/25

12:17 pm-9:42 am

1 stop19h 25m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-10:46 pm

2 stops11h 27m

$361

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Tue 1/27

12:17 pm-4:11 pm

1 stop25h 54m

Mayagüez Eugenio M De Hostos

Sat 1/31

7:35 am-10:44 pm

2 stops17h 09m

$367

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 1/25

8:43 pm-6:43 pm

2 stops20h 00m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-11:46 pm

2 stops12h 27m

$378

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Tue 1/27

6:05 am-9:42 am

2 stops25h 37m

Mayagüez Eugenio M De Hostos

Sat 1/31

7:35 am-10:03 pm

2 stops16h 28m

$391

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 1/25

5:53 pm-6:43 pm

3 stops22h 50m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-11:46 pm

2 stops12h 27m

$396

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Tue 1/27

12:17 pm-4:11 pm

1 stop25h 54m

Mayagüez Eugenio M De Hostos

Sat 1/31

7:35 am-4:37 pm

1 stop11h 02m

$399

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 1/25

5:53 pm-6:43 pm

3 stops22h 50m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-9:12 am

3 stops21h 53m

$417

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Tue 1/27

10:48 am-9:42 am

2 stops20h 54m

Mayagüez Eugenio M De Hostos

Sat 1/31

7:35 am-2:17 pm

3 stops32h 42m

$432

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Tue 1/27

5:15 am-9:42 am

3 stops26h 27m

Mayagüez Eugenio M De Hostos

Sat 1/31

7:35 am-2:17 pm

3 stops32h 42m

$479

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Mayagüez from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

Spirit Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Mayagüez from Chicago O'Hare Intl Airport according to our data. Spirit Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago O'Hare Intl Airport to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Mayagüez (ORD to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Mayagüez

Fastest flight time

11h 28m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Mayagüez takes 11h 28m
There are no direct flights from Chicago O'Hare Intl Airport to Mayagüez. There are no popular flight routes from Chicago O'Hare Intl Airport to Mayagüez.
Search flight deals

  • How far is Chicago O'Hare Intl to Mayagüez Eugenio M De Hostos by plane?

    The straight-line distance from Chicago O'Hare Intl to Mayagüez Eugenio M De Hostos is 2045.8 mi. Flights usually cover this in 11h 28m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Mayagüez?

Finding the right flight to Mayagüez from Chicago is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mayagüez quick and easy, saving you time and money.

Can I find flights from Chicago to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Mayagüez?

momondo helps you find the best flight between Chicago and Mayagüez by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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