Cheap flights from North Carolina to South America from $139

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to South America departing on 7/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
4:21 pm - 9:40 am
RDU
-
MDE
18h 19m
1 stop
Copa Airlines Logo
4:30 pm - 2:28 pm
MDE
-
RDU
20h 58m
1 stop
$299Copa Airlines
อา., ก.ย. 6 - ส., ก.ย. 12
Copa Airlines Logo
4:21 pm - 8:15 am
RDU
-
MDE
16h 54m
1 stop
Copa Airlines Logo
6:20 pm - 2:28 pm
MDE
-
RDU
19h 08m
1 stop
$314Copa Airlines
ศ., ก.ย. 11 - อา., ก.ย. 13
United Airlines Logo
6:00 am - 9:10 pm
RDU
-
MDE
16h 10m
2 stops
United Airlines Logo
9:45 am - 2:01 pm
MDE
-
RDU
27h 16m
2 stops
$316United Airlines
อ., มิ.ย. 16 - ศ., ก.ค. 3
United Airlines Logo
6:15 am - 9:10 pm
RDU
-
MDE
39h 55m
2 stops
United Airlines Logo
9:45 am - 2:01 pm
MDE
-
RDU
27h 16m
2 stops
$329United Airlines
ส., มิ.ย. 20 - ศ., ก.ค. 3
American Airlines Logo
8:04 pm - 12:35 pm
RDU
-
CTG
17h 31m
2 stops
American Airlines Logo
3:15 pm - 10:38 am
CTG
-
RDU
18h 23m
2 stops
$330American Airlines
อ., ก.ค. 28 - พฤ., ส.ค. 6
American Airlines Logo
8:04 pm - 12:35 pm
RDU
-
CTG
17h 31m
2 stops
American Airlines Logo
3:15 pm - 10:40 am
CTG
-
RDU
18h 25m
1 stop
$338American Airlines
อ., ก.ค. 28 - พฤ., ส.ค. 6
Delta Logo
6:15 pm - 1:05 pm
RDU
-
CTG
19h 50m
1 stop
Delta Logo
2:30 pm - 12:42 am
CTG
-
RDU
9h 12m
1 stop
$347Delta
ศ., ส.ค. 28 - ส., ก.ย. 5
LATAM Airlines Logo
7:00 am - 5:50 pm
RDU
-
BOG
11h 50m
2 stops
LATAM Airlines Logo
11:00 am - 8:15 pm
BOG
-
RDU
8h 15m
1 stop
$360LATAM Airlines
อา., ก.ย. 6 - ส., ก.ย. 19
LATAM Airlines Logo
7:45 am - 1:40 pm
RDU
-
BOG
6h 55m
1 stop
LATAM Airlines Logo
8:40 am - 8:15 pm
BOG
-
RDU
10h 35m
1 stop
$364LATAM Airlines
อ., ก.ย. 8 - พฤ., ก.ย. 24
Delta Logo
5:15 am - 7:15 pm
RDU
-
BOG
15h 00m
1 stop
Delta Logo
2:55 pm - 12:25 am
BOG
-
RDU
8h 30m
1 stop
$365Delta
พฤ., ก.ย. 17 - อา., ก.ย. 20

Copa Airlines flights from North Carolina to South America

Our best Copa Airlines deals on North Carolina to South America flight tickets
Copa Airlines
Sep 6
RDU4:21 pmRaleigh-Durham
18h 19m
1 stop
MDE9:40 amMedellín Jose Maria Cordova Intl
Sep 12
MDE4:30 pmMedellín Jose Maria Cordova Intl
20h 58m
1 stop
RDU2:28 pmRaleigh-Durham
$299
Copa Airlines
Sep 11
RDU4:21 pmRaleigh-Durham
16h 54m
1 stop
MDE8:15 amMedellín Jose Maria Cordova Intl
Sep 13
MDE6:20 pmMedellín Jose Maria Cordova Intl
19h 08m
1 stop
RDU2:28 pmRaleigh-Durham
$314
Copa Airlines
Jun 5
RDU4:20 pmRaleigh-Durham
19h 35m
1 stop
MDE10:55 amMedellín Jose Maria Cordova Intl
Jun 13
MDE12:40 pmMedellín Jose Maria Cordova Intl
24h 49m
1 stop
RDU2:29 pmRaleigh-Durham
$326

LATAM Airlines flights from North Carolina to South America

Our best LATAM Airlines deals on North Carolina to South America flight tickets
LATAM Airlines
Sep 6
RDU7:00 amRaleigh-Durham
11h 50m
2 stops
BOG5:50 pmBogotá El Dorado
Sep 19
BOG11:00 amBogotá El Dorado
8h 15m
1 stop
RDU8:15 pmRaleigh-Durham
$360
LATAM Airlines
Sep 8
RDU7:45 amRaleigh-Durham
6h 55m
1 stop
BOG1:40 pmBogotá El Dorado
Sep 24
BOG8:40 amBogotá El Dorado
10h 35m
1 stop
RDU8:15 pmRaleigh-Durham
$364
LATAM Airlines
Sep 11
RDU8:20 amRaleigh-Durham
12h 50m
1 stop
BOG8:10 pmBogotá El Dorado
Sep 28
BOG10:35 amBogotá El Dorado
12h 50m
2 stops
RDU12:25 amRaleigh-Durham
$369

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated มิถุนายน 4, 2026.
Use the filters below to find and compare flights from North Carolina to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

อา. 9/6

4:21 pm-9:40 am

1 stop18h 19m

Medellín Jose Maria Cordova Intl

ส. 9/12

4:30 pm-2:28 pm

1 stop20h 58m

$299

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

ศ. 9/11

4:21 pm-8:15 am

1 stop16h 54m

Medellín Jose Maria Cordova Intl

อา. 9/13

6:20 pm-2:28 pm

1 stop19h 08m

$314

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

อ. 6/16

6:00 am-9:10 pm

2 stops16h 10m

Medellín Jose Maria Cordova Intl

ศ. 7/3

9:45 am-2:01 pm

2 stops27h 16m

$316

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

ส. 6/20

6:15 am-9:10 pm

2 stops39h 55m

Medellín Jose Maria Cordova Intl

ศ. 7/3

9:45 am-2:01 pm

2 stops27h 16m

$329

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

อ. 7/28

8:04 pm-12:35 pm

2 stops17h 31m

Cartagena Rafael Nunez

พฤ. 8/6

3:15 pm-10:38 am

2 stops18h 23m

$330

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

อ. 7/28

8:04 pm-12:35 pm

2 stops17h 31m

Cartagena Rafael Nunez

พฤ. 8/6

3:15 pm-10:40 am

1 stop18h 25m

$338

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

ศ. 8/28

6:15 pm-1:05 pm

1 stop19h 50m

Cartagena Rafael Nunez

ส. 9/5

2:30 pm-12:42 am

1 stop9h 12m

$347

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

อา. 9/6

7:00 am-5:50 pm

2 stops11h 50m

Bogotá El Dorado

ส. 9/19

11:00 am-8:15 pm

1 stop8h 15m

$360
Quickest round-trip

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

อ. 9/8

7:45 am-1:40 pm

1 stop6h 55m

Bogotá El Dorado

พฤ. 9/24

8:40 am-8:15 pm

1 stop10h 35m

$364

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

พฤ. 9/17

5:15 am-7:15 pm

1 stop15h 00m

Bogotá El Dorado

อา. 9/20

2:55 pm-12:25 am

1 stop8h 30m

$365

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from North Carolina to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from North Carolina to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $577. If you aren’t able to travel during the month of February, then book flights to South America from North Carolina during June instead. Flights to South America in June, while not as cheap as those in February, still average around $670.

How far in advance should I book a flight from North Carolina to South America?

You are more likely to see cheaper flights to South America from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $581 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from North Carolina for as low as $517 on momondo.

Can stopping save me money on North Carolina to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a North Carolina to South America flight.

Cheap North Carolina to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to South America

Fastest flight time

5h 41m

Direct flights

None
The fastest flight from North Carolina to South America takes 5h 41m
There are no direct flights from North Carolina to South America. There are no popular flight routes from North Carolina to South America.

Frequently asked questions about flying from North Carolina to South America

  • When did momondo last update prices for flights from North Carolina to South America?

    Prices for flights from North Carolina to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from North Carolina to South America?

  • How old do you have to be to fly from North Carolina to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from North Carolina to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from North Carolina to South America

Compare and see reviews for airlines that fly from North Carolina to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $102Free CancellationRating
7.8
8,395 reviews
Search Delta flights
LATAM AirlinesPriceFrom $143Free CancellationRating
7.4
1,919 reviews
Search LATAM Airlines flights
JetBluePriceFrom $197Free CancellationRating
7.1
2,982 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $216Free CancellationRating
7.5
1,568 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,641 reviews
Search American Airlines flights
United AirlinesPriceFrom $304Free CancellationRating
7.4
9,773 reviews
Search United Airlines flights
GOLPriceFrom $628Free CancellationRating
7.3
1,224 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to South America?

It is quick and easy to find North Carolina to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from North Carolina to South America with flexible booking policies on momondo?

Flights from North Carolina to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from North Carolina to South America?

Once you have performed a search for North Carolina to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from North Carolina to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for North Carolina to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
ส. 7/4
ส. 7/11

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