Cheap flights from Myrtle Beach to Santiago from $639

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Santiago departing on 3/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
9:49 pm - 2:40 pm
MYR
-
SCL
39h 51m
3 stops
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$639Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
Multiple Airlines Logo
9:49 pm - 6:40 am
MYR
-
SCL
31h 51m
3 stops
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$647Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
Multiple Airlines Logo
9:49 pm - 2:40 pm
MYR
-
SCL
39h 51m
3 stops
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$716Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
Multiple Airlines Logo
9:49 pm - 6:40 am
MYR
-
SCL
31h 51m
3 stops
Multiple Airlines Logo
3:37 pm - 5:33 pm
SCL
-
MYR
26h 56m
3 stops
$727Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
Multiple Airlines Logo
9:49 pm - 6:40 am
MYR
-
SCL
31h 51m
3 stops
Multiple Airlines Logo
3:37 pm - 5:33 pm
SCL
-
MYR
26h 56m
3 stops
$733Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
Multiple Airlines Logo
9:49 pm - 2:40 pm
MYR
-
SCL
39h 51m
3 stops
Multiple Airlines Logo
11:24 am - 8:48 pm
SCL
-
MYR
34h 24m
3 stops
$766Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
Multiple Airlines Logo
3:29 pm - 11:15 am
MYR
-
SCL
18h 46m
2 stops
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$815Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
Multiple Airlines Logo
9:49 pm - 5:55 am
MYR
-
SCL
31h 06m
1 stop
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$838Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
Multiple Airlines Logo
9:49 pm - 5:55 am
MYR
-
SCL
31h 06m
1 stop
Multiple Airlines Logo
11:24 am - 5:33 pm
SCL
-
MYR
31h 09m
2 stops
$839Multiple Airlines
Sat, Mar 14 - Fri, Mar 20
LATAM Airlines Logo
6:54 pm - 7:40 am
MYR
-
SCL
11h 46m
1 stop
LATAM Airlines Logo
12:20 am - 9:33 am
SCL
-
MYR
34h 13m
2 stops
$900LATAM Airlines
Fri, Mar 20 - Thu, Mar 26

LATAM Airlines flights from Myrtle Beach to Santiago

Our best LATAM Airlines deals on Myrtle Beach to Santiago flight tickets
LATAM Airlines
Mar 20
MYR6:54 pmMyrtle Beach Intl
11h 46m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 26
SCL12:20 amSantiago Arturo Merino Benitez
34h 13m
2 stops
MYR9:33 amMyrtle Beach Intl
$900
LATAM Airlines
Mar 14
MYR6:00 amMyrtle Beach Intl
22h 35m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 19
SCL12:20 amSantiago Arturo Merino Benitez
24h 44m
2 stops
MYR12:04 amMyrtle Beach Intl
$920
LATAM Airlines
Mar 14
MYR4:00 pmMyrtle Beach Intl
14h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 20
SCL10:10 pmSantiago Arturo Merino Benitez
12h 23m
1 stop
MYR9:33 amMyrtle Beach Intl
$935

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-2:40 pm

3 stops39h 51m

Santiago Arturo Merino Benitez

Fri 3/20

11:24 am-5:33 pm

2 stops31h 09m

$639

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-6:40 am

3 stops31h 51m

Santiago Arturo Merino Benitez

Fri 3/20

11:24 am-5:33 pm

2 stops31h 09m

$647

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/20

9:49 pm-2:40 pm

3 stops39h 51m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-5:33 pm

2 stops31h 09m

$716

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-6:40 am

3 stops31h 51m

Santiago Arturo Merino Benitez

Fri 3/20

3:37 pm-5:33 pm

3 stops26h 56m

$727

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-6:40 am

3 stops31h 51m

Santiago Arturo Merino Benitez

Fri 3/20

3:37 pm-5:33 pm

3 stops26h 56m

$733

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/20

9:49 pm-2:40 pm

3 stops39h 51m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-8:48 pm

3 stops34h 24m

$766

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/20

3:29 pm-11:15 am

2 stops18h 46m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-5:33 pm

2 stops31h 09m

$815

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-5:55 am

1 stop31h 06m

Santiago Arturo Merino Benitez

Fri 3/20

11:24 am-5:33 pm

2 stops31h 09m

$838

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

9:49 pm-5:55 am

1 stop31h 06m

Santiago Arturo Merino Benitez

Fri 3/20

11:24 am-5:33 pm

2 stops31h 09m

$839

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/20

6:54 pm-7:40 am

1 stop11h 46m

Santiago Arturo Merino Benitez

Thu 3/26

12:20 am-9:33 am

2 stops34h 13m

$900

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Myrtle Beach to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to Santiago flights?

You could potentially save up to 13% on your flight if you consider stops on a Myrtle Beach to Santiago flight.

When to book flights from Myrtle Beach to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santiago (MYR to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santiago

Fastest flight time

31h 51m

Direct flights

None
The fastest flight from Myrtle Beach to Santiago takes 31h 51m
There are no direct flights from Myrtle Beach to Santiago. There are no popular flight routes from Myrtle Beach to Santiago.
  • How far is Myrtle Beach Intl to Santiago Arturo Merino Benitez by plane?

    The distance between Myrtle Beach Intl and Santiago Arturo Merino Benitez is about 4666.1 mi. Typically, this will take 31h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Santiago for you.

Can I find flights from Myrtle Beach to Santiago with flexible booking policies on momondo?

Flights from Myrtle Beach to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Santiago?

Once all potential Myrtle Beach to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sat 3/7
Sat 3/14

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