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Cheap flights from Myrtle Beach to Santiago from $732

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Santiago departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
2:19 pm - 7:40 am
MYR
-
SCL
15h 21m1 stop
LATAM Airlines Logo
9:30 pm - 9:46 am
SCL
-
MYR
14h 16m1 stop
$732LATAM Airlines
Mon, Jan 12 - Mon, Jan 19
LATAM Airlines Logo
2:19 pm - 2:05 pm
MYR
-
SCL
21h 46m2 stops
LATAM Airlines Logo
9:30 pm - 3:10 pm
SCL
-
MYR
19h 40m1 stop
$739LATAM Airlines
Mon, Jan 12 - Mon, Jan 19
Delta Logo
6:00 am - 6:35 am
MYR
-
SCL
22h 35m2 stops
Delta Logo
12:20 am - 11:41 pm
SCL
-
MYR
25h 21m2 stops
$756Delta
Mon, Jan 12 - Sun, Jan 18
LATAM Airlines Logo
10:23 am - 6:35 am
MYR
-
SCL
19h 12m2 stops
LATAM Airlines Logo
10:10 pm - 9:38 am
SCL
-
MYR
12h 28m1 stop
$794LATAM Airlines
Sat, Mar 14 - Sat, Mar 21
LATAM Airlines Logo
10:23 am - 6:35 am
MYR
-
SCL
19h 12m2 stops
LATAM Airlines Logo
11:25 pm - 6:08 pm
SCL
-
MYR
19h 43m2 stops
$799LATAM Airlines
Sat, Mar 14 - Sat, Mar 21
LATAM Airlines Logo
2:21 pm - 7:40 am
MYR
-
SCL
15h 19m1 stop
LATAM Airlines Logo
10:10 pm - 9:38 am
SCL
-
MYR
12h 28m1 stop
$808LATAM Airlines
Fri, Mar 6 - Sat, Mar 14
LATAM Airlines Logo
2:21 pm - 7:40 am
MYR
-
SCL
15h 19m1 stop
LATAM Airlines Logo
4:35 pm - 11:59 pm
SCL
-
MYR
32h 24m2 stops
$822LATAM Airlines
Fri, Mar 6 - Sat, Mar 14
Delta Logo
6:58 pm - 7:40 am
MYR
-
SCL
11h 42m1 stop
Delta Logo
10:10 pm - 9:38 am
SCL
-
MYR
12h 28m1 stop
$836Delta
Sat, Mar 14 - Sat, Mar 21
Delta Logo
6:00 am - 6:55 am
MYR
-
SCL
22h 55m2 stops
Delta Logo
12:20 pm - 9:38 am
SCL
-
MYR
22h 18m2 stops
$841Delta
Fri, Mar 6 - Sat, Mar 14
LATAM Airlines Logo
6:00 am - 5:35 am
MYR
-
SCL
22h 35m2 stops
LATAM Airlines Logo
8:25 am - 1:32 pm
SCL
-
MYR
30h 07m3 stops
$932LATAM Airlines
Sat, Mar 14 - Sat, Mar 21

LATAM Airlines flights from Myrtle Beach to Santiago

Our best LATAM Airlines deals on Myrtle Beach to Santiago flight tickets
LATAM Airlines
Jan 12
MYR2:19 pmMyrtle Beach Intl
15h 21m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Jan 19
SCL9:30 pmSantiago Arturo Merino Benitez
14h 16m
1 stop
MYR9:46 amMyrtle Beach Intl
$732
Find similar
LATAM Airlines
Jan 12
MYR2:19 pmMyrtle Beach Intl
21h 46m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
Jan 19
SCL9:30 pmSantiago Arturo Merino Benitez
19h 40m
1 stop
MYR3:10 pmMyrtle Beach Intl
$739
Find similar
LATAM Airlines
Mar 14
MYR10:23 amMyrtle Beach Intl
19h 12m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Mar 21
SCL10:10 pmSantiago Arturo Merino Benitez
12h 28m
1 stop
MYR9:38 amMyrtle Beach Intl
$794
Find similar

Delta flights from Myrtle Beach to Santiago

Our best Delta deals on Myrtle Beach to Santiago flight tickets
Delta
Jan 12
MYR6:00 amMyrtle Beach Intl
22h 35m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Jan 18
SCL12:20 amSantiago Arturo Merino Benitez
25h 21m
2 stops
MYR11:41 pmMyrtle Beach Intl
$756
Find similar
Delta
Mar 14
MYR6:58 pmMyrtle Beach Intl
11h 42m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 21
SCL10:10 pmSantiago Arturo Merino Benitez
12h 28m
1 stop
MYR9:38 amMyrtle Beach Intl
$836
Find similar
Delta
Mar 6
MYR6:00 amMyrtle Beach Intl
22h 55m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Mar 14
SCL12:20 pmSantiago Arturo Merino Benitez
22h 18m
2 stops
MYR9:38 amMyrtle Beach Intl
$841
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Mon 1/12

2:19 pm-7:40 am

1 stop15h 21m

Santiago Arturo Merino Benitez

Mon 1/19

9:30 pm-9:46 am

1 stop14h 16m

$732

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Mon 1/12

2:19 pm-2:05 pm

2 stops21h 46m

Santiago Arturo Merino Benitez

Mon 1/19

9:30 pm-3:10 pm

1 stop19h 40m

$739

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Mon 1/12

6:00 am-6:35 am

2 stops22h 35m

Santiago Arturo Merino Benitez

Sun 1/18

12:20 am-11:41 pm

2 stops25h 21m

$756

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

10:23 am-6:35 am

2 stops19h 12m

Santiago Arturo Merino Benitez

Sat 3/21

10:10 pm-9:38 am

1 stop12h 28m

$794

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

10:23 am-6:35 am

2 stops19h 12m

Santiago Arturo Merino Benitez

Sat 3/21

11:25 pm-6:08 pm

2 stops19h 43m

$799

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/6

2:21 pm-7:40 am

1 stop15h 19m

Santiago Arturo Merino Benitez

Sat 3/14

10:10 pm-9:38 am

1 stop12h 28m

$808

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/6

2:21 pm-7:40 am

1 stop15h 19m

Santiago Arturo Merino Benitez

Sat 3/14

4:35 pm-11:59 pm

2 stops32h 24m

$822

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

6:58 pm-7:40 am

1 stop11h 42m

Santiago Arturo Merino Benitez

Sat 3/21

10:10 pm-9:38 am

1 stop12h 28m

$836

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Fri 3/6

6:00 am-6:55 am

2 stops22h 55m

Santiago Arturo Merino Benitez

Sat 3/14

12:20 pm-9:38 am

2 stops22h 18m

$841

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 3/14

6:00 am-5:35 am

2 stops22h 35m

Santiago Arturo Merino Benitez

Sat 3/21

8:25 am-1:32 pm

3 stops30h 07m

$932

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Myrtle Beach to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $856. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,265.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Myrtle Beach to Santiago when you can find flight prices for as low as $856. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,205 per ticket.

Can stopping save me money on Myrtle Beach to Santiago flights?

You could potentially save up to 10% on your flight if you consider stops on a Myrtle Beach to Santiago flight.

When to book flights from Myrtle Beach to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santiago (MYR to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santiago

Fastest flight time

17h 16m

Direct flights

None
The fastest flight from Myrtle Beach to Santiago takes 17h 16m
There are no direct flights from Myrtle Beach to Santiago. There are no popular flight routes from Myrtle Beach to Santiago.
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  • How far is Myrtle Beach Intl to Santiago Arturo Merino Benitez by plane?

    The distance between Myrtle Beach Intl and Santiago Arturo Merino Benitez is about 4666.1 mi. Typically, this will take 17h 16m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Santiago for you.

Can I find flights from Myrtle Beach to Santiago with flexible booking policies on momondo?

Flights from Myrtle Beach to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Santiago?

Once all potential Myrtle Beach to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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