Cheap flights from Missouri to Mexico from $95

If you’re not able to fly to Mexico in September, then August is your next best option. Flight prices from Missouri to Mexico during August average around $113.

The cheapest day to depart on your flight to Mexico is on a Saturday when prices can be found for as low as $573. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $702. These prices are subject to change though, so be sure to set up a Price Alert for flights to Mexico.

Fly from Lambert-St Louis to Cancun for the best Missouri - Mexico flight prices

You are more likely to see cheaper flights to Mexico from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $461 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Missouri for as low as $385 on momondo.

There are 2 cabin classes available to choose from on Missouri to Mexico flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 15% on your flight if you consider stops on a Missouri to Mexico flight.

Avianca, Frontier, and Delta are the most popular carriers operating from Missouri to Mexico

American Airlines, Frontier and United Airlines are the top three most popular airlines that fly to Mexico from Missouri according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 9 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

As of June 2026, there are 3 flights per day flying from Missouri to Mexico. The most common time of day flights depart is 6:00AM, with 96% of flights taking off at noon.

As of June 2026, there are 23 flights per week flying from Missouri to Mexico. The most common day of the week flights depart is Tue, with 22% of flights taking off on this day.