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Cheap flights from Mississippi to Knoxville from $42

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Knoxville departing on 11/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Mississippi to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
1:41 pm - 4:03 pmMEM-TYS
1h 22mnonstop
Allegiant Air Logo
12:50 pm - 1:17 pmTYS-MEM
1h 27mnonstop
$84Allegiant Air
Find Deal
dom., nov. 23 - lun., dic. 1
Allegiant Air Logo
1:41 pm - 4:03 pmMEM-TYS
1h 22mnonstop
Allegiant Air Logo
12:45 pm - 1:12 pmTYS-MEM
1h 27mnonstop
$86Allegiant Air
Find Deal
dom., nov. 23 - vie., nov. 28
Allegiant Air Logo
2:02 pm - 4:24 pmMEM-TYS
1h 22mnonstop
Allegiant Air Logo
12:50 pm - 1:17 pmTYS-MEM
1h 27mnonstop
$91Allegiant Air
Find Deal
vie., nov. 28 - lun., dic. 1
Multiple Airlines Logo
2:07 pm - 4:29 pmMEM-TYS
1h 22mnonstop
Multiple Airlines Logo
6:30 am - 7:12 pmTYS-MEM
13h 42m1 stop
$143Multiple Airlines
Find Deal
lun., dic. 1 - jue., dic. 4
Multiple Airlines Logo
2:02 pm - 4:24 pmMEM-TYS
1h 22mnonstop
Multiple Airlines Logo
6:30 am - 7:12 pmTYS-MEM
13h 42m1 stop
$148Multiple Airlines
Find Deal
vie., nov. 28 - jue., dic. 4
Frontier Logo
8:07 pm - 3:57 pmMEM-TYS
18h 50m1 stop
Frontier Logo
4:52 pm - 3:33 pmTYS-MEM
23h 41m1 stop
$202Frontier
Find Deal
dom., dic. 7 - dom., dic. 14
Delta Logo
7:00 am - 11:07 amMEM-TYS
3h 07m1 stop
Delta Logo
10:05 am - 12:43 pmTYS-MEM
3h 38m1 stop
$209Delta
Find Deal
mié., feb. 18 - sáb., feb. 21
Delta Logo
10:40 am - 3:06 pmJAN-TYS
3h 26m1 stop
Delta Logo
10:05 am - 2:09 pmTYS-JAN
5h 04m1 stop
$239Delta
Find Deal
mié., feb. 18 - sáb., feb. 21
United Airlines Logo
5:15 pm - 11:44 pmGPT-TYS
5h 29m1 stop
United Airlines Logo
7:00 am - 11:17 amTYS-GPT
5h 17m1 stop
$239United Airlines
Find Deal
mié., nov. 5 - dom., nov. 9
United Airlines Logo
11:52 am - 8:09 pmGPT-TYS
7h 17m1 stop
United Airlines Logo
7:00 am - 11:17 amTYS-GPT
5h 17m1 stop
$330United Airlines
Find Deal
jue., nov. 6 - dom., nov. 9

American Airlines flights from Mississippi to Knoxville

Our best American Airlines deals on Mississippi to Knoxville flight tickets
American Airlines
Feb 21
GPT5:25 amGulfport Biloxi Regional
5h 51m
1 stop
TYS12:16 pmKnoxville McGhee Tyson
Feb 24
TYS4:18 pmKnoxville McGhee Tyson
6h 18m
1 stop
GPT9:36 pmGulfport Biloxi Regional
$289
Find similar
American Airlines
Feb 18
BTR6:07 pmBaton Rouge Ryan
4h 33m
1 stop
TYS11:40 pmKnoxville McGhee Tyson
Feb 21
TYS7:18 amKnoxville McGhee Tyson
9h 57m
2 stops
BTR4:15 pmBaton Rouge Ryan
$324
Find similar
American Airlines
Feb 18
BTR10:16 amBaton Rouge Ryan
10h 23m
2 stops
TYS9:39 pmKnoxville McGhee Tyson
Feb 21
TYS7:18 amKnoxville McGhee Tyson
9h 57m
2 stops
BTR4:15 pmBaton Rouge Ryan
$329
Find similar

Delta flights from Mississippi to Knoxville

Our best Delta deals on Mississippi to Knoxville flight tickets
Delta
Feb 18
MEM7:00 amMemphis
3h 07m
1 stop
TYS11:07 amKnoxville McGhee Tyson
Feb 21
TYS10:05 amKnoxville McGhee Tyson
3h 38m
1 stop
MEM12:43 pmMemphis
$209
Find similar
Delta
Feb 18
JAN10:40 amJackson-Evers Intl
3h 26m
1 stop
TYS3:06 pmKnoxville McGhee Tyson
Feb 21
TYS10:05 amKnoxville McGhee Tyson
5h 04m
1 stop
JAN2:09 pmJackson-Evers Intl
$239
Find similar
Delta
Dec 6
MEM12:48 pmMemphis
5h 10m
1 stop
TYS6:58 pmKnoxville McGhee Tyson
Dec 7
TYS5:40 amKnoxville McGhee Tyson
3h 51m
1 stop
MEM8:31 amMemphis
$249
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Mississippi to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

dom. 11/23

1:41 pm-4:03 pm

Nonstop1h 22m

Knoxville McGhee Tyson

lun. 12/1

12:50 pm-1:17 pm

Nonstop1h 27m

$84

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

dom. 11/23

1:41 pm-4:03 pm

Nonstop1h 22m

Knoxville McGhee Tyson

vie. 11/28

12:45 pm-1:12 pm

Nonstop1h 27m

$86

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

vie. 11/28

2:02 pm-4:24 pm

Nonstop1h 22m

Knoxville McGhee Tyson

lun. 12/1

12:50 pm-1:17 pm

Nonstop1h 27m

$91

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

lun. 12/1

2:07 pm-4:29 pm

Nonstop1h 22m

Knoxville McGhee Tyson

jue. 12/4

6:30 am-7:12 pm

1 stop13h 42m

$143

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

vie. 11/28

2:02 pm-4:24 pm

Nonstop1h 22m

Knoxville McGhee Tyson

jue. 12/4

6:30 am-7:12 pm

1 stop13h 42m

$148

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

dom. 12/7

8:07 pm-3:57 pm

1 stop18h 50m

Knoxville McGhee Tyson

dom. 12/14

4:52 pm-3:33 pm

1 stop23h 41m

$202

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

mié. 2/18

7:00 am-11:07 am

1 stop3h 07m

Knoxville McGhee Tyson

sáb. 2/21

10:05 am-12:43 pm

1 stop3h 38m

$209

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

mié. 2/18

10:40 am-3:06 pm

1 stop3h 26m

Knoxville McGhee Tyson

sáb. 2/21

10:05 am-2:09 pm

1 stop5h 04m

$239

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

mié. 11/5

5:15 pm-11:44 pm

1 stop5h 29m

Knoxville McGhee Tyson

dom. 11/9

7:00 am-11:17 am

1 stop5h 17m

$239

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

jue. 11/6

11:52 am-8:09 pm

1 stop7h 17m

Knoxville McGhee Tyson

dom. 11/9

7:00 am-11:17 am

1 stop5h 17m

$330

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Mississippi to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Mississippi, with most prices found around $248. If you aren’t able to travel during the month of July, then book flights to Knoxville from Mississippi during January instead. Flights to Knoxville in January, while not as cheap as those in July, still average around $278.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Mississippi to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $288. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Mississippi to Knoxville for around $623.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Mississippi to Knoxville when you can find flight prices for as low as $390. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $540.

Can stopping save me money on Mississippi to Knoxville flights?

You could potentially save up to 49% on your flight if you consider stops on a Mississippi to Knoxville flight.

Cheap Mississippi to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Knoxville

Fastest flight time

1h 19m

Direct flights

Mon and Fri

Airports in Knoxville

1 airport
The fastest flight from Mississippi to Knoxville takes 1h 19m
Direct flights go from Mississippi to Knoxville on Monday and Friday. There are no airlines offering direct flights.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Knoxville McGhee Tyson Airport?

    Prices for flights from Mississippi to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Mississippi to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Knoxville

Compare and see reviews for airlines that fly from Mississippi to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $178Free CancellationRating
7.9
7,982 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Knoxville?

It is quick and easy to find Mississippi to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Mississippi to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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