Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Mississippi to Knoxville from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Knoxville departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Mississippi to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
8:05 am - 10:24 pm
MEM
-
TYS
13h 19m
1 stop
Allegiant Air Logo
9:40 pm - 5:49 pm
TYS
-
MEM
21h 09m
1 stop
$207Allegiant Air
Mon, May 4 - Thu, May 7
Allegiant Air Logo
8:05 am - 10:24 pm
MEM
-
TYS
13h 19m
1 stop
Allegiant Air Logo
1:14 pm - 6:10 pm
TYS
-
MEM
5h 56m
1 stop
$221Allegiant Air
Mon, Apr 13 - Thu, Apr 16
American Airlines Logo
3:23 pm - 10:24 pm
MEM
-
TYS
6h 01m
1 stop
American Airlines Logo
5:00 am - 8:18 am
TYS
-
MEM
4h 18m
1 stop
$233American Airlines
Wed, Apr 22 - Wed, Apr 29
Multiple Airlines Logo
8:05 am - 10:24 pm
MEM
-
TYS
13h 19m
1 stop
Multiple Airlines Logo
1:15 pm - 3:40 pm
TYS
-
MEM
27h 25m
1 stop
$246Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
4:53 pm - 11:56 pm
BTR
-
TYS
6h 03m
1 stop
American Airlines Logo
5:11 pm - 10:20 pm
TYS
-
BTR
6h 09m
1 stop
$291American Airlines
Tue, May 5 - Tue, May 12
Delta Logo
7:08 pm - 11:54 pm
BTR
-
TYS
3h 46m
1 stop
Delta Logo
4:38 pm - 9:56 pm
TYS
-
BTR
6h 18m
1 stop
$310Delta
Tue, Apr 21 - Tue, Apr 28
Delta Logo
5:57 pm - 11:57 pm
GPT
-
TYS
5h 00m
1 stop
Delta Logo
5:40 am - 9:24 am
TYS
-
GPT
4h 44m
1 stop
$319Delta
Tue, Apr 7 - Mon, Apr 13
United Airlines Logo
2:00 pm - 9:30 pm
GPT
-
TYS
6h 30m
1 stop
United Airlines Logo
7:15 am - 1:26 pm
TYS
-
GPT
7h 11m
1 stop
$379United Airlines
Sat, Aug 22 - Wed, Aug 26
United Airlines Logo
12:00 pm - 6:05 pm
JAN
-
TYS
5h 05m
1 stop
United Airlines Logo
3:25 pm - 9:18 pm
TYS
-
JAN
6h 53m
1 stop
$407United Airlines
Sat, Aug 22 - Tue, Aug 25
Multiple Airlines Logo
9:40 am - 10:51 pm
GPT
-
TYS
12h 11m
1 stop
Multiple Airlines Logo
4:28 pm - 9:00 am
TYS
-
GPT
17h 32m
2 stops
$611Multiple Airlines
Fri, Apr 17 - Sun, Apr 19

Allegiant Air flights from Mississippi to Knoxville

Our best Allegiant Air deals on Mississippi to Knoxville flight tickets
Allegiant Air
May 4
MEM8:05 amMemphis
13h 19m
1 stop
TYS10:24 pmKnoxville McGhee Tyson
May 7
TYS9:40 pmKnoxville McGhee Tyson
21h 09m
1 stop
MEM5:49 pmMemphis
$207
Allegiant Air
Apr 13
MEM8:05 amMemphis
13h 19m
1 stop
TYS10:24 pmKnoxville McGhee Tyson
Apr 16
TYS1:14 pmKnoxville McGhee Tyson
5h 56m
1 stop
MEM6:10 pmMemphis
$221
Allegiant Air
May 7
MEM7:05 pmMemphis
25h 43m
1 stop
TYS9:48 pmKnoxville McGhee Tyson
May 10
TYS1:14 pmKnoxville McGhee Tyson
6h 01m
1 stop
MEM6:15 pmMemphis
$223

American Airlines flights from Mississippi to Knoxville

Our best American Airlines deals on Mississippi to Knoxville flight tickets
American Airlines
Apr 22
MEM3:23 pmMemphis
6h 01m
1 stop
TYS10:24 pmKnoxville McGhee Tyson
Apr 29
TYS5:00 amKnoxville McGhee Tyson
4h 18m
1 stop
MEM8:18 amMemphis
$233
American Airlines
May 5
BTR4:53 pmBaton Rouge Ryan
6h 03m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
May 12
TYS5:11 pmKnoxville McGhee Tyson
6h 09m
1 stop
BTR10:20 pmBaton Rouge Ryan
$291
American Airlines
Apr 26
MEM5:00 amMemphis
5h 15m
1 stop
TYS11:15 amKnoxville McGhee Tyson
Apr 28
TYS5:00 amKnoxville McGhee Tyson
5h 14m
1 stop
MEM9:14 amMemphis
$295

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Mississippi to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

Mon 5/4

8:05 am-10:24 pm

1 stop13h 19m

Knoxville McGhee Tyson

Thu 5/7

9:40 pm-5:49 pm

1 stop21h 09m

$207

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

Mon 4/13

8:05 am-10:24 pm

1 stop13h 19m

Knoxville McGhee Tyson

Thu 4/16

1:14 pm-6:10 pm

1 stop5h 56m

$221

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

Wed 4/22

3:23 pm-10:24 pm

1 stop6h 01m

Knoxville McGhee Tyson

Wed 4/29

5:00 am-8:18 am

1 stop4h 18m

$233

MemphisKnoxville

MEM - TYS

MEMTYS

Memphis

Fri 4/24

8:05 am-10:24 pm

1 stop13h 19m

Knoxville McGhee Tyson

Mon 4/27

1:15 pm-3:40 pm

1 stop27h 25m

$246

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 5/5

4:53 pm-11:56 pm

1 stop6h 03m

Knoxville McGhee Tyson

Tue 5/12

5:11 pm-10:20 pm

1 stop6h 09m

$291

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 4/21

7:08 pm-11:54 pm

1 stop3h 46m

Knoxville McGhee Tyson

Tue 4/28

4:38 pm-9:56 pm

1 stop6h 18m

$310
Quickest round-trip

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Tue 4/7

5:57 pm-11:57 pm

1 stop5h 00m

Knoxville McGhee Tyson

Mon 4/13

5:40 am-9:24 am

1 stop4h 44m

$319

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Sat 8/22

2:00 pm-9:30 pm

1 stop6h 30m

Knoxville McGhee Tyson

Wed 8/26

7:15 am-1:26 pm

1 stop7h 11m

$379

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 8/22

12:00 pm-6:05 pm

1 stop5h 05m

Knoxville McGhee Tyson

Tue 8/25

3:25 pm-9:18 pm

1 stop6h 53m

$407

GulfportKnoxville

GPT - TYS

GPTTYS

Gulfport Biloxi Regional

Fri 4/17

9:40 am-10:51 pm

1 stop12h 11m

Knoxville McGhee Tyson

Sun 4/19

4:28 pm-9:00 am

2 stops17h 32m

$611

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Mississippi to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Mississippi, with most prices found around $248. If you aren’t able to travel during the month of July, then book flights to Knoxville from Mississippi during April instead. Flights to Knoxville in April, while not as cheap as those in July, still average around $266.

Can stopping save me money on Mississippi to Knoxville flights?

You could potentially save up to 27% on your flight if you consider stops on a Mississippi to Knoxville flight.

Cheap Mississippi to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Knoxville

Fastest flight time

3h 05m

Direct flights

None
The fastest flight from Mississippi to Knoxville takes 3h 05m
There are no direct flights from Mississippi to Knoxville. There are no popular flight routes from Mississippi to Knoxville.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Knoxville McGhee Tyson Airport?

    Prices for flights from Mississippi to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Mississippi to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Knoxville

Compare and see reviews for airlines that fly from Mississippi to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $153Free CancellationRating
7.1
11,521 reviews
Search American Airlines flights
DeltaPriceFrom $164Free CancellationRating
7.9
8,359 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Knoxville?

It is quick and easy to find Mississippi to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Mississippi to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 4/28
Tue 5/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States