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Cheap flights from Mississippi to Florence from $432

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Florence departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Mississippi to Florence

Cheap one-way flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:15 am - 2:56 pmMEM  Memphis-FLO Florence
5h 41m1 stop Charlotte Douglas
$432American Airlines
Fri, Aug 28
American Airlines Logo
10:26 am - 10:59 pmMEM  Memphis-FLO Florence
11h 33m2 stops Chicago O'Hare Intl Charlotte Douglas
$524American Airlines
Fri, Aug 28

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Customize your flight search to find flights from Mississippi to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Mississippi to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest one-way
Quickest one-way

MemphisFlorence

MEM Memphis - FLO Florence

MEMFLO

Memphis

Fri 8/28

8:15 am-2:56 pm

1 stop5h 41m

$432

MemphisFlorence

MEM Memphis - FLO Florence

MEMFLO

Memphis

Fri 8/28

10:26 am-10:59 pm

2 stops11h 33m

$524

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Mississippi to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Florence?

American Airlines is the most popular carrier operating from Mississippi to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Mississippi according to our data. American Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 3 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Mississippi to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Florence, South Carolina

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Mississippi to Florence, South Carolina takes 4h 06m
There are no direct flights from Mississippi to Florence, South Carolina. There are no popular flight routes from Mississippi to Florence, South Carolina.
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Frequently asked questions about flying from Mississippi to Florence, South Carolina

  • When did momondo last update prices for flights from Mississippi to Florence Airport?

    Prices for flights from Mississippi to Florence Airport were last updated today.

  • How old do you have to be to fly from Mississippi to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mississippi to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Florence?

Finding the right flight to Florence from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Mississippi to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Florence?

Once you have performed a search for Mississippi to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Mississippi to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Mississippi. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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