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Cheap flights from Chicago Midway Airport to South America from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to South America departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to South America

Cheap round-trip flights

LATAM Airlines Logo
10:35 am - 7:15 pmMDW-BOG
8h 40m1 stop
LATAM Airlines Logo
2:55 pm - 9:40 amBOG-MDW
18h 45m1 stop
$331LATAM Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
LATAM Airlines Logo
6:00 am - 7:15 pmMDW-BOG
13h 15m1 stop
LATAM Airlines Logo
9:00 am - 10:14 pmBOG-MDW
13h 14m1 stop
$366LATAM Airlines
Find Deal
Thu, Oct 16 - Tue, Oct 21
Delta Logo
1:05 pm - 5:10 amMDW-UIO
15h 05m2 stops
Delta Logo
7:00 pm - 12:01 pmUIO-MDW
18h 01m2 stops
$380Delta
Find Deal
Wed, Jan 21 - Mon, Jan 26
LATAM Airlines Logo
10:35 am - 6:59 pmMDW-UIO
8h 24m1 stop
LATAM Airlines Logo
12:59 am - 9:40 amUIO-MDW
8h 41m1 stop
$419LATAM Airlines
Find Deal
Mon, Oct 6 - Mon, Oct 13
LATAM Airlines Logo
6:00 am - 7:15 pmMDW-BOG
13h 15m1 stop
LATAM Airlines Logo
2:55 pm - 9:40 amBOG-MDW
18h 45m1 stop
$430LATAM Airlines
Find Deal
Wed, Oct 1 - Wed, Oct 8
LATAM Airlines Logo
10:35 am - 6:59 pmMDW-UIO
8h 24m1 stop
LATAM Airlines Logo
7:08 pm - 10:14 pmUIO-MDW
27h 06m2 stops
$433LATAM Airlines
Find Deal
Mon, Oct 6 - Tue, Oct 14
LATAM Airlines Logo
6:00 am - 1:40 pmMDW-BOG
7h 40m1 stop
LATAM Airlines Logo
9:00 am - 10:14 pmBOG-MDW
13h 14m1 stop
$446LATAM Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
Delta Logo
6:00 am - 7:54 pmMDW-BOG
13h 54m2 stops
Delta Logo
10:55 am - 10:14 pmBOG-MDW
11h 19m2 stops
$457Delta
Find Deal
Tue, Oct 21 - Wed, Oct 29
Delta Logo
6:00 am - 1:40 pmMDW-BOG
7h 40m1 stop
Delta Logo
6:35 pm - 9:40 amBOG-MDW
15h 05m2 stops
$463Delta
Find Deal
Thu, Oct 16 - Mon, Oct 20
Logo
6:20 am - 12:28 amMDW-MDE
18h 08m2 stops
Logo
1:24 am - 11:20 pmMDE-MDW
21h 56m2 stops
$613
Find Deal
Fri, Sep 19 - Sun, Sep 28

LATAM Airlines flights from Chicago Midway Airport to South America

Our best LATAM Airlines deals on Chicago Midway Airport to South America flight tickets
LATAM Airlines
Sep 17
MDW10:35 amChicago Midway
8h 40m
1 stop
BOG7:15 pmBogotá El Dorado
Sep 24
BOG2:55 pmBogotá El Dorado
18h 45m
1 stop
MDW9:40 amChicago Midway
$331
Find similar
LATAM Airlines
Oct 16
MDW6:00 amChicago Midway
13h 15m
1 stop
BOG7:15 pmBogotá El Dorado
Oct 21
BOG9:00 amBogotá El Dorado
13h 14m
1 stop
MDW10:14 pmChicago Midway
$366
Find similar
LATAM Airlines
Oct 6
MDW10:35 amChicago Midway
8h 24m
1 stop
UIO6:59 pmQuito Mariscal Sucr
Oct 13
UIO12:59 amQuito Mariscal Sucr
8h 41m
1 stop
MDW9:40 amChicago Midway
$419
Find similar

Delta flights from Chicago Midway Airport to South America

Our best Delta deals on Chicago Midway Airport to South America flight tickets
Delta
Jan 21
MDW1:05 pmChicago Midway
15h 05m
2 stops
UIO5:10 amQuito Mariscal Sucr
Jan 26
UIO7:00 pmQuito Mariscal Sucr
18h 01m
2 stops
MDW12:01 pmChicago Midway
$380
Find similar
Delta
Oct 21
MDW6:00 amChicago Midway
13h 54m
2 stops
BOG7:54 pmBogotá El Dorado
Oct 29
BOG10:55 amBogotá El Dorado
11h 19m
2 stops
MDW10:14 pmChicago Midway
$457
Find similar
Delta
Oct 16
MDW6:00 amChicago Midway
7h 40m
1 stop
BOG1:40 pmBogotá El Dorado
Oct 20
BOG6:35 pmBogotá El Dorado
15h 05m
2 stops
MDW9:40 amChicago Midway
$463
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Wed 9/17

10:35 am-7:15 pm

1 stop8h 40m

Bogotá El Dorado

Wed 9/24

2:55 pm-9:40 am

1 stop18h 45m

$331

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Thu 10/16

6:00 am-7:15 pm

1 stop13h 15m

Bogotá El Dorado

Tue 10/21

9:00 am-10:14 pm

1 stop13h 14m

$366

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Wed 1/21

1:05 pm-5:10 am

2 stops15h 05m

Quito Mariscal Sucr

Mon 1/26

7:00 pm-12:01 pm

2 stops18h 01m

$380

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Mon 10/6

10:35 am-6:59 pm

1 stop8h 24m

Quito Mariscal Sucr

Mon 10/13

12:59 am-9:40 am

1 stop8h 41m

$419

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Wed 10/1

6:00 am-7:15 pm

1 stop13h 15m

Bogotá El Dorado

Wed 10/8

2:55 pm-9:40 am

1 stop18h 45m

$430

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Mon 10/6

10:35 am-6:59 pm

1 stop8h 24m

Quito Mariscal Sucr

Tue 10/14

7:08 pm-10:14 pm

2 stops27h 06m

$433

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Tue 10/21

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Tue 10/28

9:00 am-10:14 pm

1 stop13h 14m

$446

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Tue 10/21

6:00 am-7:54 pm

2 stops13h 54m

Bogotá El Dorado

Wed 10/29

10:55 am-10:14 pm

2 stops11h 19m

$457

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Thu 10/16

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Mon 10/20

6:35 pm-9:40 am

2 stops15h 05m

$463

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Fri 9/19

6:20 am-12:28 am

2 stops18h 08m

Medellín Jose Maria Cordova Intl

Sun 9/28

1:24 am-11:20 pm

2 stops21h 56m

$613

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago Midway Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Chicago Midway Airport to South America is on a Monday when prices can be found for as low as $488. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to South America for around $633.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Chicago Midway Airport to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $493. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $822 on average. Flights to South America from Chicago Midway Airport in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Chicago Midway Airport to South America flights?

You could potentially save up to 22% on your flight if you consider stops on a Chicago Midway Airport to South America flight.

Cheap Chicago Midway Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to South America

Best Price Found

$164

Fastest flight time

6h 46m

Direct flights

None

Airports in South America

5 airports
The best one-way flight to South America from Chicago Midway Airport in the past 72 hours is $164. The best round-trip flight deal from Chicago Midway Airport to South America found on momondo in the last 72 hours is $331.
The fastest flight from Chicago Midway Airport to South America takes 6h 46m
There are no direct flights from Chicago Midway Airport to South America. Popular non-direct routes for this connection are Chicago Midway Airport - Bogotá El Dorado Airport, Chicago Midway Airport - Quito Mariscal Sucr Airport and Chicago Midway Airport - Medellín Jose Maria Cordova Intl Airport.
There are 5 airports near South America: Lima J Chavez Intl (LIM), Cartagena Rafael Nunez (CTG), Quito Mariscal Sucr (UIO), Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)
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  • When did momondo last update prices for flights from Chicago Midway Airport to South America?

    Prices for flights from Chicago Midway Airport to South America refresh daily.

  • How many operators does momondo search for flights from Chicago Midway Airport to South America?

  • How old do you have to be to fly from Chicago Midway Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Chicago Midway Airport to South America

Compare and see reviews for airlines that fly from Chicago Midway Airport to South America with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $348Free CancellationRating
7.5
1,830 reviews
Search LATAM Airlines flights
DeltaPriceFrom $374Free CancellationRating
8.0
7,987 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South America?

Once you have performed a search for Chicago to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $306
Flights to Buenos Airesfrom $565
Flights to Bogotáfrom $180
Flights to Sao Paulofrom $348
Flights to Medellínfrom $155
Flights to Rio de Janeirofrom $429
Flights to Santiagofrom $379
Flights to Cartagenafrom $180
Flights to Quitofrom $321
Flights to Cuscofrom $418
Flights to Califrom $179
Flights to Guayaquilfrom $231