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Cheap flights from Midland to Knoxville from $321

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Midland to Knoxville departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Midland to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
11:45 am - 7:40 pm
MAF
-
TYS
6h 55m
2 stops
Southwest Logo
7:05 am - 2:40 pm
TYS
-
MAF
8h 35m
2 stops
$321Southwest
Wed, Apr 22 - Wed, Apr 29
United Airlines Logo
1:45 pm - 10:29 pm
MAF
-
TYS
7h 44m
1 stop
United Airlines Logo
4:30 pm - 10:15 pm
TYS
-
MAF
6h 45m
1 stop
$338United Airlines
Wed, Apr 22 - Wed, Apr 29
Southwest Logo
6:50 am - 2:20 pm
MAF
-
TYS
6h 30m
1 stop
Southwest Logo
7:05 am - 2:05 pm
TYS
-
MAF
8h 00m
2 stops
$340Southwest
Wed, Apr 22 - Wed, Apr 29
Southwest Logo
11:45 am - 7:40 pm
MAF
-
TYS
6h 55m
2 stops
Southwest Logo
12:45 pm - 11:00 pm
TYS
-
MAF
11h 15m
2 stops
$347Southwest
Tue, May 26 - Wed, Jun 10
Southwest Logo
11:00 am - 7:40 pm
MAF
-
TYS
7h 40m
2 stops
Southwest Logo
2:45 pm - 6:30 pm
TYS
-
MAF
4h 45m
1 stop
$350Southwest
Tue, May 26 - Wed, Jun 10
Southwest Logo
11:00 am - 7:40 pm
MAF
-
TYS
7h 40m
2 stops
Southwest Logo
2:45 pm - 11:00 pm
TYS
-
MAF
9h 15m
2 stops
$355Southwest
Tue, May 26 - Wed, Jun 10
American Airlines Logo
5:00 am - 12:30 pm
MAF
-
TYS
6h 30m
1 stop
American Airlines Logo
4:09 pm - 10:07 pm
TYS
-
MAF
6h 58m
1 stop
$376American Airlines
Mon, May 11 - Fri, May 15
American Airlines Logo
2:15 pm - 11:59 pm
MAF
-
TYS
8h 44m
2 stops
American Airlines Logo
1:20 pm - 7:54 pm
TYS
-
MAF
7h 34m
1 stop
$381American Airlines
Mon, May 11 - Fri, May 15
United Airlines Logo
1:45 pm - 10:29 pm
MAF
-
TYS
7h 44m
1 stop
United Airlines Logo
4:30 pm - 10:15 pm
TYS
-
MAF
6h 45m
1 stop
$391United Airlines
Tue, Apr 14 - Wed, Apr 15
United Airlines Logo
1:45 pm - 11:41 pm
MAF
-
TYS
8h 56m
2 stops
United Airlines Logo
4:30 pm - 10:15 pm
TYS
-
MAF
6h 45m
1 stop
$396United Airlines
Tue, Apr 14 - Wed, Apr 15

United Airlines flights from Midland to Knoxville

Our best United Airlines deals on Midland to Knoxville flight tickets
United Airlines
Apr 22
MAF1:45 pmMidland Intl
7h 44m
1 stop
TYS10:29 pmKnoxville McGhee Tyson
Apr 29
TYS4:30 pmKnoxville McGhee Tyson
6h 45m
1 stop
MAF10:15 pmMidland Intl
$338
United Airlines
Apr 14
MAF1:45 pmMidland Intl
7h 44m
1 stop
TYS10:29 pmKnoxville McGhee Tyson
Apr 15
TYS4:30 pmKnoxville McGhee Tyson
6h 45m
1 stop
MAF10:15 pmMidland Intl
$391
United Airlines
Apr 14
MAF1:45 pmMidland Intl
8h 56m
2 stops
TYS11:41 pmKnoxville McGhee Tyson
Apr 15
TYS4:30 pmKnoxville McGhee Tyson
6h 45m
1 stop
MAF10:15 pmMidland Intl
$396

American Airlines flights from Midland to Knoxville

Our best American Airlines deals on Midland to Knoxville flight tickets
American Airlines
May 11
MAF5:00 amMidland Intl
6h 30m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
May 15
TYS4:09 pmKnoxville McGhee Tyson
6h 58m
1 stop
MAF10:07 pmMidland Intl
$376
American Airlines
May 11
MAF2:15 pmMidland Intl
8h 44m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
May 15
TYS1:20 pmKnoxville McGhee Tyson
7h 34m
1 stop
MAF7:54 pmMidland Intl
$381
American Airlines
May 11
MAF2:15 pmMidland Intl
8h 44m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
May 15
TYS3:58 pmKnoxville McGhee Tyson
9h 08m
2 stops
MAF12:06 amMidland Intl
$445

momondo Fare Finder

 
Customize your flight search to find flights from Midland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Midland to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Wed 4/22

11:45 am-7:40 pm

2 stops6h 55m

Knoxville McGhee Tyson

Wed 4/29

7:05 am-2:40 pm

2 stops8h 35m

$321

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Wed 4/22

1:45 pm-10:29 pm

1 stop7h 44m

Knoxville McGhee Tyson

Wed 4/29

4:30 pm-10:15 pm

1 stop6h 45m

$338

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Wed 4/22

6:50 am-2:20 pm

1 stop6h 30m

Knoxville McGhee Tyson

Wed 4/29

7:05 am-2:05 pm

2 stops8h 00m

$340

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 5/26

11:45 am-7:40 pm

2 stops6h 55m

Knoxville McGhee Tyson

Wed 6/10

12:45 pm-11:00 pm

2 stops11h 15m

$347
Quickest round-trip

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 5/26

11:00 am-7:40 pm

2 stops7h 40m

Knoxville McGhee Tyson

Wed 6/10

2:45 pm-6:30 pm

1 stop4h 45m

$350

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 5/26

11:00 am-7:40 pm

2 stops7h 40m

Knoxville McGhee Tyson

Wed 6/10

2:45 pm-11:00 pm

2 stops9h 15m

$355

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Mon 5/11

5:00 am-12:30 pm

1 stop6h 30m

Knoxville McGhee Tyson

Fri 5/15

4:09 pm-10:07 pm

1 stop6h 58m

$376

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Mon 5/11

2:15 pm-11:59 pm

2 stops8h 44m

Knoxville McGhee Tyson

Fri 5/15

1:20 pm-7:54 pm

1 stop7h 34m

$381

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 4/14

1:45 pm-10:29 pm

1 stop7h 44m

Knoxville McGhee Tyson

Wed 4/15

4:30 pm-10:15 pm

1 stop6h 45m

$391

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 4/14

1:45 pm-11:41 pm

2 stops8h 56m

Knoxville McGhee Tyson

Wed 4/15

4:30 pm-10:15 pm

1 stop6h 45m

$396

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from Midland to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Midland and Knoxville?

When to book flights from Midland to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Midland to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Midland to Knoxville (MAF to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Midland to Knoxville

Fastest flight time

5h 49m

Direct flights

None
The fastest flight from Midland to Knoxville takes 5h 49m
There are no direct flights from Midland to Knoxville. There are no popular flight routes from Midland to Knoxville.
Search flight deals

  • How far is Midland Intl to Knoxville McGhee Tyson by plane?

    A flight from Midland Intl to Knoxville McGhee Tyson will travel around 1073.2 mi. By plane, this route typically takes 5h 49m.

  • When did momondo last update prices for flights from Midland Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Midland Intl Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Midland Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Midland Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Midland Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Midland to Knoxville?

Best airlines flying from Midland to Knoxville

Compare and see reviews for airlines that fly from Midland to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $243Free CancellationRating
7.1
11,481 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Midland to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Midland to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Midland to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Midland on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Midland to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Midland to Knoxville.

I’m not ready to book a flight from Midland to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Midland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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