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Cheap flights from Michigan to Mayagüez from $380

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Michigan to Mayagüez departing on 4/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Michigan to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:42 pm - 12:44 pm
ORD
-
MAZ
23h 02m
2 stops
Multiple Airlines Logo
4:36 pm - 3:08 pm
MAZ
-
ORD
23h 32m
1 stop
$380Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
Multiple Airlines Logo
5:50 am - 6:43 pm
ORD
-
MAZ
11h 53m
2 stops
Multiple Airlines Logo
7:35 am - 3:08 pm
MAZ
-
ORD
8h 33m
1 stop
$382Multiple Airlines
Sat, Apr 18 - Wed, Apr 22
Multiple Airlines Logo
12:42 pm - 9:42 am
ORD
-
MAZ
20h 00m
2 stops
Multiple Airlines Logo
4:36 pm - 3:08 pm
MAZ
-
ORD
23h 32m
1 stop
$436Multiple Airlines
Thu, Apr 16 - Mon, Apr 20
Multiple Airlines Logo
10:00 am - 9:42 am
ORD
-
MAZ
22h 42m
1 stop
Multiple Airlines Logo
4:36 pm - 3:08 pm
MAZ
-
ORD
23h 32m
1 stop
$442Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
Multiple Airlines Logo
10:00 am - 6:43 pm
ORD
-
MAZ
7h 43m
1 stop
Multiple Airlines Logo
7:35 am - 3:08 pm
MAZ
-
ORD
8h 33m
1 stop
$449Multiple Airlines
Sat, Apr 18 - Wed, Apr 22
JetBlue Logo
7:30 am - 6:43 pm
DTW
-
MAZ
11h 13m
2 stops
JetBlue Logo
10:07 am - 10:10 pm
MAZ
-
DTW
12h 03m
2 stops
$593JetBlue
Wed, Apr 29 - Wed, May 6
JetBlue Logo
7:30 am - 6:50 pm
DTW
-
MAZ
11h 20m
2 stops
JetBlue Logo
1:25 pm - 11:58 pm
MAZ
-
DTW
10h 33m
2 stops
$1,437JetBlue
Tue, Jul 7 - Mon, Jul 13
United Airlines Logo
7:00 am - 4:11 pm
DTW
-
MAZ
9h 11m
2 stops
United Airlines Logo
1:25 pm - 10:24 pm
MAZ
-
DTW
32h 59m
2 stops
$1,438United Airlines
Sun, May 24 - Sat, May 30
United Airlines Logo
7:00 am - 4:11 pm
DTW
-
MAZ
9h 11m
2 stops
United Airlines Logo
1:25 pm - 10:24 pm
MAZ
-
DTW
32h 59m
2 stops
$1,479United Airlines
Sun, May 24 - Sat, May 30
United Airlines Logo
7:00 am - 4:11 pm
DTW
-
MAZ
9h 11m
2 stops
United Airlines Logo
1:25 pm - 11:43 pm
MAZ
-
DTW
34h 18m
3 stops
$1,552United Airlines
Sun, May 24 - Sat, May 30

JetBlue flights from Michigan to Mayagüez

Our best JetBlue deals on Michigan to Mayagüez flight tickets
JetBlue
Apr 29
DTW7:30 amDetroit Metropolitan Wayne County
11h 13m
2 stops
MAZ6:43 pmMayagüez Eugenio M De Hostos
May 6
MAZ10:07 amMayagüez Eugenio M De Hostos
12h 03m
2 stops
DTW10:10 pmDetroit Metropolitan Wayne County
$593
JetBlue
May 29
ORD3:27 pmChicago O'Hare Intl
16h 17m
2 stops
MAZ8:44 amMayagüez Eugenio M De Hostos
Jun 6
MAZ7:05 amMayagüez Eugenio M De Hostos
16h 51m
2 stops
ORD10:56 pmChicago O'Hare Intl
$1,176
JetBlue
Jul 7
DTW7:30 amDetroit Metropolitan Wayne County
11h 20m
2 stops
MAZ6:50 pmMayagüez Eugenio M De Hostos
Jul 13
MAZ1:25 pmMayagüez Eugenio M De Hostos
10h 33m
2 stops
DTW11:58 pmDetroit Metropolitan Wayne County
$1,437

United Airlines flights from Michigan to Mayagüez

Our best United Airlines deals on Michigan to Mayagüez flight tickets
United Airlines
Jul 22
ORD2:38 pmChicago O'Hare Intl
24h 11m
1 stop
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jul 26
MAZ1:25 pmMayagüez Eugenio M De Hostos
23h 28m
1 stop
ORD11:53 amChicago O'Hare Intl
$1,132
United Airlines
Jul 22
ORD11:03 amChicago O'Hare Intl
27h 46m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jul 26
MAZ1:25 pmMayagüez Eugenio M De Hostos
34h 50m
2 stops
ORD11:15 pmChicago O'Hare Intl
$1,329
United Airlines
May 24
DTW7:00 amDetroit Metropolitan Wayne County
9h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 30
MAZ1:25 pmMayagüez Eugenio M De Hostos
32h 59m
2 stops
DTW10:24 pmDetroit Metropolitan Wayne County
$1,438

momondo Fare Finder

 
Customize your flight search to find flights from Michigan to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 5, 2026.
Use the filters below to find and compare flights from Michigan to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Fri 4/17

12:42 pm-12:44 pm

2 stops23h 02m

Mayagüez Eugenio M De Hostos

Tue 4/21

4:36 pm-3:08 pm

1 stop23h 32m

$380

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sat 4/18

5:50 am-6:43 pm

2 stops11h 53m

Mayagüez Eugenio M De Hostos

Wed 4/22

7:35 am-3:08 pm

1 stop8h 33m

$382

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Thu 4/16

12:42 pm-9:42 am

2 stops20h 00m

Mayagüez Eugenio M De Hostos

Mon 4/20

4:36 pm-3:08 pm

1 stop23h 32m

$436

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Fri 4/17

10:00 am-9:42 am

1 stop22h 42m

Mayagüez Eugenio M De Hostos

Tue 4/21

4:36 pm-3:08 pm

1 stop23h 32m

$442
Quickest round-trip

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sat 4/18

10:00 am-6:43 pm

1 stop7h 43m

Mayagüez Eugenio M De Hostos

Wed 4/22

7:35 am-3:08 pm

1 stop8h 33m

$449

DetroitMayagüez

DTW - MAZ

DTWMAZ

Detroit Metropolitan Wayne County

Wed 4/29

7:30 am-6:43 pm

2 stops11h 13m

Mayagüez Eugenio M De Hostos

Wed 5/6

10:07 am-10:10 pm

2 stops12h 03m

$593

DetroitMayagüez

DTW - MAZ

DTWMAZ

Detroit Metropolitan Wayne County

Tue 7/7

7:30 am-6:50 pm

2 stops11h 20m

Mayagüez Eugenio M De Hostos

Mon 7/13

1:25 pm-11:58 pm

2 stops10h 33m

$1,437

DetroitMayagüez

DTW - MAZ

DTWMAZ

Detroit Metropolitan Wayne County

Sun 5/24

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Sat 5/30

1:25 pm-10:24 pm

2 stops32h 59m

$1,438

DetroitMayagüez

DTW - MAZ

DTWMAZ

Detroit Metropolitan Wayne County

Sun 5/24

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Sat 5/30

1:25 pm-10:24 pm

2 stops32h 59m

$1,479

DetroitMayagüez

DTW - MAZ

DTWMAZ

Detroit Metropolitan Wayne County

Sun 5/24

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Sat 5/30

1:25 pm-11:43 pm

3 stops34h 18m

$1,552

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Michigan to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Michigan to Mayagüez Eugenio M De Hostos?

JetBlue and United Airlines are the most popular carriers operating from Michigan to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

Spirit Airlines, Delta and American Airlines are the top three most popular airlines that fly to Mayagüez from Michigan according to our data. Spirit Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

Cheap Michigan to Mayagüez flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Michigan to Mayagüez

Fastest flight time

10h 11m

Direct flights

None
The fastest flight from Michigan to Mayagüez takes 10h 11m
There are no direct flights from Michigan to Mayagüez. There are no popular flight routes from Michigan to Mayagüez.
Search flight deals

Frequently asked questions about flying from Michigan to Mayagüez

  • When did momondo last update prices for flights from Michigan to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Michigan to Mayagüez Eugenio M De Hostos Airport are updated daily.

  • How old do you have to be to fly from Michigan to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Michigan to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Michigan to Mayagüez?

It is quick and easy to find Michigan to Mayagüez flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Mayagüez that suits you.

Can I find flights from Michigan to Mayagüez with flexible booking policies on momondo?

All flight searches from Michigan to Mayagüez on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Michigan to Mayagüez?

Once you have performed a search for Michigan to Mayagüez flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Michigan to Mayagüez right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Michigan to Mayagüez flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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