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Cheap flights from Mexico to Des Moines from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico to Des Moines departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Mexico to Des Moines

Recent round-trip flight deals from Mexico to Des Moines

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:05 am - 11:14 pm
MEX
-
DSM
35h 09m
2 stops
Multiple Airlines Logo
10:06 pm - 8:05 pm
DSM
-
MEX
22h 59m
1 stop
$450Multiple Airlines
Thu, Aug 6 - Mon, Aug 17
Multiple Airlines Logo
11:05 am - 10:09 am
MEX
-
DSM
46h 04m
2 stops
Multiple Airlines Logo
10:06 pm - 8:05 pm
DSM
-
MEX
22h 59m
1 stop
$453Multiple Airlines
Tue, Aug 11 - Mon, Aug 17
Multiple Airlines Logo
7:35 pm - 12:55 pm
GDL
-
DSM
40h 20m
2 stops
Multiple Airlines Logo
9:56 pm - 7:54 pm
DSM
-
GDL
22h 58m
1 stop
$497Multiple Airlines
Mon, Jun 22 - Mon, Jun 29
Multiple Airlines Logo
11:00 am - 12:55 pm
MEX
-
DSM
24h 55m
1 stop
Multiple Airlines Logo
2:16 pm - 5:30 pm
DSM
-
MEX
28h 14m
1 stop
$510Multiple Airlines
Tue, Jun 2 - Fri, Jun 5
United Airlines Logo
12:11 pm - 7:25 pm
CUN
-
DSM
7h 14m
1 stop
United Airlines Logo
6:50 pm - 12:02 pm
DSM
-
CUN
17h 12m
2 stops
$519United Airlines
Thu, Jun 4 - Mon, Jun 8
United Airlines Logo
12:11 pm - 7:25 pm
CUN
-
DSM
7h 14m
1 stop
United Airlines Logo
6:50 pm - 2:37 pm
DSM
-
CUN
19h 47m
2 stops
$520United Airlines
Thu, Jun 4 - Mon, Jun 8
Delta Logo
1:42 pm - 10:31 pm
PVR
-
DSM
7h 49m
1 stop
Delta Logo
5:41 am - 12:29 pm
DSM
-
PVR
7h 48m
1 stop
$533Delta
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
5:33 pm - 9:11 am
BJX
-
DSM
14h 38m
1 stop
American Airlines Logo
4:48 pm - 9:50 am
DSM
-
BJX
18h 02m
1 stop
$604American Airlines
Fri, Jun 26 - Fri, Jul 3
Delta Logo
1:41 pm - 10:16 am
PVR
-
DSM
19h 35m
2 stops
Delta Logo
6:03 pm - 12:32 pm
DSM
-
PVR
19h 29m
2 stops
$624Delta
Mon, Jun 1 - Tue, Jun 9
American Airlines Logo
6:35 am - 11:58 pm
BJX
-
DSM
16h 23m
1 stop
American Airlines Logo
6:30 am - 9:48 pm
DSM
-
BJX
16h 18m
1 stop
$637American Airlines
Thu, Jul 9 - Fri, Sep 18

United Airlines flights from Mexico to Des Moines

Our best United Airlines deals on Mexico to Des Moines flight tickets
United Airlines
Jun 4
CUN1:12 pmCancun
9h 28m
1 stop
DSM10:40 pmDes Moines
Jun 8
DSM6:20 amDes Moines
12h 59m
1 stop
CUN7:19 pmCancun
$519
United Airlines
Jun 4
CUN12:11 pmCancun
7h 14m
1 stop
DSM7:25 pmDes Moines
Jun 8
DSM6:50 pmDes Moines
19h 47m
2 stops
CUN2:37 pmCancun
$520
United Airlines
Jun 4
CUN12:11 pmCancun
7h 14m
1 stop
DSM7:25 pmDes Moines
Jun 8
DSM6:20 amDes Moines
12h 59m
1 stop
CUN7:19 pmCancun
$521

American Airlines flights from Mexico to Des Moines

Our best American Airlines deals on Mexico to Des Moines flight tickets
American Airlines
Jun 26
BJX5:33 pmLeón Del Bajio
14h 38m
1 stop
DSM9:11 amDes Moines
Jul 3
DSM4:48 pmDes Moines
18h 02m
1 stop
BJX9:50 amLeón Del Bajio
$604
American Airlines
Aug 7
MEX5:00 amMexico City Benito Juarez
9h 12m
1 stop
DSM3:12 pmDes Moines
Aug 21
DSM5:45 amDes Moines
9h 51m
1 stop
MEX2:36 pmMexico City Benito Juarez
$609
American Airlines
Aug 7
MEX3:36 pmMexico City Benito Juarez
20h 53m
1 stop
DSM1:29 pmDes Moines
Aug 21
DSM4:13 pmDes Moines
5h 38m
1 stop
MEX8:51 pmMexico City Benito Juarez
$621

momondo Fare Finder

 
Customize your flight search to find flights from Mexico to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Mexico to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 8/6

11:05 am-11:14 pm

2 stops35h 09m

Des Moines

Mon 8/17

10:06 pm-8:05 pm

1 stop22h 59m

$450

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 8/11

11:05 am-10:09 am

2 stops46h 04m

Des Moines

Mon 8/17

10:06 pm-8:05 pm

1 stop22h 59m

$453

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Mon 6/22

7:35 pm-12:55 pm

2 stops40h 20m

Des Moines

Mon 6/29

9:56 pm-7:54 pm

1 stop22h 58m

$497

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 6/2

11:00 am-12:55 pm

1 stop24h 55m

Des Moines

Fri 6/5

2:16 pm-5:30 pm

1 stop28h 14m

$510

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 6/4

12:11 pm-7:25 pm

1 stop7h 14m

Des Moines

Mon 6/8

6:50 pm-12:02 pm

2 stops17h 12m

$519

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 6/4

12:11 pm-7:25 pm

1 stop7h 14m

Des Moines

Mon 6/8

6:50 pm-2:37 pm

2 stops19h 47m

$520
Quickest round-trip

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Tue 6/30

1:42 pm-10:31 pm

1 stop7h 49m

Des Moines

Tue 7/7

5:41 am-12:29 pm

1 stop7h 48m

$533

LeónDes Moines

BJX - DSM

BJXDSM

León Del Bajio

Fri 6/26

5:33 pm-9:11 am

1 stop14h 38m

Des Moines

Fri 7/3

4:48 pm-9:50 am

1 stop18h 02m

$604

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Mon 6/1

1:41 pm-10:16 am

2 stops19h 35m

Des Moines

Tue 6/9

6:03 pm-12:32 pm

2 stops19h 29m

$624

LeónDes Moines

BJX - DSM

BJXDSM

León Del Bajio

Thu 7/9

6:35 am-11:58 pm

1 stop16h 23m

Des Moines

Fri 9/18

6:30 am-9:48 pm

1 stop16h 18m

$637

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Mexico to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in June, then March is your next best option. Flight prices from Mexico to Des Moines during March average around $476.

Can stopping save me money on Mexico to Des Moines flights?

You could potentially save up to 18% on your flight if you consider stops on a Mexico to Des Moines flight.

Cheap Mexico to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico to Des Moines

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from Mexico to Des Moines takes 6h 45m
There are no direct flights from Mexico to Des Moines. There are no popular flight routes from Mexico to Des Moines.
Search flight deals

Frequently asked questions about flying from Mexico to Des Moines

  • When did momondo last update prices for flights from Mexico to Des Moines Airport?

    Prices for flights from Mexico to Des Moines Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Mexico to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mexico to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Mexico to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Mexico.

Can I find flights from Mexico to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Mexico on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mexico to Des Moines?

momondo helps you find the best flight between Mexico and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mexico to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mexico to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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