What is the cheapest airline that flies from Memphis to Des Moines?

American Airlines and United Airlines are the most popular carriers operating from Memphis to Des Moines

When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?

Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?

As of September 2025, there are 2 operators available to choose from for flights from Memphis Airport to Des Moines Airport.

How old do you have to be to fly from Memphis Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$147 Cheap Flights from Memphis to Des Moines in 2025

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Find the cheapest flights from Memphis to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

6:00 am - 1:32 pmMEM-DSM

7h 32m1 stop

6:33 pm - 11:20 pmDSM-MEM

4h 47m1 stop

$278Delta

Find Deal

Mon, Nov 24 - Mon, Dec 1

10:40 am - 4:30 pmMEM-DSM

5h 50m1 stop

2:40 pm - 9:56 pmDSM-MEM

7h 16m1 stop

$287Delta

Find Deal

Fri, Oct 31 - Sun, Nov 2

8:26 pm - 8:29 amMEM-DSM

12h 03m1 stop

10:41 am - 9:00 amDSM-MEM

22h 19m1 stop

$292

Find Deal

Fri, Oct 17 - Sun, Oct 19

12:06 pm - 8:40 pmMEM-DSM

8h 34m2 stops

2:16 pm - 8:31 pmDSM-MEM

6h 15m1 stop

$309American Airlines

Find Deal

Fri, Oct 31 - Sun, Nov 2

12:06 pm - 8:40 pmMEM-DSM

8h 34m2 stops

2:16 pm - 8:31 pmDSM-MEM

6h 15m1 stop

$322American Airlines

Find Deal

Fri, Oct 31 - Sun, Nov 2

4:08 pm - 8:34 amMEM-DSM

16h 26m1 stop

10:54 am - 7:19 pmDSM-MEM

8h 25m1 stop

$329

Find Deal

Sun, Oct 26 - Fri, Oct 31

3:15 pm - 9:36 pmMEM-DSM

6h 21m1 stop

3:15 pm - 9:53 pmDSM-MEM

6h 38m1 stop

$338United Airlines

Find Deal

Mon, Mar 2 - Fri, Mar 6

7:30 am - 12:14 pmMEM-DSM

4h 44m1 stop

6:15 am - 2:02 pmDSM-MEM

7h 47m1 stop

$447United Airlines

Find Deal

Thu, Sep 18 - Mon, Sep 22

10:50 am - 11:45 pmMEM-DSM

12h 55m2 stops

8:25 am - 6:25 pmDSM-MEM

10h 00m2 stops

$495Southwest

Find Deal

Sun, Oct 26 - Fri, Oct 31

2:20 pm - 11:35 pmMEM-DSM

9h 15m2 stops

6:35 am - 7:30 pmDSM-MEM

12h 55m2 stops

$503Southwest

Find Deal

Mon, Nov 24 - Mon, Dec 1

American Airlines flights from Memphis to Des Moines

Our best American Airlines deals on Memphis to Des Moines flight tickets

American Airlines

Oct 31

MEM12:06 pmMemphis

8h 34m

2 stops

DSM8:40 pmDes Moines

Nov 2

DSM2:16 pmDes Moines

6h 15m

1 stop

MEM8:31 pmMemphis

$309

Find similar

American Airlines

Oct 31

MEM12:06 pmMemphis

8h 34m

2 stops

DSM8:40 pmDes Moines

Nov 2

DSM2:16 pmDes Moines

6h 15m

1 stop

MEM8:31 pmMemphis

$322

Find similar

American Airlines

Oct 17

MEM3:35 pmMemphis

4h 36m

1 stop

DSM8:11 pmDes Moines

Oct 19

DSM6:22 pmDes Moines

5h 37m

1 stop

MEM11:59 pmMemphis

$333

Find similar

United Airlines flights from Memphis to Des Moines

Our best United Airlines deals on Memphis to Des Moines flight tickets

United Airlines

Mar 2

MEM3:15 pmMemphis

6h 21m

1 stop

DSM9:36 pmDes Moines

Mar 6

DSM3:15 pmDes Moines

6h 38m

1 stop

MEM9:53 pmMemphis

$338

Find similar

United Airlines

Sep 18

MEM7:30 amMemphis

4h 44m

1 stop

DSM12:14 pmDes Moines

Sep 22

DSM6:15 amDes Moines

7h 47m

1 stop

MEM2:02 pmMemphis

$447

Find similar

United Airlines

Sep 18

MEM7:00 amMemphis

7h 17m

1 stop

DSM2:17 pmDes Moines

Sep 22

DSM11:35 amDes Moines

10h 02m

2 stops

MEM9:37 pmMemphis

$452

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 11/24

6:00 am-1:32 pm

1 stop7h 32m

Des Moines

Mon 12/1

6:33 pm-11:20 pm

1 stop4h 47m

$278

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/31

10:40 am-4:30 pm

1 stop5h 50m

Des Moines

Sun 11/2

2:40 pm-9:56 pm

1 stop7h 16m

$287

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/17

8:26 pm-8:29 am

1 stop12h 03m

Des Moines

Sun 10/19

10:41 am-9:00 am

1 stop22h 19m

$292

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/31

12:06 pm-8:40 pm

2 stops8h 34m

Des Moines

Sun 11/2

2:16 pm-8:31 pm

1 stop6h 15m

$309

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/31

12:06 pm-8:40 pm

2 stops8h 34m

Des Moines

Sun 11/2

2:16 pm-8:31 pm

1 stop6h 15m

$322

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 10/26

4:08 pm-8:34 am

1 stop16h 26m

Des Moines

Fri 10/31

10:54 am-7:19 pm

1 stop8h 25m

$329

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 3/2

3:15 pm-9:36 pm

1 stop6h 21m

Des Moines

Fri 3/6

3:15 pm-9:53 pm

1 stop6h 38m

$338

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Thu 9/18

7:30 am-12:14 pm

1 stop4h 44m

Des Moines

Mon 9/22

6:15 am-2:02 pm

1 stop7h 47m

$447

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 10/26

10:50 am-11:45 pm

2 stops12h 55m

Des Moines

Fri 10/31

8:25 am-6:25 pm

2 stops10h 00m

$495

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 11/24

2:20 pm-11:35 pm

2 stops9h 15m

Des Moines

Mon 12/1

6:35 am-7:30 pm

2 stops12h 55m

$503

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Memphis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Memphis to Des Moines is on a Monday. Travelers who choose to depart for Des Moines on a Monday will often find tickets for as low as $266. Flights from Memphis to Des Moines on a Friday will generally be more expensive and average around $363. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Memphis to Des Moines in the morning for as low as $321. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $490. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Memphis to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Memphis to Des Moines (MEM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Des Moines

Direct flights	None

There are no direct flights from Memphis to Des Moines. There are no popular flight routes from Memphis to Des Moines.

Search flight deals

How far is Memphis to Des Moines by plane?
Des Moines is 484.7 mi away from Memphis. In terms of flight time, this usually takes a little over 4h 36m.
When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?
Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?
As of September 2025, there are 2 operators available to choose from for flights from Memphis Airport to Des Moines Airport.
How old do you have to be to fly from Memphis Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Memphis to Des Moines?
Based on momondo bookings for flights between Memphis and Des Moines, the leading airline is American Airlines, making up 66% of the total bookings. Other popular airlines include Delta with 34%.

Best airlines flying from Memphis to Des Moines

Compare and see reviews for airlines that fly from Memphis to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $231	Free Cancellation	Rating 7.9 7,977 reviews		Search Delta flights
American Airlines	PriceFrom $241	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

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Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Des Moines?

It is quick and easy to find Memphis to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Memphis to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Memphis to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Memphis to Des Moines?

Once all potential Memphis to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Memphis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.