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Cheap flights from Memphis to Des Moines from $138

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Memphis to Des Moines departing on 6/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Memphis to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:14 am
MEM
-
DSM
4h 14m
1 stop
Delta Logo
6:03 pm - 10:21 pm
DSM
-
MEM
4h 18m
1 stop
$281Delta
Tue, Jun 16 - Tue, Jun 16
American Airlines Logo
5:00 am - 12:52 pm
MEM
-
DSM
7h 52m
1 stop
American Airlines Logo
8:05 pm - 12:22 am
DSM
-
MEM
4h 17m
1 stop
$347American Airlines
Thu, Jun 25 - Thu, Jun 25
United Airlines Logo
2:37 pm - 9:28 pm
MEM
-
DSM
6h 51m
1 stop
United Airlines Logo
3:22 pm - 10:58 pm
DSM
-
MEM
7h 36m
1 stop
$351United Airlines
Tue, Sep 22 - Wed, Sep 23
Southwest Logo
5:30 am - 1:10 pm
MEM
-
DSM
7h 40m
2 stops
Southwest Logo
5:25 am - 11:45 am
DSM
-
MEM
6h 20m
1 stop
$352Southwest
Fri, Nov 13 - Sun, Nov 15
United Airlines Logo
6:45 am - 4:19 pm
MEM
-
DSM
9h 34m
2 stops
United Airlines Logo
1:35 pm - 8:42 pm
DSM
-
MEM
7h 07m
1 stop
$356United Airlines
Tue, Sep 22 - Wed, Sep 23
Southwest Logo
12:15 pm - 10:20 pm
MEM
-
DSM
10h 05m
2 stops
Southwest Logo
4:15 pm - 11:40 pm
DSM
-
MEM
7h 25m
1 stop
$358Southwest
Fri, Jul 3 - Sun, Jul 5
United Airlines Logo
9:00 am - 9:28 pm
MEM
-
DSM
12h 28m
2 stops
United Airlines Logo
11:32 am - 11:29 pm
DSM
-
MEM
11h 57m
2 stops
$361United Airlines
Tue, Sep 22 - Wed, Sep 23
Delta Logo
10:15 am - 3:15 pm
MEM
-
DSM
5h 00m
1 stop
Delta Logo
10:54 am - 5:59 pm
DSM
-
MEM
7h 05m
1 stop
$364Delta
Sat, Jun 6 - Tue, Jun 16
American Airlines Logo
5:48 pm - 12:35 am
MEM
-
DSM
6h 47m
1 stop
American Airlines Logo
7:02 pm - 11:59 pm
DSM
-
MEM
4h 57m
1 stop
$367American Airlines
Fri, Jun 19 - Sun, Jun 21
Southwest Logo
9:45 am - 2:50 pm
MEM
-
DSM
5h 05m
1 stop
Southwest Logo
5:20 am - 3:00 pm
DSM
-
MEM
9h 40m
2 stops
$369Southwest
Sat, Jun 6 - Tue, Jun 16

United Airlines flights from Memphis to Des Moines

Our best United Airlines deals on Memphis to Des Moines flight tickets
United Airlines
Sep 22
MEM2:37 pmMemphis
6h 51m
1 stop
DSM9:28 pmDes Moines
Sep 23
DSM3:22 pmDes Moines
7h 36m
1 stop
MEM10:58 pmMemphis
$351
United Airlines
Sep 22
MEM6:45 amMemphis
9h 34m
2 stops
DSM4:19 pmDes Moines
Sep 23
DSM1:35 pmDes Moines
7h 07m
1 stop
MEM8:42 pmMemphis
$356
United Airlines
Sep 22
MEM9:00 amMemphis
12h 28m
2 stops
DSM9:28 pmDes Moines
Sep 23
DSM11:32 amDes Moines
11h 57m
2 stops
MEM11:29 pmMemphis
$361

American Airlines flights from Memphis to Des Moines

Our best American Airlines deals on Memphis to Des Moines flight tickets
American Airlines
Jun 25
MEM5:00 amMemphis
7h 52m
1 stop
DSM12:52 pmDes Moines
Jun 25
DSM8:05 pmDes Moines
4h 17m
1 stop
MEM12:22 amMemphis
$347
American Airlines
Jun 19
MEM5:48 pmMemphis
6h 47m
1 stop
DSM12:35 amDes Moines
Jun 21
DSM7:02 pmDes Moines
4h 57m
1 stop
MEM11:59 pmMemphis
$367
American Airlines
Jun 9
MEM9:24 amMemphis
6h 39m
1 stop
DSM4:03 pmDes Moines
Jun 19
DSM5:00 amDes Moines
5h 02m
1 stop
MEM10:02 amMemphis
$417

momondo Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 6/16

6:00 am-10:14 am

1 stop4h 14m

Des Moines

Tue 6/16

6:03 pm-10:21 pm

1 stop4h 18m

$281

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Thu 6/25

5:00 am-12:52 pm

1 stop7h 52m

Des Moines

Thu 6/25

8:05 pm-12:22 am

1 stop4h 17m

$347

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 9/22

2:37 pm-9:28 pm

1 stop6h 51m

Des Moines

Wed 9/23

3:22 pm-10:58 pm

1 stop7h 36m

$351

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 11/13

5:30 am-1:10 pm

2 stops7h 40m

Des Moines

Sun 11/15

5:25 am-11:45 am

1 stop6h 20m

$352

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 9/22

6:45 am-4:19 pm

2 stops9h 34m

Des Moines

Wed 9/23

1:35 pm-8:42 pm

1 stop7h 07m

$356

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 7/3

12:15 pm-10:20 pm

2 stops10h 05m

Des Moines

Sun 7/5

4:15 pm-11:40 pm

1 stop7h 25m

$358

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 9/22

9:00 am-9:28 pm

2 stops12h 28m

Des Moines

Wed 9/23

11:32 am-11:29 pm

2 stops11h 57m

$361

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 6/6

10:15 am-3:15 pm

1 stop5h 00m

Des Moines

Tue 6/16

10:54 am-5:59 pm

1 stop7h 05m

$364

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 6/19

5:48 pm-12:35 am

1 stop6h 47m

Des Moines

Sun 6/21

7:02 pm-11:59 pm

1 stop4h 57m

$367

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 6/6

9:45 am-2:50 pm

1 stop5h 05m

Des Moines

Tue 6/16

5:20 am-3:00 pm

2 stops9h 40m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Memphis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Memphis and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then November is your next best option. Flight prices from Memphis to Des Moines during November average around $0.

How have Memphis to Des Moines flight prices changed over time?

When to book flights from Memphis to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Memphis to Des Moines (MEM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Des Moines

Fastest flight time

4h 14m

Direct flights

None
The fastest flight from Memphis to Des Moines takes 4h 14m
There are no direct flights from Memphis to Des Moines. There are no popular flight routes from Memphis to Des Moines.
Search flight deals

Frequently asked questions about flying from Memphis to Des Moines

  • How far is Memphis to Des Moines by plane?

    Des Moines is 484.7 mi away from Memphis. In terms of flight time, this usually takes a little over 4h 14m.

  • When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?

    Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?

  • How old do you have to be to fly from Memphis Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Memphis to Des Moines?

Best airlines flying from Memphis to Des Moines

Compare and see reviews for airlines that fly from Memphis to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $185Free CancellationRating
7.1
11,629 reviews
Search American Airlines flights
DeltaPriceFrom $201Free CancellationRating
7.9
8,425 reviews
Search Delta flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Boone
Osceola
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Des Moines?

It is quick and easy to find Memphis to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Memphis to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Memphis to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Memphis to Des Moines?

Once all potential Memphis to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Memphis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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