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Cheap flights from Memphis to Des Moines from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Memphis to Des Moines departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Memphis to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:45 pm - 9:27 pm
MEM
-
DSM
6h 42m
1 stop
United Airlines Logo
1:32 pm - 8:49 pm
DSM
-
MEM
7h 17m
1 stop
$257United Airlines
Tue, Apr 7 - Thu, Apr 9
American Airlines Logo
7:34 pm - 11:49 pm
MEM
-
DSM
4h 15m
1 stop
American Airlines Logo
11:09 am - 11:59 pm
DSM
-
MEM
12h 50m
1 stop
$260American Airlines
Mon, Apr 13 - Wed, Apr 15
American Airlines Logo
7:34 pm - 11:49 pm
MEM
-
DSM
4h 15m
1 stop
American Airlines Logo
11:09 am - 7:47 pm
DSM
-
MEM
8h 38m
2 stops
$269American Airlines
Mon, Apr 13 - Wed, Apr 15
United Airlines Logo
6:37 pm - 11:02 pm
MEM
-
DSM
4h 25m
1 stop
United Airlines Logo
6:20 am - 10:54 am
DSM
-
MEM
4h 34m
1 stop
$274United Airlines
Mon, Apr 6 - Thu, Apr 9
American Airlines Logo
7:34 pm - 10:26 am
MEM
-
DSM
14h 52m
1 stop
American Airlines Logo
12:00 pm - 7:04 pm
DSM
-
MEM
7h 04m
1 stop
$285American Airlines
Wed, Apr 8 - Fri, Apr 10
Southwest Logo
12:20 pm - 9:15 pm
MEM
-
DSM
8h 55m
2 stops
Southwest Logo
4:20 pm - 11:25 pm
DSM
-
MEM
7h 05m
1 stop
$288Southwest
Tue, Apr 7 - Thu, Apr 9
American Airlines Logo
6:36 am - 7:33 pm
MEM
-
DSM
12h 57m
1 stop
American Airlines Logo
11:09 am - 7:47 pm
DSM
-
MEM
8h 38m
2 stops
$290American Airlines
Wed, Apr 8 - Fri, Apr 10
United Airlines Logo
9:50 am - 2:25 pm
MEM
-
DSM
4h 35m
1 stop
United Airlines Logo
6:20 am - 10:54 am
DSM
-
MEM
4h 34m
1 stop
$299United Airlines
Sun, Apr 5 - Thu, Apr 9
United Airlines Logo
8:40 am - 4:15 pm
MEM
-
DSM
7h 35m
1 stop
United Airlines Logo
8:00 am - 2:39 pm
DSM
-
MEM
6h 39m
1 stop
$302United Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
6:12 pm - 11:59 pm
MEM
-
DSM
5h 47m
1 stop
American Airlines Logo
11:09 am - 7:47 pm
DSM
-
MEM
8h 38m
2 stops
$304American Airlines
Sat, Apr 11 - Fri, Apr 17

American Airlines flights from Memphis to Des Moines

Our best American Airlines deals on Memphis to Des Moines flight tickets
American Airlines
Apr 13
MEM7:34 pmMemphis
4h 15m
1 stop
DSM11:49 pmDes Moines
Apr 15
DSM11:09 amDes Moines
12h 50m
1 stop
MEM11:59 pmMemphis
$260
American Airlines
Apr 13
MEM7:34 pmMemphis
4h 15m
1 stop
DSM11:49 pmDes Moines
Apr 15
DSM11:09 amDes Moines
8h 38m
2 stops
MEM7:47 pmMemphis
$269
American Airlines
Apr 8
MEM7:34 pmMemphis
14h 52m
1 stop
DSM10:26 amDes Moines
Apr 10
DSM12:00 pmDes Moines
7h 04m
1 stop
MEM7:04 pmMemphis
$285

Southwest flights from Memphis to Des Moines

Our best Southwest deals on Memphis to Des Moines flight tickets
Southwest
Apr 7
MEM12:20 pmMemphis
8h 55m
2 stops
DSM9:15 pmDes Moines
Apr 9
DSM4:20 pmDes Moines
7h 05m
1 stop
MEM11:25 pmMemphis
$288
Southwest
Apr 13
MEM12:30 pmMemphis
10h 35m
2 stops
DSM11:05 pmDes Moines
Apr 15
DSM6:55 amDes Moines
10h 40m
2 stops
MEM5:35 pmMemphis
$305
Southwest
May 8
MEM12:20 pmMemphis
10h 45m
2 stops
DSM11:05 pmDes Moines
May 11
DSM4:20 pmDes Moines
7h 05m
1 stop
MEM11:25 pmMemphis
$317

momondo Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 4/7

2:45 pm-9:27 pm

1 stop6h 42m

Des Moines

Thu 4/9

1:32 pm-8:49 pm

1 stop7h 17m

$257

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 4/13

7:34 pm-11:49 pm

1 stop4h 15m

Des Moines

Wed 4/15

11:09 am-11:59 pm

1 stop12h 50m

$260

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 4/13

7:34 pm-11:49 pm

1 stop4h 15m

Des Moines

Wed 4/15

11:09 am-7:47 pm

2 stops8h 38m

$269

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 4/6

6:37 pm-11:02 pm

1 stop4h 25m

Des Moines

Thu 4/9

6:20 am-10:54 am

1 stop4h 34m

$274

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 4/8

7:34 pm-10:26 am

1 stop14h 52m

Des Moines

Fri 4/10

12:00 pm-7:04 pm

1 stop7h 04m

$285

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 4/7

12:20 pm-9:15 pm

2 stops8h 55m

Des Moines

Thu 4/9

4:20 pm-11:25 pm

1 stop7h 05m

$288

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 4/8

6:36 am-7:33 pm

1 stop12h 57m

Des Moines

Fri 4/10

11:09 am-7:47 pm

2 stops8h 38m

$290

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 4/5

9:50 am-2:25 pm

1 stop4h 35m

Des Moines

Thu 4/9

6:20 am-10:54 am

1 stop4h 34m

$299

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Thu 5/7

8:40 am-4:15 pm

1 stop7h 35m

Des Moines

Sun 5/10

8:00 am-2:39 pm

1 stop6h 39m

$302

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 4/11

6:12 pm-11:59 pm

1 stop5h 47m

Des Moines

Fri 4/17

11:09 am-7:47 pm

2 stops8h 38m

$304

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Memphis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

How have Memphis to Des Moines flight prices changed over time?

When to book flights from Memphis to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Memphis to Des Moines (MEM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Des Moines

Fastest flight time

6h 42m

Direct flights

None
The fastest flight from Memphis to Des Moines takes 6h 42m
There are no direct flights from Memphis to Des Moines. There are no popular flight routes from Memphis to Des Moines.
Search flight deals

  • How far is Memphis to Des Moines by plane?

    Des Moines is 484.7 mi away from Memphis. In terms of flight time, this usually takes a little over 6h 42m.

  • When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?

    Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?

  • How old do you have to be to fly from Memphis Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Memphis to Des Moines?

Best airlines flying from Memphis to Des Moines

Compare and see reviews for airlines that fly from Memphis to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $201Free CancellationRating
7.9
8,239 reviews
Search Delta flights
American AirlinesPriceFrom $241Free CancellationRating
7.2
11,344 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Des Moines?

It is quick and easy to find Memphis to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Memphis to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Memphis to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Memphis to Des Moines?

Once all potential Memphis to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Memphis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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