What is the cheapest airline that flies from Memphis to Des Moines?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Memphis to Des Moines

When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?

Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?

As of December 2025, there is 1 operator available to choose from for flights from Memphis Airport to Des Moines Airport.

How old do you have to be to fly from Memphis Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$126 Cheap Flights from Memphis to Des Moines in 2025/26

1 adult

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Find the cheapest flights from Memphis to Des Moines

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:30 am - 2:27 pm

MEM

DSM

6h 57m1 stop

3:24 pm - 9:59 pm

DSM

MEM

6h 35m1 stop

$289United Airlines

Sat, Feb 14 - Wed, Feb 18

8:37 am - 4:24 pm

MEM

DSM

7h 47m2 stops

4:00 pm - 10:51 pm

DSM

MEM

6h 51m1 stop

$295American Airlines

Sun, Feb 1 - Sat, Feb 7

10:27 am - 8:02 pm

MEM

DSM

9h 35m2 stops

6:00 am - 3:18 pm

DSM

MEM

9h 18m2 stops

$300American Airlines

Sun, Feb 1 - Sat, Feb 7

6:22 pm - 10:52 pm

MEM

DSM

4h 30m1 stop

3:00 pm - 8:06 pm

DSM

MEM

5h 06m1 stop

$317United Airlines

Sun, Jun 14 - Wed, Jun 17

5:10 am - 11:25 am

MEM

DSM

6h 15m1 stop

5:20 am - 3:00 pm

DSM

MEM

9h 40m2 stops

$362Southwest

Sun, Jun 14 - Wed, Jun 17

5:10 am - 3:35 pm

MEM

DSM

10h 25m2 stops

5:20 am - 3:00 pm

DSM

MEM

9h 40m2 stops

$377Southwest

Sun, Jun 14 - Wed, Jun 17

7:30 am - 2:11 pm

MEM

DSM

6h 41m1 stop

6:15 am - 10:32 am

DSM

MEM

4h 17m1 stop

$382United Airlines

Mon, Jun 15 - Thu, Jun 18

7:30 am - 2:27 pm

MEM

DSM

6h 57m1 stop

8:00 am - 6:14 pm

DSM

MEM

10h 14m2 stops

$423United Airlines

Sat, Feb 14 - Wed, Feb 18

2:30 pm - 11:20 pm

MEM

DSM

8h 50m2 stops

5:10 am - 11:40 am

DSM

MEM

6h 30m1 stop

$452Southwest

Mon, Jun 15 - Thu, Jun 18

2:30 pm - 11:20 pm

MEM

DSM

8h 50m2 stops

4:40 pm - 11:55 pm

DSM

MEM

7h 15m2 stops

$502Southwest

Mon, Jun 15 - Thu, Jun 18

Southwest flights from Memphis to Des Moines

Our best Southwest deals on Memphis to Des Moines flight tickets

Southwest

Jun 14

MEM5:10 amMemphis

6h 15m

1 stop

DSM11:25 amDes Moines

Jun 17

DSM5:20 amDes Moines

9h 40m

2 stops

MEM3:00 pmMemphis

$362

Find similar

Southwest

Jun 14

MEM5:10 amMemphis

10h 25m

2 stops

DSM3:35 pmDes Moines

Jun 17

DSM5:20 amDes Moines

9h 40m

2 stops

MEM3:00 pmMemphis

$377

Find similar

Southwest

Jun 15

MEM2:30 pmMemphis

8h 50m

2 stops

DSM11:20 pmDes Moines

Jun 18

DSM5:10 amDes Moines

6h 30m

1 stop

MEM11:40 amMemphis

$452

Find similar

United Airlines flights from Memphis to Des Moines

Our best United Airlines deals on Memphis to Des Moines flight tickets

United Airlines

Feb 14

MEM7:30 amMemphis

6h 57m

1 stop

DSM2:27 pmDes Moines

Feb 18

DSM3:24 pmDes Moines

6h 35m

1 stop

MEM9:59 pmMemphis

$289

Find similar

United Airlines

Jun 14

MEM6:22 pmMemphis

4h 30m

1 stop

DSM10:52 pmDes Moines

Jun 17

DSM3:00 pmDes Moines

5h 06m

1 stop

MEM8:06 pmMemphis

$317

Find similar

United Airlines

Jun 15

MEM7:30 amMemphis

6h 41m

1 stop

DSM2:11 pmDes Moines

Jun 18

DSM6:15 amDes Moines

4h 17m

1 stop

MEM10:32 amMemphis

$382

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 2/14

7:30 am-2:27 pm

1 stop6h 57m

Des Moines

Wed 2/18

3:24 pm-9:59 pm

1 stop6h 35m

$289

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 2/1

8:37 am-4:24 pm

2 stops7h 47m

Des Moines

Sat 2/7

4:00 pm-10:51 pm

1 stop6h 51m

$295

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 2/1

10:27 am-8:02 pm

2 stops9h 35m

Des Moines

Sat 2/7

6:00 am-3:18 pm

2 stops9h 18m

$300

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 6/14

6:22 pm-10:52 pm

1 stop4h 30m

Des Moines

Wed 6/17

3:00 pm-8:06 pm

1 stop5h 06m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 6/14

5:10 am-11:25 am

1 stop6h 15m

Des Moines

Wed 6/17

5:20 am-3:00 pm

2 stops9h 40m

$362

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 6/14

5:10 am-3:35 pm

2 stops10h 25m

Des Moines

Wed 6/17

5:20 am-3:00 pm

2 stops9h 40m

$377

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 6/15

7:30 am-2:11 pm

1 stop6h 41m

Des Moines

Thu 6/18

6:15 am-10:32 am

1 stop4h 17m

$382

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 2/14

7:30 am-2:27 pm

1 stop6h 57m

Des Moines

Wed 2/18

8:00 am-6:14 pm

2 stops10h 14m

$423

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 6/15

2:30 pm-11:20 pm

2 stops8h 50m

Des Moines

Thu 6/18

5:10 am-11:40 am

1 stop6h 30m

$452

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 6/15

2:30 pm-11:20 pm

2 stops8h 50m

Des Moines

Thu 6/18

4:40 pm-11:55 pm

2 stops7h 15m

$502

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Memphis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Memphis to Des Moines is on a Monday. Travelers who choose to depart for Des Moines on a Monday will often find tickets for as low as $266. Flights from Memphis to Des Moines on a Friday will generally be more expensive and average around $363. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Memphis to Des Moines in the morning for as low as $321. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $490. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Memphis to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Memphis to Des Moines (MEM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Des Moines

Fastest flight time	4h 30m
Direct flights	None

The fastest flight from Memphis to Des Moines takes 4h 30m

There are no direct flights from Memphis to Des Moines. There are no popular flight routes from Memphis to Des Moines.

Search flight deals

How far is Memphis to Des Moines by plane?
Des Moines is 484.7 mi away from Memphis. In terms of flight time, this usually takes a little over 4h 30m.
When did momondo last update prices for flights from Memphis Airport to Des Moines Airport?
Prices for flights from Memphis Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Memphis Airport to Des Moines Airport?
As of December 2025, there is 1 operator available to choose from for flights from Memphis Airport to Des Moines Airport.
How old do you have to be to fly from Memphis Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Memphis Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Memphis to Des Moines?
Based on momondo bookings for flights between Memphis and Des Moines, the leading airline is American Airlines, making up 100% of the total bookings.

Best airlines flying from Memphis to Des Moines

Compare and see reviews for airlines that fly from Memphis to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $241	Free Cancellation	Rating 7.2 11,067 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Des Moines?

It is quick and easy to find Memphis to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Memphis to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Memphis to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Memphis to Des Moines?

Once all potential Memphis to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Memphis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.