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Cheap flights from Madrid to Des Moines from $544

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Des Moines departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Madrid to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:05 am - 4:48 pm
MAD
-
DSM
16h 43m
2 stops
Multiple Airlines Logo
5:28 pm - 3:35 pm
DSM
-
MAD
15h 07m
2 stops
$973Multiple Airlines
Wed, May 27 - Tue, Jun 2
KLM Logo
7:05 am - 4:48 pm
MAD
-
DSM
16h 43m
2 stops
KLM Logo
6:41 pm - 12:15 pm
DSM
-
MAD
34h 34m
1 stop
$977KLM
Wed, May 27 - Tue, Jun 2
KLM Logo
9:50 am - 10:32 pm
MAD
-
DSM
19h 42m
1 stop
KLM Logo
6:41 pm - 12:15 pm
DSM
-
MAD
34h 34m
1 stop
$982KLM
Wed, May 27 - Tue, Jun 2
United Airlines Logo
11:15 am - 11:01 pm
MAD
-
DSM
18h 46m
2 stops
United Airlines Logo
6:15 am - 8:05 am
DSM
-
MAD
18h 50m
2 stops
$1,007United Airlines
Wed, Oct 14 - Sun, Oct 18
United Airlines Logo
11:15 am - 12:40 am
MAD
-
DSM
20h 25m
2 stops
United Airlines Logo
8:00 am - 8:05 am
DSM
-
MAD
17h 05m
2 stops
$1,009United Airlines
Wed, Oct 14 - Sun, Oct 18
United Airlines Logo
11:15 am - 12:40 am
MAD
-
DSM
20h 25m
2 stops
United Airlines Logo
8:00 am - 8:05 am
DSM
-
MAD
17h 05m
2 stops
$1,010United Airlines
Wed, Oct 14 - Sun, Oct 18
KLM Logo
7:05 am - 5:06 pm
MAD
-
DSM
17h 01m
2 stops
KLM Logo
6:39 pm - 12:15 pm
DSM
-
MAD
34h 36m
1 stop
$1,055KLM
Wed, Jun 3 - Wed, Jun 10
KLM Logo
7:05 am - 5:06 pm
MAD
-
DSM
17h 01m
2 stops
KLM Logo
6:39 pm - 12:15 pm
DSM
-
MAD
34h 36m
1 stop
$1,056KLM
Wed, Jun 3 - Wed, Jun 10
KLM Logo
7:05 am - 5:06 pm
MAD
-
DSM
17h 01m
2 stops
KLM Logo
6:39 pm - 12:15 pm
DSM
-
MAD
34h 36m
1 stop
$1,058KLM
Wed, Jun 3 - Wed, Jun 10
KLM Logo
7:05 am - 4:48 pm
MAD
-
DSM
16h 43m
2 stops
KLM Logo
6:39 pm - 12:15 pm
DSM
-
MAD
34h 36m
1 stop
$1,059KLM
Wed, Jun 3 - Wed, Jun 10

Delta flights from Madrid to Des Moines

Our best Delta deals on Madrid to Des Moines flight tickets
Delta
May 16
MAD9:50 amMadrid Barajas
17h 32m
1 stop
DSM8:22 pmDes Moines
May 20
DSM10:56 amDes Moines
15h 34m
2 stops
MAD9:30 amMadrid Barajas
$1,137
Delta
Jun 18
MAD9:50 amMadrid Barajas
15h 04m
1 stop
DSM5:54 pmDes Moines
Jun 25
DSM6:03 pmDes Moines
18h 12m
2 stops
MAD7:15 pmMadrid Barajas
$1,157
Delta
Jun 29
MAD6:00 amMadrid Barajas
17h 54m
2 stops
DSM4:54 pmDes Moines
Aug 3
DSM5:56 pmDes Moines
14h 39m
2 stops
MAD3:35 pmMadrid Barajas
$1,175

KLM flights from Madrid to Des Moines

Our best KLM deals on Madrid to Des Moines flight tickets
KLM
May 27
MAD7:05 amMadrid Barajas
16h 43m
2 stops
DSM4:48 pmDes Moines
Jun 2
DSM6:41 pmDes Moines
34h 34m
1 stop
MAD12:15 pmMadrid Barajas
$977
KLM
May 27
MAD9:50 amMadrid Barajas
19h 42m
1 stop
DSM10:32 pmDes Moines
Jun 2
DSM6:41 pmDes Moines
34h 34m
1 stop
MAD12:15 pmMadrid Barajas
$982
KLM
Jun 3
MAD7:05 amMadrid Barajas
17h 01m
2 stops
DSM5:06 pmDes Moines
Jun 10
DSM6:39 pmDes Moines
34h 36m
1 stop
MAD12:15 pmMadrid Barajas
$1,055

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 5/27

7:05 am-4:48 pm

2 stops16h 43m

Des Moines

Tue 6/2

5:28 pm-3:35 pm

2 stops15h 07m

$973

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 5/27

7:05 am-4:48 pm

2 stops16h 43m

Des Moines

Tue 6/2

6:41 pm-12:15 pm

1 stop34h 34m

$977

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 5/27

9:50 am-10:32 pm

1 stop19h 42m

Des Moines

Tue 6/2

6:41 pm-12:15 pm

1 stop34h 34m

$982

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 10/14

11:15 am-11:01 pm

2 stops18h 46m

Des Moines

Sun 10/18

6:15 am-8:05 am

2 stops18h 50m

$1,007

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 10/14

11:15 am-12:40 am

2 stops20h 25m

Des Moines

Sun 10/18

8:00 am-8:05 am

2 stops17h 05m

$1,009

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 10/14

11:15 am-12:40 am

2 stops20h 25m

Des Moines

Sun 10/18

8:00 am-8:05 am

2 stops17h 05m

$1,010

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

7:05 am-5:06 pm

2 stops17h 01m

Des Moines

Wed 6/10

6:39 pm-12:15 pm

1 stop34h 36m

$1,055

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

7:05 am-5:06 pm

2 stops17h 01m

Des Moines

Wed 6/10

6:39 pm-12:15 pm

1 stop34h 36m

$1,056

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

7:05 am-5:06 pm

2 stops17h 01m

Des Moines

Wed 6/10

6:39 pm-12:15 pm

1 stop34h 36m

$1,058

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

7:05 am-4:48 pm

2 stops16h 43m

Des Moines

Wed 6/10

6:39 pm-12:15 pm

1 stop34h 36m

$1,059

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Madrid to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Madrid and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in March, then September is your next best option. Flight prices from Madrid to Des Moines during September average around $619.

Can stopping save me money on Madrid to Des Moines flights?

You could potentially save up to 41% on your flight if you consider stops on a Madrid to Des Moines flight.

When to book flights from Madrid to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Des Moines (MAD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Des Moines

Fastest flight time

16h 43m

Direct flights

None
The fastest flight from Madrid to Des Moines takes 16h 43m
There are no direct flights from Madrid to Des Moines. There are no popular flight routes from Madrid to Des Moines.
Search flight deals

Frequently asked questions about flying from Madrid to Des Moines

  • How far is Madrid Barajas to Des Moines by plane?

    The straight-line distance from Madrid Barajas to Des Moines is 4451.0 mi. Typically, this will take 16h 43m by plane in normal conditions.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Des Moines Airport?

    Prices for flights from Madrid Barajas Airport to Des Moines Airport were last updated today.

  • How old do you have to be to fly from Madrid Barajas Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Des Moines?

Finding the right flight to Des Moines from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Madrid to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Madrid with this policy.

How can momondo help me find flights from Madrid to Des Moines?

Once you have performed a search for Madrid to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Madrid to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Madrid to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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