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Cheap flights from Madrid to Des Moines from $420

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Des Moines departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Madrid to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:35 pm - 1:50 pm
MAD
-
DSM
29h 15m
1 stop
Multiple Airlines Logo
7:35 am - 8:40 am
DSM
-
MAD
42h 05m
2 stops
$873Multiple Airlines
Thu, Jun 4 - Mon, Jul 20
Delta Logo
6:00 am - 5:02 pm
MAD
-
DSM
18h 02m
2 stops
Delta Logo
10:56 am - 11:20 am
DSM
-
MAD
17h 24m
2 stops
$914Delta
Sat, May 2 - Sat, May 9
KLM Logo
6:00 am - 5:02 pm
MAD
-
DSM
18h 02m
2 stops
KLM Logo
4:00 pm - 12:15 pm
DSM
-
MAD
13h 15m
1 stop
$917KLM
Sat, May 2 - Sat, May 9
Virgin Atlantic Logo
12:45 pm - 10:34 pm
MAD
-
DSM
16h 49m
1 stop
Virgin Atlantic Logo
11:57 am - 12:15 pm
DSM
-
MAD
17h 18m
1 stop
$923Virgin Atlantic
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
3:35 pm - 1:50 pm
MAD
-
DSM
29h 15m
1 stop
Multiple Airlines Logo
7:35 am - 8:40 am
DSM
-
MAD
42h 05m
2 stops
$927Multiple Airlines
Thu, Jun 4 - Mon, Jul 20
Multiple Airlines Logo
4:30 pm - 3:35 pm
MAD
-
DSM
30h 05m
1 stop
Multiple Airlines Logo
7:35 am - 7:50 pm
DSM
-
MAD
29h 15m
2 stops
$930Multiple Airlines
Mon, Jun 1 - Mon, Jul 20
Multiple Airlines Logo
6:00 am - 4:54 pm
MAD
-
DSM
17h 54m
2 stops
Multiple Airlines Logo
5:47 pm - 4:45 pm
DSM
-
MAD
15h 58m
2 stops
$936Multiple Airlines
Sat, Apr 4 - Wed, Apr 8
Multiple Airlines Logo
6:00 am - 4:54 pm
MAD
-
DSM
17h 54m
2 stops
Multiple Airlines Logo
5:47 pm - 3:35 pm
DSM
-
MAD
14h 48m
2 stops
$937Multiple Airlines
Sat, Apr 4 - Wed, Apr 8
Multiple Airlines Logo
6:00 am - 4:54 pm
MAD
-
DSM
17h 54m
2 stops
Multiple Airlines Logo
5:47 pm - 4:45 pm
DSM
-
MAD
15h 58m
2 stops
$940Multiple Airlines
Sat, Apr 4 - Wed, Apr 8
Delta Logo
10:25 am - 8:36 pm
MAD
-
DSM
17h 11m
2 stops
Delta Logo
2:48 pm - 3:35 pm
DSM
-
MAD
17h 47m
2 stops
$941Delta
Thu, Jun 4 - Wed, Jul 15

Delta flights from Madrid to Des Moines

Our best Delta deals on Madrid to Des Moines flight tickets
Delta
May 2
MAD6:00 amMadrid Barajas
18h 02m
2 stops
DSM5:02 pmDes Moines
May 9
DSM10:56 amDes Moines
17h 24m
2 stops
MAD11:20 amMadrid Barajas
$914
Delta
Jun 4
MAD10:25 amMadrid Barajas
17h 11m
2 stops
DSM8:36 pmDes Moines
Jul 15
DSM2:48 pmDes Moines
17h 47m
2 stops
MAD3:35 pmMadrid Barajas
$941
Delta
May 5
MAD6:00 amMadrid Barajas
21h 39m
2 stops
DSM8:39 pmDes Moines
May 12
DSM6:15 amDes Moines
20h 40m
2 stops
MAD9:55 amMadrid Barajas
$944

KLM flights from Madrid to Des Moines

Our best KLM deals on Madrid to Des Moines flight tickets
KLM
May 2
MAD6:00 amMadrid Barajas
18h 02m
2 stops
DSM5:02 pmDes Moines
May 9
DSM4:00 pmDes Moines
13h 15m
1 stop
MAD12:15 pmMadrid Barajas
$917
KLM
May 5
MAD12:45 pmMadrid Barajas
16h 49m
1 stop
DSM10:34 pmDes Moines
May 12
DSM6:41 pmDes Moines
34h 34m
1 stop
MAD12:15 pmMadrid Barajas
$987
KLM
Apr 4
MAD6:00 amMadrid Barajas
16h 42m
2 stops
DSM3:42 pmDes Moines
Apr 8
DSM5:35 amDes Moines
23h 40m
1 stop
MAD12:15 pmMadrid Barajas
$1,150

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 6/4

3:35 pm-1:50 pm

1 stop29h 15m

Des Moines

Mon 7/20

7:35 am-8:40 am

2 stops42h 05m

$873

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 5/2

6:00 am-5:02 pm

2 stops18h 02m

Des Moines

Sat 5/9

10:56 am-11:20 am

2 stops17h 24m

$914
Quickest round-trip

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 5/2

6:00 am-5:02 pm

2 stops18h 02m

Des Moines

Sat 5/9

4:00 pm-12:15 pm

1 stop13h 15m

$917

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 5/2

12:45 pm-10:34 pm

1 stop16h 49m

Des Moines

Sat 5/9

11:57 am-12:15 pm

1 stop17h 18m

$923

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 6/4

3:35 pm-1:50 pm

1 stop29h 15m

Des Moines

Mon 7/20

7:35 am-8:40 am

2 stops42h 05m

$927

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 6/1

4:30 pm-3:35 pm

1 stop30h 05m

Des Moines

Mon 7/20

7:35 am-7:50 pm

2 stops29h 15m

$930

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 4/4

6:00 am-4:54 pm

2 stops17h 54m

Des Moines

Wed 4/8

5:47 pm-4:45 pm

2 stops15h 58m

$936

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 4/4

6:00 am-4:54 pm

2 stops17h 54m

Des Moines

Wed 4/8

5:47 pm-3:35 pm

2 stops14h 48m

$937

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 4/4

6:00 am-4:54 pm

2 stops17h 54m

Des Moines

Wed 4/8

5:47 pm-4:45 pm

2 stops15h 58m

$940

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 6/4

10:25 am-8:36 pm

2 stops17h 11m

Des Moines

Wed 7/15

2:48 pm-3:35 pm

2 stops17h 47m

$941

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Madrid to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then May is your next best option. Flight prices from Madrid to Des Moines during May average around $893.

Can stopping save me money on Madrid to Des Moines flights?

You could potentially save up to 49% on your flight if you consider stops on a Madrid to Des Moines flight.

When to book flights from Madrid to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Des Moines (MAD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Des Moines

Fastest flight time

17h 48m

Direct flights

None
The fastest flight from Madrid to Des Moines takes 17h 48m
There are no direct flights from Madrid to Des Moines. There are no popular flight routes from Madrid to Des Moines.
Search flight deals

  • How far is Madrid Barajas to Des Moines by plane?

    The straight-line distance from Madrid Barajas to Des Moines is 4451.0 mi. Typically, this will take 17h 48m by plane in normal conditions.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Des Moines Airport?

    Prices for flights from Madrid Barajas Airport to Des Moines Airport were last updated today.

  • How old do you have to be to fly from Madrid Barajas Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Des Moines?

Finding the right flight to Des Moines from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Madrid to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Madrid with this policy.

How can momondo help me find flights from Madrid to Des Moines?

Once you have performed a search for Madrid to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Madrid to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Madrid to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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