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Cheap flights from Lyon to South Carolina from $543

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Lyon to South Carolina departing on 2/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Lyon to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:10 am - 4:20 pm
LYS
-
CLT
16h 10m
1 stop
American Airlines Logo
1:06 pm - 3:10 pm
CLT
-
LYS
20h 04m
2 stops
$595American Airlines
Fri, Feb 27 - Tue, Mar 3
United Airlines Logo
6:25 am - 6:55 pm
LYS
-
CLT
18h 30m
2 stops
United Airlines Logo
7:44 pm - 11:05 am
CLT
-
LYS
33h 21m
2 stops
$596United Airlines
Fri, Feb 27 - Tue, Mar 3
American Airlines Logo
6:10 am - 7:56 pm
LYS
-
CLT
19h 46m
2 stops
American Airlines Logo
8:20 pm - 3:10 pm
CLT
-
LYS
12h 50m
1 stop
$604American Airlines
Fri, Feb 27 - Tue, Mar 3
American Airlines Logo
12:25 pm - 10:05 am
LYS
-
CLT
27h 40m
2 stops
American Airlines Logo
8:20 pm - 3:10 pm
CLT
-
LYS
12h 50m
1 stop
$605American Airlines
Fri, Feb 27 - Tue, Mar 3
American Airlines Logo
6:10 am - 4:20 pm
LYS
-
CLT
16h 10m
1 stop
American Airlines Logo
6:25 pm - 12:20 pm
CLT
-
LYS
11h 55m
1 stop
$642American Airlines
Fri, Feb 27 - Tue, Mar 3
British Airways Logo
9:45 pm - 4:47 pm
LYS
-
CLT
25h 02m
2 stops
British Airways Logo
4:39 pm - 2:25 pm
CLT
-
LYS
15h 46m
2 stops
$718British Airways
Wed, Apr 15 - Sat, May 2
British Airways Logo
9:45 pm - 1:10 pm
LYS
-
CLT
21h 25m
1 stop
British Airways Logo
3:04 pm - 2:25 pm
CLT
-
LYS
17h 21m
2 stops
$755British Airways
Wed, Apr 15 - Sat, May 2
Multiple Airlines Logo
3:30 pm - 10:33 pm
LYS
-
CHS
36h 03m
3 stops
Multiple Airlines Logo
5:02 pm - 5:35 pm
CHS
-
LYS
19h 33m
2 stops
$1,351Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
Multiple Airlines Logo
3:30 pm - 10:33 pm
LYS
-
CHS
36h 03m
3 stops
Multiple Airlines Logo
5:02 pm - 6:55 pm
CHS
-
LYS
20h 53m
3 stops
$1,356Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
Air Canada Logo
12:55 pm - 11:22 am
LYS
-
GSP
27h 27m
3 stops
Air Canada Logo
10:40 am - 10:05 am
GSP
-
LYS
18h 25m
3 stops
$1,991Air Canada
Sat, Mar 14 - Sat, Mar 21

United Airlines flights from Lyon to South Carolina

Our best United Airlines deals on Lyon to South Carolina flight tickets
United Airlines
Feb 27
LYS6:25 amLyon-Saint Exupéry
18h 30m
2 stops
CLT6:55 pmCharlotte Douglas
Mar 3
CLT7:44 pmCharlotte Douglas
33h 21m
2 stops
LYS11:05 amLyon-Saint Exupéry
$596
United Airlines
Apr 15
LYS6:25 amLyon-Saint Exupéry
18h 20m
2 stops
CLT6:45 pmCharlotte Douglas
May 2
CLT6:40 pmCharlotte Douglas
11h 40m
1 stop
LYS12:20 pmLyon-Saint Exupéry
$751
United Airlines
Apr 15
LYS9:25 amLyon-Saint Exupéry
13h 20m
1 stop
CLT4:45 pmCharlotte Douglas
May 2
CLT6:40 pmCharlotte Douglas
11h 40m
1 stop
LYS12:20 pmLyon-Saint Exupéry
$758

American Airlines flights from Lyon to South Carolina

Our best American Airlines deals on Lyon to South Carolina flight tickets
American Airlines
Feb 27
LYS6:10 amLyon-Saint Exupéry
16h 10m
1 stop
CLT4:20 pmCharlotte Douglas
Mar 3
CLT1:06 pmCharlotte Douglas
20h 04m
2 stops
LYS3:10 pmLyon-Saint Exupéry
$595
American Airlines
Feb 27
LYS6:10 amLyon-Saint Exupéry
19h 46m
2 stops
CLT7:56 pmCharlotte Douglas
Mar 3
CLT8:20 pmCharlotte Douglas
12h 50m
1 stop
LYS3:10 pmLyon-Saint Exupéry
$604
American Airlines
Feb 27
LYS12:25 pmLyon-Saint Exupéry
27h 40m
2 stops
CLT10:05 amCharlotte Douglas
Mar 3
CLT8:20 pmCharlotte Douglas
12h 50m
1 stop
LYS3:10 pmLyon-Saint Exupéry
$605

momondo Fare Finder

 
Customize your flight search to find flights from Lyon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Lyon to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 2/27

6:10 am-4:20 pm

1 stop16h 10m

Charlotte Douglas

Tue 3/3

1:06 pm-3:10 pm

2 stops20h 04m

$595

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 2/27

6:25 am-6:55 pm

2 stops18h 30m

Charlotte Douglas

Tue 3/3

7:44 pm-11:05 am

2 stops33h 21m

$596

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 2/27

6:10 am-7:56 pm

2 stops19h 46m

Charlotte Douglas

Tue 3/3

8:20 pm-3:10 pm

1 stop12h 50m

$604

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 2/27

12:25 pm-10:05 am

2 stops27h 40m

Charlotte Douglas

Tue 3/3

8:20 pm-3:10 pm

1 stop12h 50m

$605

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 2/27

6:10 am-4:20 pm

1 stop16h 10m

Charlotte Douglas

Tue 3/3

6:25 pm-12:20 pm

1 stop11h 55m

$642

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Wed 4/15

9:45 pm-4:47 pm

2 stops25h 02m

Charlotte Douglas

Sat 5/2

4:39 pm-2:25 pm

2 stops15h 46m

$718

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Wed 4/15

9:45 pm-1:10 pm

1 stop21h 25m

Charlotte Douglas

Sat 5/2

3:04 pm-2:25 pm

2 stops17h 21m

$755

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Sun 3/15

3:30 pm-10:33 pm

3 stops36h 03m

Charleston

Sun 3/22

5:02 pm-5:35 pm

2 stops19h 33m

$1,351

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Sun 3/15

3:30 pm-10:33 pm

3 stops36h 03m

Charleston

Sun 3/22

5:02 pm-6:55 pm

3 stops20h 53m

$1,356

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Sat 3/14

12:55 pm-11:22 am

3 stops27h 27m

Greenville

Sat 3/21

10:40 am-10:05 am

3 stops18h 25m

$1,991

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Lyon to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Lyon-Saint Exupéry to South Carolina?

Iberia and Delta are the most popular carriers operating from Lyon-Saint Exupéry to South Carolina

Cheap Lyon to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Lyon to South Carolina

Fastest flight time

15h 27m

Direct flights

None
The fastest flight from Lyon to South Carolina takes 15h 27m
There are no direct flights from Lyon to South Carolina. There are no popular flight routes from Lyon to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Lyon-Saint Exupéry Airport to South Carolina?

    Prices for flights from Lyon-Saint Exupéry Airport to South Carolina were last updated today.

  • How old do you have to be to fly from Lyon-Saint Exupéry Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lyon-Saint Exupéry Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Lyon to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Lyon to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Lyon to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Lyon on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Lyon to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from Lyon. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Lyon to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Lyon and alert you when they change.

An easier way to manage your South Carolina trip

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