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Cheap flights from Lexington to Des Moines from $269

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Lexington to Des Moines departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Lexington to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:35 am - 2:27 pm
LEX
-
DSM
4h 52m
1 stop
United Airlines Logo
6:55 pm - 11:49 pm
DSM
-
LEX
3h 54m
1 stop
$269United Airlines
Wed, Feb 25 - Sat, Feb 28
American Airlines Logo
5:07 pm - 10:20 pm
LEX
-
DSM
6h 13m
1 stop
American Airlines Logo
5:00 am - 2:33 pm
DSM
-
LEX
8h 33m
2 stops
$274American Airlines
Fri, Mar 6 - Sat, Mar 7
American Airlines Logo
5:00 am - 1:05 pm
LEX
-
DSM
9h 05m
2 stops
American Airlines Logo
5:00 am - 9:28 am
DSM
-
LEX
3h 28m
1 stop
$305American Airlines
Sat, Feb 28 - Mon, Mar 2
American Airlines Logo
5:00 am - 1:05 pm
LEX
-
DSM
9h 05m
2 stops
American Airlines Logo
5:00 am - 9:28 am
DSM
-
LEX
3h 28m
1 stop
$309American Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
5:45 pm - 9:41 pm
LEX
-
DSM
4h 56m
1 stop
United Airlines Logo
6:55 pm - 11:49 pm
DSM
-
LEX
3h 54m
1 stop
$310United Airlines
Sat, Feb 28 - Mon, Mar 2
American Airlines Logo
5:00 am - 1:05 pm
LEX
-
DSM
9h 05m
2 stops
American Airlines Logo
5:00 am - 2:33 pm
DSM
-
LEX
8h 33m
2 stops
$314American Airlines
Wed, Feb 25 - Sat, Feb 28
American Airlines Logo
10:27 am - 11:40 pm
LEX
-
DSM
14h 13m
1 stop
American Airlines Logo
5:00 am - 9:28 am
DSM
-
LEX
3h 28m
1 stop
$332American Airlines
Thu, Feb 26 - Sat, Feb 28
American Airlines Logo
5:07 pm - 11:40 pm
LEX
-
DSM
7h 33m
1 stop
American Airlines Logo
5:00 am - 2:33 pm
DSM
-
LEX
8h 33m
2 stops
$337American Airlines
Thu, Feb 26 - Sat, Feb 28
United Airlines Logo
10:35 am - 2:27 pm
LEX
-
DSM
4h 52m
1 stop
United Airlines Logo
3:24 pm - 8:09 pm
DSM
-
LEX
3h 45m
1 stop
$383United Airlines
Thu, Feb 26 - Sat, Feb 28
American Airlines Logo
10:27 am - 11:40 pm
LEX
-
DSM
14h 13m
1 stop
American Airlines Logo
5:00 am - 2:33 pm
DSM
-
LEX
8h 33m
2 stops
$397American Airlines
Thu, Feb 26 - Sat, Feb 28

American Airlines flights from Lexington to Des Moines

Our best American Airlines deals on Lexington to Des Moines flight tickets
American Airlines
Mar 6
LEX5:07 pmLexington Blue Grass
6h 13m
1 stop
DSM10:20 pmDes Moines
Mar 7
DSM5:00 amDes Moines
8h 33m
2 stops
LEX2:33 pmLexington Blue Grass
$274
American Airlines
Feb 28
LEX5:00 amLexington Blue Grass
9h 05m
2 stops
DSM1:05 pmDes Moines
Mar 2
DSM5:00 amDes Moines
3h 28m
1 stop
LEX9:28 amLexington Blue Grass
$305
American Airlines
Feb 25
LEX5:00 amLexington Blue Grass
9h 05m
2 stops
DSM1:05 pmDes Moines
Feb 28
DSM5:00 amDes Moines
3h 28m
1 stop
LEX9:28 amLexington Blue Grass
$309

United Airlines flights from Lexington to Des Moines

Our best United Airlines deals on Lexington to Des Moines flight tickets
United Airlines
Feb 25
LEX10:35 amLexington Blue Grass
4h 52m
1 stop
DSM2:27 pmDes Moines
Feb 28
DSM6:55 pmDes Moines
3h 54m
1 stop
LEX11:49 pmLexington Blue Grass
$269
United Airlines
Feb 28
LEX5:45 pmLexington Blue Grass
4h 56m
1 stop
DSM9:41 pmDes Moines
Mar 2
DSM6:55 pmDes Moines
3h 54m
1 stop
LEX11:49 pmLexington Blue Grass
$310
United Airlines
Feb 14
LEX2:03 pmLexington Blue Grass
4h 44m
1 stop
DSM5:47 pmDes Moines
Feb 18
DSM6:55 pmDes Moines
3h 54m
1 stop
LEX11:49 pmLexington Blue Grass
$379

momondo Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/25

10:35 am-2:27 pm

1 stop4h 52m

Des Moines

Sat 2/28

6:55 pm-11:49 pm

1 stop3h 54m

$269

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 3/6

5:07 pm-10:20 pm

1 stop6h 13m

Des Moines

Sat 3/7

5:00 am-2:33 pm

2 stops8h 33m

$274

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sat 2/28

5:00 am-1:05 pm

2 stops9h 05m

Des Moines

Mon 3/2

5:00 am-9:28 am

1 stop3h 28m

$305

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/25

5:00 am-1:05 pm

2 stops9h 05m

Des Moines

Sat 2/28

5:00 am-9:28 am

1 stop3h 28m

$309

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sat 2/28

5:45 pm-9:41 pm

1 stop4h 56m

Des Moines

Mon 3/2

6:55 pm-11:49 pm

1 stop3h 54m

$310

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/25

5:00 am-1:05 pm

2 stops9h 05m

Des Moines

Sat 2/28

5:00 am-2:33 pm

2 stops8h 33m

$314

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

10:27 am-11:40 pm

1 stop14h 13m

Des Moines

Sat 2/28

5:00 am-9:28 am

1 stop3h 28m

$332

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

5:07 pm-11:40 pm

1 stop7h 33m

Des Moines

Sat 2/28

5:00 am-2:33 pm

2 stops8h 33m

$337

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

10:35 am-2:27 pm

1 stop4h 52m

Des Moines

Sat 2/28

3:24 pm-8:09 pm

1 stop3h 45m

$383

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

10:27 am-11:40 pm

1 stop14h 13m

Des Moines

Sat 2/28

5:00 am-2:33 pm

2 stops8h 33m

$397

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Des Moines from

How to get the cheapest flight ticket from Lexington to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Des Moines?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Des Moines from Lexington according to our data. American Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 3 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When to book flights from Lexington to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Lexington to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Lexington to Des Moines (LEX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Lexington to Des Moines

Fastest flight time

4h 14m

Direct flights

None
The fastest flight from Lexington to Des Moines takes 4h 14m
There are no direct flights from Lexington to Des Moines. There are no popular flight routes from Lexington to Des Moines.
Search flight deals

  • How far is Lexington Blue Grass to Des Moines by plane?

    The distance between Lexington Blue Grass and Des Moines is about 542.1 mi. By plane, this route typically takes 4h 14m.

  • When did momondo last update prices for flights from Lexington Blue Grass Airport to Des Moines Airport?

    Prices for flights from Lexington Blue Grass Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Lexington Blue Grass Airport to Des Moines Airport?

  • How old do you have to be to fly from Lexington Blue Grass Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lexington Blue Grass Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Lexington to Des Moines?

Best airlines flying from Lexington to Des Moines

Compare and see reviews for airlines that fly from Lexington to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Lexington to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Lexington.

Can I find flights from Lexington to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Lexington on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Lexington to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Lexington.

I’m not ready to book a flight from Lexington to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Lexington to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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