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Cheap flights from Knoxville to Mexico City Federal District from $299

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Mexico City Federal District departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Mexico City Federal District

Cheap round-trip flights

Multiple Airlines Logo
11:23 am - 10:00 pmTYS-MEX
36h 37m2 stops
Multiple Airlines Logo
8:10 am - 7:32 pmMEX-TYS
9h 22m1 stop
$467Multiple Airlines
Find Deal
Tue, Oct 21 - Mon, Oct 27
Multiple Airlines Logo
11:23 am - 7:35 pmTYS-MEX
34h 12m2 stops
Multiple Airlines Logo
8:10 am - 7:32 pmMEX-TYS
9h 22m1 stop
$494Multiple Airlines
Find Deal
Tue, Oct 14 - Sun, Oct 19
Multiple Airlines Logo
7:17 pm - 5:05 pmTYS-MEX
23h 48m1 stop
Multiple Airlines Logo
10:00 pm - 11:14 pmMEX-TYS
24h 14m2 stops
$507Multiple Airlines
Find Deal
Thu, Oct 30 - Sun, Nov 9
Multiple Airlines Logo
7:17 pm - 5:05 pmTYS-MEX
23h 48m1 stop
Multiple Airlines Logo
6:10 pm - 6:37 pmMEX-TYS
23h 27m1 stop
$525Multiple Airlines
Find Deal
Thu, Oct 30 - Sun, Nov 9
Delta Logo
10:05 am - 2:15 pmTYS-MEX
6h 10m1 stop
Delta Logo
3:45 pm - 11:44 pmMEX-TYS
5h 59m1 stop
$562Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
Delta Logo
5:30 am - 12:20 pmTYS-MEX
8h 50m2 stops
Delta Logo
3:45 pm - 11:44 pmMEX-TYS
5h 59m1 stop
$567Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
7:15 am - 10:45 amTYS-MEX
5h 30m1 stop
United Airlines Logo
6:30 am - 6:10 pmMEX-TYS
9h 40m1 stop
$572United Airlines
Find Deal
Tue, Oct 14 - Sun, Oct 19
American Airlines Logo
5:49 am - 8:40 pmTYS-MEX
16h 51m1 stop
American Airlines Logo
12:40 pm - 10:10 pmMEX-TYS
7h 30m1 stop
$582American Airlines
Find Deal
Sun, Mar 8 - Wed, Mar 11
American Airlines Logo
6:56 am - 12:25 pmTYS-MEX
6h 29m1 stop
American Airlines Logo
5:54 am - 3:40 pmMEX-TYS
8h 46m2 stops
$587American Airlines
Find Deal
Sun, Feb 15 - Fri, Feb 20
United Airlines Logo
11:42 am - 6:55 pmTYS-MEX
8h 13m1 stop
United Airlines Logo
7:50 am - 11:44 pmMEX-TYS
14h 54m1 stop
$672United Airlines
Find Deal
Wed, Dec 3 - Sun, Dec 14

American Airlines flights from Knoxville to Mexico City Federal District

Our best American Airlines deals on Knoxville to Mexico City Federal District flight tickets
American Airlines
Mar 8
TYS5:49 amKnoxville McGhee Tyson
16h 51m
1 stop
MEX8:40 pmMexico City Benito Juarez
Mar 11
MEX12:40 pmMexico City Benito Juarez
7h 30m
1 stop
TYS10:10 pmKnoxville McGhee Tyson
$582
Find similar
American Airlines
Feb 15
TYS6:56 amKnoxville McGhee Tyson
6h 29m
1 stop
MEX12:25 pmMexico City Benito Juarez
Feb 20
MEX5:54 amMexico City Benito Juarez
8h 46m
2 stops
TYS3:40 pmKnoxville McGhee Tyson
$587
Find similar
American Airlines
Nov 18
TYS6:05 amKnoxville McGhee Tyson
7h 40m
1 stop
MEX12:45 pmMexico City Benito Juarez
Jan 7
MEX11:20 amMexico City Benito Juarez
9h 15m
1 stop
TYS9:35 pmKnoxville McGhee Tyson
$592
Find similar

United Airlines flights from Knoxville to Mexico City Federal District

Our best United Airlines deals on Knoxville to Mexico City Federal District flight tickets
United Airlines
Oct 14
TYS7:15 amKnoxville McGhee Tyson
5h 30m
1 stop
MEX10:45 amMexico City Benito Juarez
Oct 19
MEX6:30 amMexico City Benito Juarez
9h 40m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$572
Find similar
United Airlines
Dec 3
TYS11:42 amKnoxville McGhee Tyson
8h 13m
1 stop
MEX6:55 pmMexico City Benito Juarez
Dec 14
MEX7:50 amMexico City Benito Juarez
14h 54m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$672
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 18, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 10/21

11:23 am-10:00 pm

2 stops36h 37m

Mexico City Benito Juarez

Mon 10/27

8:10 am-7:32 pm

1 stop9h 22m

$467

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 10/14

11:23 am-7:35 pm

2 stops34h 12m

Mexico City Benito Juarez

Sun 10/19

8:10 am-7:32 pm

1 stop9h 22m

$494

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-5:05 pm

1 stop23h 48m

Mexico City Benito Juarez

Sun 11/9

10:00 pm-11:14 pm

2 stops24h 14m

$507

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-5:05 pm

1 stop23h 48m

Mexico City Benito Juarez

Sun 11/9

6:10 pm-6:37 pm

1 stop23h 27m

$525

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/10

10:05 am-2:15 pm

1 stop6h 10m

Mexico City Benito Juarez

Wed 3/11

3:45 pm-11:44 pm

1 stop5h 59m

$562

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/10

5:30 am-12:20 pm

2 stops8h 50m

Mexico City Benito Juarez

Wed 3/11

3:45 pm-11:44 pm

1 stop5h 59m

$567

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 10/14

7:15 am-10:45 am

1 stop5h 30m

Mexico City Benito Juarez

Sun 10/19

6:30 am-6:10 pm

1 stop9h 40m

$572

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 3/8

5:49 am-8:40 pm

1 stop16h 51m

Mexico City Benito Juarez

Wed 3/11

12:40 pm-10:10 pm

1 stop7h 30m

$582

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 2/15

6:56 am-12:25 pm

1 stop6h 29m

Mexico City Benito Juarez

Fri 2/20

5:54 am-3:40 pm

2 stops8h 46m

$587

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 12/3

11:42 am-6:55 pm

1 stop8h 13m

Mexico City Benito Juarez

Sun 12/14

7:50 am-11:44 pm

1 stop14h 54m

$672

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Knoxville to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of April, then departing from Knoxville during the month August is also very affordable. Most momondo users find prices during this month for around $546.

What is the cheapest day to depart on your flight to Mexico City Federal District?

The cheapest day to depart on your flight to Mexico City Federal District is on a Wednesday when prices can be found for as low as $657. This is often the case because there is less demand to fly during this day of the week. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Mexico City Federal District for around $798.

What is the cheapest time of day to depart on your flight to Mexico City Federal District?

The cheapest time of day to fly to Mexico City Federal District is at noon when flights can be purchased for as low as $678. In the afternoon is when there is more demand to fly to Mexico City Federal District, so prices are often more expensive at around $884 per ticket.

Cheap Knoxville to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Mexico City Federal District

Direct flights

None
There are no direct flights from Knoxville to Mexico City Federal District. There are no popular flight routes from Knoxville to Mexico City Federal District.
Search flight deals

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico City Federal District?

    Prices for flights from Knoxville McGhee Tyson Airport to Mexico City Federal District are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico City Federal District?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico City Federal District?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The travel and health documents required for your trip to Mexico City Federal District can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico City Federal District. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Mexico City Federal District

Compare and see reviews for airlines that fly from Knoxville to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $455Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $462Free CancellationRating
7.9
7,964 reviews
Search Delta flights
AeromexicoPriceFrom $487Free CancellationRating
7.4
1,697 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Mexico City Federal District?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Mexico City Federal District. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Mexico City Federal District with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Mexico City Federal District flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Mexico City Federal District?

momondo helps you find the best flight between Knoxville and Mexico City Federal District by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Mexico City Federal District right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Mexico City Federal District flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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