What is the cheapest airline that flies from Knoxville McGhee Tyson to Italy?

Lufthansa, American Airlines, and Air Canada are the most popular carriers operating from Knoxville McGhee Tyson to Italy

What airlines fly to Italy?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Italy from Knoxville according to our data. Delta is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 7 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Italy?

Prices for flights from Knoxville McGhee Tyson Airport to Italy are refreshed on a daily basis.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Italy?

As of December 2025, there are 5 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Italy.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Italy?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents you'll need for your trip to Italy may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Italy. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$307 Cheap Flights from Knoxville to Italy in 2025/26

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Find the cheapest flights from Knoxville to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:59 pm - 1:25 pm

TYS

FCO

17h 26m2 stops

11:00 am - 7:27 pm

FCO

TYS

14h 27m1 stop

$448Lufthansa

Mon, Feb 2 - Mon, Feb 9

5:29 pm - 9:55 am

TYS

MXP

34h 26m2 stops

1:05 pm - 8:52 pm

MXP

TYS

37h 47m2 stops

$474United Airlines

Wed, Feb 4 - Tue, Feb 10

10:07 am - 9:45 am

TYS

MXP

17h 38m2 stops

11:05 am - 11:08 am

MXP

TYS

30h 03m1 stop

$481Delta

Wed, Jan 28 - Sun, Feb 8

2:25 pm - 4:30 pm

TYS

FLR

20h 05m2 stops

10:20 am - 7:27 pm

FLR

TYS

15h 07m2 stops

$484Multiple Airlines

Sun, Jan 18 - Sun, Jan 25

4:06 pm - 9:05 am

TYS

MXP

10h 59m1 stop

11:05 am - 7:59 pm

MXP

TYS

14h 54m1 stop

$491Delta

Mon, Feb 2 - Tue, Feb 10

2:25 pm - 10:05 am

TYS

LIN

13h 40m2 stops

9:45 am - 7:27 pm

LIN

TYS

15h 42m2 stops

$492Multiple Airlines

Wed, Jan 28 - Sun, Feb 8

2:19 pm - 1:20 pm

TYS

VCE

17h 01m2 stops

6:55 am - 8:56 pm

VCE

TYS

20h 01m2 stops

$493British Airways

Sun, Jan 18 - Sun, Jan 25

7:44 am - 11:30 am

TYS

LIN

21h 46m2 stops

7:20 am - 8:56 pm

LIN

TYS

19h 36m2 stops

$495British Airways

Sun, Feb 1 - Sun, Feb 8

2:37 pm - 2:40 pm

TYS

CTA

18h 03m2 stops

3:25 pm - 11:45 pm

CTA

TYS

38h 20m2 stops

$591KLM

Mon, Feb 2 - Mon, Feb 9

12:03 pm - 8:55 am

TYS

VCE

14h 52m1 stop

11:05 am - 8:05 pm

VCE

TYS

15h 00m1 stop

$841KLM

Mon, Mar 30 - Sun, Apr 5

British Airways flights from Knoxville to Italy

Our best British Airways deals on Knoxville to Italy flight tickets

British Airways

Jan 18

TYS2:19 pmKnoxville McGhee Tyson

17h 01m

2 stops

VCE1:20 pmVenice Marco Polo

Jan 25

VCE6:55 amVenice Marco Polo

20h 01m

2 stops

TYS8:56 pmKnoxville McGhee Tyson

$493

Find similar

British Airways

Feb 1

TYS7:44 amKnoxville McGhee Tyson

21h 46m

2 stops

LIN11:30 amMilan Linate

Feb 8

LIN7:20 amMilan Linate

19h 36m

2 stops

TYS8:56 pmKnoxville McGhee Tyson

$495

Find similar

British Airways

Mar 11

TYS6:10 amKnoxville McGhee Tyson

24h 20m

2 stops

LIN11:30 amMilan Linate

Mar 21

LIN8:30 pmMilan Linate

29h 35m

2 stops

TYS9:05 pmKnoxville McGhee Tyson

$570

Find similar

Air Canada flights from Knoxville to Italy

Our best Air Canada deals on Knoxville to Italy flight tickets

Air Canada

Feb 3

TYS9:30 amKnoxville McGhee Tyson

18h 35m

3 stops

VCE10:05 amVenice Marco Polo

Feb 10

VCE6:45 amVenice Marco Polo

18h 42m

3 stops

TYS7:27 pmKnoxville McGhee Tyson

$522

Find similar

Air Canada

Mar 3

TYS9:40 amKnoxville McGhee Tyson

41h 15m

2 stops

FCO8:55 amRome Fiumicino

Mar 15

FCO12:15 pmRome Fiumicino

31h 35m

2 stops

TYS2:50 pmKnoxville McGhee Tyson

$524

Find similar

Air Canada

Feb 3

TYS2:25 pmKnoxville McGhee Tyson

17h 50m

3 stops

LIN2:15 pmMilan Linate

Feb 10

LIN6:15 amMilan Linate

19h 12m

3 stops

TYS7:27 pmKnoxville McGhee Tyson

$527

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 2/2

1:59 pm-1:25 pm

2 stops17h 26m

Rome Fiumicino

Mon 2/9

11:00 am-7:27 pm

1 stop14h 27m

$448

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 2/4

5:29 pm-9:55 am

2 stops34h 26m

Milan Malpensa

Tue 2/10

1:05 pm-8:52 pm

2 stops37h 47m

$474

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 1/28

10:07 am-9:45 am

2 stops17h 38m

Milan Malpensa

Sun 2/8

11:05 am-11:08 am

1 stop30h 03m

$481

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sun 1/18

2:25 pm-4:30 pm

2 stops20h 05m

Florence Peretola

Sun 1/25

10:20 am-7:27 pm

2 stops15h 07m

$484

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Mon 2/2

4:06 pm-9:05 am

1 stop10h 59m

Milan Malpensa

Tue 2/10

11:05 am-7:59 pm

1 stop14h 54m

$491

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Wed 1/28

2:25 pm-10:05 am

2 stops13h 40m

Milan Linate

Sun 2/8

9:45 am-7:27 pm

2 stops15h 42m

$492

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Sun 1/18

2:19 pm-1:20 pm

2 stops17h 01m

Venice Marco Polo

Sun 1/25

6:55 am-8:56 pm

2 stops20h 01m

$493

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Sun 2/1

7:44 am-11:30 am

2 stops21h 46m

Milan Linate

Sun 2/8

7:20 am-8:56 pm

2 stops19h 36m

$495

KnoxvilleCatania

TYS - CTA

TYSCTA

Knoxville McGhee Tyson

Mon 2/2

2:37 pm-2:40 pm

2 stops18h 03m

Catania Fontanarossa

Mon 2/9

3:25 pm-11:45 pm

2 stops38h 20m

$591

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Mon 3/30

12:03 pm-8:55 am

1 stop14h 52m

Venice Marco Polo

Sun 4/5

11:05 am-8:05 pm

1 stop15h 00m

$841

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Knoxville is in December. Flight prices, which tend to average around $705, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to Italy from Knoxville during November instead. Flights to Italy in November, while not as cheap as those in December, still average around $758.

What is the cheapest day to depart on your flight to Italy?

According to our data, Wednesday is the cheapest day to fly to Italy from Knoxville. The lowest ticket price found for a Wednesday departure recently was $1,088. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Italy for around $1,292.

What is the cheapest time of day to depart on your flight to Italy?

Our data shows that the cheapest Knoxville to Italy flights are usually those with departure times in the afternoon. Our users have found flights to Italy in the afternoon for as low as $1,092. In contrast, the most expensive time of day to depart to Italy is at noon when prices are around $1,320.

Can stopping save me money on Knoxville to Italy flights?

You could potentially save up to 26% on your flight if you consider stops on a Knoxville to Italy flight.

Cheap Knoxville to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Italy

Fastest flight time	11h 42m
Direct flights	None

The fastest flight from Knoxville to Italy takes 11h 42m

There are no direct flights from Knoxville to Italy. There are no popular flight routes from Knoxville to Italy.

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Italy?
Prices for flights from Knoxville McGhee Tyson Airport to Italy are refreshed on a daily basis.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Italy?
As of December 2025, there are 5 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Italy.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Italy?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents you'll need for your trip to Italy may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Italy. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Knoxville to Italy

Compare and see reviews for airlines that fly from Knoxville to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $500	Free Cancellation	Rating 7.4 9,100 reviews	Search United Airlines flights
American Airlines	PriceFrom $583	Free Cancellation	Rating 7.2 11,051 reviews	Search American Airlines flights
Delta	PriceFrom $612	Free Cancellation	Rating 7.9 8,017 reviews	Search Delta flights
Lufthansa	PriceFrom $649	Free Cancellation	Rating 6.8 7,640 reviews	Search Lufthansa flights
British Airways	PriceFrom $765	Free Cancellation	Rating 6.7 7,602 reviews	Search British Airways flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Italy?

It is quick and easy to find Knoxville to Italy flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Italy that suits you.

Can I find flights from Knoxville to Italy with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Italy flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Italy?

momondo provides multiple filters to help you find the best flight to Italy from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Italy right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Italy now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Italy and let you know when they change.