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Cheap flights from Knoxville to Cancún from $244

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Cancún departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Cancún

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:55 am - 5:00 pm-
9h 05m
Southwest Logo
11:20 am - 9:35 pm-
10h 15m
$488Southwest
Tue, Nov 17 - Sat, Nov 21
Southwest Logo
7:00 am - 7:45 pm-
12h 45m
Southwest Logo
10:45 am - 10:40 pm-
11h 55m
$492Southwest
Tue, Nov 17 - Sat, Nov 21
American Airlines Logo
6:05 am - 3:25 pm-
10h 20m
American Airlines Logo
3:37 pm - 9:44 am-
17h 07m
$514American Airlines
Mon, Sep 21 - Fri, Sep 25
Multiple Airlines Logo
7:00 am - 11:58 pm-
17h 58m
Multiple Airlines Logo
10:23 am - 3:32 pm-
28h 09m
$532Multiple Airlines
Thu, Aug 27 - Thu, Sep 3
American Airlines Logo
6:05 am - 3:25 pm-
10h 20m
American Airlines Logo
2:37 pm - 10:50 pm-
7h 13m
$546American Airlines
Mon, Sep 14 - Mon, Sep 21
Aeromexico Logo
5:40 am - 7:50 pm-
15h 10m
Aeromexico Logo
7:01 am - 11:55 pm-
15h 54m
$561Aeromexico
Mon, Sep 21 - Fri, Sep 25
Delta Logo
2:40 pm - 9:10 pm-
6h 30m
Delta Logo
11:20 am - 11:57 pm-
12h 37m
$568Delta
Mon, Dec 7 - Fri, Dec 11
Delta Logo
2:40 pm - 9:10 pm-
6h 30m
Delta Logo
1:40 pm - 11:57 pm-
10h 17m
$568Delta
Mon, Dec 7 - Fri, Dec 11
Aeromexico Logo
7:10 am - 3:30 pm-
8h 20m
Aeromexico Logo
1:40 pm - 11:57 pm-
10h 17m
$568Aeromexico
Mon, Dec 7 - Fri, Dec 11
Multiple Airlines Logo
7:00 am - 11:58 pm-
17h 58m
Multiple Airlines Logo
10:23 am - 1:40 pm-
26h 17m
$638Multiple Airlines
Thu, Sep 3 - Sun, Sep 6

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Delta flights from Knoxville to Cancún

Our best Delta deals on Knoxville to Cancún flight tickets
Delta
Dec 7
TYS2:40 pmKnoxville McGhee Tyson
6h 30m
1 stop
CUN9:10 pmCancun
Dec 11
CUN1:40 pmCancun
10h 17m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
$568
Delta
Oct 19
TYS5:40 amKnoxville McGhee Tyson
8h 35m
1 stop
CUN1:15 pmCancun
Oct 26
CUN12:20 pmCancun
10h 39m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$593
Delta
Sep 26
TYS1:31 pmKnoxville McGhee Tyson
7h 19m
1 stop
CUN7:50 pmCancun
Oct 1
CUN12:40 pmCancun
10h 15m
2 stops
TYS11:55 pmKnoxville McGhee Tyson
$594

American Airlines flights from Knoxville to Cancún

Our best American Airlines deals on Knoxville to Cancún flight tickets
American Airlines
Sep 21
TYS6:05 amKnoxville McGhee Tyson
10h 20m
1 stop
CUN3:25 pmCancun
Sep 25
CUN3:37 pmCancun
17h 07m
1 stop
TYS9:44 amKnoxville McGhee Tyson
$514
American Airlines
Sep 14
TYS6:05 amKnoxville McGhee Tyson
10h 20m
1 stop
CUN3:25 pmCancun
Sep 21
CUN2:37 pmCancun
7h 13m
1 stop
TYS10:50 pmKnoxville McGhee Tyson
$546
American Airlines
Sep 14
TYS6:15 amKnoxville McGhee Tyson
7h 52m
2 stops
CUN1:07 pmCancun
Sep 21
CUN3:37 pmCancun
6h 13m
1 stop
TYS10:50 pmKnoxville McGhee Tyson
$550

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Cancún that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Knoxville to Cancún that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 11/17

7:55 am-5:00 pm

1 stop9h 05m

Cancun

Sat 11/21

11:20 am-9:35 pm

1 stop10h 15m

$488

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 11/17

7:00 am-7:45 pm

2 stops12h 45m

Cancun

Sat 11/21

10:45 am-10:40 pm

2 stops11h 55m

$492

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 9/21

6:05 am-3:25 pm

1 stop10h 20m

Cancun

Fri 9/25

3:37 pm-9:44 am

1 stop17h 07m

$514

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 8/27

7:00 am-11:58 pm

2 stops17h 58m

Cancun

Thu 9/3

10:23 am-3:32 pm

1 stop28h 09m

$532

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 9/14

6:05 am-3:25 pm

1 stop10h 20m

Cancun

Mon 9/21

2:37 pm-10:50 pm

1 stop7h 13m

$546

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 9/21

5:40 am-7:50 pm

1 stop15h 10m

Cancun

Fri 9/25

7:01 am-11:55 pm

2 stops15h 54m

$561

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 12/7

2:40 pm-9:10 pm

1 stop6h 30m

Cancun

Fri 12/11

11:20 am-11:57 pm

2 stops12h 37m

$568
Quickest round-trip

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 12/7

2:40 pm-9:10 pm

1 stop6h 30m

Cancun

Fri 12/11

1:40 pm-11:57 pm

1 stop10h 17m

$568

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 12/7

7:10 am-3:30 pm

1 stop8h 20m

Cancun

Fri 12/11

1:40 pm-11:57 pm

1 stop10h 17m

$568

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 9/3

7:00 am-11:58 pm

2 stops17h 58m

Cancun

Sun 9/6

10:23 am-1:40 pm

1 stop26h 17m

$638

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cancún from

How to get the cheapest flight ticket from Knoxville to Cancún

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Cancún?

Prices are currently low for flights on this route.

Typical prices usually range from $573 to $771.
The lowest price recently found on this route was $488.

What is the cheapest month to fly to Cancún?

If you don’t want to visit Cancún in April, then you should wait until December to fly from Knoxville, when ticket prices are also cheap, with an average price of $589.

How far in advance should I book a flight from Knoxville to Cancún?

You are more likely to see cheaper flights to Cancún from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Cancún for around $651 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cancún from Knoxville for as low as $584 on momondo.

When to book flights from Knoxville to Cancún

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Cancún according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Cancún (TYS to CUN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Cancún

Fastest flight time

5h 30m

Direct flights

None
The fastest flight from Knoxville to Cancún takes 5h 30m
There are no direct flights from Knoxville to Cancún. There are no popular flight routes from Knoxville to Cancún.
Search flight deals

Frequently asked questions about flying from Knoxville to Cancún

  • How far is Knoxville McGhee Tyson to Cancun by plane?

    Cancun is 1037.1 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 5h 30m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Cancun Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Cancun Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Cancun Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Cancun Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Cancun Airport.

  • What documentation or ID do you need to fly to Cancun Airport?

    The travel and health documents you'll need for your trip to Cancun Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cancun Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Cancún?

Best airlines flying from Knoxville to Cancún

Compare and see reviews for airlines that fly from Knoxville to Cancún with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $428Free CancellationRating
7.8
8,482 reviews
Search Delta flights
United AirlinesPriceFrom $473Free CancellationRating
7.4
10,059 reviews
Search United Airlines flights
AeromexicoPriceFrom $509Free CancellationRating
7.4
1,471 reviews
Search Aeromexico flights
American AirlinesPriceFrom $518Free CancellationRating
7.1
11,845 reviews
Search American Airlines flights
SouthwestPriceFrom $534Free CancellationRating
8.0
4,221 reviews
Search Southwest flights

Traveling to a place near Cancún?

Book flights to Cancún if you plan to visit one of these locations
Playa del Carmen
Isla Mujeres
Puerto Morelos
Holbox
Akumal
Puerto Aventuras
Punta Sam
Valladolid

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Cancún?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Cancún. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Cancún with flexible booking policies on momondo?

Flights from Knoxville to Cancún with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Cancún?

momondo helps you find the best flight between Knoxville and Cancún by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Cancún right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Cancún, momondo offers a useful price alert feature which will track prices for flights to Cancún from Knoxville and alert you when they change.

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