What is the cheapest airline that flies from Key West to Buffalo?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Key West to Buffalo

When did momondo last update prices for flights from Key West Airport to Buffalo Airport?

Prices for flights from Key West Airport to Buffalo Airport refresh daily.

How many operators does momondo search for flights from Key West Airport to Buffalo Airport?

As of October 2025, there are 2 operators available to choose from for flights from Key West Airport to Buffalo Airport.

How old do you have to be to fly from Key West Airport to Buffalo Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$172 Cheap Flights from Key West to Buffalo in 2025/26

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Find the cheapest flights from Key West to Buffalo

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 5:26 pmEYW-BUF

10h 26m2 stops

12:09 pm - 5:13 pmBUF-EYW

5h 04m1 stop

$299Delta

Find Deal

Thu, Feb 19 - Mon, Feb 23

10:59 am - 7:34 pmEYW-BUF

8h 35m1 stop

5:24 pm - 11:05 amBUF-EYW

17h 41m2 stops

$303Multiple Airlines

Find Deal

Thu, Oct 23 - Mon, Oct 27

7:00 am - 5:26 pmEYW-BUF

10h 26m2 stops

10:20 am - 7:44 pmBUF-EYW

9h 24m2 stops

$304Delta

Find Deal

Thu, Feb 19 - Mon, Feb 23

3:12 pm - 10:42 pmEYW-BUF

7h 30m1 stop

6:00 am - 1:52 pmBUF-EYW

7h 52m1 stop

$319United Airlines

Find Deal

Thu, Oct 23 - Mon, Oct 27

7:00 am - 5:26 pmEYW-BUF

10h 26m2 stops

10:30 am - 7:44 pmBUF-EYW

9h 14m2 stops

$324Delta

Find Deal

Thu, Feb 19 - Mon, Feb 23

12:22 pm - 11:56 pmEYW-BUF

11h 34m2 stops

6:03 am - 5:21 pmBUF-EYW

11h 18m2 stops

$329Delta

Find Deal

Thu, Oct 23 - Mon, Oct 27

10:47 am - 8:58 amEYW-BUF

22h 11m2 stops

12:20 pm - 8:15 amBUF-EYW

19h 55m1 stop

$395Multiple Airlines

Find Deal

Sat, Nov 22 - Sun, Nov 30

3:00 pm - 10:58 pmEYW-BUF

7h 58m1 stop

6:25 am - 1:46 pmBUF-EYW

7h 21m1 stop

$424United Airlines

Find Deal

Sat, Nov 22 - Sun, Nov 30

5:20 pm - 12:07 amEYW-BUF

6h 47m1 stop

12:05 pm - 6:23 pmBUF-EYW

6h 18m1 stop

$456American Airlines

Find Deal

Thu, Feb 19 - Mon, Feb 23

4:47 pm - 12:08 amEYW-BUF

7h 21m2 stops

5:00 am - 1:03 pmBUF-EYW

8h 03m2 stops

$553American Airlines

Find Deal

Sat, Nov 22 - Sun, Nov 30

American Airlines flights from Key West to Buffalo

Our best American Airlines deals on Key West to Buffalo flight tickets

American Airlines

Feb 19

EYW5:20 pmKey West

6h 47m

1 stop

BUF12:07 amBuffalo

Feb 23

BUF12:05 pmBuffalo

6h 18m

1 stop

EYW6:23 pmKey West

$456

Find similar

American Airlines

Nov 22

EYW4:47 pmKey West

7h 21m

2 stops

BUF12:08 amBuffalo

Nov 30

BUF5:00 amBuffalo

8h 03m

2 stops

EYW1:03 pmKey West

$553

Find similar

Delta flights from Key West to Buffalo

Our best Delta deals on Key West to Buffalo flight tickets

Delta

Feb 19

EYW7:00 amKey West

10h 26m

2 stops

BUF5:26 pmBuffalo

Feb 23

BUF12:09 pmBuffalo

5h 04m

1 stop

EYW5:13 pmKey West

$299

Find similar

Delta

Feb 19

EYW7:00 amKey West

10h 26m

2 stops

BUF5:26 pmBuffalo

Feb 23

BUF10:20 amBuffalo

9h 24m

2 stops

EYW7:44 pmKey West

$304

Find similar

Delta

Feb 19

EYW7:00 amKey West

10h 26m

2 stops

BUF5:26 pmBuffalo

Feb 23

BUF10:30 amBuffalo

9h 14m

2 stops

EYW7:44 pmKey West

$324

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

7:00 am-5:26 pm

2 stops10h 26m

Buffalo

Mon 2/23

12:09 pm-5:13 pm

1 stop5h 04m

$299

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 10/23

10:59 am-7:34 pm

1 stop8h 35m

Buffalo

Mon 10/27

5:24 pm-11:05 am

2 stops17h 41m

$303

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

7:00 am-5:26 pm

2 stops10h 26m

Buffalo

Mon 2/23

10:20 am-7:44 pm

2 stops9h 24m

$304

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 10/23

3:12 pm-10:42 pm

1 stop7h 30m

Buffalo

Mon 10/27

6:00 am-1:52 pm

1 stop7h 52m

$319

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

7:00 am-5:26 pm

2 stops10h 26m

Buffalo

Mon 2/23

10:30 am-7:44 pm

2 stops9h 14m

$324

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 10/23

12:22 pm-11:56 pm

2 stops11h 34m

Buffalo

Mon 10/27

6:03 am-5:21 pm

2 stops11h 18m

$329

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sat 11/22

10:47 am-8:58 am

2 stops22h 11m

Buffalo

Sun 11/30

12:20 pm-8:15 am

1 stop19h 55m

$395

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sat 11/22

3:00 pm-10:58 pm

1 stop7h 58m

Buffalo

Sun 11/30

6:25 am-1:46 pm

1 stop7h 21m

$424

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

5:20 pm-12:07 am

1 stop6h 47m

Buffalo

Mon 2/23

12:05 pm-6:23 pm

1 stop6h 18m

$456

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sat 11/22

4:47 pm-12:08 am

2 stops7h 21m

Buffalo

Sun 11/30

5:00 am-1:03 pm

2 stops8h 03m

$553

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Key West to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Friday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $352. Flights from Key West to Buffalo on a Sunday will generally be more expensive and average around $755. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Key West to Buffalo when you can find flight prices for as low as $388. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Buffalo, so prices are often more expensive at around $554 per ticket.

When to book flights from Key West to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Buffalo according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Key West to Buffalo (EYW to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Buffalo

Direct flights	None

There are no direct flights from Key West to Buffalo. There are no popular flight routes from Key West to Buffalo.

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How far is Key West to Buffalo by plane?
Buffalo is 1276.6 mi away from Key West. A reasonable flight in good conditions will take 5h 57m.
When did momondo last update prices for flights from Key West Airport to Buffalo Airport?
Prices for flights from Key West Airport to Buffalo Airport refresh daily.
How many operators does momondo search for flights from Key West Airport to Buffalo Airport?
As of October 2025, there are 2 operators available to choose from for flights from Key West Airport to Buffalo Airport.
How old do you have to be to fly from Key West Airport to Buffalo Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Key West to Buffalo?
momondo data reveals that the most frequently booked airline on the route from Key West to Buffalo is Delta, representing 52% of all bookings. The subsequent popular airline is American Airlines at 48%.

Best airlines flying from Key West to Buffalo

Compare and see reviews for airlines that fly from Key West to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $259	Free Cancellation	Rating 7.9 7,968 reviews		Search Delta flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.2 11,041 reviews		Search American Airlines flights

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Tonawanda

Amherst

Williamsville

Grand Island

Orchard Park

Lockport

West Seneca

East Aurora

Bowmansville

Eden

Angola

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Why should I use momondo to find a flight deal from Key West to Buffalo?

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Can I find flights from Key West to Buffalo with flexible booking policies on momondo?

All flight searches from Key West to Buffalo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Key West to Buffalo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Key West to Buffalo.

I’m not ready to book a flight from Key West to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.