What airlines fly to South America?

Spirit Airlines, American Airlines and Delta are the top three most popular airlines that fly to South America from Columbus Airport according to our data. Spirit Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Columbus to South America?

Spirit Airlines, American Airlines, and Air Canada are the most popular carriers operating from Columbus to South America

When did momondo last update prices for flights from Columbus Airport to South America?

Prices for flights from Columbus Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Columbus Airport to South America?

There are 5 operators available for flights from Columbus Airport to South America as of May 2026.

How old do you have to be to fly from Columbus Airport to South America?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Columbus Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$166 Cheap Flights from Columbus Airport to South America in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbus Airport to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:26 pm

CMH

CTG

7h 26m

1 stop

1:31 pm - 11:56 pm

CTG

CMH

9h 25m

1 stop

$412Spirit Airlines

Sun, May 17 - Thu, May 21

6:00 am - 12:26 pm

CMH

CTG

7h 26m

1 stop

1:31 pm - 11:56 pm

CTG

CMH

9h 25m

1 stop

$429Spirit Airlines

Sun, May 17 - Fri, May 22

10:00 am - 7:15 pm

CMH

BOG

10h 15m

1 stop

2:55 pm - 12:44 am

BOG

CMH

8h 49m

1 stop

$605LATAM Airlines

Tue, Jul 14 - Wed, Jul 22

8:11 am - 8:10 pm

CMH

BOG

12h 59m

2 stops

11:00 am - 12:44 am

BOG

CMH

12h 44m

2 stops

$610Delta

Tue, Jul 14 - Wed, Jul 22

5:45 am - 10:30 pm

CMH

BOG

17h 45m

1 stop

6:30 am - 10:39 pm

BOG

CMH

15h 09m

1 stop

$617American Airlines

Tue, Jul 14 - Tue, Jul 21

6:00 am - 8:10 pm

CMH

BOG

15h 10m

2 stops

11:00 am - 11:56 pm

BOG

CMH

11h 56m

2 stops

$630Delta

Fri, Aug 14 - Sun, Aug 23

5:01 pm - 5:00 am

CMH

UIO

12h 59m

1 stop

12:35 am - 11:02 am

UIO

CMH

9h 27m

1 stop

$696United Airlines

Mon, Aug 10 - Sun, Aug 23

12:05 pm - 6:45 am

CMH

LIM

19h 40m

1 stop

12:05 pm - 11:55 pm

LIM

CMH

10h 50m

1 stop

$699LATAM Airlines

Sun, Oct 4 - Tue, Oct 20

6:30 am - 11:25 pm

CMH

UIO

17h 55m

1 stop

7:25 am - 8:35 am

UIO

CMH

24h 10m

2 stops

$701United Airlines

Mon, Aug 10 - Mon, Aug 24

5:08 am - 1:31 pm

CMH

GYE

9h 23m

1 stop

6:00 am - 12:37 am

GYE

CMH

17h 37m

1 stop

$707American Airlines

Tue, Jun 9 - Thu, Jul 30

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Air Canada flights from Columbus Airport to South America

Our best Air Canada deals on Columbus Airport to South America flight tickets

Air Canada

Jul 9

CMH9:55 amColumbus

19h 10m

2 stops

BOG4:05 amBogotá El Dorado

Aug 9

BOG9:00 amBogotá El Dorado

27h 32m

1 stop

CMH1:32 pmColumbus

$760

Air Canada

Jul 9

CMH9:55 amColumbus

19h 10m

2 stops

BOG4:05 amBogotá El Dorado

Aug 9

BOG9:00 amBogotá El Dorado

29h 22m

2 stops

CMH3:22 pmColumbus

$763

Air Canada

May 17

CMH2:15 pmColumbus

14h 50m

2 stops

BOG4:05 amBogotá El Dorado

May 21

BOG9:00 amBogotá El Dorado

27h 32m

2 stops

CMH1:32 pmColumbus

$795

Delta flights from Columbus Airport to South America

Our best Delta deals on Columbus Airport to South America flight tickets

Delta

Jul 14

CMH8:11 amColumbus

12h 59m

2 stops

BOG8:10 pmBogotá El Dorado

Jul 22

BOG11:00 amBogotá El Dorado

12h 44m

2 stops

CMH12:44 amColumbus

$610

Delta

Aug 14

CMH6:00 amColumbus

14h 15m

1 stop

BOG7:15 pmBogotá El Dorado

Aug 23

BOG8:40 amBogotá El Dorado

14h 16m

2 stops

CMH11:56 pmColumbus

$630

Delta

Jun 5

CMH6:00 amColumbus

15h 10m

2 stops

BOG8:10 pmBogotá El Dorado

Jun 8

BOG6:30 pmBogotá El Dorado

16h 21m

2 stops

CMH11:51 amColumbus

$665

momondo Fare Finder

Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sun 5/17

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Thu 5/21

1:31 pm-11:56 pm

1 stop9h 25m

$412

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sun 5/17

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Fri 5/22

1:31 pm-11:56 pm

1 stop9h 25m

$429

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Tue 7/14

10:00 am-7:15 pm

1 stop10h 15m

Bogotá El Dorado

Wed 7/22

2:55 pm-12:44 am

1 stop8h 49m

$605

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Tue 7/14

8:11 am-8:10 pm

2 stops12h 59m

Bogotá El Dorado

Wed 7/22

11:00 am-12:44 am

2 stops12h 44m

$610

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Tue 7/14

5:45 am-10:30 pm

1 stop17h 45m

Bogotá El Dorado

Tue 7/21

6:30 am-10:39 pm

1 stop15h 09m

$617

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Fri 8/14

6:00 am-8:10 pm

2 stops15h 10m

Bogotá El Dorado

Sun 8/23

11:00 am-11:56 pm

2 stops11h 56m

$630

ColumbusQuito

CMH - UIO

CMHUIO

Columbus

Mon 8/10

5:01 pm-5:00 am

1 stop12h 59m

Quito Mariscal Sucr

Sun 8/23

12:35 am-11:02 am

1 stop9h 27m

$696

ColumbusLima

CMH - LIM

CMHLIM

Columbus

Sun 10/4

12:05 pm-6:45 am

1 stop19h 40m

Lima J Chavez Intl

Tue 10/20

12:05 pm-11:55 pm

1 stop10h 50m

$699

ColumbusQuito

CMH - UIO

CMHUIO

Columbus

Mon 8/10

6:30 am-11:25 pm

1 stop17h 55m

Quito Mariscal Sucr

Mon 8/24

7:25 am-8:35 am

2 stops24h 10m

$701

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 6/9

5:08 am-1:31 pm

1 stop9h 23m

Guayaquil Jose Joaquin de Olmedo

Thu 7/30

6:00 am-12:37 am

1 stop17h 37m

$707

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbus Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Columbus Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $225. If you aren’t able to travel during the month of October, then book flights to South America from Columbus Airport during February instead. Flights to South America in February, while not as cheap as those in October, still average around $243.

How far in advance should I book a flight from Columbus Airport to South America?

You are more likely to see cheaper flights to South America from Columbus Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $830 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Columbus Airport for as low as $566 on momondo.

Can stopping save me money on Columbus Airport to South America flights?

You could potentially save up to 61% on your flight if you consider stops on a Columbus Airport to South America flight.

Cheap Columbus Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to South America

Fastest flight time	6h 25m
Direct flights	None

The fastest flight from Columbus Airport to South America takes 6h 25m

There are no direct flights from Columbus Airport to South America. There are no popular flight routes from Columbus Airport to South America.

Search flight deals

Frequently asked questions about flying from Columbus Airport to South America

When did momondo last update prices for flights from Columbus Airport to South America?
Prices for flights from Columbus Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Columbus Airport to South America?
There are 5 operators available for flights from Columbus Airport to South America as of May 2026.
How old do you have to be to fly from Columbus Airport to South America?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Columbus Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus Airport to South America

Compare and see reviews for airlines that fly from Columbus Airport to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $244	Free Cancellation	Rating 6.3 8,636 reviews	Search Spirit Airlines flights
Delta	PriceFrom $552	Free Cancellation	Rating 7.9 8,460 reviews	Search Delta flights
American Airlines	PriceFrom $552	Free Cancellation	Rating 7.1 11,670 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $658	Free Cancellation	Rating 7.4 1,915 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $962	Free Cancellation	Rating 7.4 9,682 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Columbus with this policy.

How can momondo help me find flights from Columbus to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Columbus to South America.

I’m not ready to book a flight from Columbus to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.