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Cheap flights from Columbus Airport to South America from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to South America departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:45 am - 1:15 pm
CMH
-
CTG
7h 30m1 stop
Spirit Airlines Logo
2:21 pm - 11:27 pm
CTG
-
CMH
9h 06m1 stop
$281Spirit Airlines
mié., ene. 21 - mié., ene. 28
Spirit Airlines Logo
5:45 am - 2:07 pm
CMH
-
BOG
8h 22m1 stop
Spirit Airlines Logo
1:45 pm - 11:19 pm
BOG
-
CMH
9h 34m1 stop
$292Spirit Airlines
vie., ene. 23 - mar., ene. 27
LATAM Airlines Logo
7:05 am - 2:33 pm
CMH
-
BOG
8h 28m1 stop
LATAM Airlines Logo
3:55 pm - 10:01 am
BOG
-
CMH
17h 06m1 stop
$481LATAM Airlines
mar., mar. 17 - mar., mar. 24
Delta Logo
1:01 pm - 7:30 pm
CMH
-
BOG
7h 29m1 stop
Delta Logo
6:15 am - 12:31 am
BOG
-
CMH
17h 16m2 stops
$483Delta
mar., mar. 17 - mar., mar. 24
LATAM Airlines Logo
7:05 am - 6:40 pm
CMH
-
BOG
12h 35m2 stops
LATAM Airlines Logo
10:55 am - 12:31 am
BOG
-
CMH
12h 36m2 stops
$488LATAM Airlines
mar., mar. 17 - mar., mar. 24
American Airlines Logo
1:19 pm - 8:15 am
CMH
-
SCL
16h 56m1 stop
American Airlines Logo
10:00 pm - 6:55 pm
SCL
-
CMH
22h 55m1 stop
$764American Airlines
mié., feb. 11 - mié., feb. 25
American Airlines Logo
1:19 pm - 8:15 am
CMH
-
SCL
16h 56m1 stop
American Airlines Logo
10:00 pm - 11:45 am
SCL
-
CMH
15h 45m2 stops
$769American Airlines
mié., feb. 11 - mié., feb. 25
Delta Logo
12:50 pm - 4:50 am
CMH
-
SCL
16h 00m2 stops
Delta Logo
6:45 pm - 1:02 pm
SCL
-
CMH
18h 17m2 stops
$804Delta
mié., may. 13 - mié., may. 20
Air Canada Logo
9:30 am - 3:10 pm
CMH
-
GIG
28h 40m2 stops
Air Canada Logo
8:00 pm - 8:56 pm
GIG
-
CMH
25h 56m1 stop
$940Air Canada
lun., mar. 23 - vie., mar. 27
Air Canada Logo
9:30 am - 10:35 am
CMH
-
GRU
24h 05m1 stop
Air Canada Logo
9:15 pm - 8:56 pm
GRU
-
CMH
48h 41m2 stops
$942Air Canada
mar., mar. 24 - mié., mar. 25

Spirit Airlines flights from Columbus Airport to South America

Our best Spirit Airlines deals on Columbus Airport to South America flight tickets
Spirit Airlines
Jan 21
CMH5:45 amColumbus
7h 30m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Jan 28
CTG2:21 pmCartagena Rafael Nunez
9h 06m
1 stop
CMH11:27 pmColumbus
$281
Find similar
Spirit Airlines
Jan 23
CMH5:45 amColumbus
8h 22m
1 stop
BOG2:07 pmBogotá El Dorado
Jan 27
BOG1:45 pmBogotá El Dorado
9h 34m
1 stop
CMH11:19 pmColumbus
$292
Find similar
Spirit Airlines
Feb 7
CMH5:45 amColumbus
8h 30m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 10
MDE2:50 pmMedellín Jose Maria Cordova Intl
8h 29m
1 stop
CMH11:19 pmColumbus
$294
Find similar

LATAM Airlines flights from Columbus Airport to South America

Our best LATAM Airlines deals on Columbus Airport to South America flight tickets
LATAM Airlines
Mar 17
CMH7:05 amColumbus
8h 28m
1 stop
BOG2:33 pmBogotá El Dorado
Mar 24
BOG3:55 pmBogotá El Dorado
17h 06m
1 stop
CMH10:01 amColumbus
$481
Find similar
LATAM Airlines
Mar 17
CMH7:05 amColumbus
12h 35m
2 stops
BOG6:40 pmBogotá El Dorado
Mar 24
BOG10:55 amBogotá El Dorado
12h 36m
2 stops
CMH12:31 amColumbus
$488
Find similar
LATAM Airlines
Feb 2
CMH7:00 amColumbus
12h 30m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 5
BOG9:00 amBogotá El Dorado
15h 04m
1 stop
CMH12:04 amColumbus
$553
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 11, 2025.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

mié. 1/21

5:45 am-1:15 pm

1 stop7h 30m

Cartagena Rafael Nunez

mié. 1/28

2:21 pm-11:27 pm

1 stop9h 06m

$281

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

vie. 1/23

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

mar. 1/27

1:45 pm-11:19 pm

1 stop9h 34m

$292

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

mar. 3/17

7:05 am-2:33 pm

1 stop8h 28m

Bogotá El Dorado

mar. 3/24

3:55 pm-10:01 am

1 stop17h 06m

$481

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

mar. 3/17

1:01 pm-7:30 pm

1 stop7h 29m

Bogotá El Dorado

mar. 3/24

6:15 am-12:31 am

2 stops17h 16m

$483

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

mar. 3/17

7:05 am-6:40 pm

2 stops12h 35m

Bogotá El Dorado

mar. 3/24

10:55 am-12:31 am

2 stops12h 36m

$488

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mié. 2/11

1:19 pm-8:15 am

1 stop16h 56m

Santiago Arturo Merino Benitez

mié. 2/25

10:00 pm-6:55 pm

1 stop22h 55m

$764

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mié. 2/11

1:19 pm-8:15 am

1 stop16h 56m

Santiago Arturo Merino Benitez

mié. 2/25

10:00 pm-11:45 am

2 stops15h 45m

$769

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mié. 5/13

12:50 pm-4:50 am

2 stops16h 00m

Santiago Arturo Merino Benitez

mié. 5/20

6:45 pm-1:02 pm

2 stops18h 17m

$804

ColumbusRio de Janeiro

CMH - GIG

CMHGIG

Columbus

lun. 3/23

9:30 am-3:10 pm

2 stops28h 40m

Rio de Janeiro–Galeão Intl

vie. 3/27

8:00 pm-8:56 pm

1 stop25h 56m

$940

ColumbusSao Paulo

CMH - GRU

CMHGRU

Columbus

mar. 3/24

9:30 am-10:35 am

1 stop24h 05m

Sao Paulo Guarulhos Intl

mié. 3/25

9:15 pm-8:56 pm

2 stops48h 41m

$942

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbus Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Columbus Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $703. If you aren’t able to travel during the month of February, then book flights to South America from Columbus Airport during January instead. Flights to South America in January, while not as cheap as those in February, still average around $707.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Columbus Airport to South America is on a Wednesday when prices can be found for as low as $776. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Columbus Airport to South America for around $1,087.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Columbus Airport to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $818. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $851 on average. Flights to South America from Columbus Airport in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Columbus Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $820 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Columbus Airport for as low as $684 on momondo.

Can stopping save me money on Columbus Airport to South America flights?

You could potentially save up to 61% on your flight if you consider stops on a Columbus Airport to South America flight.

Cheap Columbus Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to South America

Fastest flight time

6h 58m

Direct flights

None
The fastest flight from Columbus Airport to South America takes 6h 58m
There are no direct flights from Columbus Airport to South America. There are no popular flight routes from Columbus Airport to South America.
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  • When did momondo last update prices for flights from Columbus Airport to South America?

    Prices for flights from Columbus Airport to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus Airport to South America?

  • How old do you have to be to fly from Columbus Airport to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Columbus Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus Airport to South America

Compare and see reviews for airlines that fly from Columbus Airport to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $261Free CancellationRating
6.3
8,175 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $443Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
DeltaPriceFrom $552Free CancellationRating
7.9
8,008 reviews
Search Delta flights
LATAM AirlinesPriceFrom $555Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
Air CanadaPriceFrom $744Free CancellationRating
7.1
10,514 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Columbus with this policy.

How can momondo help me find flights from Columbus to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Columbus to South America.

I’m not ready to book a flight from Columbus to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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sáb. 1/10
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Find better results for your trip to South America

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