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Cheap flights from Houston George Bush Intcntl Airport to Knoxville from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston George Bush Intcntl Airport to Knoxville departing on 4/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Houston George Bush Intcntl Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:15 pm - 10:59 pm
IAH
-
TYS
24h 44m
1 stop
Multiple Airlines Logo
8:30 am - 8:38 am
TYS
-
IAH
25h 08m
1 stop
$174Multiple Airlines
mié., mar. 25 - mié., abr. 1
Multiple Airlines Logo
9:03 pm - 9:34 pm
IAH
-
TYS
23h 31m
1 stop
Multiple Airlines Logo
8:30 am - 8:38 am
TYS
-
IAH
25h 08m
1 stop
$177Multiple Airlines
vie., mar. 27 - mié., abr. 1
Multiple Airlines Logo
9:03 pm - 11:12 am
IAH
-
TYS
13h 09m
1 stop
Multiple Airlines Logo
8:30 am - 8:38 am
TYS
-
IAH
25h 08m
1 stop
$179Multiple Airlines
lun., mar. 23 - mié., abr. 1
Multiple Airlines Logo
9:15 pm - 10:59 pm
IAH
-
TYS
24h 44m
1 stop
Multiple Airlines Logo
2:06 pm - 8:20 pm
TYS
-
IAH
7h 14m
1 stop
$182Multiple Airlines
mié., mar. 25 - vie., abr. 3
Multiple Airlines Logo
9:03 pm - 9:34 pm
IAH
-
TYS
23h 31m
1 stop
Multiple Airlines Logo
2:06 pm - 8:20 pm
TYS
-
IAH
7h 14m
1 stop
$185Multiple Airlines
vie., mar. 27 - vie., abr. 3
Multiple Airlines Logo
9:03 pm - 11:12 am
IAH
-
TYS
13h 09m
1 stop
Multiple Airlines Logo
2:06 pm - 8:20 pm
TYS
-
IAH
7h 14m
1 stop
$187Multiple Airlines
lun., mar. 23 - vie., abr. 3
Multiple Airlines Logo
9:15 pm - 10:59 pm
IAH
-
TYS
24h 44m
1 stop
Multiple Airlines Logo
9:46 pm - 7:02 am
TYS
-
IAH
10h 16m
1 stop
$188Multiple Airlines
mié., mar. 25 - jue., abr. 2
Multiple Airlines Logo
9:03 pm - 11:12 am
IAH
-
TYS
13h 09m
1 stop
Multiple Airlines Logo
9:46 pm - 7:02 am
TYS
-
IAH
10h 16m
1 stop
$193Multiple Airlines
lun., mar. 23 - jue., abr. 2
Multiple Airlines Logo
9:15 pm - 12:51 pm
IAH
-
TYS
14h 36m
1 stop
Multiple Airlines Logo
2:06 pm - 8:20 pm
TYS
-
IAH
7h 14m
1 stop
$195Multiple Airlines
mar., mar. 24 - vie., abr. 3
Multiple Airlines Logo
9:03 pm - 11:12 am
IAH
-
TYS
13h 09m
1 stop
Multiple Airlines Logo
12:02 pm - 8:20 pm
TYS
-
IAH
9h 18m
1 stop
$198Multiple Airlines
lun., mar. 23 - mar., mar. 31

American Airlines flights from Houston George Bush Intcntl Airport to Knoxville

Our best American Airlines deals on Houston George Bush Intcntl Airport to Knoxville flight tickets
American Airlines
Apr 29
IAH6:00 amHouston George Bush Intcntl
5h 30m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
May 2
TYS6:54 pmKnoxville McGhee Tyson
4h 35m
1 stop
IAH10:29 pmHouston George Bush Intcntl
$229
American Airlines
Mar 18
IAH6:28 amHouston George Bush Intcntl
8h 04m
1 stop
TYS3:32 pmKnoxville McGhee Tyson
Mar 25
TYS5:00 amKnoxville McGhee Tyson
7h 16m
1 stop
IAH11:16 amHouston George Bush Intcntl
$249
American Airlines
Mar 11
IAH5:00 amHouston George Bush Intcntl
5h 30m
1 stop
TYS11:30 amKnoxville McGhee Tyson
Mar 18
TYS5:02 pmKnoxville McGhee Tyson
6h 46m
1 stop
IAH10:48 pmHouston George Bush Intcntl
$324

Delta flights from Houston George Bush Intcntl Airport to Knoxville

Our best Delta deals on Houston George Bush Intcntl Airport to Knoxville flight tickets
Delta
Apr 3
IAH6:54 pmHouston George Bush Intcntl
4h 03m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
Apr 6
TYS5:40 amKnoxville McGhee Tyson
4h 16m
1 stop
IAH8:56 amHouston George Bush Intcntl
$254
Delta
Mar 7
IAH7:05 amHouston George Bush Intcntl
5h 49m
1 stop
TYS1:54 pmKnoxville McGhee Tyson
Mar 10
TYS10:04 amKnoxville McGhee Tyson
6h 47m
1 stop
IAH3:51 pmHouston George Bush Intcntl
$419
Delta
Mar 12
IAH5:23 amHouston George Bush Intcntl
4h 54m
1 stop
TYS11:17 amKnoxville McGhee Tyson
Mar 24
TYS5:40 amKnoxville McGhee Tyson
5h 50m
1 stop
IAH10:30 amHouston George Bush Intcntl
$424

momondo Fare Finder

 
Customize your flight search to find flights from Houston George Bush Intcntl Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated marzo 4, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

mié. 3/25

9:15 pm-10:59 pm

1 stop24h 44m

Knoxville McGhee Tyson

mié. 4/1

8:30 am-8:38 am

1 stop25h 08m

$174

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

vie. 3/27

9:03 pm-9:34 pm

1 stop23h 31m

Knoxville McGhee Tyson

mié. 4/1

8:30 am-8:38 am

1 stop25h 08m

$177

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

lun. 3/23

9:03 pm-11:12 am

1 stop13h 09m

Knoxville McGhee Tyson

mié. 4/1

8:30 am-8:38 am

1 stop25h 08m

$179

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

mié. 3/25

9:15 pm-10:59 pm

1 stop24h 44m

Knoxville McGhee Tyson

vie. 4/3

2:06 pm-8:20 pm

1 stop7h 14m

$182

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

vie. 3/27

9:03 pm-9:34 pm

1 stop23h 31m

Knoxville McGhee Tyson

vie. 4/3

2:06 pm-8:20 pm

1 stop7h 14m

$185

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

lun. 3/23

9:03 pm-11:12 am

1 stop13h 09m

Knoxville McGhee Tyson

vie. 4/3

2:06 pm-8:20 pm

1 stop7h 14m

$187

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

mié. 3/25

9:15 pm-10:59 pm

1 stop24h 44m

Knoxville McGhee Tyson

jue. 4/2

9:46 pm-7:02 am

1 stop10h 16m

$188

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

lun. 3/23

9:03 pm-11:12 am

1 stop13h 09m

Knoxville McGhee Tyson

jue. 4/2

9:46 pm-7:02 am

1 stop10h 16m

$193

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

mar. 3/24

9:15 pm-12:51 pm

1 stop14h 36m

Knoxville McGhee Tyson

vie. 4/3

2:06 pm-8:20 pm

1 stop7h 14m

$195

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

lun. 3/23

9:03 pm-11:12 am

1 stop13h 09m

Knoxville McGhee Tyson

mar. 3/31

12:02 pm-8:20 pm

1 stop9h 18m

$198

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Houston George Bush Intcntl Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of October is, on average, the cheapest month to fly to Knoxville from Houston George Bush Intcntl Airport, with most prices found around $288. If you aren’t able to travel during the month of October, then book flights to Knoxville from Houston George Bush Intcntl Airport during April instead. Flights to Knoxville in April, while not as cheap as those in October, still average around $298.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Houston George Bush Intcntl Airport to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $88. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Houston George Bush Intcntl Airport to Knoxville for around $399.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Houston George Bush Intcntl Airport to Knoxville when you can find flight prices for as low as $248. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $402.

What is the cheapest Houston George Bush Intcntl to Knoxville McGhee Tyson flight route?

Fly from Houston George Bush Intcntl to Knoxville McGhee Tyson for the best Houston George Bush Intcntl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Houston George Bush Intcntl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Houston George Bush Intcntl Airport for as low as $328 on momondo.

What cabin class options are available on Houston George Bush Intcntl to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Houston George Bush Intcntl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Houston George Bush Intcntl Airport to Knoxville flights?

You could potentially save up to 9% on your flight if you consider stops on a Houston George Bush Intcntl Airport to Knoxville flight.

How have Houston George Bush Intcntl Airport to Knoxville flight prices changed over time?

As of March 2026, prices for Houston George Bush Intcntl Airport to Knoxville flights are approximately 3% cheaper when compared to flights at the same time last year.

When to book flights from Houston George Bush Intcntl Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Houston George Bush Intcntl Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Houston George Bush Intcntl Airport to Knoxville (IAH to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston George Bush Intcntl Airport to Knoxville

Best Price Found

$258

Fastest flight time

2h 14m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Houston George Bush Intcntl Airport in the past 72 hours is $258. The best round-trip flight deal from Houston George Bush Intcntl Airport to Knoxville found on momondo in the last 72 hours is $329.
The fastest flight from Houston George Bush Intcntl Airport to Knoxville takes 2h 14m
Direct flights go from Houston George Bush Intcntl Airport to Knoxville every day.
There is 1 airport in Knoxville. From Houston George Bush Intcntl Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Houston George Bush Intcntl to Knoxville McGhee Tyson by plane?

    A flight from Houston George Bush Intcntl to Knoxville McGhee Tyson will travel around 778.8 mi. By plane, this route typically takes 2h 14m.

  • When did momondo last update prices for flights from Houston George Bush Intcntl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Houston George Bush Intcntl Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Houston George Bush Intcntl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Houston George Bush Intcntl Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston George Bush Intcntl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Houston George Bush Intcntl Airport to Knoxville?

  • What is the most popular airline from Houston George Bush Intcntl Airport to Knoxville?

Best airlines flying from Houston George Bush Intcntl Airport to Knoxville

Compare and see reviews for airlines that fly from Houston George Bush Intcntl Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $104Free CancellationRating
7.9
8,245 reviews
Search Delta flights
United AirlinesPriceFrom $209Free CancellationRating
7.4
9,382 reviews
Search United Airlines flights
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,378 reviews
Search American Airlines flights

  • United Airlines Flights From Houston George Bush Intcntl Airport to Knoxville

    United Airlines flies from Houston George Bush Intcntl Airport to Knoxville around 22 times per week, with 9,382 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Houston George Bush Intcntl Airport to Knoxville in the last 72 hours was $209 (round-trip), much lower than the average airfare cost of $406 for United Airlines flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Kodak
Newport
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Knoxville?

Finding the right flight to Knoxville from Houston is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Houston to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Knoxville?

Once all potential Houston to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Houston to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Houston and alert you when they change.

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vie. 4/3
vie. 4/10
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