What is the cheapest airline that flies from Fort Myers SW Florida Intl to South America?

American Airlines and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to South America

What airlines fly to South America?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to South America from Fort Myers according to our data. Delta is the first choice among our users, with 74% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to South America?

Prices for flights from Fort Myers SW Florida Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to South America?

There are 2 operators available for flights from Fort Myers SW Florida Intl Airport to South America as of September 2025.

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$323 Cheap Flights from Fort Myers to South America in 2025/26

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Find the cheapest flights from Fort Myers to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

7:11 pm - 6:04 pmRSW-MDE

22h 53m3 stops

2:23 pm - 11:00 amMDE-RSW

20h 37m2 stops

$500Multiple Airlines

Find Deal

Tue, Nov 11 - Tue, Dec 2

7:00 am - 12:28 amRSW-MDE

18h 28m2 stops

1:16 am - 8:41 pmMDE-RSW

18h 25m2 stops

$516Spirit Airlines

Find Deal

Fri, Oct 3 - Sat, Oct 18

7:00 am - 11:07 pmRSW-MDE

41h 07m3 stops

1:16 am - 8:41 pmMDE-RSW

18h 25m2 stops

$522Multiple Airlines

Find Deal

Fri, Oct 3 - Sat, Oct 18

7:51 pm - 1:35 pmRSW-MDE

17h 44m2 stops

6:50 am - 12:21 amMDE-RSW

17h 31m2 stops

$551American Airlines

Find Deal

Sat, Feb 21 - Sat, Feb 28

10:30 am - 8:55 pmRSW-MDE

10h 25m2 stops

4:10 pm - 10:46 amMDE-RSW

18h 36m2 stops

$555American Airlines

Find Deal

Tue, Feb 24 - Mon, Mar 2

7:00 am - 10:05 pmRSW-MDE

15h 05m1 stop

10:45 am - 2:46 pmMDE-RSW

28h 01m2 stops

$567United Airlines

Find Deal

Tue, Nov 11 - Tue, Dec 2

3:40 pm - 2:05 pmRSW-MDE

23h 25m2 stops

1:30 pm - 10:43 amMDE-RSW

20h 13m2 stops

$595JetBlue

Find Deal

Tue, Oct 14 - Fri, Oct 17

6:40 pm - 9:05 pmRSW-MDE

27h 25m2 stops

10:45 am - 11:27 amMDE-RSW

24h 42m2 stops

$617United Airlines

Find Deal

Fri, Oct 31 - Fri, Nov 7

5:38 pm - 5:20 amRSW-IQT

35h 42m2 stops

8:10 am - 9:44 amIQT-RSW

25h 34m2 stops

$764Delta

Find Deal

Sun, Dec 7 - Wed, Dec 10

5:38 pm - 1:35 pmRSW-IQT

19h 57m2 stops

12:05 am - 4:32 pmIQT-RSW

40h 27m2 stops

$776Delta

Find Deal

Sun, Dec 7 - Tue, Dec 9

American Airlines flights from Fort Myers to South America

Our best American Airlines deals on Fort Myers to South America flight tickets

American Airlines

Feb 21

RSW7:51 pmFort Myers SW Florida Intl

17h 44m

2 stops

MDE1:35 pmMedellín Jose Maria Cordova Intl

Feb 28

MDE6:50 amMedellín Jose Maria Cordova Intl

17h 31m

2 stops

RSW12:21 amFort Myers SW Florida Intl

$551

Find similar

American Airlines

Feb 24

RSW10:30 amFort Myers SW Florida Intl

10h 25m

2 stops

MDE8:55 pmMedellín Jose Maria Cordova Intl

Mar 2

MDE4:10 pmMedellín Jose Maria Cordova Intl

18h 36m

2 stops

RSW10:46 amFort Myers SW Florida Intl

$555

Find similar

American Airlines

Nov 11

RSW6:33 pmFort Myers SW Florida Intl

19h 36m

2 stops

MDE2:09 pmMedellín Jose Maria Cordova Intl

Dec 1

MDE1:30 amMedellín Jose Maria Cordova Intl

15h 24m

2 stops

RSW4:54 pmFort Myers SW Florida Intl

$566

Find similar

United Airlines flights from Fort Myers to South America

Our best United Airlines deals on Fort Myers to South America flight tickets

United Airlines

Nov 11

RSW7:00 amFort Myers SW Florida Intl

15h 05m

1 stop

MDE10:05 pmMedellín Jose Maria Cordova Intl

Dec 2

MDE10:45 amMedellín Jose Maria Cordova Intl

28h 01m

2 stops

RSW2:46 pmFort Myers SW Florida Intl

$567

Find similar

United Airlines

Oct 31

RSW6:40 pmFort Myers SW Florida Intl

27h 25m

2 stops

MDE9:05 pmMedellín Jose Maria Cordova Intl

Nov 7

MDE10:45 amMedellín Jose Maria Cordova Intl

24h 42m

2 stops

RSW11:27 amFort Myers SW Florida Intl

$617

Find similar

United Airlines

Nov 1

RSW5:08 pmFort Myers SW Florida Intl

29h 57m

1 stop

MDE10:05 pmMedellín Jose Maria Cordova Intl

Nov 8

MDE10:45 amMedellín Jose Maria Cordova Intl

11h 06m

1 stop

RSW9:51 pmFort Myers SW Florida Intl

$623

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Fort Myers to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Tue 11/11

7:11 pm-6:04 pm

3 stops22h 53m

Medellín Jose Maria Cordova Intl

Tue 12/2

2:23 pm-11:00 am

2 stops20h 37m

$500

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Fri 10/3

7:00 am-12:28 am

2 stops18h 28m

Medellín Jose Maria Cordova Intl

Sat 10/18

1:16 am-8:41 pm

2 stops18h 25m

$516

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Fri 10/3

7:00 am-11:07 pm

3 stops41h 07m

Medellín Jose Maria Cordova Intl

Sat 10/18

1:16 am-8:41 pm

2 stops18h 25m

$522

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Sat 2/21

7:51 pm-1:35 pm

2 stops17h 44m

Medellín Jose Maria Cordova Intl

Sat 2/28

6:50 am-12:21 am

2 stops17h 31m

$551

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Tue 2/24

10:30 am-8:55 pm

2 stops10h 25m

Medellín Jose Maria Cordova Intl

Mon 3/2

4:10 pm-10:46 am

2 stops18h 36m

$555

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Tue 11/11

7:00 am-10:05 pm

1 stop15h 05m

Medellín Jose Maria Cordova Intl

Tue 12/2

10:45 am-2:46 pm

2 stops28h 01m

$567

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Tue 10/14

3:40 pm-2:05 pm

2 stops23h 25m

Medellín Jose Maria Cordova Intl

Fri 10/17

1:30 pm-10:43 am

2 stops20h 13m

$595

Fort MyersMedellín

RSW - MDE

RSWMDE

Fort Myers SW Florida Intl

Fri 10/31

6:40 pm-9:05 pm

2 stops27h 25m

Medellín Jose Maria Cordova Intl

Fri 11/7

10:45 am-11:27 am

2 stops24h 42m

$617

Fort MyersIquitos

RSW - IQT

RSWIQT

Fort Myers SW Florida Intl

Sun 12/7

5:38 pm-5:20 am

2 stops35h 42m

Iquitos C.F. Secada

Wed 12/10

8:10 am-9:44 am

2 stops25h 34m

$764

Fort MyersIquitos

RSW - IQT

RSWIQT

Fort Myers SW Florida Intl

Sun 12/7

5:38 pm-1:35 pm

2 stops19h 57m

Iquitos C.F. Secada

Tue 12/9

12:05 am-4:32 pm

2 stops40h 27m

$776

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Fort Myers to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Fort Myers to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $594. If you aren’t able to travel during the month of September, then book flights to South America from Fort Myers during January instead. Flights to South America in January, while not as cheap as those in September, still average around $615.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Fort Myers to South America is on a Monday when prices can be found for as low as $583. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Fort Myers to South America for around $793.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Fort Myers to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $576. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $723 on average. Flights to South America from Fort Myers in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Fort Myers to South America flights?

You could potentially save up to 43% on your flight if you consider stops on a Fort Myers to South America flight.

Cheap Fort Myers to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to South America

Direct flights	None

There are no direct flights from Fort Myers to South America. There are no popular flight routes from Fort Myers to South America.

Search flight deals

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to South America?
Prices for flights from Fort Myers SW Florida Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to South America?
There are 2 operators available for flights from Fort Myers SW Florida Intl Airport to South America as of September 2025.
How old do you have to be to fly from Fort Myers SW Florida Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Fort Myers to South America

Compare and see reviews for airlines that fly from Fort Myers to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $434	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
Delta	PriceFrom $450	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights
American Airlines	PriceFrom $772	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Fort Myers to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Fort Myers to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Fort Myers to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Fort Myers to South America?

momondo provides multiple filters to help you find the best flight to South America from Fort Myers. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Fort Myers to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Fort Myers are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $327

Flights to Buenos Airesfrom $552

Flights to Bogotáfrom $180

Flights to Sao Paulofrom $351

Flights to Medellínfrom $165

Flights to Rio de Janeirofrom $404

Flights to Santiagofrom $395

Flights to Cartagenafrom $181

Flights to Quitofrom $277

Flights to Cuscofrom $361

Flights to Califrom $195

Flights to Guayaquilfrom $242

Cheap flights from Fort Myers to South America from $323

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to South America departing on 12/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Fort Myers to South America

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

American Airlines flights from Fort Myers to South America

Our best American Airlines deals on Fort Myers to South America flight tickets

United Airlines flights from Fort Myers to South America

Our best United Airlines deals on Fort Myers to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Fort Myers to South America that are best for you.

How to get the cheapest flight ticket from Fort Myers to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Fort Myers to South America is on a Monday when prices can be found for as low as $583. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Fort Myers to South America for around $793.

What is the cheapest time of day to depart on your flight to South America?

Can stopping save me money on Fort Myers to South America flights?

You could potentially save up to 43% on your flight if you consider stops on a Fort Myers to South America flight.

What is the cheapest airline that flies from Fort Myers SW Florida Intl to South America?

American Airlines and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to South America

What airlines fly to South America?

Cheap Fort Myers to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to South America

Direct flights

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to South America?

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to South America?

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Fort Myers to South America

Compare and see reviews for airlines that fly from Fort Myers to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to South America?

Can I find flights from Fort Myers to South America with flexible booking policies on momondo?

How can momondo help me find flights from Fort Myers to South America?

I’m not ready to book a flight from Fort Myers to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo