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Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Fe from $274

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santa Fe departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:51 pm - 8:32 pm
DTW
-
SAF
8h 41m
1 stop
American Airlines Logo
6:45 am - 2:04 pm
SAF
-
DTW
5h 19m
1 stop
$344American Airlines
Wed, Sep 23 - Sat, Sep 26
American Airlines Logo
5:36 am - 9:41 am
DTW
-
SAF
6h 05m
1 stop
American Airlines Logo
7:21 am - 2:56 pm
SAF
-
DTW
5h 35m
1 stop
$345American Airlines
Tue, Aug 4 - Wed, Aug 12
American Airlines Logo
7:44 am - 3:05 pm
DTW
-
SAF
9h 21m
2 stops
American Airlines Logo
7:21 am - 2:56 pm
SAF
-
DTW
5h 35m
1 stop
$354American Airlines
Sat, Aug 22 - Wed, Aug 26
United Airlines Logo
8:00 am - 12:47 pm
DTW
-
SAF
6h 47m
1 stop
United Airlines Logo
1:22 pm - 10:43 pm
SAF
-
DTW
7h 21m
1 stop
$361United Airlines
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
6:09 am - 12:06 pm
DTW
-
SAF
7h 57m
1 stop
American Airlines Logo
12:36 pm - 10:59 pm
SAF
-
DTW
8h 23m
1 stop
$369American Airlines
Wed, May 6 - Wed, May 13
American Airlines Logo
4:10 pm - 9:52 pm
DTW
-
SAF
7h 42m
1 stop
American Airlines Logo
7:30 am - 3:14 pm
SAF
-
DTW
5h 44m
1 stop
$374American Airlines
Fri, May 29 - Wed, Jun 3
United Airlines Logo
9:19 am - 5:13 pm
DTW
-
SAF
9h 54m
2 stops
United Airlines Logo
3:31 pm - 10:53 pm
SAF
-
DTW
5h 22m
1 stop
$375United Airlines
Wed, May 6 - Wed, May 13
American Airlines Logo
7:44 am - 3:05 pm
DTW
-
SAF
9h 21m
2 stops
American Airlines Logo
7:21 am - 2:56 pm
SAF
-
DTW
5h 35m
1 stop
$384American Airlines
Sat, Aug 15 - Wed, Aug 19
United Airlines Logo
7:28 am - 2:44 pm
DTW
-
SAF
9h 16m
2 stops
United Airlines Logo
1:22 pm - 10:43 pm
SAF
-
DTW
7h 21m
1 stop
$409United Airlines
Tue, Jun 30 - Tue, Jul 7
United Airlines Logo
9:00 am - 5:13 pm
DTW
-
SAF
10h 13m
2 stops
United Airlines Logo
3:31 pm - 10:53 pm
SAF
-
DTW
5h 22m
1 stop
$420United Airlines
Fri, May 8 - Wed, May 13

American Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Fe

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Fe flight tickets
American Airlines
Sep 23
DTW1:51 pmDetroit Metropolitan Wayne County
8h 41m
1 stop
SAF8:32 pmSanta Fe
Sep 26
SAF6:45 amSanta Fe
5h 19m
1 stop
DTW2:04 pmDetroit Metropolitan Wayne County
$344
American Airlines
Aug 4
DTW5:36 amDetroit Metropolitan Wayne County
6h 05m
1 stop
SAF9:41 amSanta Fe
Aug 12
SAF7:21 amSanta Fe
5h 35m
1 stop
DTW2:56 pmDetroit Metropolitan Wayne County
$345
American Airlines
Aug 22
DTW7:44 amDetroit Metropolitan Wayne County
9h 21m
2 stops
SAF3:05 pmSanta Fe
Aug 26
SAF7:21 amSanta Fe
5h 35m
1 stop
DTW2:56 pmDetroit Metropolitan Wayne County
$354

United Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Fe

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Fe flight tickets
United Airlines
Jun 30
DTW8:00 amDetroit Metropolitan Wayne County
6h 47m
1 stop
SAF12:47 pmSanta Fe
Jul 7
SAF1:22 pmSanta Fe
7h 21m
1 stop
DTW10:43 pmDetroit Metropolitan Wayne County
$361
United Airlines
May 6
DTW9:19 amDetroit Metropolitan Wayne County
9h 54m
2 stops
SAF5:13 pmSanta Fe
May 13
SAF3:31 pmSanta Fe
5h 22m
1 stop
DTW10:53 pmDetroit Metropolitan Wayne County
$375
United Airlines
Jun 30
DTW7:28 amDetroit Metropolitan Wayne County
9h 16m
2 stops
SAF2:44 pmSanta Fe
Jul 7
SAF1:22 pmSanta Fe
7h 21m
1 stop
DTW10:43 pmDetroit Metropolitan Wayne County
$409

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 9/23

1:51 pm-8:32 pm

1 stop8h 41m

Santa Fe

Sat 9/26

6:45 am-2:04 pm

1 stop5h 19m

$344
Quickest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 8/4

5:36 am-9:41 am

1 stop6h 05m

Santa Fe

Wed 8/12

7:21 am-2:56 pm

1 stop5h 35m

$345

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 8/22

7:44 am-3:05 pm

2 stops9h 21m

Santa Fe

Wed 8/26

7:21 am-2:56 pm

1 stop5h 35m

$354

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 6/30

8:00 am-12:47 pm

1 stop6h 47m

Santa Fe

Tue 7/7

1:22 pm-10:43 pm

1 stop7h 21m

$361

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 5/6

6:09 am-12:06 pm

1 stop7h 57m

Santa Fe

Wed 5/13

12:36 pm-10:59 pm

1 stop8h 23m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 5/29

4:10 pm-9:52 pm

1 stop7h 42m

Santa Fe

Wed 6/3

7:30 am-3:14 pm

1 stop5h 44m

$374

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 5/6

9:19 am-5:13 pm

2 stops9h 54m

Santa Fe

Wed 5/13

3:31 pm-10:53 pm

1 stop5h 22m

$375

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 8/15

7:44 am-3:05 pm

2 stops9h 21m

Santa Fe

Wed 8/19

7:21 am-2:56 pm

1 stop5h 35m

$384

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 6/30

7:28 am-2:44 pm

2 stops9h 16m

Santa Fe

Tue 7/7

1:22 pm-10:43 pm

1 stop7h 21m

$409

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 5/8

9:00 am-5:13 pm

2 stops10h 13m

Santa Fe

Wed 5/13

3:31 pm-10:53 pm

1 stop5h 22m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Santa Fe?

What is the cheapest month to fly to Santa Fe?

The month of November is, on average, the cheapest month to fly to Santa Fe from Detroit Metropolitan Wayne County Airport, with most prices found around $408. If you’re not able to fly to Santa Fe in November, then May is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Santa Fe during May average around $439.

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Fe (DTW to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Fe

Fastest flight time

5h 31m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Santa Fe takes 5h 31m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santa Fe. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santa Fe.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Santa Fe

  • How far is Detroit Metropolitan Wayne County to Santa Fe by plane?

    Detroit Metropolitan Wayne County and Santa Fe are 1289.2 mi apart from one another. 5h 31m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Fe Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Fe Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Santa Fe Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Fe Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Santa Fe?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Santa Fe

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $284Free CancellationRating
7.1
11,645 reviews
Search American Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
9,613 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Detroit to Santa Fe. momondo saves you time and could save you money on your trip.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

momondo helps you find the best flight between Detroit and Santa Fe by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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