Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Knoxville departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville

Cheap round-trip flights

Logo
7:10 am - 8:31 pmDTW-TYS
13h 21m1 stop
Logo
7:15 am - 6:55 pmTYS-DTW
11h 40m1 stop
$205
Find Deal
Sun, Sep 28 - Wed, Oct 1
Logo
7:02 am - 5:34 pmDTW-TYS
10h 32m1 stop
Logo
1:22 pm - 10:40 pmTYS-DTW
9h 18m1 stop
$208
Find Deal
Mon, Sep 8 - Fri, Sep 12
Logo
7:10 am - 8:35 pmDTW-TYS
13h 25m1 stop
Logo
4:26 pm - 11:29 pmTYS-DTW
7h 03m1 stop
$218
Find Deal
Sun, Oct 12 - Sat, Oct 18
Logo
7:02 am - 5:34 pmDTW-TYS
10h 32m1 stop
Logo
1:22 pm - 8:14 amTYS-DTW
18h 52m2 stops
$223
Find Deal
Mon, Sep 8 - Fri, Sep 12
Logo
2:28 pm - 9:17 pmDTW-TYS
6h 49m1 stop
Logo
5:44 pm - 8:41 amTYS-DTW
14h 57m2 stops
$228
Find Deal
Thu, Oct 2 - Sun, Oct 5
Logo
6:15 am - 11:54 amDTW-TYS
5h 39m1 stop
Logo
4:31 pm - 11:40 pmTYS-DTW
7h 09m1 stop
$229
Find Deal
Wed, Aug 27 - Wed, Sep 3
Frontier Logo
11:54 am - 7:50 pmDTW-TYS
7h 56m1 stop
Frontier Logo
5:08 pm - 12:46 amTYS-DTW
7h 38m1 stop
$239Frontier
Find Deal
Thu, Oct 2 - Sun, Oct 5
Frontier Logo
11:54 am - 7:41 pmDTW-TYS
7h 47m1 stop
Frontier Logo
7:10 pm - 9:43 pmTYS-DTW
26h 33m1 stop
$245Frontier
Find Deal
Thu, Aug 21 - Mon, Aug 25
Frontier Logo
6:10 am - 7:50 pmDTW-TYS
13h 40m1 stop
Frontier Logo
5:08 pm - 12:46 amTYS-DTW
7h 38m1 stop
$268Frontier
Find Deal
Thu, Sep 11 - Sun, Sep 14
American Airlines Logo
6:55 am - 2:34 pmDTW-TYS
7h 39m1 stop
American Airlines Logo
12:56 pm - 9:55 pmTYS-DTW
8h 59m1 stop
$269American Airlines
Find Deal
Sat, Aug 23 - Sat, Aug 30

Frontier flights from Detroit Metropolitan Wayne County Airport to Knoxville

Our best Frontier deals on Detroit Metropolitan Wayne County Airport to Knoxville flight tickets
Frontier
Oct 2
DTW11:54 amDetroit Metropolitan Wayne County
7h 56m
1 stop
TYS7:50 pmKnoxville McGhee Tyson
Oct 5
TYS5:08 pmKnoxville McGhee Tyson
7h 38m
1 stop
DTW12:46 amDetroit Metropolitan Wayne County
$239
Find similar
Frontier
Aug 21
DTW11:54 amDetroit Metropolitan Wayne County
7h 47m
1 stop
TYS7:41 pmKnoxville McGhee Tyson
Aug 25
TYS7:10 pmKnoxville McGhee Tyson
26h 33m
1 stop
DTW9:43 pmDetroit Metropolitan Wayne County
$245
Find similar
Frontier
Aug 7
DTW6:00 amDetroit Metropolitan Wayne County
10h 29m
1 stop
TYS4:29 pmKnoxville McGhee Tyson
Aug 10
TYS5:25 pmKnoxville McGhee Tyson
7h 17m
1 stop
DTW12:42 amDetroit Metropolitan Wayne County
$268
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sun 9/28

7:10 am-8:31 pm

1 stop13h 21m

Knoxville McGhee Tyson

Wed 10/1

7:15 am-6:55 pm

1 stop11h 40m

$205

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/8

7:02 am-5:34 pm

1 stop10h 32m

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-10:40 pm

1 stop9h 18m

$208

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sun 10/12

7:10 am-8:35 pm

1 stop13h 25m

Knoxville McGhee Tyson

Sat 10/18

4:26 pm-11:29 pm

1 stop7h 03m

$218

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/8

7:02 am-5:34 pm

1 stop10h 32m

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-8:14 am

2 stops18h 52m

$223

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 10/2

2:28 pm-9:17 pm

1 stop6h 49m

Knoxville McGhee Tyson

Sun 10/5

5:44 pm-8:41 am

2 stops14h 57m

$228

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 8/27

6:15 am-11:54 am

1 stop5h 39m

Knoxville McGhee Tyson

Wed 9/3

4:31 pm-11:40 pm

1 stop7h 09m

$229

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 10/2

11:54 am-7:50 pm

1 stop7h 56m

Knoxville McGhee Tyson

Sun 10/5

5:08 pm-12:46 am

1 stop7h 38m

$239

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 8/21

11:54 am-7:41 pm

1 stop7h 47m

Knoxville McGhee Tyson

Mon 8/25

7:10 pm-9:43 pm

1 stop26h 33m

$245

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/11

6:10 am-7:50 pm

1 stop13h 40m

Knoxville McGhee Tyson

Sun 9/14

5:08 pm-12:46 am

1 stop7h 38m

$268

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 8/23

6:55 am-2:34 pm

1 stop7h 39m

Knoxville McGhee Tyson

Sat 8/30

12:56 pm-9:55 pm

1 stop8h 59m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Detroit Metropolitan Wayne County Airport, with most prices found around $371. If you aren’t able to travel during the month of December, then book flights to Knoxville from Detroit Metropolitan Wayne County Airport during January instead. Flights to Knoxville in January, while not as cheap as those in December, still average around $374.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $399. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Detroit Metropolitan Wayne County Airport to Knoxville for around $497.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Detroit Metropolitan Wayne County Airport to Knoxville when you can find flight prices for as low as $422. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $478.

What is the cheapest Detroit Metropolitan Wayne County to Knoxville McGhee Tyson flight route?

Fly from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson for the best Detroit Metropolitan Wayne County - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $435 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Detroit Metropolitan Wayne County Airport for as low as $354 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Detroit Metropolitan Wayne County to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Knoxville flights?

You could potentially save up to 74% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Knoxville flight.

How have Detroit Metropolitan Wayne County Airport to Knoxville flight prices changed over time?

When to book flights from Detroit Metropolitan Wayne County Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Knoxville (DTW to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Knoxville

Best Price Found

$95

Fastest flight time

5h 02m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Detroit Metropolitan Wayne County Airport in the past 72 hours is $95. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to Knoxville found on momondo in the last 72 hours is $205.
The fastest flight from Detroit Metropolitan Wayne County Airport to Knoxville takes 5h 02m
Direct flights go from Detroit Metropolitan Wayne County Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Knoxville McGhee Tyson by plane?

    There are 433.4 mi between Detroit Metropolitan Wayne County and Knoxville McGhee Tyson. Flights usually cover this in 5h 02m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Knoxville?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Knoxville?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Knoxville

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $259Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $309Free CancellationRating
8.0
7,981 reviews
Search Delta flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to Knoxville

    Delta flies from Detroit Metropolitan Wayne County Airport to Knoxville around 18 times per week, with 7,981 momondo users rating the airline 8.0/10. The cheapest Delta deal from Detroit Metropolitan Wayne County Airport to Knoxville in the last 72 hours was $309 (round-trip), much lower than the average airfare cost of $455 for Delta flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Detroit.

Can I find flights from Detroit to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to Knoxville?

Once all potential Detroit to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/5
Tue 8/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States