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Cheap flights from Des Moines to Tuscany from $435

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Tuscany departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Tuscany

Cheap round-trip flights

Enter your travel dates to find the best prices.
Air Canada Logo
8:00 am - 9:25 amDSM-FCO
18h 25m2 stops
Air Canada Logo
1:10 pm - 10:53 amFCO-DSM
28h 43m2 stops
$471Air Canada
Find Deal
vie., dic. 5 - vie., dic. 12
Multiple Airlines Logo
5:34 am - 7:55 amDSM-FCO
19h 21m1 stop
Multiple Airlines Logo
10:05 am - 10:34 pmFCO-DSM
19h 29m1 stop
$506Multiple Airlines
Find Deal
vie., dic. 5 - vie., dic. 12
Lufthansa Logo
6:50 pm - 6:30 pmDSM-FLR
16h 40m2 stops
Lufthansa Logo
1:15 pm - 9:37 pmFLR-DSM
15h 22m2 stops
$509Lufthansa
Find Deal
vie., dic. 5 - vie., dic. 12
Lufthansa Logo
6:50 pm - 5:50 pmDSM-FCO
16h 00m2 stops
Lufthansa Logo
12:20 pm - 9:37 pmFCO-DSM
16h 17m2 stops
$519Lufthansa
Find Deal
jue., dic. 4 - jue., dic. 11
United Airlines Logo
11:35 am - 7:45 amDSM-FCO
13h 10m1 stop
United Airlines Logo
1:10 pm - 2:20 pmFCO-DSM
32h 10m2 stops
$532United Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
United Airlines Logo
5:15 pm - 4:30 pmDSM-FLR
16h 15m2 stops
United Airlines Logo
6:30 am - 8:48 pmFLR-DSM
21h 18m2 stops
$537United Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
KLM Logo
11:23 am - 8:55 amDSM-FLR
14h 32m2 stops
KLM Logo
6:40 am - 5:03 pmFLR-DSM
17h 23m2 stops
$542KLM
Find Deal
mar., dic. 2 - mar., dic. 9
KLM Logo
2:16 pm - 10:30 amDSM-FCO
13h 14m1 stop
KLM Logo
10:05 am - 8:46 pmFCO-DSM
17h 41m1 stop
$546KLM
Find Deal
jue., dic. 4 - jue., dic. 11
Delta Logo
6:17 am - 7:55 amDSM-FCO
18h 38m1 stop
Delta Logo
12:40 pm - 10:34 pmFCO-DSM
16h 54m1 stop
$555Delta
Find Deal
jue., nov. 27 - vie., dic. 5
Delta Logo
1:15 pm - 10:30 amDSM-FCO
14h 15m1 stop
Delta Logo
12:50 pm - 8:53 pmFCO-DSM
39h 03m2 stops
$574Delta
Find Deal
jue., ene. 1 - lun., ene. 12

Lufthansa flights from Des Moines to Tuscany

Our best Lufthansa deals on Des Moines to Tuscany flight tickets
Lufthansa
Dec 5
DSM6:50 pmDes Moines
16h 40m
2 stops
FLR6:30 pmFlorence Peretola
Dec 12
FLR1:15 pmFlorence Peretola
15h 22m
2 stops
DSM9:37 pmDes Moines
$509
Find similar
Lufthansa
Dec 4
DSM6:50 pmDes Moines
16h 00m
2 stops
FCO5:50 pmRome Fiumicino
Dec 11
FCO12:20 pmRome Fiumicino
16h 17m
2 stops
DSM9:37 pmDes Moines
$519
Find similar
Lufthansa
Dec 2
DSM6:50 pmDes Moines
20h 10m
2 stops
FLR10:00 pmFlorence Peretola
Dec 9
FLR6:30 amFlorence Peretola
22h 07m
2 stops
DSM9:37 pmDes Moines
$538
Find similar

United Airlines flights from Des Moines to Tuscany

Our best United Airlines deals on Des Moines to Tuscany flight tickets
United Airlines
Dec 3
DSM11:35 amDes Moines
13h 10m
1 stop
FCO7:45 amRome Fiumicino
Dec 10
FCO1:10 pmRome Fiumicino
32h 10m
2 stops
DSM2:20 pmDes Moines
$532
Find similar
United Airlines
Dec 3
DSM5:15 pmDes Moines
16h 15m
2 stops
FLR4:30 pmFlorence Peretola
Dec 10
FLR6:30 amFlorence Peretola
21h 18m
2 stops
DSM8:48 pmDes Moines
$537
Find similar
United Airlines
Dec 4
DSM11:35 amDes Moines
13h 10m
1 stop
FCO7:45 amRome Fiumicino
Dec 11
FCO10:55 amRome Fiumicino
36h 17m
2 stops
DSM4:12 pmDes Moines
$539
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Tuscany that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 22, 2025.
Use the filters below to find and compare flights from Des Moines to Tuscany that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

vie. 12/5

8:00 am-9:25 am

2 stops18h 25m

Rome Fiumicino

vie. 12/12

1:10 pm-10:53 am

2 stops28h 43m

$471

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

vie. 12/5

5:34 am-7:55 am

1 stop19h 21m

Rome Fiumicino

vie. 12/12

10:05 am-10:34 pm

1 stop19h 29m

$506

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

vie. 12/5

6:50 pm-6:30 pm

2 stops16h 40m

Florence Peretola

vie. 12/12

1:15 pm-9:37 pm

2 stops15h 22m

$509

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

jue. 12/4

6:50 pm-5:50 pm

2 stops16h 00m

Rome Fiumicino

jue. 12/11

12:20 pm-9:37 pm

2 stops16h 17m

$519

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mié. 12/3

11:35 am-7:45 am

1 stop13h 10m

Rome Fiumicino

mié. 12/10

1:10 pm-2:20 pm

2 stops32h 10m

$532

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mié. 12/3

5:15 pm-4:30 pm

2 stops16h 15m

Florence Peretola

mié. 12/10

6:30 am-8:48 pm

2 stops21h 18m

$537

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mar. 12/2

11:23 am-8:55 am

2 stops14h 32m

Florence Peretola

mar. 12/9

6:40 am-5:03 pm

2 stops17h 23m

$542

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

jue. 12/4

2:16 pm-10:30 am

1 stop13h 14m

Rome Fiumicino

jue. 12/11

10:05 am-8:46 pm

1 stop17h 41m

$546

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

jue. 11/27

6:17 am-7:55 am

1 stop18h 38m

Rome Fiumicino

vie. 12/5

12:40 pm-10:34 pm

1 stop16h 54m

$555

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

jue. 1/1

1:15 pm-10:30 am

1 stop14h 15m

Rome Fiumicino

lun. 1/12

12:50 pm-8:53 pm

2 stops39h 03m

$574

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Tuscany from

How to get the cheapest flight ticket from Des Moines to Tuscany

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Tuscany?

On average, the least expensive day to fly to Tuscany from Des Moines is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $1,244. However, this price may fluctuate depending on the airline, the season, and holidays. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $1,991. These prices are subject to change though, so be sure to set up a Price Alert for flights to Tuscany.

What is the cheapest time of day to depart on your flight to Tuscany?

Our data shows that the cheapest Des Moines to Tuscany flights are usually those with departure times in the afternoon. Our users have found flights to Tuscany in the afternoon for as low as $1,238. In the morning is when there is more demand to fly to Tuscany, so prices are often more expensive at around $1,785 per ticket.

Cheap Des Moines to Tuscany flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Tuscany

Direct flights

None
There are no direct flights from Des Moines to Tuscany. There are no popular flight routes from Des Moines to Tuscany.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Tuscany?

    Prices for flights from Des Moines Airport to Tuscany are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Tuscany?

  • How old do you have to be to fly from Des Moines Airport to Tuscany?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Tuscany.

  • What documentation or ID do you need to fly to Tuscany?

    The travel and health documents required for your trip to Tuscany can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Tuscany. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Tuscany

Compare and see reviews for airlines that fly from Des Moines to Tuscany with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $660Free CancellationRating
7.9
7,977 reviews
Search Delta flights
United AirlinesPriceFrom $790Free CancellationRating
7.4
8,988 reviews
Search United Airlines flights
LufthansaPriceFrom $811Free CancellationRating
6.8
7,507 reviews
Search Lufthansa flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Tuscany?

It is quick and easy to find Des Moines to Tuscany flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Tuscany that suits you.

Can I find flights from Des Moines to Tuscany with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Tuscany from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Tuscany?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Tuscany.

I’m not ready to book a flight from Des Moines to Tuscany right now. Can momondo alert me if prices change?

Price alerts on flights to Tuscany from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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