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Cheap flights from Des Moines to Phoenix from $43

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Phoenix departing on 12/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Phoenix

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:35 pm - 5:45 pmDSM-PHX
3h 10mnonstop
Southwest Logo
4:45 pm - 8:25 pmPHX-DSM
2h 40mnonstop
$177Southwest
Find Deal
Sat, Dec 6 - Sat, Dec 13
American Airlines Logo
5:10 am - 7:30 amDSM-PHX
3h 20mnonstop
American Airlines Logo
8:12 pm - 11:59 pmPHX-DSM
2h 47mnonstop
$178American Airlines
Find Deal
Fri, Dec 12 - Wed, Dec 17
American Airlines Logo
2:34 pm - 4:44 pmDSM-PHX
3h 10mnonstop
American Airlines Logo
4:15 pm - 8:04 pmPHX-DSM
2h 49mnonstop
$179American Airlines
Find Deal
Sat, Jan 24 - Wed, Jan 28
Southwest Logo
8:20 am - 2:05 pmDSM-PHX
6h 45m1 stop
Southwest Logo
11:40 am - 3:30 pmPHX-DSM
2h 50mnonstop
$187Southwest
Find Deal
Fri, Dec 5 - Fri, Dec 12
Multiple Airlines Logo
7:58 pm - 12:44 amDSM-PHX
5h 46m1 stop
Multiple Airlines Logo
4:32 pm - 9:36 pmPHX-DSM
28h 04m2 stops
$188Multiple Airlines
Find Deal
Fri, Dec 5 - Wed, Dec 10
American Airlines Logo
2:24 pm - 4:40 pmDSM-PHX
3h 16mnonstop
American Airlines Logo
1:50 pm - 5:35 pmPHX-DSM
2h 45mnonstop
$189American Airlines
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Sat, Feb 14 - Wed, Feb 18
Frontier Logo
2:41 pm - 8:24 amDSM-PHX
18h 43m1 stop
Frontier Logo
7:30 am - 1:47 pmPHX-DSM
5h 17m1 stop
$201Frontier
Find Deal
Thu, Nov 13 - Mon, Nov 17
Frontier Logo
7:58 pm - 8:06 amDSM-PHX
13h 08m1 stop
Frontier Logo
10:31 pm - 7:44 pmPHX-DSM
20h 13m1 stop
$202Frontier
Find Deal
Fri, Dec 12 - Fri, Dec 19
Delta Logo
4:59 pm - 12:04 amDSM-PHX
8h 05m1 stop
Delta Logo
12:59 am - 10:21 amPHX-DSM
8h 22m1 stop
$217Delta
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Wed, Dec 3 - Thu, Dec 4
Delta Logo
2:59 pm - 9:23 pmDSM-PHX
7h 24m1 stop
Delta Logo
7:05 am - 2:19 pmPHX-DSM
6h 14m1 stop
$244Delta
Find Deal
Fri, Dec 5 - Tue, Dec 9

Southwest flights from Des Moines to Phoenix Sky Harbor Intl Airport

Our best Southwest deals on Des Moines to Phoenix Sky Harbor Intl Airport flight tickets
Southwest
Dec 6
DSM3:35 pmDes Moines
3h 10m
PHX5:45 pmPhoenix Sky Harbor Intl
Dec 13
PHX4:45 pmPhoenix Sky Harbor Intl
2h 40m
DSM8:25 pmDes Moines
$177
Find similar
Southwest
Dec 5
DSM8:20 amDes Moines
6h 45m
1 stop
PHX2:05 pmPhoenix Sky Harbor Intl
Dec 12
PHX11:40 amPhoenix Sky Harbor Intl
2h 50m
DSM3:30 pmDes Moines
$187
Find similar
Southwest
Dec 6
DSM5:25 amDes Moines
5h 35m
1 stop
PHX10:00 amPhoenix Sky Harbor Intl
Dec 13
PHX8:30 amPhoenix Sky Harbor Intl
5h 25m
1 stop
DSM2:55 pmDes Moines
$197
Find similar

Frontier flights from Des Moines to Phoenix Sky Harbor Intl Airport

Our best Frontier deals on Des Moines to Phoenix Sky Harbor Intl Airport flight tickets
Frontier
Nov 7
DSM2:32 pmDes Moines
27h 34m
1 stop
PHX5:06 pmPhoenix Sky Harbor Intl
Nov 12
PHX1:16 pmPhoenix Sky Harbor Intl
23h 40m
1 stop
DSM1:56 pmDes Moines
$181
Find similar
Frontier
Nov 13
DSM2:41 pmDes Moines
18h 43m
1 stop
PHX8:24 amPhoenix Sky Harbor Intl
Nov 17
PHX7:30 amPhoenix Sky Harbor Intl
5h 17m
1 stop
DSM1:47 pmDes Moines
$201
Find similar
Frontier
Dec 12
DSM7:58 pmDes Moines
13h 08m
1 stop
PHX8:06 amPhoenix Sky Harbor Intl
Dec 19
PHX10:31 pmPhoenix Sky Harbor Intl
20h 13m
1 stop
DSM7:44 pmDes Moines
$202
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Phoenix Sky Harbor Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Des Moines to Phoenix Sky Harbor Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 12/6

3:35 pm-5:45 pm

Nonstop3h 10m

Phoenix Sky Harbor Intl

Sat 12/13

4:45 pm-8:25 pm

Nonstop2h 40m

$177

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 12/12

5:10 am-7:30 am

Nonstop3h 20m

Phoenix Sky Harbor Intl

Wed 12/17

8:12 pm-11:59 pm

Nonstop2h 47m

$178

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 1/24

2:34 pm-4:44 pm

Nonstop3h 10m

Phoenix Sky Harbor Intl

Wed 1/28

4:15 pm-8:04 pm

Nonstop2h 49m

$179

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 12/5

8:20 am-2:05 pm

1 stop6h 45m

Phoenix Sky Harbor Intl

Fri 12/12

11:40 am-3:30 pm

Nonstop2h 50m

$187

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 12/5

7:58 pm-12:44 am

1 stop5h 46m

Phoenix Sky Harbor Intl

Wed 12/10

4:32 pm-9:36 pm

2 stops28h 04m

$188

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 2/14

2:24 pm-4:40 pm

Nonstop3h 16m

Phoenix Sky Harbor Intl

Wed 2/18

1:50 pm-5:35 pm

Nonstop2h 45m

$189

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 11/13

2:41 pm-8:24 am

1 stop18h 43m

Phoenix Sky Harbor Intl

Mon 11/17

7:30 am-1:47 pm

1 stop5h 17m

$201

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 12/12

7:58 pm-8:06 am

1 stop13h 08m

Phoenix Sky Harbor Intl

Fri 12/19

10:31 pm-7:44 pm

1 stop20h 13m

$202

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 12/3

4:59 pm-12:04 am

1 stop8h 05m

Phoenix Sky Harbor Intl

Thu 12/4

12:59 am-10:21 am

1 stop8h 22m

$217

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 12/5

2:59 pm-9:23 pm

1 stop7h 24m

Phoenix Sky Harbor Intl

Tue 12/9

7:05 am-2:19 pm

1 stop6h 14m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Phoenix Sky Harbor Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Phoenix Sky Harbor Intl Airport?

In general, October is the cheapest month to fly from Des Moines to Phoenix Sky Harbor Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $293. If you are unable to visit Phoenix Sky Harbor Intl Airport during the month of October, then departing from Des Moines during the month January is also very affordable. Most momondo users find prices during this month for around $294.

What is the cheapest day to depart on your flight to Phoenix Sky Harbor Intl Airport?

On average, the least expensive day to fly to Phoenix Sky Harbor Intl Airport from Des Moines is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $366. However, this price may fluctuate depending on the airline, the season, and holidays. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $488. These prices are subject to change though, so be sure to set up a Price Alert for flights to Phoenix Sky Harbor Intl Airport.

What is the cheapest time of day to depart on your flight to Phoenix Sky Harbor Intl Airport?

In the evening is the cheapest time of day to fly from Des Moines to Phoenix Sky Harbor Intl Airport when you can find flight prices for as low as $230. Flying to Phoenix Sky Harbor Intl Airport in the evening is an ideal time because this is during off-peak travel hours. Try not to purchase tickets in the morning because they tend to be around $397. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Des Moines to Phoenix Sky Harbor Intl flight route?

Fly from Des Moines to Phoenix Sky Harbor Intl for the best Des Moines - Phoenix Sky Harbor Intl flight prices

How far in advance should I book a flight to Phoenix Sky Harbor Intl Airport?

You are more likely to see cheaper flights to Phoenix Sky Harbor Intl Airport from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Phoenix Sky Harbor Intl Airport for around $331 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Phoenix Sky Harbor Intl Airport from Des Moines for as low as $285 on momondo.

What cabin class options are available on Des Moines to Phoenix Sky Harbor Intl flights?

There are 3 cabin classes available to choose from on Des Moines to Phoenix Sky Harbor Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Phoenix Sky Harbor Intl Airport flights?

You could potentially save up to 18% on your flight if you consider stops on a Des Moines to Phoenix Sky Harbor Intl Airport flight.

How have Des Moines to Phoenix Sky Harbor Intl Airport flight prices changed over time?

As of October 2025, prices for Des Moines to Phoenix Sky Harbor Intl Airport flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Phoenix Sky Harbor Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Phoenix Sky Harbor Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Phoenix Sky Harbor Intl Airport (DSM to PHX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Phoenix Sky Harbor Intl Airport

Best Price Found

$158

Fastest flight time

3h 03m

Direct flights

Every day
The best one-way flight to Phoenix Sky Harbor Intl Airport from Des Moines in the past 72 hours is $158. The best round-trip flight deal from Des Moines to Phoenix Sky Harbor Intl Airport found on momondo in the last 72 hours is $294.
The fastest flight from Des Moines to Phoenix Sky Harbor Intl Airport takes 3h 03m
Direct flights go from Des Moines to Phoenix Sky Harbor Intl Airport every day.
Search flight deals

  • How far is Des Moines to Phoenix Sky Harbor Intl by plane?

    Des Moines and Phoenix Sky Harbor Intl are 1149.3 mi apart from one another. A reasonable flight in good conditions will take 3h 10m.

  • When did momondo last update prices for flights from Des Moines Airport to Phoenix Sky Harbor Intl Airport?

    Prices for flights from Des Moines Airport to Phoenix Sky Harbor Intl Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Phoenix Sky Harbor Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Phoenix Sky Harbor Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Phoenix Sky Harbor Intl Airport.

  • What documentation or ID do you need to fly to Phoenix Sky Harbor Intl Airport?

    The necessary travel and health documents for your Phoenix Sky Harbor Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Phoenix Sky Harbor Intl Airport?

  • What is the most popular airline from Des Moines to Phoenix Sky Harbor Intl Airport?

Best airlines flying from Des Moines to Phoenix Sky Harbor Intl Airport

Compare and see reviews for airlines that fly from Des Moines to Phoenix Sky Harbor Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $128Free CancellationRating
5.8
3,123 reviews
Search Frontier flights
Allegiant AirPriceFrom $142Free CancellationRating
7.2
695 reviews
Search Allegiant Air flights
SouthwestPriceFrom $188Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
American AirlinesPriceFrom $193Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights
United AirlinesPriceFrom $234Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
7,993 reviews
Search Delta flights

  • Southwest Flights From Des Moines to Phoenix Sky Harbor Intl Airport

    Across 1 Southwest flight from Des Moines to Phoenix Sky Harbor Intl Airport this week, the average price was $333, with the best Southwest deals starting from $188 round-trip. 4,242 users have rated Southwest on momondo, with an average score of 8.0/10.

  • American Airlines Flights From Des Moines to Phoenix Sky Harbor Intl Airport

    Across 11,030 American Airlines reviews on momondo, the average score is 7.2/10. American Airlines flies from Des Moines to Phoenix Sky Harbor Intl Airport about 6 times each week, with ticket deals ranging from $193 to $343. Price data is based on momondo searches in the last 72 hours.

Traveling to a place near Phoenix?

Book flights to Phoenix if you plan to visit one of these locations
Scottsdale
Mesa
Tempe
Glendale
Chandler
Gilbert
Peoria
Surprise
Casa Grande
Goodyear
Buckeye
Payson
Apache Junction
Wickenburg
Avondale
Paradise Valley
Camp Verde
Fountain Hills
Litchfield Park
Cave Creek

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Phoenix?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Phoenix from Des Moines.

Can I find flights from Des Moines to Phoenix with flexible booking policies on momondo?

momondo does allow users to show only those flights to Phoenix from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Phoenix?

Once you have performed a search for Des Moines to Phoenix flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Phoenix right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Phoenix now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Phoenix and let you know when they change.

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