What is the cheapest airline that flies from Des Moines to Chicago O'Hare Intl?

Southwest, United Airlines, and Delta are the most popular carriers operating from Des Moines to Chicago O'Hare Intl

How many flights depart from Des Moines to Chicago O'Hare Intl Airport on average per day?

As of March 2026, there are 20 flights per day flying from Des Moines to Chicago O'Hare Intl Airport. The most common time of day flights depart is 10:00AM, with 52% of flights taking off at noon.

How many flights depart from Des Moines to Chicago O'Hare Intl Airport on average per week?

As of March 2026, there are 145 flights per week flying from Des Moines to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Wed, with 29% of flights taking off on this day.

When did momondo last update prices for flights from Des Moines Airport to Chicago O'Hare Intl Airport?

Prices for flights from Des Moines Airport to Chicago O'Hare Intl Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Chicago O'Hare Intl Airport?

As of March 2026, there are 2 operators available to choose from for flights from Des Moines Airport to Chicago O'Hare Intl Airport.

How old do you have to be to fly from Des Moines Airport to Chicago O'Hare Intl Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Chicago O'Hare Intl Airport.

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

The necessary travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$79 Cheap Flights from Des Moines to Chicago O'Hare Intl Airport in 2026

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Enter your travel dates to find the best prices.

3:21 pm - 4:53 pm

DSM

ORD

1h 32mnonstop

8:00 pm - 9:32 pm

ORD

DSM

1h 32mnonstop

$157United Airlines

Tue, Mar 31 - Tue, Apr 7

7:44 pm - 9:19 pm

DSM

ORD

1h 35mnonstop

10:26 pm - 11:48 pm

ORD

DSM

1h 22mnonstop

$164American Airlines

Wed, Apr 1 - Sat, Apr 4

10:04 am - 11:37 am

DSM

ORD

1h 33mnonstop

10:29 pm - 11:49 pm

ORD

DSM

1h 20mnonstop

$177American Airlines

Tue, Mar 31 - Tue, Apr 7

8:04 am - 9:36 am

DSM

ORD

1h 32mnonstop

5:50 pm - 7:26 pm

ORD

DSM

1h 36mnonstop

$179United Airlines

Tue, Apr 28 - Sat, May 2

6:40 am - 1:55 pm

DSM

ORD

7h 15m

1 stop

10:30 am - 9:15 pm

ORD

DSM

10h 45m

1 stop

$182Southwest

Tue, Mar 31 - Tue, Apr 7

10:28 am - 4:43 pm

DSM

ORD

6h 15m

1 stop

9:50 am - 4:54 pm

ORD

DSM

7h 04m

1 stop

$184Delta

Wed, Apr 1 - Sat, Apr 4

2:04 pm - 3:41 pm

DSM

ORD

1h 37mnonstop

12:57 pm - 2:24 pm

ORD

DSM

1h 27mnonstop

$187United Airlines

Wed, Mar 25 - Fri, Mar 27

1:10 pm - 2:46 pm

DSM

ORD

1h 36mnonstop

10:53 pm - 12:33 am

ORD

DSM

1h 40mnonstop

$192United Airlines

Sat, Apr 25 - Fri, May 29

5:00 am - 6:29 am

DSM

ORD

1h 29mnonstop

7:25 am - 8:49 am

ORD

DSM

1h 24mnonstop

$199American Airlines

Wed, Apr 1 - Sat, Apr 4

1:10 pm - 2:46 pm

DSM

ORD

1h 36mnonstop

9:40 pm - 11:17 pm

ORD

DSM

1h 37mnonstop

$201United Airlines

Mon, Mar 30 - Sat, Apr 11

Southwest flights from Des Moines to Chicago O'Hare Intl Airport

Our best Southwest deals on Des Moines to Chicago O'Hare Intl Airport flight tickets

Southwest

Mar 31

DSM6:40 amDes Moines

7h 15m

1 stop

ORD1:55 pmChicago O'Hare Intl

Apr 7

ORD10:30 amChicago O'Hare Intl

10h 45m

1 stop

DSM9:15 pmDes Moines

$182

Southwest

Apr 25

DSM6:40 amDes Moines

7h 40m

1 stop

ORD2:20 pmChicago O'Hare Intl

May 29

ORD8:00 amChicago O'Hare Intl

10h 35m

1 stop

DSM6:35 pmDes Moines

$212

Southwest

Mar 30

DSM6:50 amDes Moines

8h 15m

1 stop

ORD3:05 pmChicago O'Hare Intl

Apr 14

ORD10:30 amChicago O'Hare Intl

10h 45m

1 stop

DSM9:15 pmDes Moines

$226

American Airlines flights from Des Moines to Chicago O'Hare Intl Airport

Our best American Airlines deals on Des Moines to Chicago O'Hare Intl Airport flight tickets

American Airlines

Mar 31

DSM10:04 amDes Moines

1h 33m

ORD11:37 amChicago O'Hare Intl

Apr 7

ORD10:29 pmChicago O'Hare Intl

1h 20m

DSM11:49 pmDes Moines

$177

American Airlines

Apr 1

DSM7:44 pmDes Moines

1h 35m

ORD9:19 pmChicago O'Hare Intl

Apr 4

ORD10:26 pmChicago O'Hare Intl

1h 22m

DSM11:48 pmDes Moines

$199

American Airlines

Apr 15

DSM12:00 pmDes Moines

1h 47m

ORD1:47 pmChicago O'Hare Intl

Apr 22

ORD6:53 amChicago O'Hare Intl

1h 33m

DSM8:26 amDes Moines

$202

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 3/31

3:21 pm-4:53 pm

Nonstop1h 32m

Chicago O'Hare Intl

Tue 4/7

8:00 pm-9:32 pm

Nonstop1h 32m

$157

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 4/1

7:44 pm-9:19 pm

Nonstop1h 35m

Chicago O'Hare Intl

Sat 4/4

10:26 pm-11:48 pm

Nonstop1h 22m

$164

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 3/31

10:04 am-11:37 am

Nonstop1h 33m

Chicago O'Hare Intl

Tue 4/7

10:29 pm-11:49 pm

Nonstop1h 20m

$177

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 4/28

8:04 am-9:36 am

Nonstop1h 32m

Chicago O'Hare Intl

Sat 5/2

5:50 pm-7:26 pm

Nonstop1h 36m

$179

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 3/31

6:40 am-1:55 pm

1 stop7h 15m

Chicago O'Hare Intl

Tue 4/7

10:30 am-9:15 pm

1 stop10h 45m

$182

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 4/1

10:28 am-4:43 pm

1 stop6h 15m

Chicago O'Hare Intl

Sat 4/4

9:50 am-4:54 pm

1 stop7h 04m

$184

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 3/25

2:04 pm-3:41 pm

Nonstop1h 37m

Chicago O'Hare Intl

Fri 3/27

12:57 pm-2:24 pm

Nonstop1h 27m

$187

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 4/25

1:10 pm-2:46 pm

Nonstop1h 36m

Chicago O'Hare Intl

Fri 5/29

10:53 pm-12:33 am

Nonstop1h 40m

$192

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 4/1

5:00 am-6:29 am

Nonstop1h 29m

Chicago O'Hare Intl

Sat 4/4

7:25 am-8:49 am

Nonstop1h 24m

$199

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Mon 3/30

1:10 pm-2:46 pm

Nonstop1h 36m

Chicago O'Hare Intl

Sat 4/11

9:40 pm-11:17 pm

Nonstop1h 37m

$201

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of February is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Des Moines averaging around $224.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $532. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $844.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Des Moines in the morning is the least expensive time of day to depart. momondo users have found prices as low as $531 when looking at flights departing in the morning. Try not to purchase tickets at noon because they tend to be around $1,010. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Des Moines to Chicago O'Hare Intl flight route?

Fly from Des Moines to Chicago O'Hare Intl for the best Des Moines - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $249 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Des Moines for as low as $187 on momondo.

What cabin class options are available on Des Moines to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Des Moines to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Chicago O'Hare Intl Airport.

How have Des Moines to Chicago O'Hare Intl Airport flight prices changed over time?

As of March 2026, prices for Des Moines to Chicago O'Hare Intl Airport flights are approximately 35% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Chicago O'Hare Intl Airport (DSM to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Chicago O'Hare Intl Airport

Best Price Found	$208
Fastest flight time	1h 32m
Direct flights	Every day

The best one-way flight to Chicago O'Hare Intl Airport from Des Moines in the past 72 hours is $208. The best round-trip flight deal from Des Moines to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $403.

The fastest flight from Des Moines to Chicago O'Hare Intl Airport takes 1h 32m

Direct flights go from Des Moines to Chicago O'Hare Intl Airport every day.

Search flight deals

How far is Des Moines to Chicago O'Hare Intl by plane?
Des Moines and Chicago O'Hare Intl are 295.9 mi apart from one another. Flights usually cover this in 1h 32m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Chicago O'Hare Intl Airport?
Prices for flights from Des Moines Airport to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Chicago O'Hare Intl Airport?
As of March 2026, there are 2 operators available to choose from for flights from Des Moines Airport to Chicago O'Hare Intl Airport.
How old do you have to be to fly from Des Moines Airport to Chicago O'Hare Intl Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The necessary travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Des Moines to Chicago O'Hare Intl Airport?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Des Moines to Chicago O'Hare Intl Airport is Airbus A319 (16.05% of total bookings). The next most popular plane models are Embraer 175 (14.71%), Embraer 170 (12.51%), and Canadair (Bombardier) Regional Jet 700 (12.51%).
What is the most popular airline from Des Moines to Chicago O'Hare Intl Airport?
momondo data reveals that the most frequently booked airline on the route from Des Moines to Chicago O'Hare Intl Airport is United Airlines, representing 55% of all bookings. The subsequent popular airline is American Airlines at 45%.

Best airlines flying from Des Moines to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Des Moines to Chicago O'Hare Intl Airport with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $148	Free Cancellation	Rating 7.1 11,378 reviews		Search American Airlines flights
United Airlines	PriceFrom $189	Free Cancellation	Rating 7.4 9,382 reviews		Search United Airlines flights

United Airlines Flights From Des Moines to Chicago O'Hare Intl Airport
United Airlines operates around 10 flights from Des Moines to Chicago O'Hare Intl Airport every week. The average price of these flights found in the last 72 hours has been $254, but momondo users have found United Airlines deals from Des Moines to Chicago O'Hare Intl Airport from as low as $189 round-trip. United Airlines has been scored 7.4/10 in 9,382 reviews.
American Airlines Flights From Des Moines to Chicago O'Hare Intl Airport
Another popular option for Des Moines to Chicago O'Hare Intl Airport flights is American Airlines (7.1/10, 11,378 ratings). American Airlines flies from Des Moines to Chicago O'Hare Intl Airport around 9 times per week, with deals starting from $148 round-trip and rising to an average price of around $230.

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Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Des Moines.

Can I find flights from Des Moines to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Des Moines.

I’m not ready to book a flight from Des Moines to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Des Moines to Chicago from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Chicago departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from Des Moines to Chicago O'Hare Intl Airport

Our best Southwest deals on Des Moines to Chicago O'Hare Intl Airport flight tickets

American Airlines flights from Des Moines to Chicago O'Hare Intl Airport

Our best American Airlines deals on Des Moines to Chicago O'Hare Intl Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Chicago O'Hare Intl Airport that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from Des Moines to Chicago O'Hare Intl Airport

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest Des Moines to Chicago O'Hare Intl flight route?

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

What cabin class options are available on Des Moines to Chicago O'Hare Intl flights?

Can stopping save me money on Des Moines to Chicago O'Hare Intl Airport flights?

How have Des Moines to Chicago O'Hare Intl Airport flight prices changed over time?

What is the cheapest airline that flies from Des Moines to Chicago O'Hare Intl?

How many flights depart from Des Moines to Chicago O'Hare Intl Airport on average per day?

How many flights depart from Des Moines to Chicago O'Hare Intl Airport on average per week?

When to book flights from Des Moines to Chicago O'Hare Intl Airport

Cheap Des Moines to Chicago O'Hare Intl Airport (DSM to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Chicago O'Hare Intl Airport

Best Price Found

Fastest flight time

Direct flights

Best airlines flying from Des Moines to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Des Moines to Chicago O'Hare Intl Airport with momondo

United Airlines Flights From Des Moines to Chicago O'Hare Intl Airport

American Airlines Flights From Des Moines to Chicago O'Hare Intl Airport

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List of cabin classes available on flights landing in Chicago. Availability may vary depending on flight origin and airline.

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