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Cheap flights from Des Moines to Mexico City Federal District from $191

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico City Federal District departing on 12/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Mexico City Federal District

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:56 pm - 10:00 pmDSM-MEX
31h 04m2 stops
Multiple Airlines Logo
3:20 pm - 9:36 pmMEX-DSM
6h 16m1 stop
$456Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:56 pm - 10:00 pmDSM-MEX
31h 04m2 stops
Multiple Airlines Logo
3:20 pm - 9:36 pmMEX-DSM
6h 16m1 stop
$478Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:56 pm - 10:00 pmDSM-MEX
31h 04m2 stops
Multiple Airlines Logo
3:20 pm - 9:36 pmMEX-DSM
6h 16m1 stop
$480Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:56 pm - 10:00 pmDSM-MEX
31h 04m2 stops
Multiple Airlines Logo
3:20 pm - 9:36 pmMEX-DSM
6h 16m1 stop
$482Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
5:25 pm - 9:55 amDSM-MEX
16h 30m1 stop
American Airlines Logo
6:00 am - 2:55 pmMEX-DSM
8h 55m1 stop
$498American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
5:25 pm - 9:55 amDSM-MEX
16h 30m1 stop
American Airlines Logo
8:00 am - 2:55 pmMEX-DSM
6h 55m1 stop
$542American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
United Airlines Logo
8:15 am - 4:45 pmDSM-MEX
8h 30m1 stop
United Airlines Logo
5:45 am - 2:12 pmMEX-DSM
8h 27m1 stop
$543United Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Delta Logo
6:50 am - 9:40 pmDSM-MEX
14h 50m2 stops
Delta Logo
7:00 am - 10:34 pmMEX-DSM
15h 34m2 stops
$588Delta
Find Deal
Sat, Dec 6 - Sat, Dec 13
Delta Logo
6:17 am - 8:40 pmDSM-MEX
14h 23m2 stops
Delta Logo
9:40 am - 10:34 pmMEX-DSM
12h 54m2 stops
$605Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
Frontier Logo
2:32 pm - 10:30 pmDSM-MEX
31h 58m2 stops
Frontier Logo
3:45 pm - 1:47 pmMEX-DSM
22h 02m2 stops
$610Frontier
Find Deal
Sun, Nov 2 - Sat, Nov 8

American Airlines flights from Des Moines to Mexico City Federal District

Our best American Airlines deals on Des Moines to Mexico City Federal District flight tickets
American Airlines
Dec 4
DSM5:25 pmDes Moines
16h 30m
1 stop
MEX9:55 amMexico City Benito Juarez
Dec 11
MEX6:00 amMexico City Benito Juarez
8h 55m
1 stop
DSM2:55 pmDes Moines
$498
Find similar
American Airlines
Dec 4
DSM5:25 pmDes Moines
16h 30m
1 stop
MEX9:55 amMexico City Benito Juarez
Dec 11
MEX8:00 amMexico City Benito Juarez
6h 55m
1 stop
DSM2:55 pmDes Moines
$542
Find similar
American Airlines
Dec 9
DSM6:00 pmDes Moines
15h 55m
1 stop
MEX9:55 amMexico City Benito Juarez
Dec 16
MEX8:00 amMexico City Benito Juarez
6h 51m
1 stop
DSM2:51 pmDes Moines
$553
Find similar

United Airlines flights from Des Moines to Mexico City Federal District

Our best United Airlines deals on Des Moines to Mexico City Federal District flight tickets
United Airlines
Dec 3
DSM8:15 amDes Moines
8h 30m
1 stop
MEX4:45 pmMexico City Benito Juarez
Dec 10
MEX5:45 amMexico City Benito Juarez
8h 27m
1 stop
DSM2:12 pmDes Moines
$543
Find similar
United Airlines
Oct 27
DSM1:05 pmDes Moines
21h 00m
2 stops
MEX9:05 amMexico City Benito Juarez
Nov 7
MEX5:45 amMexico City Benito Juarez
10h 27m
2 stops
DSM4:12 pmDes Moines
$755
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 26, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

2:56 pm-10:00 pm

2 stops31h 04m

Mexico City Benito Juarez

Thu 12/11

3:20 pm-9:36 pm

1 stop6h 16m

$456

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

2:56 pm-10:00 pm

2 stops31h 04m

Mexico City Benito Juarez

Thu 12/11

3:20 pm-9:36 pm

1 stop6h 16m

$478

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

2:56 pm-10:00 pm

2 stops31h 04m

Mexico City Benito Juarez

Thu 12/11

3:20 pm-9:36 pm

1 stop6h 16m

$480

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

2:56 pm-10:00 pm

2 stops31h 04m

Mexico City Benito Juarez

Thu 12/11

3:20 pm-9:36 pm

1 stop6h 16m

$482

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

5:25 pm-9:55 am

1 stop16h 30m

Mexico City Benito Juarez

Thu 12/11

6:00 am-2:55 pm

1 stop8h 55m

$498

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

5:25 pm-9:55 am

1 stop16h 30m

Mexico City Benito Juarez

Thu 12/11

8:00 am-2:55 pm

1 stop6h 55m

$542

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 12/3

8:15 am-4:45 pm

1 stop8h 30m

Mexico City Benito Juarez

Wed 12/10

5:45 am-2:12 pm

1 stop8h 27m

$543

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 12/6

6:50 am-9:40 pm

2 stops14h 50m

Mexico City Benito Juarez

Sat 12/13

7:00 am-10:34 pm

2 stops15h 34m

$588

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Tue 12/9

6:17 am-8:40 pm

2 stops14h 23m

Mexico City Benito Juarez

Tue 12/16

9:40 am-10:34 pm

2 stops12h 54m

$605

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 11/2

2:32 pm-10:30 pm

2 stops31h 58m

Mexico City Benito Juarez

Sat 11/8

3:45 pm-1:47 pm

2 stops22h 02m

$610

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Des Moines to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of August, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $543.

What is the cheapest day to depart on your flight to Mexico City Federal District?

The cheapest day to depart on your flight to Mexico City Federal District is on a Thursday when prices can be found for as low as $610. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Mexico City Federal District for around $864.

What is the cheapest time of day to depart on your flight to Mexico City Federal District?

The cheapest time of day to fly to Mexico City Federal District is in the morning when flights can be purchased for as low as $692. At noon is when there is more demand to fly to Mexico City Federal District, so prices are often more expensive at around $822 per ticket.

Cheap Des Moines to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico City Federal District

Direct flights

None
There are no direct flights from Des Moines to Mexico City Federal District. There are no popular flight routes from Des Moines to Mexico City Federal District.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico City Federal District?

    Prices for flights from Des Moines Airport to Mexico City Federal District are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico City Federal District?

  • How old do you have to be to fly from Des Moines Airport to Mexico City Federal District?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The necessary travel and health documents for your Mexico City Federal District trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico City Federal District

Compare and see reviews for airlines that fly from Des Moines to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
7.9
7,997 reviews
Search Delta flights
United AirlinesPriceFrom $379Free CancellationRating
7.4
8,999 reviews
Search United Airlines flights
American AirlinesPriceFrom $420Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico City Federal District?

Finding the right flight to Mexico City Federal District from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City Federal District quick and easy, saving you time and money.

Can I find flights from Des Moines to Mexico City Federal District with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico City Federal District from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico City Federal District?

momondo helps you find the best flight between Des Moines and Mexico City Federal District by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico City Federal District right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Mexico City Federal District flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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