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Cheap flights from Des Moines to Mexico City Federal District from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico City Federal District departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Mexico City Federal District

Cheap round-trip flights

Logo
3:40 pm - 9:10 pmDSM-MEX
30h 30m1 stop
Logo
10:20 pm - 10:00 amMEX-DSM
35h 40m2 stops
$428
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Mon, Oct 27 - Tue, Nov 4
Logo
8:25 am - 10:55 pmDSM-MEX
15h 30m2 stops
Logo
11:45 am - 10:37 pmMEX-DSM
9h 52m1 stop
$445
Find Deal
Fri, Sep 26 - Fri, Oct 3
American Airlines Logo
4:09 pm - 8:45 pmDSM-MEX
5h 36m1 stop
American Airlines Logo
3:00 pm - 3:24 pmMEX-DSM
23h 24m1 stop
$495American Airlines
Find Deal
Fri, Sep 26 - Fri, Oct 3
Frontier Logo
2:25 pm - 5:00 pmDSM-MEX
27h 35m1 stop
Frontier Logo
8:10 am - 1:40 pmMEX-DSM
28h 30m1 stop
$534Frontier
Find Deal
Sun, Sep 21 - Sun, Sep 28
Frontier Logo
2:25 pm - 5:00 pmDSM-MEX
27h 35m1 stop
Frontier Logo
8:10 am - 1:40 pmMEX-DSM
28h 30m1 stop
$537Frontier
Find Deal
Sun, Sep 21 - Sun, Sep 28
Aeromexico Logo
10:50 am - 10:05 pmDSM-MEX
12h 15m2 stops
Aeromexico Logo
8:25 am - 10:30 pmMEX-DSM
14h 05m2 stops
$542Aeromexico
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Wed, Oct 29 - Tue, Nov 4
American Airlines Logo
5:10 am - 4:15 pmDSM-MEX
12h 05m1 stop
American Airlines Logo
3:00 pm - 9:04 amMEX-DSM
17h 04m1 stop
$543American Airlines
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Fri, Sep 26 - Fri, Oct 3
Delta Logo
7:03 am - 8:25 pmDSM-MEX
14h 22m2 stops
Delta Logo
9:30 am - 9:03 pmMEX-DSM
11h 33m2 stops
$547Delta
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Tue, Oct 28 - Thu, Nov 6
Aeromexico Logo
7:00 am - 12:40 pmDSM-MEX
6h 40m1 stop
Aeromexico Logo
9:50 pm - 10:37 pmMEX-DSM
23h 47m2 stops
$554Aeromexico
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Sun, Sep 21 - Sun, Sep 28
Delta Logo
6:30 pm - 8:10 amDSM-MEX
14h 40m2 stops
Delta Logo
9:01 am - 10:37 pmMEX-DSM
12h 36m2 stops
$567Delta
Find Deal
Sun, Sep 21 - Sun, Sep 28

American Airlines flights from Des Moines to Mexico City Federal District

Our best American Airlines deals on Des Moines to Mexico City Federal District flight tickets
American Airlines
Sep 26
DSM4:09 pmDes Moines
5h 36m
1 stop
MEX8:45 pmMexico City Benito Juarez
Oct 3
MEX3:00 pmMexico City Benito Juarez
23h 24m
1 stop
DSM3:24 pmDes Moines
$495
Find similar
American Airlines
Sep 26
DSM5:10 amDes Moines
12h 05m
1 stop
MEX4:15 pmMexico City Benito Juarez
Oct 3
MEX3:00 pmMexico City Benito Juarez
17h 04m
1 stop
DSM9:04 amDes Moines
$543
Find similar
American Airlines
Sep 26
DSM4:09 pmDes Moines
5h 36m
1 stop
MEX8:45 pmMexico City Benito Juarez
Oct 3
MEX3:00 pmMexico City Benito Juarez
17h 04m
1 stop
DSM9:04 amDes Moines
$545
Find similar

Aeromexico flights from Des Moines to Mexico City Federal District

Our best Aeromexico deals on Des Moines to Mexico City Federal District flight tickets
Aeromexico
Oct 29
DSM10:50 amDes Moines
12h 15m
2 stops
MEX10:05 pmMexico City Benito Juarez
Nov 4
MEX8:25 amMexico City Benito Juarez
14h 05m
2 stops
DSM10:30 pmDes Moines
$542
Find similar
Aeromexico
Sep 21
DSM7:00 amDes Moines
6h 40m
1 stop
MEX12:40 pmMexico City Benito Juarez
Sep 28
MEX9:50 pmMexico City Benito Juarez
23h 47m
2 stops
DSM10:37 pmDes Moines
$554
Find similar
Aeromexico
Sep 27
DSM11:25 amDes Moines
9h 15m
1 stop
MEX7:40 pmMexico City Benito Juarez
Oct 4
MEX11:15 amMexico City Benito Juarez
10h 22m
1 stop
DSM10:37 pmDes Moines
$561
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 10/27

3:40 pm-9:10 pm

1 stop30h 30m

Mexico City Benito Juarez

Tue 11/4

10:20 pm-10:00 am

2 stops35h 40m

$428

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 9/26

8:25 am-10:55 pm

2 stops15h 30m

Mexico City Benito Juarez

Fri 10/3

11:45 am-10:37 pm

1 stop9h 52m

$445

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 9/26

4:09 pm-8:45 pm

1 stop5h 36m

Mexico City Benito Juarez

Fri 10/3

3:00 pm-3:24 pm

1 stop23h 24m

$495

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 9/21

2:25 pm-5:00 pm

1 stop27h 35m

Mexico City Benito Juarez

Sun 9/28

8:10 am-1:40 pm

1 stop28h 30m

$534

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 9/21

2:25 pm-5:00 pm

1 stop27h 35m

Mexico City Benito Juarez

Sun 9/28

8:10 am-1:40 pm

1 stop28h 30m

$537

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 10/29

10:50 am-10:05 pm

2 stops12h 15m

Mexico City Benito Juarez

Tue 11/4

8:25 am-10:30 pm

2 stops14h 05m

$542

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 9/26

5:10 am-4:15 pm

1 stop12h 05m

Mexico City Benito Juarez

Fri 10/3

3:00 pm-9:04 am

1 stop17h 04m

$543

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Tue 10/28

7:03 am-8:25 pm

2 stops14h 22m

Mexico City Benito Juarez

Thu 11/6

9:30 am-9:03 pm

2 stops11h 33m

$547

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 9/21

7:00 am-12:40 pm

1 stop6h 40m

Mexico City Benito Juarez

Sun 9/28

9:50 pm-10:37 pm

2 stops23h 47m

$554

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 9/21

6:30 pm-8:10 am

2 stops14h 40m

Mexico City Benito Juarez

Sun 9/28

9:01 am-10:37 pm

2 stops12h 36m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Des Moines to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of August, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $543.

What is the cheapest day to depart on your flight to Mexico City Federal District?

The cheapest day to depart on your flight to Mexico City Federal District is on a Thursday when prices can be found for as low as $610. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Mexico City Federal District for around $864.

What is the cheapest time of day to depart on your flight to Mexico City Federal District?

The cheapest time of day to fly to Mexico City Federal District is in the morning when flights can be purchased for as low as $692. At noon is when there is more demand to fly to Mexico City Federal District, so prices are often more expensive at around $822 per ticket.

Cheap Des Moines to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico City Federal District

Best Price Found

$265

Fastest flight time

5h 36m

Direct flights

None

Airports in Mexico City Federal District

1 airport
The best one-way flight to Mexico City Federal District from Des Moines in the past 72 hours is $265. The best round-trip flight deal from Des Moines to Mexico City Federal District found on momondo in the last 72 hours is $428.
The fastest flight from Des Moines to Mexico City Federal District takes 5h 36m
There are no direct flights from Des Moines to Mexico City Federal District. Popular non-direct route for this connection is Des Moines Airport - Mexico City Benito Juarez Airport.
There is 1 airport near Mexico City Federal District: Mexico City Benito Juarez (MEX)
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico City Federal District?

    Prices for flights from Des Moines Airport to Mexico City Federal District are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico City Federal District?

  • How old do you have to be to fly from Des Moines Airport to Mexico City Federal District?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The necessary travel and health documents for your Mexico City Federal District trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico City Federal District

Compare and see reviews for airlines that fly from Des Moines to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
8.0
7,980 reviews
Search Delta flights
American AirlinesPriceFrom $527Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $537Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico City Federal District?

Finding the right flight to Mexico City Federal District from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City Federal District quick and easy, saving you time and money.

Can I find flights from Des Moines to Mexico City Federal District with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico City Federal District from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico City Federal District?

momondo helps you find the best flight between Des Moines and Mexico City Federal District by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico City Federal District right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Mexico City Federal District flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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