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Cheap flights from Des Moines to Mexico City Federal District from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico City Federal District departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Mexico City Federal District

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:17 pm - 5:05 pm
DSM
-
MEX
21h 48m
1 stop
Multiple Airlines Logo
10:50 pm - 4:02 pm
MEX
-
DSM
40h 12m
2 stops
$427Multiple Airlines
Mon, Mar 2 - Mon, Mar 9
Multiple Airlines Logo
3:32 pm - 8:05 pm
DSM
-
MEX
29h 33m
1 stop
Multiple Airlines Logo
10:05 am - 1:46 pm
MEX
-
DSM
50h 41m
2 stops
$460Multiple Airlines
Mon, Apr 13 - Tue, Apr 21
Multiple Airlines Logo
7:17 pm - 1:00 am
DSM
-
MEX
29h 43m
2 stops
Multiple Airlines Logo
8:10 am - 6:32 pm
MEX
-
DSM
10h 22m
1 stop
$488Multiple Airlines
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
7:17 pm - 5:05 pm
DSM
-
MEX
21h 48m
1 stop
Multiple Airlines Logo
8:10 am - 6:32 pm
MEX
-
DSM
10h 22m
1 stop
$498Multiple Airlines
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
7:17 pm - 5:05 pm
DSM
-
MEX
21h 48m
1 stop
Multiple Airlines Logo
8:10 am - 7:16 pm
MEX
-
DSM
10h 06m
1 stop
$501Multiple Airlines
Mon, Mar 2 - Mon, Mar 9
Multiple Airlines Logo
7:27 pm - 5:05 pm
DSM
-
MEX
21h 38m
1 stop
Multiple Airlines Logo
10:00 pm - 7:16 pm
MEX
-
DSM
20h 16m
2 stops
$506Multiple Airlines
Thu, Feb 26 - Tue, Mar 17
Multiple Airlines Logo
7:27 pm - 10:30 pm
DSM
-
MEX
27h 03m
2 stops
Multiple Airlines Logo
8:10 am - 7:16 pm
MEX
-
DSM
10h 06m
1 stop
$510Multiple Airlines
Thu, Feb 26 - Wed, Mar 18
Multiple Airlines Logo
7:27 pm - 5:05 pm
DSM
-
MEX
21h 38m
1 stop
Multiple Airlines Logo
10:25 am - 7:16 pm
MEX
-
DSM
31h 51m
2 stops
$525Multiple Airlines
Thu, Feb 26 - Tue, Mar 17
United Airlines Logo
8:20 am - 3:40 pm
DSM
-
MEX
8h 20m
1 stop
United Airlines Logo
8:05 am - 4:10 pm
MEX
-
DSM
7h 05m
1 stop
$559United Airlines
Mon, Apr 13 - Tue, Apr 21
Delta Logo
11:33 am - 7:45 pm
DSM
-
MEX
9h 12m
1 stop
Delta Logo
7:05 am - 10:38 pm
MEX
-
DSM
14h 33m
2 stops
$563Delta
Wed, Mar 18 - Thu, Mar 26

Delta flights from Des Moines to Mexico City Federal District

Our best Delta deals on Des Moines to Mexico City Federal District flight tickets
Delta
Mar 18
DSM11:33 amDes Moines
9h 12m
1 stop
MEX7:45 pmMexico City Benito Juarez
Mar 26
MEX7:05 amMexico City Benito Juarez
14h 33m
2 stops
DSM10:38 pmDes Moines
$563
Delta
Feb 26
DSM10:40 amDes Moines
11h 55m
2 stops
MEX10:35 pmMexico City Benito Juarez
Mar 17
MEX9:55 amMexico City Benito Juarez
10h 15m
2 stops
DSM9:10 pmDes Moines
$577
Delta
May 15
DSM10:15 amDes Moines
12h 55m
2 stops
MEX10:10 pmMexico City Benito Juarez
May 20
MEX8:50 amMexico City Benito Juarez
11h 27m
2 stops
DSM9:17 pmDes Moines
$583

American Airlines flights from Des Moines to Mexico City Federal District

Our best American Airlines deals on Des Moines to Mexico City Federal District flight tickets
American Airlines
Feb 5
DSM6:07 amDes Moines
7h 13m
1 stop
MEX1:20 pmMexico City Benito Juarez
Feb 17
MEX4:55 pmMexico City Benito Juarez
20h 33m
1 stop
DSM1:28 pmDes Moines
$567
American Airlines
Mar 18
DSM7:27 pmDes Moines
19h 48m
1 stop
MEX2:15 pmMexico City Benito Juarez
Mar 26
MEX10:20 amMexico City Benito Juarez
10h 39m
1 stop
DSM9:59 pmDes Moines
$579
American Airlines
Mar 18
DSM11:17 amDes Moines
12h 05m
1 stop
MEX10:22 pmMexico City Benito Juarez
Mar 26
MEX10:20 amMexico City Benito Juarez
10h 39m
1 stop
DSM9:59 pmDes Moines
$607

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 3/2

7:17 pm-5:05 pm

1 stop21h 48m

Mexico City Benito Juarez

Mon 3/9

10:50 pm-4:02 pm

2 stops40h 12m

$427

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 4/13

3:32 pm-8:05 pm

1 stop29h 33m

Mexico City Benito Juarez

Tue 4/21

10:05 am-1:46 pm

2 stops50h 41m

$460

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 2/13

7:17 pm-1:00 am

2 stops29h 43m

Mexico City Benito Juarez

Mon 2/16

8:10 am-6:32 pm

1 stop10h 22m

$488

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 2/13

7:17 pm-5:05 pm

1 stop21h 48m

Mexico City Benito Juarez

Mon 2/16

8:10 am-6:32 pm

1 stop10h 22m

$498

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 3/2

7:17 pm-5:05 pm

1 stop21h 48m

Mexico City Benito Juarez

Mon 3/9

8:10 am-7:16 pm

1 stop10h 06m

$501

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/26

7:27 pm-5:05 pm

1 stop21h 38m

Mexico City Benito Juarez

Tue 3/17

10:00 pm-7:16 pm

2 stops20h 16m

$506

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/26

7:27 pm-10:30 pm

2 stops27h 03m

Mexico City Benito Juarez

Wed 3/18

8:10 am-7:16 pm

1 stop10h 06m

$510

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/26

7:27 pm-5:05 pm

1 stop21h 38m

Mexico City Benito Juarez

Tue 3/17

10:25 am-7:16 pm

2 stops31h 51m

$525

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 4/13

8:20 am-3:40 pm

1 stop8h 20m

Mexico City Benito Juarez

Tue 4/21

8:05 am-4:10 pm

1 stop7h 05m

$559

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 3/18

11:33 am-7:45 pm

1 stop9h 12m

Mexico City Benito Juarez

Thu 3/26

7:05 am-10:38 pm

2 stops14h 33m

$563

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Des Moines to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of August, then departing from Des Moines during the month February is also very affordable. Most momondo users find prices during this month for around $549.

Cheap Des Moines to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico City Federal District

Fastest flight time

9h 06m

Direct flights

None
The fastest flight from Des Moines to Mexico City Federal District takes 9h 06m
There are no direct flights from Des Moines to Mexico City Federal District. There are no popular flight routes from Des Moines to Mexico City Federal District.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico City Federal District?

    Prices for flights from Des Moines Airport to Mexico City Federal District are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico City Federal District?

  • How old do you have to be to fly from Des Moines Airport to Mexico City Federal District?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The necessary travel and health documents for your Mexico City Federal District trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico City Federal District

Compare and see reviews for airlines that fly from Des Moines to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
7.9
8,128 reviews
Search Delta flights
United AirlinesPriceFrom $379Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
American AirlinesPriceFrom $382Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico City Federal District?

Finding the right flight to Mexico City Federal District from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City Federal District quick and easy, saving you time and money.

Can I find flights from Des Moines to Mexico City Federal District with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico City Federal District from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico City Federal District?

momondo helps you find the best flight between Des Moines and Mexico City Federal District by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico City Federal District right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Mexico City Federal District flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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