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Cheap flights from Des Moines to Mexico City Federal District from $177

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico City Federal District departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Mexico City Federal District

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:30 pm - 10:00 pm
DSM
-
MEX
29h 30m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$392Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
4:30 pm - 8:50 pm
DSM
-
MEX
28h 20m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$394Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
4:30 pm - 8:50 pm
DSM
-
MEX
28h 20m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$406Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
4:30 pm - 8:50 pm
DSM
-
MEX
28h 20m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$412Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
4:30 pm - 8:50 pm
DSM
-
MEX
28h 20m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$414Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
4:30 pm - 8:25 pm
DSM
-
MEX
27h 55m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$416Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
8:30 am - 8:05 pm
DSM
-
MEX
11h 35m1 stop
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$430Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
2:58 pm - 10:00 pm
DSM
-
MEX
31h 02m2 stops
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$432Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
8:30 am - 9:10 pm
DSM
-
MEX
12h 40m1 stop
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$439Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
8:30 am - 9:10 pm
DSM
-
MEX
12h 40m1 stop
Multiple Airlines Logo
10:10 am - 10:09 pm
MEX
-
DSM
11h 59m1 stop
$441Multiple Airlines
Thu, Jan 22 - Thu, Jan 29

American Airlines flights from Des Moines to Mexico City Federal District

Our best American Airlines deals on Des Moines to Mexico City Federal District flight tickets
American Airlines
Dec 12
DSM3:38 pmDes Moines
6h 17m
1 stop
MEX9:55 pmMexico City Benito Juarez
Dec 31
MEX6:00 amMexico City Benito Juarez
8h 58m
1 stop
DSM2:58 pmDes Moines
$610
Find similar
American Airlines
Dec 13
DSM5:00 amDes Moines
6h 30m
1 stop
MEX11:30 amMexico City Benito Juarez
Jan 24
MEX8:00 amMexico City Benito Juarez
9h 06m
1 stop
DSM5:06 pmDes Moines
$675
Find similar
American Airlines
Dec 13
DSM5:21 amDes Moines
18h 49m
1 stop
MEX12:10 amMexico City Benito Juarez
Jan 24
MEX8:00 amMexico City Benito Juarez
15h 23m
1 stop
DSM11:23 pmDes Moines
$691
Find similar

United Airlines flights from Des Moines to Mexico City Federal District

Our best United Airlines deals on Des Moines to Mexico City Federal District flight tickets
United Airlines
Dec 12
DSM9:00 amDes Moines
15h 10m
2 stops
MEX12:10 amMexico City Benito Juarez
Dec 31
MEX5:45 amMexico City Benito Juarez
14h 45m
2 stops
DSM8:30 pmDes Moines
$706
Find similar
United Airlines
Dec 25
DSM5:30 amDes Moines
17h 00m
1 stop
MEX10:30 pmMexico City Benito Juarez
Jan 4
MEX9:05 amMexico City Benito Juarez
7h 20m
1 stop
DSM4:25 pmDes Moines
$713
Find similar
United Airlines
Dec 13
DSM1:31 pmDes Moines
10h 39m
2 stops
MEX12:10 amMexico City Benito Juarez
Jan 24
MEX10:05 amMexico City Benito Juarez
10h 29m
2 stops
DSM8:34 pmDes Moines
$718
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

4:30 pm-10:00 pm

2 stops29h 30m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$392

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

4:30 pm-8:50 pm

2 stops28h 20m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$394

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

4:30 pm-8:50 pm

2 stops28h 20m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$406

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

4:30 pm-8:50 pm

2 stops28h 20m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$412

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

4:30 pm-8:50 pm

2 stops28h 20m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$414

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 1/18

4:30 pm-8:25 pm

2 stops27h 55m

Mexico City Benito Juarez

Sun 1/25

10:10 am-10:09 pm

1 stop11h 59m

$416

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 1/18

8:30 am-8:05 pm

1 stop11h 35m

Mexico City Benito Juarez

Sun 1/25

10:10 am-10:09 pm

1 stop11h 59m

$430

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

2:58 pm-10:00 pm

2 stops31h 02m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$432

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

8:30 am-9:10 pm

1 stop12h 40m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$439

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/22

8:30 am-9:10 pm

1 stop12h 40m

Mexico City Benito Juarez

Thu 1/29

10:10 am-10:09 pm

1 stop11h 59m

$441

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Des Moines to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of August, then departing from Des Moines during the month February is also very affordable. Most momondo users find prices during this month for around $549.

What is the cheapest day to depart on your flight to Mexico City Federal District?

The cheapest day to depart on your flight to Mexico City Federal District is on a Thursday when prices can be found for as low as $610. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Mexico City Federal District for around $864.

What is the cheapest time of day to depart on your flight to Mexico City Federal District?

The cheapest time of day to fly to Mexico City Federal District is in the morning when flights can be purchased for as low as $692. At noon is when there is more demand to fly to Mexico City Federal District, so prices are often more expensive at around $822 per ticket.

Cheap Des Moines to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico City Federal District

Fastest flight time

6h 10m

Direct flights

None
The fastest flight from Des Moines to Mexico City Federal District takes 6h 10m
There are no direct flights from Des Moines to Mexico City Federal District. There are no popular flight routes from Des Moines to Mexico City Federal District.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico City Federal District?

    Prices for flights from Des Moines Airport to Mexico City Federal District are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico City Federal District?

  • How old do you have to be to fly from Des Moines Airport to Mexico City Federal District?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The necessary travel and health documents for your Mexico City Federal District trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico City Federal District

Compare and see reviews for airlines that fly from Des Moines to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $379Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
American AirlinesPriceFrom $420Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico City Federal District?

Finding the right flight to Mexico City Federal District from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City Federal District quick and easy, saving you time and money.

Can I find flights from Des Moines to Mexico City Federal District with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico City Federal District from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico City Federal District?

momondo helps you find the best flight between Des Moines and Mexico City Federal District by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico City Federal District right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Mexico City Federal District flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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