What is the cheapest airline that flies from Des Moines to Italy?

American Airlines, Air Canada, and British Airways are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of August 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$516 Cheap Flights from Des Moines to Italy in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:05 am - 7:30 amDSM Des Moines-MXP Milan Malpensa

18h 25m2 stops Chicago O'Hare Intl Newark

12:55 pm - 10:32 amMXP Milan Malpensa-DSM Des Moines

28h 37m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$723United Airlines

Mon, Nov 16 - Fri, Nov 20

6:45 pm - 1:15 pmDSM Des Moines-MXP Milan Malpensa

11h 30m1 stop Chicago O'Hare Intl

12:55 pm - 10:32 amMXP Milan Malpensa-DSM Des Moines

28h 37m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$723United Airlines

Mon, Nov 16 - Fri, Nov 20

3:24 pm - 1:15 pmDSM Des Moines-MXP Milan Malpensa

14h 51m1 stop Chicago O'Hare Intl

3:15 pm - 10:50 pmMXP Milan Malpensa-DSM Des Moines

14h 35m1 stop Chicago O'Hare Intl

$743United Airlines

Mon, Nov 16 - Fri, Nov 20

5:45 am - 10:20 amDSM Des Moines-MXP Milan Malpensa

21h 35m2 stops Denver Intl Montreal Pierre Elliott Trudeau Intl

12:20 pm - 11:48 pmMXP Milan Malpensa-DSM Des Moines

42h 28m2 stops Montreal Pierre Elliott Trudeau Intl Denver Intl

$745Air Canada

Tue, Oct 13 - Wed, Oct 21

9:15 am - 10:20 amDSM Des Moines-MXP Milan Malpensa

18h 05m2 stops Denver Intl Montreal Pierre Elliott Trudeau Intl

12:20 pm - 10:31 amMXP Milan Malpensa-DSM Des Moines

29h 11m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$745Air Canada

Tue, Oct 13 - Wed, Oct 21

11:27 am - 10:20 amDSM Des Moines-MXP Milan Malpensa

15h 53m3 stops Chicago O'Hare Intl Toronto Island Montreal Pierre Elliott Trudeau Intl

12:20 pm - 10:31 amMXP Milan Malpensa-DSM Des Moines

29h 11m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$745Multiple Airlines

Tue, Oct 13 - Wed, Oct 21

11:30 am - 12:20 pmDSM Des Moines-LIN Milan Linate

17h 50m2 stops Chicago O'Hare Intl Brussels Bruxelles-National

6:25 am - 11:01 pmLIN Milan Linate-DSM Des Moines

23h 36m2 stops Frankfurt am Main Chicago O'Hare Intl

$756United Airlines

Mon, Feb 1 - Fri, Feb 5

2:58 pm - 7:50 pmDSM Des Moines-FLR Florence Peretola

21h 52m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle

1:05 pm - 4:49 pmFLR Florence Peretola-DSM Des Moines

34h 44m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County

$781Delta

Mon, Nov 16 - Thu, Nov 26

11:00 am - 2:25 pmDSM Des Moines-FLR Florence Peretola

20h 25m2 stops Minneapolis St Paul Paris Charles de Gaulle

6:40 am - 9:13 pmFLR Florence Peretola-DSM Des Moines

21h 33m2 stops Amsterdam Schiphol Minneapolis St Paul

$781Delta

Wed, Nov 18 - Wed, Nov 25

10:21 am - 2:25 pmDSM Des Moines-FLR Florence Peretola

21h 04m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

1:05 pm - 4:49 pmFLR Florence Peretola-DSM Des Moines

34h 44m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County

$781Delta

Sun, Nov 15 - Thu, Nov 26

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United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Nov 16

DSM6:45 pmDes Moines

11h 30m

1 stop

MXP1:15 pmMilan Malpensa

Nov 20

MXP12:55 pmMilan Malpensa

28h 37m

2 stops

DSM10:32 amDes Moines

$723

United Airlines

Nov 16

DSM3:24 pmDes Moines

14h 51m

1 stop

MXP1:15 pmMilan Malpensa

Nov 20

MXP3:15 pmMilan Malpensa

14h 35m

1 stop

DSM10:50 pmDes Moines

$743

United Airlines

Feb 1

DSM11:30 amDes Moines

17h 50m

2 stops

LIN12:20 pmMilan Linate

Feb 5

LIN6:25 amMilan Linate

23h 36m

2 stops

DSM11:01 pmDes Moines

$756

Lufthansa flights from Des Moines to Italy

Our best Lufthansa deals on Des Moines to Italy flight tickets

Lufthansa

Nov 16

DSM6:45 pmDes Moines

18h 30m

2 stops

FLR8:15 pmFlorence Peretola

Nov 25

FLR10:20 amFlorence Peretola

19h 30m

2 stops

DSM10:50 pmDes Moines

$768

Lufthansa

Nov 15

DSM6:45 pmDes Moines

18h 30m

2 stops

FLR8:15 pmFlorence Peretola

Nov 24

FLR6:30 amFlorence Peretola

22h 55m

2 stops

DSM10:25 pmDes Moines

$769

Lufthansa

Nov 15

DSM6:45 pmDes Moines

14h 35m

2 stops

FLR4:20 pmFlorence Peretola

Nov 23

FLR5:00 pmFlorence Peretola

36h 25m

2 stops

DSM10:25 pmDes Moines

$800

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 11/16

6:05 am-7:30 am

2 stops18h 25m

Milan Malpensa

Fri 11/20

12:55 pm-10:32 am

2 stops28h 37m

$723

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 11/16

6:45 pm-1:15 pm

1 stop11h 30m

Milan Malpensa

Fri 11/20

12:55 pm-10:32 am

2 stops28h 37m

$723

Quickest round-trip

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 11/16

3:24 pm-1:15 pm

1 stop14h 51m

Milan Malpensa

Fri 11/20

3:15 pm-10:50 pm

1 stop14h 35m

$743

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Tue 10/13

5:45 am-10:20 am

2 stops21h 35m

Milan Malpensa

Wed 10/21

12:20 pm-11:48 pm

2 stops42h 28m

$745

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Tue 10/13

9:15 am-10:20 am

2 stops18h 05m

Milan Malpensa

Wed 10/21

12:20 pm-10:31 am

2 stops29h 11m

$745

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Tue 10/13

11:27 am-10:20 am

3 stops15h 53m

Milan Malpensa

Wed 10/21

12:20 pm-10:31 am

2 stops29h 11m

$745

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Mon 2/1

11:30 am-12:20 pm

2 stops17h 50m

Milan Linate

Fri 2/5

6:25 am-11:01 pm

2 stops23h 36m

$756

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Mon 11/16

2:58 pm-7:50 pm

2 stops21h 52m

Florence Peretola

Thu 11/26

1:05 pm-4:49 pm

2 stops34h 44m

$781

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Wed 11/18

11:00 am-2:25 pm

2 stops20h 25m

Florence Peretola

Wed 11/25

6:40 am-9:13 pm

2 stops21h 33m

$781

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Sun 11/15

10:21 am-2:25 pm

2 stops21h 04m

Florence Peretola

Thu 11/26

1:05 pm-4:49 pm

2 stops34h 44m

$781

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $712, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during February instead. Flights to Italy in February, while not as cheap as those in November, still average around $741.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 44% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Best Price Found	$516
Fastest flight time	13h 05m
Direct flights	None

The best one-way flight to Italy from Des Moines in the past 72 hours is $516. The best round-trip flight deal from Des Moines to Italy found on momondo in the last 72 hours is $723.

The fastest flight from Des Moines to Italy takes 13h 05m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of August 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 10,112 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.8 8,517 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.