What is the cheapest airline that flies from Des Moines to Italy?

American Airlines, KLM, and United Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of July 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$344 Cheap Flights from Des Moines to Italy in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:55 pm - 10:20 am

DSM

MXP

32h 25m

3 stops

12:55 pm - 4:09 pm

MXP

DSM

34h 14m

3 stops

$722Air Canada

Sat, Oct 17 - Fri, Nov 13

6:45 pm - 10:05 am

DSM

MXP

56h 20m

2 stops

12:55 pm - 9:21 pm

MXP

DSM

39h 26m

2 stops

$731Air Canada

Fri, Dec 11 - Wed, Dec 16

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

11:20 am - 11:40 pm

MXP

DSM

19h 20m

2 stops

$744United Airlines

Tue, Dec 1 - Wed, Dec 9

6:21 am - 7:30 am

DSM

MXP

18h 09m

2 stops

10:30 am - 11:01 pm

MXP

DSM

43h 31m

2 stops

$747United Airlines

Sun, Nov 29 - Wed, Dec 2

10:15 am - 1:55 pm

DSM

LIN

20h 40m

2 stops

6:30 am - 9:24 pm

LIN

DSM

21h 54m

2 stops

$753Delta

Tue, Dec 1 - Wed, Dec 9

6:15 am - 7:55 am

DSM

FCO

18h 40m

2 stops

1:15 pm - 11:40 pm

FCO

DSM

41h 25m

2 stops

$770Multiple Airlines

Tue, Dec 1 - Wed, Dec 9

6:45 pm - 6:15 pm

DSM

FCO

16h 30m

2 stops

1:30 pm - 11:01 pm

FCO

DSM

16h 31m

2 stops

$782Lufthansa

Wed, Dec 9 - Wed, Dec 16

10:55 am - 10:15 am

DSM

FCO

16h 20m

1 stop

10:00 am - 4:50 pm

FCO

DSM

13h 50m

1 stop

$790Delta

Tue, Dec 1 - Wed, Dec 9

8:00 am - 7:55 am

DSM

FCO

40h 55m

3 stops

1:15 pm - 11:40 pm

FCO

DSM

41h 25m

2 stops

$791Multiple Airlines

Tue, Dec 1 - Wed, Dec 9

6:55 pm - 5:45 pm

DSM

LIN

15h 50m

2 stops

10:35 am - 11:35 pm

LIN

DSM

20h 00m

2 stops

$798Lufthansa

Tue, Oct 6 - Wed, Oct 14

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Iberia flights from Des Moines to Italy

Our best Iberia deals on Des Moines to Italy flight tickets

Iberia

Oct 3

DSM5:57 pmDes Moines

42h 08m

2 stops

VCE7:05 pmVenice Marco Polo

Oct 16

VCE6:25 amVenice Marco Polo

24h 39m

2 stops

DSM12:04 amDes Moines

$942

Iberia

Oct 5

DSM9:26 amDes Moines

16h 44m

1 stop

FCO9:10 amRome Fiumicino

Oct 26

FCO4:20 pmRome Fiumicino

32h 49m

2 stops

DSM7:09 pmDes Moines

$944

Iberia

Oct 3

DSM5:57 pmDes Moines

42h 08m

2 stops

VCE7:05 pmVenice Marco Polo

Oct 17

VCE6:25 amVenice Marco Polo

24h 39m

2 stops

DSM12:04 amDes Moines

$946

Lufthansa flights from Des Moines to Italy

Our best Lufthansa deals on Des Moines to Italy flight tickets

Lufthansa

Dec 9

DSM6:45 pmDes Moines

16h 30m

2 stops

FCO6:15 pmRome Fiumicino

Dec 16

FCO1:30 pmRome Fiumicino

16h 31m

2 stops

DSM11:01 pmDes Moines

$782

Lufthansa

Oct 6

DSM6:55 pmDes Moines

15h 50m

2 stops

LIN5:45 pmMilan Linate

Oct 14

LIN10:35 amMilan Linate

20h 00m

2 stops

DSM11:35 pmDes Moines

$798

Lufthansa

Dec 11

DSM8:15 pmDes Moines

14h 55m

2 stops

LIN6:10 pmMilan Linate

Dec 16

LIN1:40 pmMilan Linate

16h 21m

2 stops

DSM11:01 pmDes Moines

$803

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sat 10/17

6:55 pm-10:20 am

3 stops32h 25m

Milan Malpensa

Fri 11/13

12:55 pm-4:09 pm

3 stops34h 14m

$722

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 12/11

6:45 pm-10:05 am

2 stops56h 20m

Milan Malpensa

Wed 12/16

12:55 pm-9:21 pm

2 stops39h 26m

$731

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 12/1

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Wed 12/9

11:20 am-11:40 pm

2 stops19h 20m

$744

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/29

6:21 am-7:30 am

2 stops18h 09m

Milan Malpensa

Wed 12/2

10:30 am-11:01 pm

2 stops43h 31m

$747

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 12/1

10:15 am-1:55 pm

2 stops20h 40m

Milan Linate

Wed 12/9

6:30 am-9:24 pm

2 stops21h 54m

$753

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 12/1

6:15 am-7:55 am

2 stops18h 40m

Rome Fiumicino

Wed 12/9

1:15 pm-11:40 pm

2 stops41h 25m

$770

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 12/9

6:45 pm-6:15 pm

2 stops16h 30m

Rome Fiumicino

Wed 12/16

1:30 pm-11:01 pm

2 stops16h 31m

$782

Quickest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 12/1

10:55 am-10:15 am

1 stop16h 20m

Rome Fiumicino

Wed 12/9

10:00 am-4:50 pm

1 stop13h 50m

$790

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 12/1

8:00 am-7:55 am

3 stops40h 55m

Rome Fiumicino

Wed 12/9

1:15 pm-11:40 pm

2 stops41h 25m

$791

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 10/6

6:55 pm-5:45 pm

2 stops15h 50m

Milan Linate

Wed 10/14

10:35 am-11:35 pm

2 stops20h 00m

$798

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $712, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during February instead. Flights to Italy in February, while not as cheap as those in November, still average around $741.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 43% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	11h 34m
Direct flights	None

The fastest flight from Des Moines to Italy takes 11h 34m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of July 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 10,024 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.8 8,479 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.