What is the cheapest airline that flies from Des Moines to Italy?

Air Canada, United Airlines, and Delta are the most popular carriers operating from Des Moines to Italy

What airlines fly to Italy?

United Airlines, Delta and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. United Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 3 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 3 as of February 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$263 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:10 pm - 10:20 am

DSM

MXP

14h 10m

2 stops

12:20 pm - 11:02 pm

MXP

DSM

17h 42m

2 stops

$437Air Canada

Wed, Apr 8 - Wed, Apr 15

5:00 am - 1:20 pm

DSM

MXP

25h 20m

1 stop

9:00 am - 10:20 am

MXP

DSM

32h 20m

2 stops

$495United Airlines

Sat, Aug 1 - Sat, Aug 29

6:30 pm - 9:25 am

DSM

MXP

31h 55m

1 stop

11:40 am - 10:26 pm

MXP

DSM

17h 46m

1 stop

$498KLM

Sat, Aug 1 - Sat, Aug 29

2:15 pm - 11:00 pm

DSM

MXP

25h 45m

2 stops

6:45 am - 10:26 pm

MXP

DSM

22h 41m

2 stops

$508Delta

Sat, Aug 1 - Sat, Aug 29

5:47 pm - 1:55 pm

DSM

LIN

13h 08m

2 stops

11:00 am - 8:39 pm

LIN

DSM

16h 39m

2 stops

$539Delta

Wed, Apr 8 - Wed, Apr 15

8:03 pm - 10:20 pm

DSM

FLR

43h 17m

2 stops

7:05 am - 11:49 pm

FLR

DSM

23h 44m

2 stops

$593British Airways

Wed, Apr 15 - Wed, Apr 22

2:35 pm - 12:35 pm

DSM

FCO

15h 00m

1 stop

9:45 am - 5:42 pm

FCO

DSM

14h 57m

1 stop

$707KLM

Tue, Aug 11 - Thu, Aug 20

8:03 pm - 7:25 pm

DSM

VCE

16h 22m

2 stops

12:15 pm - 11:49 pm

VCE

DSM

18h 34m

2 stops

$740American Airlines

Wed, Apr 8 - Wed, Apr 15

8:03 pm - 7:25 pm

DSM

VCE

16h 22m

2 stops

12:15 pm - 10:18 pm

VCE

DSM

17h 03m

2 stops

$747American Airlines

Wed, Apr 8 - Wed, Apr 15

2:16 pm - 10:20 pm

DSM

FLR

25h 04m

2 stops

7:05 am - 11:49 pm

FLR

DSM

23h 44m

2 stops

$786British Airways

Wed, Apr 15 - Wed, Apr 22

Scandinavian Airlines flights from Des Moines to Italy

Our best Scandinavian Airlines deals on Des Moines to Italy flight tickets

Scandinavian Airlines

Aug 17

DSM2:15 pmDes Moines

37h 50m

2 stops

FCO11:05 amRome Fiumicino

Dec 15

FCO11:55 amRome Fiumicino

41h 34m

2 stops

DSM10:29 pmDes Moines

$625

Scandinavian Airlines

Aug 14

DSM2:15 pmDes Moines

37h 50m

2 stops

FCO11:05 amRome Fiumicino

Aug 22

FCO11:55 amRome Fiumicino

41h 31m

2 stops

DSM10:26 pmDes Moines

$655

KLM flights from Des Moines to Italy

Our best KLM deals on Des Moines to Italy flight tickets

KLM

Mar 2

DSM5:24 amDes Moines

20h 41m

1 stop

MXP9:05 amMilan Malpensa

Mar 17

MXP10:05 amMilan Malpensa

18h 33m

1 stop

DSM10:38 pmDes Moines

$493

KLM

Mar 2

DSM5:24 amDes Moines

20h 41m

1 stop

MXP9:05 amMilan Malpensa

Mar 10

MXP10:05 amMilan Malpensa

18h 33m

1 stop

DSM10:38 pmDes Moines

$501

KLM

Aug 11

DSM2:35 pmDes Moines

15h 00m

1 stop

FCO12:35 pmRome Fiumicino

Aug 20

FCO9:45 amRome Fiumicino

14h 57m

1 stop

DSM5:42 pmDes Moines

$707

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 4/8

1:10 pm-10:20 am

2 stops14h 10m

Milan Malpensa

Wed 4/15

12:20 pm-11:02 pm

2 stops17h 42m

$437

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sat 8/1

5:00 am-1:20 pm

1 stop25h 20m

Milan Malpensa

Sat 8/29

9:00 am-10:20 am

2 stops32h 20m

$495

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sat 8/1

6:30 pm-9:25 am

1 stop31h 55m

Milan Malpensa

Sat 8/29

11:40 am-10:26 pm

1 stop17h 46m

$498

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sat 8/1

2:15 pm-11:00 pm

2 stops25h 45m

Milan Malpensa

Sat 8/29

6:45 am-10:26 pm

2 stops22h 41m

$508

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Wed 4/8

5:47 pm-1:55 pm

2 stops13h 08m

Milan Linate

Wed 4/15

11:00 am-8:39 pm

2 stops16h 39m

$539

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

8:03 pm-10:20 pm

2 stops43h 17m

Florence Peretola

Wed 4/22

7:05 am-11:49 pm

2 stops23h 44m

$593

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

2:35 pm-12:35 pm

1 stop15h 00m

Rome Fiumicino

Thu 8/20

9:45 am-5:42 pm

1 stop14h 57m

$707

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Wed 4/8

8:03 pm-7:25 pm

2 stops16h 22m

Venice Marco Polo

Wed 4/15

12:15 pm-11:49 pm

2 stops18h 34m

$740

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Wed 4/8

8:03 pm-7:25 pm

2 stops16h 22m

Venice Marco Polo

Wed 4/15

12:15 pm-10:18 pm

2 stops17h 03m

$747

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

2:16 pm-10:20 pm

2 stops25h 04m

Florence Peretola

Wed 4/22

7:05 am-11:49 pm

2 stops23h 44m

$786

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $616, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during December instead. Flights to Italy in December, while not as cheap as those in November, still average around $689.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 9% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 00m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 00m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 3 as of February 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
KLM	PriceFrom $457	Free Cancellation	Rating 7.7 1,458 reviews	Search KLM flights
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,342 reviews	Search United Airlines flights
Delta	PriceFrom $505	Free Cancellation	Rating 7.9 8,235 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.