What is the cheapest airline that flies from Des Moines to Italy?

Lufthansa, KLM, and United Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of May 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$364 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:45 pm - 10:05 am

DSM

MXP

32h 20m

2 stops

1:05 pm - 12:40 am

MXP

DSM

42h 35m

2 stops

$726Air Canada

Sun, Nov 22 - Wed, Dec 16

8:15 pm - 10:05 am

DSM

MXP

30h 50m

3 stops

1:05 pm - 7:25 pm

MXP

DSM

37h 20m

2 stops

$731Air Canada

Sun, Nov 22 - Wed, Dec 16

11:30 am - 1:05 pm

DSM

MXP

18h 35m

1 stop

3:05 pm - 9:17 pm

MXP

DSM

13h 12m

1 stop

$743United Airlines

Sun, Nov 15 - Thu, Nov 19

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

11:20 am - 12:40 am

MXP

DSM

20h 20m

2 stops

$745United Airlines

Sun, Nov 15 - Thu, Nov 19

5:30 pm - 5:25 pm

DSM

MXP

16h 55m

2 stops

1:05 pm - 10:29 pm

MXP

DSM

16h 24m

1 stop

$747Delta

Sun, Nov 22 - Thu, Dec 17

6:30 pm - 11:10 am

DSM

MXP

33h 40m

1 stop

1:05 pm - 10:29 pm

MXP

DSM

16h 24m

1 stop

$748Delta

Sun, Nov 22 - Thu, Dec 17

6:00 am - 10:20 am

DSM

MXP

21h 20m

2 stops

12:20 pm - 2:15 pm

MXP

DSM

32h 55m

2 stops

$750Air Canada

Tue, Oct 13 - Wed, Oct 21

11:04 am - 6:45 pm

DSM

FCO

24h 41m

2 stops

11:55 am - 10:29 pm

FCO

DSM

41h 34m

2 stops

$780Scandinavian Airlines

Sun, Nov 22 - Tue, Dec 1

3:15 pm - 5:45 pm

DSM

FCO

20h 30m

2 stops

7:05 am - 9:17 pm

FCO

DSM

21h 12m

2 stops

$797Lufthansa

Sun, Oct 25 - Tue, Nov 10

8:15 pm - 7:45 am

DSM

FCO

28h 30m

1 stop

1:30 pm - 11:01 pm

FCO

DSM

16h 31m

2 stops

$799Lufthansa

Sun, Nov 22 - Tue, Dec 15

American Airlines flights from Des Moines to Italy

Our best American Airlines deals on Des Moines to Italy flight tickets

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 42m

2 stops

MXP1:25 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$763

American Airlines

Oct 6

DSM2:37 pmDes Moines

17h 23m

2 stops

LIN3:00 pmMilan Linate

Oct 14

LIN11:40 amMilan Linate

19h 15m

2 stops

DSM11:55 pmDes Moines

$798

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 47m

2 stops

LIN1:30 pmMilan Linate

Oct 27

LIN7:55 amMilan Linate

18h 16m

2 stops

DSM8:11 pmDes Moines

$846

Air France flights from Des Moines to Italy

Our best Air France deals on Des Moines to Italy flight tickets

Air France

Sep 2

DSM5:30 pmDes Moines

14h 15m

2 stops

MXP2:45 pmMilan Malpensa

Sep 21

MXP6:45 amMilan Malpensa

16h 56m

2 stops

DSM4:41 pmDes Moines

$866

Air France

Jul 8

DSM5:52 pmDes Moines

16h 23m

2 stops

FLR5:15 pmFlorence Peretola

Jul 15

FLR6:25 amFlorence Peretola

18h 27m

2 stops

DSM5:52 pmDes Moines

$974

Air France

Jul 6

DSM5:34 pmDes Moines

17h 16m

2 stops

VCE5:50 pmVenice Marco Polo

Jul 13

VCE9:10 pmVenice Marco Polo

26h 42m

2 stops

DSM4:52 pmDes Moines

$989

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/22

6:45 pm-10:05 am

2 stops32h 20m

Milan Malpensa

Wed 12/16

1:05 pm-12:40 am

2 stops42h 35m

$726

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/22

8:15 pm-10:05 am

3 stops30h 50m

Milan Malpensa

Wed 12/16

1:05 pm-7:25 pm

2 stops37h 20m

$731

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/15

11:30 am-1:05 pm

1 stop18h 35m

Milan Malpensa

Thu 11/19

3:05 pm-9:17 pm

1 stop13h 12m

$743

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/15

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Thu 11/19

11:20 am-12:40 am

2 stops20h 20m

$745

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/22

5:30 pm-5:25 pm

2 stops16h 55m

Milan Malpensa

Thu 12/17

1:05 pm-10:29 pm

1 stop16h 24m

$747

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/22

6:30 pm-11:10 am

1 stop33h 40m

Milan Malpensa

Thu 12/17

1:05 pm-10:29 pm

1 stop16h 24m

$748

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:00 am-10:20 am

2 stops21h 20m

Milan Malpensa

Wed 10/21

12:20 pm-2:15 pm

2 stops32h 55m

$750

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 11/22

11:04 am-6:45 pm

2 stops24h 41m

Rome Fiumicino

Tue 12/1

11:55 am-10:29 pm

2 stops41h 34m

$780

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 10/25

3:15 pm-5:45 pm

2 stops20h 30m

Rome Fiumicino

Tue 11/10

7:05 am-9:17 pm

2 stops21h 12m

$797

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 11/22

8:15 pm-7:45 am

1 stop28h 30m

Rome Fiumicino

Tue 12/15

1:30 pm-11:01 pm

2 stops16h 31m

$799

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	11h 37m
Direct flights	None

The fastest flight from Des Moines to Italy takes 11h 37m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of May 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,750 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.9 8,423 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.