What is the cheapest airline that flies from Des Moines to Italy?

Lufthansa, Air Canada, and United Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of March 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$306 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:16 pm - 4:40 pm

DSM

MXP

14h 24m

2 stops

2:50 pm - 11:17 pm

MXP

DSM

15h 27m

2 stops

$600Lufthansa

Wed, Apr 15 - Wed, Apr 22

7:16 pm - 5:45 pm

DSM

LIN

15h 29m

2 stops

1:40 pm - 9:32 pm

LIN

DSM

14h 52m

2 stops

$604Lufthansa

Wed, Apr 15 - Wed, Apr 22

6:10 am - 2:45 pm

DSM

MXP

25h 35m

2 stops

11:40 am - 1:55 pm

MXP

DSM

33h 15m

1 stop

$621Delta

Wed, Apr 15 - Wed, Apr 22

5:45 am - 6:45 am

DSM

MXP

18h 00m

2 stops

11:40 am - 10:34 pm

MXP

DSM

17h 54m

1 stop

$651Delta

Thu, Apr 23 - Wed, Apr 29

5:00 am - 9:10 am

DSM

FCO

21h 10m

1 stop

12:15 pm - 11:55 pm

FCO

DSM

18h 40m

1 stop

$691American Airlines

Tue, Aug 11 - Thu, Aug 20

9:00 am - 7:05 am

DSM

FCO

15h 05m

2 stops

12:15 pm - 11:55 pm

FCO

DSM

18h 40m

1 stop

$695American Airlines

Tue, Aug 11 - Thu, Aug 20

3:20 pm - 12:20 pm

DSM

LIN

14h 00m

2 stops

6:20 am - 3:48 pm

LIN

DSM

16h 28m

2 stops

$696United Airlines

Tue, May 12 - Fri, May 22

6:00 am - 7:35 am

DSM

FCO

18h 35m

2 stops

11:30 am - 2:05 pm

FCO

DSM

33h 35m

2 stops

$756United Airlines

Tue, Aug 11 - Thu, Aug 20

5:45 am - 8:55 am

DSM

VCE

20h 10m

1 stop

11:45 am - 8:39 pm

VCE

DSM

15h 54m

2 stops

$854KLM

Thu, Apr 23 - Thu, Apr 30

11:51 am - 8:55 am

DSM

VCE

14h 04m

1 stop

11:45 am - 8:39 pm

VCE

DSM

15h 54m

2 stops

$858KLM

Thu, Apr 23 - Thu, Apr 30

Iberia flights from Des Moines to Italy

Our best Iberia deals on Des Moines to Italy flight tickets

Iberia

Apr 22

DSM12:00 pmDes Moines

24h 35m

2 stops

FLR7:35 pmFlorence Peretola

Apr 29

FLR6:45 amFlorence Peretola

19h 48m

2 stops

DSM7:33 pmDes Moines

$842

Iberia

Apr 7

DSM8:03 pmDes Moines

20h 47m

2 stops

VCE11:50 pmVenice Marco Polo

Apr 14

VCE7:55 pmVenice Marco Polo

34h 54m

2 stops

DSM11:49 pmDes Moines

$845

Iberia

Apr 27

DSM2:16 pmDes Moines

11h 54m

1 stop

FCO9:10 amRome Fiumicino

May 4

FCO8:25 pmRome Fiumicino

30h 08m

2 stops

DSM7:33 pmDes Moines

$888

KLM flights from Des Moines to Italy

Our best KLM deals on Des Moines to Italy flight tickets

KLM

Apr 27

DSM5:45 pmDes Moines

15h 10m

2 stops

LIN3:55 pmMilan Linate

May 4

LIN6:40 amMilan Linate

16h 01m

2 stops

DSM3:41 pmDes Moines

$745

KLM

Apr 26

DSM11:51 amDes Moines

14h 34m

1 stop

MXP9:25 amMilan Malpensa

May 3

MXP11:40 amMilan Malpensa

17h 54m

1 stop

DSM10:34 pmDes Moines

$766

KLM

Apr 23

DSM11:51 amDes Moines

14h 04m

1 stop

VCE8:55 amVenice Marco Polo

Apr 30

VCE11:45 amVenice Marco Polo

15h 54m

2 stops

DSM8:39 pmDes Moines

$858

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 4/15

7:16 pm-4:40 pm

2 stops14h 24m

Milan Malpensa

Wed 4/22

2:50 pm-11:17 pm

2 stops15h 27m

$600

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Wed 4/15

7:16 pm-5:45 pm

2 stops15h 29m

Milan Linate

Wed 4/22

1:40 pm-9:32 pm

2 stops14h 52m

$604

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 4/15

6:10 am-2:45 pm

2 stops25h 35m

Milan Malpensa

Wed 4/22

11:40 am-1:55 pm

1 stop33h 15m

$621

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 4/23

5:45 am-6:45 am

2 stops18h 00m

Milan Malpensa

Wed 4/29

11:40 am-10:34 pm

1 stop17h 54m

$651

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

5:00 am-9:10 am

1 stop21h 10m

Rome Fiumicino

Thu 8/20

12:15 pm-11:55 pm

1 stop18h 40m

$691

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

9:00 am-7:05 am

2 stops15h 05m

Rome Fiumicino

Thu 8/20

12:15 pm-11:55 pm

1 stop18h 40m

$695

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 5/12

3:20 pm-12:20 pm

2 stops14h 00m

Milan Linate

Fri 5/22

6:20 am-3:48 pm

2 stops16h 28m

$696

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

6:00 am-7:35 am

2 stops18h 35m

Rome Fiumicino

Thu 8/20

11:30 am-2:05 pm

2 stops33h 35m

$756

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Thu 4/23

5:45 am-8:55 am

1 stop20h 10m

Venice Marco Polo

Thu 4/30

11:45 am-8:39 pm

2 stops15h 54m

$854

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Thu 4/23

11:51 am-8:55 am

1 stop14h 04m

Venice Marco Polo

Thu 4/30

11:45 am-8:39 pm

2 stops15h 54m

$858

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $616, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during December instead. Flights to Italy in December, while not as cheap as those in November, still average around $689.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 9% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 10m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 10m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of March 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,418 reviews		Search United Airlines flights
Delta	PriceFrom $505	Free Cancellation	Rating 7.9 8,288 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.