What is the cheapest airline that flies from Des Moines to Italy?

British Airways, United Airlines, and American Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of June 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$306 Cheap Flights from Des Moines to Italy in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:15 pm - 10:05 am

DSM

MXP

54h 50m

3 stops

12:55 pm - 11:40 pm

MXP

DSM

41h 45m

2 stops

$735Air Canada

Fri, Dec 11 - Wed, Dec 16

8:15 pm - 10:05 am

DSM

MXP

54h 50m

3 stops

12:55 pm - 11:40 pm

MXP

DSM

41h 45m

2 stops

$736Air Canada

Fri, Dec 11 - Wed, Dec 16

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

11:20 am - 10:30 pm

MXP

DSM

18h 10m

2 stops

$745United Airlines

Tue, Dec 1 - Thu, Dec 3

8:00 am - 7:30 am

DSM

MXP

16h 30m

3 stops

9:45 am - 11:39 pm

MXP

DSM

20h 54m

2 stops

$747United Airlines

Tue, Dec 1 - Thu, Dec 3

1:43 pm - 1:25 pm

DSM

MXP

16h 42m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$762American Airlines

Tue, Oct 13 - Wed, Oct 21

1:43 pm - 1:25 pm

DSM

MXP

16h 42m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$763American Airlines

Tue, Oct 13 - Wed, Oct 21

2:15 pm - 10:50 am

DSM

FCO

13h 35m

1 stop

9:00 am - 8:52 pm

FCO

DSM

18h 52m

1 stop

$792Delta

Tue, Oct 13 - Thu, Oct 22

5:35 pm - 7:45 pm

DSM

LIN

19h 10m

2 stops

6:40 am - 2:11 pm

LIN

DSM

14h 31m

2 stops

$801Delta

Wed, Sep 30 - Wed, Oct 7

10:23 am - 11:20 am

DSM

VCE

17h 57m

2 stops

9:10 pm - 5:11 pm

VCE

DSM

27h 01m

2 stops

$890Air France

Tue, Aug 11 - Tue, Aug 18

5:56 pm - 2:25 pm

DSM

FLR

13h 29m

2 stops

11:20 am - 8:59 pm

FLR

DSM

16h 39m

2 stops

$947Air France

Fri, Aug 7 - Fri, Aug 14

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American Airlines flights from Des Moines to Italy

Our best American Airlines deals on Des Moines to Italy flight tickets

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 42m

2 stops

MXP1:25 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$762

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 42m

2 stops

MXP1:25 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$763

American Airlines

Oct 13

DSM6:00 amDes Moines

21h 05m

1 stop

MXP10:05 amMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$766

Delta flights from Des Moines to Italy

Our best Delta deals on Des Moines to Italy flight tickets

Delta

Oct 13

DSM2:15 pmDes Moines

13h 35m

1 stop

FCO10:50 amRome Fiumicino

Oct 22

FCO9:00 amRome Fiumicino

18h 52m

1 stop

DSM8:52 pmDes Moines

$792

Delta

Sep 28

DSM5:35 pmDes Moines

14h 10m

2 stops

MXP2:45 pmMilan Malpensa

Oct 6

MXP11:40 amMilan Malpensa

17h 49m

1 stop

DSM10:29 pmDes Moines

$794

Delta

Oct 4

DSM8:43 amDes Moines

17h 42m

2 stops

MXP9:25 amMilan Malpensa

Oct 6

MXP11:35 amMilan Malpensa

16h 17m

2 stops

DSM8:52 pmDes Moines

$795

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 12/11

8:15 pm-10:05 am

3 stops54h 50m

Milan Malpensa

Wed 12/16

12:55 pm-11:40 pm

2 stops41h 45m

$735

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 12/11

8:15 pm-10:05 am

3 stops54h 50m

Milan Malpensa

Wed 12/16

12:55 pm-11:40 pm

2 stops41h 45m

$736

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 12/1

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Thu 12/3

11:20 am-10:30 pm

2 stops18h 10m

$745

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 12/1

8:00 am-7:30 am

3 stops16h 30m

Milan Malpensa

Thu 12/3

9:45 am-11:39 pm

2 stops20h 54m

$747

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

1:43 pm-1:25 pm

2 stops16h 42m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$762

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

1:43 pm-1:25 pm

2 stops16h 42m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$763

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/13

2:15 pm-10:50 am

1 stop13h 35m

Rome Fiumicino

Thu 10/22

9:00 am-8:52 pm

1 stop18h 52m

$792

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Wed 9/30

5:35 pm-7:45 pm

2 stops19h 10m

Milan Linate

Wed 10/7

6:40 am-2:11 pm

2 stops14h 31m

$801

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Tue 8/11

10:23 am-11:20 am

2 stops17h 57m

Venice Marco Polo

Tue 8/18

9:10 pm-5:11 pm

2 stops27h 01m

$890

Quickest round-trip

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 8/7

5:56 pm-2:25 pm

2 stops13h 29m

Florence Peretola

Fri 8/14

11:20 am-8:59 pm

2 stops16h 39m

$947

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 49m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 49m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of June 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,896 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.8 8,451 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.