What is the cheapest airline that flies from Des Moines to Italy?

British Airways, United Airlines, and Delta are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of May 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$350 Cheap Flights from Des Moines to Italy in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:45 am - 10:20 am

DSM

MXP

21h 35m

2 stops

12:20 pm - 11:01 pm

MXP

DSM

41h 41m

2 stops

$751Air Canada

Tue, Oct 13 - Wed, Oct 21

8:15 pm - 1:20 pm

DSM

MXP

34h 05m

1 stop

12:20 pm - 5:33 pm

MXP

DSM

36h 13m

2 stops

$753United Airlines

Tue, Oct 13 - Wed, Oct 21

6:36 pm - 5:50 pm

DSM

MXP

16h 14m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$764American Airlines

Tue, Oct 13 - Wed, Oct 21

11:04 am - 9:25 am

DSM

MXP

15h 21m

1 stop

11:40 am - 10:29 pm

MXP

DSM

17h 49m

1 stop

$767KLM

Tue, Oct 13 - Wed, Oct 21

6:36 pm - 5:50 pm

DSM

MXP

16h 14m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$788American Airlines

Tue, Oct 6 - Wed, Oct 14

6:45 pm - 4:40 pm

DSM

MXP

14h 55m

2 stops

2:50 pm - 11:01 pm

MXP

DSM

15h 11m

2 stops

$789Lufthansa

Tue, Oct 6 - Wed, Oct 14

11:04 am - 10:50 am

DSM

FCO

16h 46m

1 stop

9:45 am - 10:26 pm

FCO

DSM

19h 41m

1 stop

$791KLM

Tue, Aug 11 - Thu, Aug 20

6:45 pm - 5:45 pm

DSM

LIN

16h 00m

2 stops

12:40 pm - 11:01 pm

LIN

DSM

17h 21m

2 stops

$793Lufthansa

Tue, Oct 6 - Wed, Oct 14

2:15 pm - 1:55 pm

DSM

LIN

16h 40m

2 stops

6:40 am - 9:17 pm

LIN

DSM

21h 37m

2 stops

$803Delta

Sun, Aug 30 - Fri, Sep 25

2:35 pm - 1:55 pm

DSM

LIN

16h 20m

2 stops

6:40 am - 8:45 pm

LIN

DSM

21h 05m

2 stops

$863Delta

Sun, Aug 30 - Sun, Sep 20

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KLM flights from Des Moines to Italy

Our best KLM deals on Des Moines to Italy flight tickets

KLM

Oct 13

DSM11:04 amDes Moines

15h 21m

1 stop

MXP9:25 amMilan Malpensa

Oct 21

MXP11:40 amMilan Malpensa

17h 49m

1 stop

DSM10:29 pmDes Moines

$767

KLM

Aug 11

DSM11:04 amDes Moines

16h 46m

1 stop

FCO10:50 amRome Fiumicino

Aug 20

FCO9:45 amRome Fiumicino

19h 41m

1 stop

DSM10:26 pmDes Moines

$791

KLM

Oct 13

DSM2:15 pmDes Moines

12h 10m

1 stop

MXP9:25 amMilan Malpensa

Oct 27

MXP1:05 pmMilan Malpensa

15h 24m

1 stop

DSM10:29 pmDes Moines

$839

United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Aug 11

DSM6:00 amDes Moines

18h 55m

1 stop

FCO7:55 amRome Fiumicino

Aug 20

FCO11:30 amRome Fiumicino

33h 35m

2 stops

DSM2:05 pmDes Moines

$771

United Airlines

Aug 11

DSM11:23 amDes Moines

14h 52m

2 stops

FCO9:15 amRome Fiumicino

Aug 20

FCO11:30 amRome Fiumicino

33h 35m

2 stops

DSM2:05 pmDes Moines

$774

United Airlines

Aug 11

DSM1:05 pmDes Moines

11h 50m

1 stop

FCO7:55 amRome Fiumicino

Aug 20

FCO2:20 pmRome Fiumicino

30h 45m

2 stops

DSM2:05 pmDes Moines

$776

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

5:45 am-10:20 am

2 stops21h 35m

Milan Malpensa

Wed 10/21

12:20 pm-11:01 pm

2 stops41h 41m

$751

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

8:15 pm-1:20 pm

1 stop34h 05m

Milan Malpensa

Wed 10/21

12:20 pm-5:33 pm

2 stops36h 13m

$753

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:36 pm-5:50 pm

2 stops16h 14m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$764

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

11:04 am-9:25 am

1 stop15h 21m

Milan Malpensa

Wed 10/21

11:40 am-10:29 pm

1 stop17h 49m

$767

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/6

6:36 pm-5:50 pm

2 stops16h 14m

Milan Malpensa

Wed 10/14

2:20 pm-11:55 pm

1 stop16h 35m

$788

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/6

6:45 pm-4:40 pm

2 stops14h 55m

Milan Malpensa

Wed 10/14

2:50 pm-11:01 pm

2 stops15h 11m

$789

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

11:04 am-10:50 am

1 stop16h 46m

Rome Fiumicino

Thu 8/20

9:45 am-10:26 pm

1 stop19h 41m

$791

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 10/6

6:45 pm-5:45 pm

2 stops16h 00m

Milan Linate

Wed 10/14

12:40 pm-11:01 pm

2 stops17h 21m

$793

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Sun 8/30

2:15 pm-1:55 pm

2 stops16h 40m

Milan Linate

Fri 9/25

6:40 am-9:17 pm

2 stops21h 37m

$803

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Sun 8/30

2:35 pm-1:55 pm

2 stops16h 20m

Milan Linate

Sun 9/20

6:40 am-8:45 pm

2 stops21h 05m

$863

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 52m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 52m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of May 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,675 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.9 8,464 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.