What is the cheapest airline that flies from Des Moines to Italy?

United Airlines, Air Canada, and American Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of August 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$394 Cheap Flights from Des Moines to Italy in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 7:30 amDSM Des Moines-MXP Milan Malpensa

18h 15m2 stops Chicago O'Hare Intl Newark

12:55 pm - 7:25 pmMXP Milan Malpensa-DSM Des Moines

37h 30m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$723United Airlines

Mon, Dec 7 - Fri, Dec 11

6:45 pm - 10:05 amDSM Des Moines-MXP Milan Malpensa

56h 20m3 stops Chicago O'Hare Intl Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

12:55 pm - 9:21 pmMXP Milan Malpensa-DSM Des Moines

39h 26m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$736Air Canada

Fri, Dec 11 - Wed, Dec 16

8:15 pm - 10:05 amDSM Des Moines-MXP Milan Malpensa

54h 50m3 stops Chicago O'Hare Intl Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

12:55 pm - 9:21 pmMXP Milan Malpensa-DSM Des Moines

39h 26m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$736Air Canada

Fri, Dec 11 - Wed, Dec 16

8:15 pm - 10:05 amDSM Des Moines-MXP Milan Malpensa

54h 50m3 stops Chicago O'Hare Intl Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

12:55 pm - 9:21 pmMXP Milan Malpensa-DSM Des Moines

39h 26m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Chicago O'Hare Intl

$741Air Canada

Fri, Dec 11 - Wed, Dec 16

3:15 pm - 12:20 pmDSM Des Moines-LIN Milan Linate

14h 05m2 stops Chicago O'Hare Intl Brussels Bruxelles-National

6:25 am - 8:32 pmLIN Milan Linate-DSM Des Moines

21h 07m2 stops Frankfurt am Main Denver Intl

$756United Airlines

Mon, Dec 7 - Wed, Dec 9

9:27 am - 10:40 amDSM Des Moines-MXP Milan Malpensa

18h 13m2 stops Chicago O'Hare Intl Frankfurt am Main

12:55 pm - 2:11 pmMXP Milan Malpensa-DSM Des Moines

32h 16m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$761United Airlines

Sun, Dec 27 - Fri, Jan 8

9:27 am - 10:40 amDSM Des Moines-MXP Milan Malpensa

18h 13m2 stops Chicago O'Hare Intl Frankfurt am Main

12:55 pm - 2:11 pmMXP Milan Malpensa-DSM Des Moines

32h 16m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$761United Airlines

Sun, Dec 27 - Wed, Jan 6

11:31 am - 8:50 amDSM Des Moines-LIN Milan Linate

14h 19m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle

1:00 pm - 6:09 pmLIN Milan Linate-DSM Des Moines

36h 09m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson

$795Delta

Mon, Sep 21 - Tue, Oct 6

10:57 am - 1:55 pmDSM Des Moines-LIN Milan Linate

19h 58m2 stops Minneapolis St Paul Paris Charles de Gaulle

6:40 am - 9:02 pmLIN Milan Linate-DSM Des Moines

21h 22m2 stops Amsterdam Schiphol Minneapolis St Paul

$803Delta

Tue, Oct 6 - Wed, Oct 14

11:04 am - 11:20 amDSM Des Moines-FCO Rome Fiumicino

17h 16m1 stop Atlanta Hartsfield-Jackson

6:10 am - 8:52 pmFCO Rome Fiumicino-DSM Des Moines

21h 42m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County

$839Delta

Wed, Jan 27 - Sat, Feb 6

Cheap last minute flights

Enter your travel dates to find the best prices.

8:00 am - 7:55 amDSM Des Moines-FCO Rome Fiumicino

16h 55m1 stop Chicago O'Hare Intl

11:30 am - 12:20 pmFCO Rome Fiumicino-DSM Des Moines

31h 50m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$954United Airlines

Tue, Aug 11 - Thu, Aug 20

8:00 am - 11:45 amDSM Des Moines-FCO Rome Fiumicino

20h 45m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

11:30 am - 2:16 pmFCO Rome Fiumicino-DSM Des Moines

33h 46m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$957Air Canada

Tue, Aug 11 - Thu, Aug 20

11:32 am - 7:55 amDSM Des Moines-FCO Rome Fiumicino

13h 23m1 stop Chicago O'Hare Intl

2:20 pm - 10:26 amFCO Rome Fiumicino-DSM Des Moines

27h 06m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$959United Airlines

Tue, Aug 11 - Thu, Aug 20

1:35 pm - 12:20 pmDSM Des Moines-FCO Rome Fiumicino

15h 45m1 stop Denver Intl

12:25 pm - 12:20 pmFCO Rome Fiumicino-DSM Des Moines

30h 55m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$959United Airlines

Tue, Aug 11 - Thu, Aug 20

6:00 am - 8:15 amDSM Des Moines-FCO Rome Fiumicino

19h 15m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

12:25 pm - 10:26 amFCO Rome Fiumicino-DSM Des Moines

29h 01m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$959United Airlines

Tue, Aug 11 - Thu, Aug 20

8:00 am - 11:45 amDSM Des Moines-FCO Rome Fiumicino

20h 45m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

2:20 pm - 12:20 pmFCO Rome Fiumicino-DSM Des Moines

29h 00m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$962Air Canada

Tue, Aug 11 - Thu, Aug 20

11:32 am - 9:15 amDSM Des Moines-FCO Rome Fiumicino

14h 43m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

12:25 pm - 9:23 pmFCO Rome Fiumicino-DSM Des Moines

39h 58m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$962Air Canada

Tue, Aug 11 - Thu, Aug 20

10:26 am - 9:10 amDSM Des Moines-FCO Rome Fiumicino

15h 44m1 stop Chicago O'Hare Intl

10:00 am - 7:19 pmFCO Rome Fiumicino-DSM Des Moines

16h 19m1 stop Chicago O'Hare Intl

$964British Airways

Tue, Aug 11 - Thu, Aug 20

11:32 am - 11:45 amDSM Des Moines-FCO Rome Fiumicino

17h 13m3 stops Chicago O'Hare Intl Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

2:20 pm - 12:20 pmFCO Rome Fiumicino-DSM Des Moines

29h 00m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$970Multiple Airlines

Tue, Aug 11 - Thu, Aug 20

6:00 am - 11:00 amDSM Des Moines-FCO Rome Fiumicino

22h 00m1 stop Detroit Metropolitan Wayne County

1:10 pm - 10:37 pmFCO Rome Fiumicino-DSM Des Moines

16h 27m1 stop Atlanta Hartsfield-Jackson

$974Delta

Tue, Aug 11 - Thu, Aug 20

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Air France flights from Des Moines to Italy

Our best Air France deals on Des Moines to Italy flight tickets

Air France

Sep 22

DSM5:59 pmDes Moines

13h 26m

2 stops

FCO2:25 pmRome Fiumicino

Sep 29

FCO9:00 amRome Fiumicino

15h 19m

1 stop

DSM5:19 pmDes Moines

$976

Air France

Sep 21

DSM5:59 pmDes Moines

18h 41m

2 stops

FLR7:40 pmFlorence Peretola

Sep 28

FLR8:35 pmFlorence Peretola

27h 44m

2 stops

DSM5:19 pmDes Moines

$981

Air France

Sep 21

DSM11:31 amDes Moines

14h 24m

1 stop

VCE8:55 amVenice Marco Polo

Sep 28

VCE6:55 pmVenice Marco Polo

29h 24m

2 stops

DSM5:19 pmDes Moines

$1,012

United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Dec 7

DSM6:15 amDes Moines

18h 15m

2 stops

MXP7:30 amMilan Malpensa

Dec 11

MXP12:55 pmMilan Malpensa

37h 30m

2 stops

DSM7:25 pmDes Moines

$723

United Airlines

Dec 7

DSM3:15 pmDes Moines

14h 05m

2 stops

LIN12:20 pmMilan Linate

Dec 9

LIN6:25 amMilan Linate

21h 07m

2 stops

DSM8:32 pmDes Moines

$756

United Airlines

Dec 27

DSM9:27 amDes Moines

18h 13m

2 stops

MXP10:40 amMilan Malpensa

Jan 6

MXP12:55 pmMilan Malpensa

32h 16m

2 stops

DSM2:11 pmDes Moines

$761

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 12/7

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Fri 12/11

12:55 pm-7:25 pm

2 stops37h 30m

$723

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Fri 12/11

6:45 pm-10:05 am

3 stops56h 20m

Milan Malpensa

Wed 12/16

12:55 pm-9:21 pm

2 stops39h 26m

$736

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Fri 12/11

8:15 pm-10:05 am

3 stops54h 50m

Milan Malpensa

Wed 12/16

12:55 pm-9:21 pm

2 stops39h 26m

$736

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Fri 12/11

8:15 pm-10:05 am

3 stops54h 50m

Milan Malpensa

Wed 12/16

12:55 pm-9:21 pm

3 stops39h 26m

$741

Quickest round-trip

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Mon 12/7

3:15 pm-12:20 pm

2 stops14h 05m

Milan Linate

Wed 12/9

6:25 am-8:32 pm

2 stops21h 07m

$756

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Sun 12/27

9:27 am-10:40 am

2 stops18h 13m

Milan Malpensa

Fri 1/8

12:55 pm-2:11 pm

2 stops32h 16m

$761

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Sun 12/27

9:27 am-10:40 am

2 stops18h 13m

Milan Malpensa

Wed 1/6

12:55 pm-2:11 pm

2 stops32h 16m

$761

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Mon 9/21

11:31 am-8:50 am

2 stops14h 19m

Milan Linate

Tue 10/6

1:00 pm-6:09 pm

2 stops36h 09m

$795

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Tue 10/6

10:57 am-1:55 pm

2 stops19h 58m

Milan Linate

Wed 10/14

6:40 am-9:02 pm

2 stops21h 22m

$803

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Wed 1/27

11:04 am-11:20 am

1 stop17h 16m

Rome Fiumicino

Sat 2/6

6:10 am-8:52 pm

2 stops21h 42m

$839

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $712, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during February instead. Flights to Italy in February, while not as cheap as those in November, still average around $741.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 44% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	13h 36m
Direct flights	None

The fastest flight from Des Moines to Italy takes 13h 36m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of August 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 10,086 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.8 8,504 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.