What is the cheapest airline that flies from Des Moines to Italy?

Delta, United Airlines, and KLM are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of October 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$336 Cheap Flights from Des Moines to Italy in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 pm - 4:20 pmDSM Des Moines-FLR Florence Peretola

14h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:30 am - 5:33 pmFLR Florence Peretola-DSM Des Moines

17h 03m2 stops Frankfurt am Main Chicago O'Hare Intl

$734Lufthansa

Tue, Mar 9 - Tue, Mar 16

7:00 pm - 8:15 pmDSM Des Moines-FLR Florence Peretola

18h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:30 am - 10:56 pmFLR Florence Peretola-DSM Des Moines

22h 26m2 stops Frankfurt am Main Chicago O'Hare Intl

$734Lufthansa

Tue, Mar 9 - Wed, Mar 17

8:00 am - 8:55 amDSM Des Moines-FCO Rome Fiumicino

17h 55m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:15 pm - 9:15 pmFCO Rome Fiumicino-DSM Des Moines

39h 00m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$737Air Canada

Sun, Jan 31 - Wed, Feb 17

6:30 pm - 8:55 amDSM Des Moines-FCO Rome Fiumicino

31h 25m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:15 pm - 11:28 pmFCO Rome Fiumicino-DSM Des Moines

41h 13m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$737Air Canada

Sat, Feb 6 - Wed, Feb 17

8:00 am - 10:05 amDSM Des Moines-MXP Milan Malpensa

19h 05m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Montreal Pierre Elliott Trudeau Intl

11:20 am - 10:30 pmMXP Milan Malpensa-DSM Des Moines

18h 10m2 stops Frankfurt am Main Houston George Bush Intcntl

$743United Airlines

Mon, Feb 1 - Fri, Feb 5

6:20 am - 2:25 pmDSM Des Moines-FLR Florence Peretola

25h 05m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

1:05 pm - 8:00 pmFLR Florence Peretola-DSM Des Moines

36h 55m2 stops Amsterdam Schiphol New York John F Kennedy Intl

$744Delta

Mon, Mar 8 - Wed, Mar 17

7:25 am - 11:25 amDSM Des Moines-FLR Florence Peretola

21h 00m2 stops New York LaGuardia Paris Charles de Gaulle

6:40 am - 9:24 pmFLR Florence Peretola-DSM Des Moines

20h 44m2 stops Amsterdam Schiphol Minneapolis St Paul

$744Delta

Wed, Mar 3 - Tue, Mar 16

6:20 am - 7:50 pmDSM Des Moines-FLR Florence Peretola

30h 30m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

11:20 am - 4:50 pmFLR Florence Peretola-DSM Des Moines

35h 30m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County

$744Delta

Sun, Mar 7 - Mon, Mar 15

8:00 am - 1:50 pmDSM Des Moines-FLR Florence Peretola

22h 50m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Zurich

6:30 am - 10:56 pmFLR Florence Peretola-DSM Des Moines

22h 26m2 stops Frankfurt am Main Chicago O'Hare Intl

$745United Airlines

Tue, Mar 9 - Thu, Mar 18

8:00 am - 1:50 pmDSM Des Moines-FLR Florence Peretola

22h 50m2 stops Chicago O'Hare Intl Zurich

6:30 am - 9:17 pmFLR Florence Peretola-DSM Des Moines

20h 47m2 stops Frankfurt am Main Chicago O'Hare Intl

$745United Airlines

Tue, Mar 2 - Thu, Mar 18

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United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Feb 1

DSM8:00 amDes Moines

16h 55m

3 stops

FCO7:55 amRome Fiumicino

Feb 5

FCO1:15 pmRome Fiumicino

30h 02m

2 stops

DSM12:17 pmDes Moines

$738

United Airlines

Feb 1

DSM8:00 amDes Moines

16h 55m

2 stops

FCO7:55 amRome Fiumicino

Feb 5

FCO1:15 pmRome Fiumicino

28h 26m

2 stops

DSM10:41 amDes Moines

$739

United Airlines

Feb 1

DSM12:52 pmDes Moines

17h 23m

2 stops

FCO1:15 pmRome Fiumicino

Feb 12

FCO1:15 pmRome Fiumicino

32h 52m

2 stops

DSM3:07 pmDes Moines

$741

KLM flights from Des Moines to Italy

Our best KLM deals on Des Moines to Italy flight tickets

KLM

Dec 9

DSM5:20 amDes Moines

19h 55m

1 stop

FCO8:15 amRome Fiumicino

Feb 17

FCO6:10 amRome Fiumicino

22h 14m

2 stops

DSM9:24 pmDes Moines

$774

KLM

Nov 9

DSM10:24 amDes Moines

16h 11m

1 stop

FCO9:35 amRome Fiumicino

Nov 24

FCO10:00 amRome Fiumicino

13h 49m

1 stop

DSM4:49 pmDes Moines

$775

KLM

Feb 2

DSM5:45 amDes Moines

19h 30m

1 stop

FCO8:15 amRome Fiumicino

Feb 14

FCO6:10 amRome Fiumicino

16h 47m

2 stops

DSM3:57 pmDes Moines

$803

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Tue 3/9

7:00 pm-4:20 pm

2 stops14h 20m

Florence Peretola

Tue 3/16

6:30 am-5:33 pm

2 stops17h 03m

$734

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Tue 3/9

7:00 pm-8:15 pm

2 stops18h 15m

Florence Peretola

Wed 3/17

6:30 am-10:56 pm

2 stops22h 26m

$734

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sun 1/31

8:00 am-8:55 am

2 stops17h 55m

Rome Fiumicino

Wed 2/17

1:15 pm-9:15 pm

2 stops39h 00m

$737

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sat 2/6

6:30 pm-8:55 am

2 stops31h 25m

Rome Fiumicino

Wed 2/17

1:15 pm-11:28 pm

2 stops41h 13m

$737

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 2/1

8:00 am-10:05 am

3 stops19h 05m

Milan Malpensa

Fri 2/5

11:20 am-10:30 pm

2 stops18h 10m

$743

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Mon 3/8

6:20 am-2:25 pm

2 stops25h 05m

Florence Peretola

Wed 3/17

1:05 pm-8:00 pm

2 stops36h 55m

$744

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Wed 3/3

7:25 am-11:25 am

2 stops21h 00m

Florence Peretola

Tue 3/16

6:40 am-9:24 pm

2 stops20h 44m

$744

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Sun 3/7

6:20 am-7:50 pm

2 stops30h 30m

Florence Peretola

Mon 3/15

11:20 am-4:50 pm

2 stops35h 30m

$744

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Tue 3/9

8:00 am-1:50 pm

3 stops22h 50m

Florence Peretola

Thu 3/18

6:30 am-10:56 pm

2 stops22h 26m

$745

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Tue 3/2

8:00 am-1:50 pm

2 stops22h 50m

Florence Peretola

Thu 3/18

6:30 am-9:17 pm

2 stops20h 47m

$745

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in February. Flight prices, which tend to average around $716, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Italy from Des Moines during January instead. Flights to Italy in January, while not as cheap as those in February, still average around $840.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 43% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Best Price Found	$336
Fastest flight time	14h 10m
Direct flights	None

The best one-way flight to Italy from Des Moines in the past 72 hours is $336. The best round-trip flight deal from Des Moines to Italy found on momondo in the last 72 hours is $734.

The fastest flight from Des Moines to Italy takes 14h 10m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of October 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $910	Free Cancellation	Rating 7.8 8,652 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.