What is the cheapest airline that flies from Des Moines to Italy?

United Airlines, Lufthansa, and British Airways are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of October 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$349 Cheap Flights from Des Moines to Italy in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:24 am - 9:35 amDSM Des Moines-FCO Rome Fiumicino

16h 11m1 stop Detroit Metropolitan Wayne County

12:30 pm - 9:31 pmFCO Rome Fiumicino-DSM Des Moines

16h 01m1 stop Minneapolis St Paul

$676Multiple Airlines

Mon, Nov 23 - Fri, Dec 11

10:24 am - 8:45 amDSM Des Moines-FCO Rome Fiumicino

15h 21m2 stops Detroit Metropolitan Wayne County Boston Logan Intl

10:00 am - 4:49 pmFCO Rome Fiumicino-DSM Des Moines

13h 49m1 stop Detroit Metropolitan Wayne County

$681Air France

Mon, Nov 23 - Fri, Dec 11

5:30 am - 11:20 amDSM Des Moines-FCO Rome Fiumicino

22h 50m1 stop Atlanta Hartsfield-Jackson

12:30 pm - 9:31 pmFCO Rome Fiumicino-DSM Des Moines

16h 01m1 stop Minneapolis St Paul

$686Delta

Mon, Nov 23 - Fri, Dec 11

11:36 am - 9:35 amDSM Des Moines-FCO Rome Fiumicino

14h 59m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County

10:00 am - 9:31 pmFCO Rome Fiumicino-DSM Des Moines

18h 31m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul

$691Delta

Mon, Nov 23 - Fri, Dec 11

9:45 am - 10:45 amDSM Des Moines-FCO Rome Fiumicino

18h 00m1 stop Dallas/Fort Worth

1:10 pm - 12:33 amFCO Rome Fiumicino-DSM Des Moines

18h 23m2 stops Philadelphia Chicago O'Hare Intl

$691American Airlines

Mon, Nov 23 - Fri, Dec 11

2:58 pm - 10:45 amDSM Des Moines-MXP Milan Malpensa

12h 47m1 stop Atlanta Hartsfield-Jackson

6:30 pm - 4:11 pmMXP Milan Malpensa-DSM Des Moines

28h 41m2 stops Paris Charles de Gaulle Minneapolis St Paul

$708Multiple Airlines

Mon, Dec 7 - Mon, Dec 14

8:00 am - 1:50 pmDSM Des Moines-FLR Florence Peretola

22h 50m2 stops Chicago O'Hare Intl Zurich

6:30 am - 10:30 pmFLR Florence Peretola-DSM Des Moines

23h 00m2 stops Frankfurt am Main Houston George Bush Intcntl

$745United Airlines

Mon, Feb 1 - Fri, Feb 5

12:52 pm - 4:30 pmDSM Des Moines-MXP Milan Malpensa

20h 38m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

11:20 am - 10:30 pmMXP Milan Malpensa-DSM Des Moines

18h 10m2 stops Frankfurt am Main Houston George Bush Intcntl

$747United Airlines

Mon, Feb 1 - Fri, Feb 5

9:25 am - 12:20 pmDSM Des Moines-LIN Milan Linate

19h 55m2 stops Chicago O'Hare Intl Brussels Bruxelles-National

6:25 am - 9:23 pmLIN Milan Linate-DSM Des Moines

21h 58m2 stops Frankfurt am Main Chicago O'Hare Intl

$751United Airlines

Mon, Feb 1 - Fri, Feb 5

4:53 pm - 6:35 pmDSM Des Moines-LIN Milan Linate

18h 42m2 stops Minneapolis St Paul Amsterdam Schiphol

6:30 am - 10:38 pmLIN Milan Linate-DSM Des Moines

23h 08m2 stops Paris Charles de Gaulle Atlanta Hartsfield-Jackson

$779Delta

Fri, Dec 11 - Wed, Dec 16

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Air France flights from Des Moines to Italy

Our best Air France deals on Des Moines to Italy flight tickets

Air France

Nov 23

DSM10:24 amDes Moines

15h 21m

2 stops

FCO8:45 amRome Fiumicino

Dec 11

FCO10:00 amRome Fiumicino

13h 49m

1 stop

DSM4:49 pmDes Moines

$681

Air France

Dec 7

DSM2:58 pmDes Moines

12h 47m

1 stop

MXP10:45 amMilan Malpensa

Dec 14

MXP12:55 pmMilan Malpensa

16h 43m

1 stop

DSM10:38 pmDes Moines

$711

Air France

Dec 7

DSM2:58 pmDes Moines

12h 47m

1 stop

MXP10:45 amMilan Malpensa

Dec 14

MXP12:55 pmMilan Malpensa

16h 43m

1 stop

DSM10:38 pmDes Moines

$721

United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Nov 23

DSM8:00 amDes Moines

16h 55m

3 stops

FCO7:55 amRome Fiumicino

Dec 11

FCO1:30 pmRome Fiumicino

16h 36m

2 stops

DSM11:06 pmDes Moines

$733

United Airlines

Nov 23

DSM8:00 amDes Moines

16h 55m

3 stops

FCO7:55 amRome Fiumicino

Dec 11

FCO7:05 amRome Fiumicino

19h 14m

2 stops

DSM7:19 pmDes Moines

$738

United Airlines

Feb 1

DSM8:00 amDes Moines

22h 50m

2 stops

FLR1:50 pmFlorence Peretola

Feb 5

FLR6:30 amFlorence Peretola

23h 00m

2 stops

DSM10:30 pmDes Moines

$745

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Mon 11/23

10:24 am-9:35 am

1 stop16h 11m

Rome Fiumicino

Fri 12/11

12:30 pm-9:31 pm

1 stop16h 01m

$676

Quickest round-trip

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Mon 11/23

10:24 am-8:45 am

2 stops15h 21m

Rome Fiumicino

Fri 12/11

10:00 am-4:49 pm

1 stop13h 49m

$681

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Mon 11/23

5:30 am-11:20 am

1 stop22h 50m

Rome Fiumicino

Fri 12/11

12:30 pm-9:31 pm

1 stop16h 01m

$686

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Mon 11/23

11:36 am-9:35 am

2 stops14h 59m

Rome Fiumicino

Fri 12/11

10:00 am-9:31 pm

2 stops18h 31m

$691

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Mon 11/23

9:45 am-10:45 am

1 stop18h 00m

Rome Fiumicino

Fri 12/11

1:10 pm-12:33 am

2 stops18h 23m

$691

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 12/7

2:58 pm-10:45 am

1 stop12h 47m

Milan Malpensa

Mon 12/14

6:30 pm-4:11 pm

2 stops28h 41m

$708

Des MoinesFlorence

DSM Des Moines - FLR Florence Peretola

DSMFLR

Des Moines

Mon 2/1

8:00 am-1:50 pm

2 stops22h 50m

Florence Peretola

Fri 2/5

6:30 am-10:30 pm

2 stops23h 00m

$745

Des MoinesMilan

DSM Des Moines - MXP Milan Malpensa

DSMMXP

Des Moines

Mon 2/1

12:52 pm-4:30 pm

2 stops20h 38m

Milan Malpensa

Fri 2/5

11:20 am-10:30 pm

2 stops18h 10m

$747

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Mon 2/1

9:25 am-12:20 pm

2 stops19h 55m

Milan Linate

Fri 2/5

6:25 am-9:23 pm

2 stops21h 58m

$751

Des MoinesMilan

DSM Des Moines - LIN Milan Linate

DSMLIN

Des Moines

Fri 12/11

4:53 pm-6:35 pm

2 stops18h 42m

Milan Linate

Wed 12/16

6:30 am-10:38 pm

2 stops23h 08m

$779

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in February. Flight prices, which tend to average around $741, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Italy from Des Moines during January instead. Flights to Italy in January, while not as cheap as those in February, still average around $840.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 43% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Best Price Found	$349
Fastest flight time	13h 37m
Direct flights	None

The best one-way flight to Italy from Des Moines in the past 72 hours is $349. The best round-trip flight deal from Des Moines to Italy found on momondo in the last 72 hours is $676.

The fastest flight from Des Moines to Italy takes 13h 37m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of October 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $863	Free Cancellation	Rating 7.8 8,692 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.