What is the cheapest airline that flies from Des Moines to Italy?

United Airlines, Lufthansa, and Delta are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of June 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$424 Cheap Flights from Des Moines to Italy in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:45 pm - 1:05 pm

DSM

MXP

11h 20m

1 stop

3:05 pm - 9:17 pm

MXP

DSM

13h 12m

1 stop

$743United Airlines

Mon, Nov 16 - Thu, Nov 19

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

11:20 am - 11:01 pm

MXP

DSM

18h 41m

2 stops

$745United Airlines

Mon, Nov 16 - Thu, Nov 19

8:00 am - 7:30 am

DSM

MXP

16h 30m

3 stops

9:45 am - 10:30 pm

MXP

DSM

19h 45m

2 stops

$747United Airlines

Mon, Nov 16 - Thu, Nov 19

5:45 am - 10:20 am

DSM

MXP

21h 35m

2 stops

12:20 pm - 11:59 pm

MXP

DSM

42h 39m

2 stops

$750Air Canada

Tue, Oct 13 - Wed, Oct 21

8:00 am - 7:30 am

DSM

MXP

16h 30m

3 stops

1:05 pm - 5:33 pm

MXP

DSM

35h 28m

2 stops

$751Multiple Airlines

Wed, Nov 4 - Wed, Nov 11

6:00 am - 10:20 am

DSM

MXP

21h 20m

2 stops

12:20 pm - 12:34 pm

MXP

DSM

31h 14m

3 stops

$755Air Canada

Tue, Oct 13 - Wed, Oct 21

8:00 am - 7:30 am

DSM

MXP

16h 30m

3 stops

1:05 pm - 12:30 pm

MXP

DSM

30h 25m

3 stops

$756Multiple Airlines

Wed, Nov 4 - Wed, Nov 11

2:15 pm - 9:25 am

DSM

MXP

12h 10m

1 stop

11:40 am - 10:29 pm

MXP

DSM

17h 49m

1 stop

$767KLM

Tue, Oct 13 - Wed, Oct 21

5:45 am - 8:15 am

DSM

FCO

19h 30m

1 stop

10:00 am - 4:50 pm

FCO

DSM

13h 50m

1 stop

$790Delta

Mon, Nov 23 - Tue, Dec 15

6:30 pm - 8:15 am

DSM

FCO

30h 45m

1 stop

10:00 am - 4:50 pm

FCO

DSM

13h 50m

1 stop

$796Delta

Sun, Nov 22 - Tue, Dec 15

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British Airways flights from Des Moines to Italy

Our best British Airways deals on Des Moines to Italy flight tickets

British Airways

Aug 20

DSM1:55 pmDes Moines

17h 25m

2 stops

FCO2:20 pmRome Fiumicino

Aug 26

FCO10:00 amRome Fiumicino

16h 19m

1 stop

DSM7:19 pmDes Moines

$847

British Airways

Aug 20

DSM10:26 amDes Moines

15h 44m

1 stop

FCO9:10 amRome Fiumicino

Aug 26

FCO10:00 amRome Fiumicino

16h 19m

1 stop

DSM7:19 pmDes Moines

$856

British Airways

Jul 22

DSM1:04 pmDes Moines

13h 51m

1 stop

VCE9:55 amVenice Marco Polo

Jul 29

VCE12:15 pmVenice Marco Polo

18h 43m

1 stop

DSM11:58 pmDes Moines

$1,174

Lufthansa flights from Des Moines to Italy

Our best Lufthansa deals on Des Moines to Italy flight tickets

Lufthansa

Oct 6

DSM6:55 pmDes Moines

15h 50m

2 stops

LIN5:45 pmMilan Linate

Oct 14

LIN10:35 amMilan Linate

20h 00m

2 stops

DSM11:35 pmDes Moines

$793

Lufthansa

Oct 6

DSM6:55 pmDes Moines

15h 50m

2 stops

LIN5:45 pmMilan Linate

Oct 14

LIN12:40 pmMilan Linate

17h 55m

2 stops

DSM11:35 pmDes Moines

$794

Lufthansa

Nov 23

DSM6:45 pmDes Moines

16h 30m

2 stops

FCO6:15 pmRome Fiumicino

Dec 14

FCO7:05 pmRome Fiumicino

33h 12m

2 stops

DSM9:17 pmDes Moines

$813

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Mon 11/16

6:45 pm-1:05 pm

1 stop11h 20m

Milan Malpensa

Thu 11/19

3:05 pm-9:17 pm

1 stop13h 12m

$743

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Mon 11/16

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Thu 11/19

11:20 am-11:01 pm

2 stops18h 41m

$745

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Mon 11/16

8:00 am-7:30 am

3 stops16h 30m

Milan Malpensa

Thu 11/19

9:45 am-10:30 pm

2 stops19h 45m

$747

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

5:45 am-10:20 am

2 stops21h 35m

Milan Malpensa

Wed 10/21

12:20 pm-11:59 pm

2 stops42h 39m

$750

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 11/4

8:00 am-7:30 am

3 stops16h 30m

Milan Malpensa

Wed 11/11

1:05 pm-5:33 pm

2 stops35h 28m

$751

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:00 am-10:20 am

2 stops21h 20m

Milan Malpensa

Wed 10/21

12:20 pm-12:34 pm

3 stops31h 14m

$755

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 11/4

8:00 am-7:30 am

3 stops16h 30m

Milan Malpensa

Wed 11/11

1:05 pm-12:30 pm

3 stops30h 25m

$756

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

2:15 pm-9:25 am

1 stop12h 10m

Milan Malpensa

Wed 10/21

11:40 am-10:29 pm

1 stop17h 49m

$767

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 11/23

5:45 am-8:15 am

1 stop19h 30m

Rome Fiumicino

Tue 12/15

10:00 am-4:50 pm

1 stop13h 50m

$790

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 11/22

6:30 pm-8:15 am

1 stop30h 45m

Rome Fiumicino

Tue 12/15

10:00 am-4:50 pm

1 stop13h 50m

$796

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	14h 40m
Direct flights	None

The fastest flight from Des Moines to Italy takes 14h 40m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of June 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,804 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.9 8,396 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.