What is the cheapest airline that flies from Des Moines to Italy?

British Airways, KLM, and American Airlines are the most popular carriers operating from Des Moines to Italy

What airlines fly to Italy?

Delta, United Airlines and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 3 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 3 as of May 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$350 Cheap Flights from Des Moines to Italy in 2026

1 adult

0 bags

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

12:20 pm - 10:20 am

MXP

DSM

29h 00m

2 stops

$747United Airlines

Tue, Oct 13 - Wed, Oct 21

11:30 am - 10:20 am

DSM

MXP

15h 50m

3 stops

12:20 pm - 10:20 am

MXP

DSM

29h 00m

2 stops

$751Multiple Airlines

Tue, Oct 13 - Wed, Oct 21

8:00 am - 10:20 am

DSM

MXP

19h 20m

2 stops

12:20 pm - 12:40 am

MXP

DSM

43h 20m

3 stops

$755Air Canada

Tue, Oct 13 - Wed, Oct 21

6:36 pm - 5:50 pm

DSM

MXP

16h 14m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$764American Airlines

Tue, Oct 13 - Wed, Oct 21

2:15 pm - 9:25 am

DSM

MXP

12h 10m

1 stop

11:40 am - 10:29 pm

MXP

DSM

17h 49m

1 stop

$767KLM

Tue, Oct 13 - Wed, Oct 21

11:30 am - 10:20 am

DSM

MXP

15h 50m

3 stops

12:20 pm - 12:40 am

MXP

DSM

19h 20m

3 stops

$774Air Canada

Tue, Oct 13 - Wed, Oct 21

2:45 pm - 1:55 pm

DSM

LIN

16h 10m

2 stops

11:00 am - 8:45 pm

LIN

DSM

16h 45m

2 stops

$803Delta

Sun, Aug 30 - Tue, Sep 22

6:36 pm - 5:15 pm

DSM

LIN

15h 39m

2 stops

7:55 am - 8:11 pm

LIN

DSM

18h 16m

2 stops

$847American Airlines

Tue, Oct 13 - Tue, Oct 27

2:15 pm - 1:55 pm

DSM

LIN

16h 40m

2 stops

6:40 am - 8:45 pm

LIN

DSM

21h 05m

2 stops

$863Delta

Fri, Sep 4 - Thu, Sep 24

10:25 am - 11:00 am

DSM

FCO

17h 35m

1 stop

6:30 am - 2:05 pm

FCO

DSM

14h 35m

2 stops

$989KLM

Tue, Jul 7 - Fri, Jul 17

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Air France flights from Des Moines to Italy

Our best Air France deals on Des Moines to Italy flight tickets

Air France

Sep 2

DSM5:25 pmDes Moines

14h 20m

2 stops

MXP2:45 pmMilan Malpensa

Sep 22

MXP11:40 amMilan Malpensa

17h 46m

1 stop

DSM10:26 pmDes Moines

$1,070

Air France

Jun 17

DSM6:03 pmDes Moines

16h 57m

2 stops

VCE6:00 pmVenice Marco Polo

Jun 24

VCE5:55 amVenice Marco Polo

21h 46m

2 stops

DSM8:41 pmDes Moines

$1,103

American Airlines flights from Des Moines to Italy

Our best American Airlines deals on Des Moines to Italy flight tickets

American Airlines

Oct 13

DSM6:36 pmDes Moines

16h 14m

2 stops

MXP5:50 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$764

American Airlines

Oct 6

DSM6:00 amDes Moines

21h 05m

1 stop

MXP10:05 amMilan Malpensa

Oct 14

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$791

American Airlines

Oct 13

DSM6:36 pmDes Moines

16h 14m

2 stops

MXP5:50 pmMilan Malpensa

Oct 27

MXP2:20 pmMilan Malpensa

15h 35m

1 stop

DSM11:55 pmDes Moines

$836

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Wed 10/21

12:20 pm-10:20 am

2 stops29h 00m

$747

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

11:30 am-10:20 am

3 stops15h 50m

Milan Malpensa

Wed 10/21

12:20 pm-10:20 am

2 stops29h 00m

$751

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

8:00 am-10:20 am

2 stops19h 20m

Milan Malpensa

Wed 10/21

12:20 pm-12:40 am

3 stops43h 20m

$755

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:36 pm-5:50 pm

2 stops16h 14m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$764

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

2:15 pm-9:25 am

1 stop12h 10m

Milan Malpensa

Wed 10/21

11:40 am-10:29 pm

1 stop17h 49m

$767

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

11:30 am-10:20 am

3 stops15h 50m

Milan Malpensa

Wed 10/21

12:20 pm-12:40 am

3 stops19h 20m

$774

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Sun 8/30

2:45 pm-1:55 pm

2 stops16h 10m

Milan Linate

Tue 9/22

11:00 am-8:45 pm

2 stops16h 45m

$803

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 10/13

6:36 pm-5:15 pm

2 stops15h 39m

Milan Linate

Tue 10/27

7:55 am-8:11 pm

2 stops18h 16m

$847

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Fri 9/4

2:15 pm-1:55 pm

2 stops16h 40m

Milan Linate

Thu 9/24

6:40 am-8:45 pm

2 stops21h 05m

$863

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 7/7

10:25 am-11:00 am

1 stop17h 35m

Rome Fiumicino

Fri 7/17

6:30 am-2:05 pm

2 stops14h 35m

$989

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	11h 48m
Direct flights	None

The fastest flight from Des Moines to Italy takes 11h 48m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

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Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 3 as of May 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
KLM	PriceFrom $457	Free Cancellation	Rating 7.8 1,511 reviews	Search KLM flights
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,684 reviews	Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.9 8,459 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.