What is the cheapest airline that flies from Des Moines to Italy?

Delta, KLM, and United Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 2 as of September 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$288 Cheap Flights from Des Moines to Italy in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:35 am - 8:15 amDSM Des Moines-FCO Rome Fiumicino

20h 40m1 stop Atlanta Hartsfield-Jackson

10:00 am - 7:15 pmFCO Rome Fiumicino-DSM Des Moines

16h 15m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul

$587Multiple Airlines

Sun, Oct 25 - Tue, Nov 10

10:22 am - 9:35 amDSM Des Moines-FCO Rome Fiumicino

17h 13m1 stop Detroit Metropolitan Wayne County

10:25 am - 10:35 pmFCO Rome Fiumicino-DSM Des Moines

19h 10m1 stop Atlanta Hartsfield-Jackson

$587KLM

Sun, Oct 25 - Tue, Nov 10

10:57 am - 8:15 amDSM Des Moines-FCO Rome Fiumicino

15h 18m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

10:00 am - 7:15 pmFCO Rome Fiumicino-DSM Des Moines

16h 15m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul

$587Air France

Sun, Oct 25 - Tue, Nov 10

2:58 pm - 11:20 amDSM Des Moines-FCO Rome Fiumicino

13h 22m1 stop Atlanta Hartsfield-Jackson

1:30 pm - 10:38 pmFCO Rome Fiumicino-DSM Des Moines

16h 08m1 stop Atlanta Hartsfield-Jackson

$596Delta

Tue, Dec 1 - Wed, Dec 9

11:36 am - 11:20 amDSM Des Moines-FCO Rome Fiumicino

16h 44m1 stop Atlanta Hartsfield-Jackson

10:00 am - 4:49 pmFCO Rome Fiumicino-DSM Des Moines

13h 49m1 stop Detroit Metropolitan Wayne County

$596Air France

Wed, Nov 11 - Wed, Nov 18

11:04 am - 8:15 amDSM Des Moines-FCO Rome Fiumicino

14h 11m1 stop Atlanta Hartsfield-Jackson

1:30 pm - 10:29 pmFCO Rome Fiumicino-DSM Des Moines

15h 59m1 stop Atlanta Hartsfield-Jackson

$601Delta

Tue, Jan 12 - Tue, Jan 26

11:04 am - 8:15 amDSM Des Moines-FCO Rome Fiumicino

14h 11m1 stop Atlanta Hartsfield-Jackson

1:30 pm - 10:29 pmFCO Rome Fiumicino-DSM Des Moines

15h 59m1 stop Atlanta Hartsfield-Jackson

$601Delta

Tue, Jan 12 - Wed, Jan 20

9:30 am - 7:45 amDSM Des Moines-FCO Rome Fiumicino

15h 15m1 stop Chicago O'Hare Intl

1:15 pm - 2:19 pmFCO Rome Fiumicino-DSM Des Moines

32h 04m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$707United Airlines

Tue, Dec 1 - Wed, Dec 9

8:00 am - 7:45 amDSM Des Moines-FCO Rome Fiumicino

16h 45m1 stop Chicago O'Hare Intl

11:15 am - 10:30 pmFCO Rome Fiumicino-DSM Des Moines

42h 15m2 stops Toronto Pearson Intl Houston George Bush Intcntl

$712United Airlines

Sun, Nov 8 - Tue, Nov 17

1:45 pm - 1:15 pmDSM Des Moines-FCO Rome Fiumicino

16h 30m2 stops Denver Intl Munich Franz Josef Strauss

1:15 pm - 2:34 pmFCO Rome Fiumicino-DSM Des Moines

32h 19m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$720United Airlines

Thu, Jan 7 - Sun, Jan 24

Cheap last minute flights

Enter your travel dates to find the best prices.

10:59 am - 12:40 pmDSM Des Moines-FCO Rome Fiumicino

18h 41m1 stop Minneapolis St Paul

2:45 pm - 9:11 pmFCO Rome Fiumicino-DSM Des Moines

13h 26m1 stop Minneapolis St Paul

$695KLM

Mon, Sep 21 - Tue, Sep 29

11:31 am - 12:40 pmDSM Des Moines-FCO Rome Fiumicino

18h 09m1 stop Atlanta Hartsfield-Jackson

9:00 am - 8:46 pmFCO Rome Fiumicino-DSM Des Moines

18h 46m1 stop Detroit Metropolitan Wayne County

$695KLM

Sun, Sep 20 - Wed, Sep 30

6:00 am - 7:35 amDSM Des Moines-FCO Rome Fiumicino

18h 35m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

9:00 am - 8:46 pmFCO Rome Fiumicino-DSM Des Moines

18h 46m1 stop Detroit Metropolitan Wayne County

$700Delta

Sun, Sep 20 - Wed, Sep 30

6:00 am - 7:55 amDSM Des Moines-FCO Rome Fiumicino

18h 55m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl

10:10 am - 10:26 pmFCO Rome Fiumicino-DSM Des Moines

19h 16m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$700Delta

Mon, Sep 21 - Tue, Sep 29

2:46 pm - 12:40 pmDSM Des Moines-FCO Rome Fiumicino

14h 54m1 stop Minneapolis St Paul

10:10 am - 10:26 pmFCO Rome Fiumicino-DSM Des Moines

19h 16m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$700Delta

Mon, Sep 21 - Tue, Sep 29

3:22 pm - 9:15 amDSM Des Moines-FCO Rome Fiumicino

34h 53m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

11:30 am - 10:31 amFCO Rome Fiumicino-DSM Des Moines

30h 01m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$771Air Canada

Sun, Sep 20 - Wed, Sep 30

11:32 am - 11:45 amDSM Des Moines-FCO Rome Fiumicino

17h 13m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

11:30 am - 11:35 pmFCO Rome Fiumicino-DSM Des Moines

19h 05m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Chicago O'Hare Intl

$951Multiple Airlines

Sun, Sep 20 - Wed, Sep 30

11:33 am - 12:20 pmDSM Des Moines-FCO Rome Fiumicino

17h 47m1 stop Denver Intl

11:30 am - 12:34 pmFCO Rome Fiumicino-DSM Des Moines

32h 04m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$1,064United Airlines

Sun, Sep 20 - Tue, Sep 29

8:00 am - 1:15 pmDSM Des Moines-FCO Rome Fiumicino

22h 15m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:20 pm - 2:20 pmFCO Rome Fiumicino-DSM Des Moines

31h 00m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$1,194United Airlines

Fri, Sep 18 - Sun, Sep 20

8:00 am - 1:15 pmDSM Des Moines-FCO Rome Fiumicino

22h 15m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:20 pm - 11:33 pmFCO Rome Fiumicino-DSM Des Moines

16h 13m1 stop Denver Intl

$1,209United Airlines

Fri, Sep 18 - Sun, Sep 20

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Nov 8

DSM8:00 amDes Moines

16h 45m

1 stop

FCO7:45 amRome Fiumicino

Nov 17

FCO11:15 amRome Fiumicino

42h 15m

2 stops

DSM10:30 pmDes Moines

$712

United Airlines

Jan 7

DSM1:45 pmDes Moines

16h 30m

2 stops

FCO1:15 pmRome Fiumicino

Jan 24

FCO1:15 pmRome Fiumicino

32h 19m

2 stops

DSM2:34 pmDes Moines

$720

United Airlines

Oct 13

DSM3:11 pmDes Moines

15h 09m

1 stop

MXP1:20 pmMilan Malpensa

Oct 21

MXP12:20 pmMilan Malpensa

42h 15m

2 stops

DSM11:35 pmDes Moines

$722

American Airlines flights from Des Moines to Italy

Our best American Airlines deals on Des Moines to Italy flight tickets

American Airlines

Oct 29

DSM6:05 amDes Moines

20h 50m

1 stop

VCE8:55 amVenice Marco Polo

Nov 5

VCE6:20 amVenice Marco Polo

19h 36m

2 stops

DSM6:56 pmDes Moines

$909

American Airlines

Oct 31

DSM1:15 pmDes Moines

13h 40m

1 stop

VCE8:55 amVenice Marco Polo

Nov 7

VCE6:40 amVenice Marco Polo

19h 13m

2 stops

DSM6:53 pmDes Moines

$1,030

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sun 10/25

5:35 am-8:15 am

1 stop20h 40m

Rome Fiumicino

Tue 11/10

10:00 am-7:15 pm

2 stops16h 15m

$587

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sun 10/25

10:22 am-9:35 am

1 stop17h 13m

Rome Fiumicino

Tue 11/10

10:25 am-10:35 pm

1 stop19h 10m

$587

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sun 10/25

10:57 am-8:15 am

2 stops15h 18m

Rome Fiumicino

Tue 11/10

10:00 am-7:15 pm

2 stops16h 15m

$587

Quickest round-trip

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Tue 12/1

2:58 pm-11:20 am

1 stop13h 22m

Rome Fiumicino

Wed 12/9

1:30 pm-10:38 pm

1 stop16h 08m

$596

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Wed 11/11

11:36 am-11:20 am

1 stop16h 44m

Rome Fiumicino

Wed 11/18

10:00 am-4:49 pm

1 stop13h 49m

$596

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Tue 1/12

11:04 am-8:15 am

1 stop14h 11m

Rome Fiumicino

Tue 1/26

1:30 pm-10:29 pm

1 stop15h 59m

$601

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Tue 1/12

11:04 am-8:15 am

1 stop14h 11m

Rome Fiumicino

Wed 1/20

1:30 pm-10:29 pm

1 stop15h 59m

$601

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Tue 12/1

9:30 am-7:45 am

1 stop15h 15m

Rome Fiumicino

Wed 12/9

1:15 pm-2:19 pm

2 stops32h 04m

$707

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Sun 11/8

8:00 am-7:45 am

1 stop16h 45m

Rome Fiumicino

Tue 11/17

11:15 am-10:30 pm

2 stops42h 15m

$712

Des MoinesRome

DSM Des Moines - FCO Rome Fiumicino

DSMFCO

Des Moines

Thu 1/7

1:45 pm-1:15 pm

2 stops16h 30m

Rome Fiumicino

Sun 1/24

1:15 pm-2:34 pm

2 stops32h 19m

$720

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in February. Flight prices, which tend to average around $716, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Italy from Des Moines during January instead. Flights to Italy in January, while not as cheap as those in February, still average around $844.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 44% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Best Price Found	$288
Fastest flight time	13h 04m
Direct flights	None

The best one-way flight to Italy from Des Moines in the past 72 hours is $288. The best round-trip flight deal from Des Moines to Italy found on momondo in the last 72 hours is $587.

The fastest flight from Des Moines to Italy takes 13h 04m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 2 as of September 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 10,214 reviews		Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.8 8,581 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.