What airlines fly to Italy?

United Airlines, Delta and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 4 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Italy?

Lufthansa, Air Canada, and United Airlines are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 3 as of January 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$238 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:44 pm - 7:45 pm

DSM

MXP

18h 01m2 stops

8:50 pm - 11:40 pm

MXP

DSM

32h 50m2 stops

$442British Airways

Tue, Mar 10 - Mon, Mar 23

1:38 pm - 4:55 pm

DSM

VCE

20h 17m2 stops

8:35 pm - 11:40 pm

VCE

DSM

34h 05m2 stops

$444British Airways

Wed, Feb 18 - Wed, Feb 25

1:38 pm - 9:35 pm

DSM

LIN

25h 57m2 stops

4:35 pm - 11:40 pm

LIN

DSM

37h 05m2 stops

$445British Airways

Tue, Mar 10 - Mon, Mar 23

11:17 am - 12:25 pm

DSM

FCO

18h 08m2 stops

1:10 pm - 11:40 pm

FCO

DSM

17h 30m2 stops

$446American Airlines

Wed, Feb 18 - Wed, Feb 25

12:04 pm - 10:30 am

DSM

FCO

15h 26m1 stop

12:40 pm - 4:27 pm

FCO

DSM

34h 47m1 stop

$450KLM

Wed, Feb 18 - Wed, Feb 25

11:17 am - 12:25 pm

DSM

FCO

18h 08m2 stops

8:20 pm - 10:34 am

FCO

DSM

21h 14m2 stops

$454American Airlines

Wed, Feb 18 - Wed, Feb 25

5:15 pm - 9:05 am

DSM

MXP

32h 50m1 stop

11:05 am - 4:27 pm

MXP

DSM

36h 22m1 stop

$457KLM

Thu, Feb 19 - Thu, Feb 26

12:06 pm - 9:45 am

DSM

FCO

14h 39m2 stops

12:40 pm - 9:41 am

FCO

DSM

28h 01m2 stops

$462Delta

Tue, Feb 3 - Tue, Feb 10

6:55 pm - 9:55 am

DSM

MXP

32h 00m2 stops

1:05 pm - 2:27 pm

MXP

DSM

32h 22m2 stops

$475United Airlines

Wed, Feb 18 - Wed, Feb 25

2:59 pm - 2:15 pm

DSM

LIN

16h 16m2 stops

6:00 am - 9:41 pm

LIN

DSM

22h 41m2 stops

$519United Airlines

Thu, Feb 19 - Thu, Feb 26

British Airways flights from Des Moines to Italy

Our best British Airways deals on Des Moines to Italy flight tickets

British Airways

Mar 10

DSM7:44 pmDes Moines

18h 01m

2 stops

MXP7:45 pmMilan Malpensa

Mar 23

MXP8:50 pmMilan Malpensa

32h 50m

2 stops

DSM11:40 pmDes Moines

$442

Find similar

British Airways

Feb 18

DSM1:38 pmDes Moines

20h 17m

2 stops

VCE4:55 pmVenice Marco Polo

Feb 25

VCE8:35 pmVenice Marco Polo

34h 05m

2 stops

DSM11:40 pmDes Moines

$444

Find similar

British Airways

Mar 10

DSM1:38 pmDes Moines

25h 57m

2 stops

LIN9:35 pmMilan Linate

Mar 23

LIN4:35 pmMilan Linate

37h 05m

2 stops

DSM11:40 pmDes Moines

$445

Find similar

Air Europa flights from Des Moines to Italy

Our best Air Europa deals on Des Moines to Italy flight tickets

Air Europa

Apr 13

DSM5:15 pmDes Moines

32h 40m

1 stop

VCE8:55 amVenice Marco Polo

Apr 25

VCE5:35 pmVenice Marco Polo

30h 27m

2 stops

DSM5:02 pmDes Moines

$934

Find similar

Air Europa

Jan 8

DSM6:24 amDes Moines

20h 21m

2 stops

FCO9:45 amRome Fiumicino

Jan 10

FCO6:00 amRome Fiumicino

21h 54m

2 stops

DSM8:54 pmDes Moines

$1,309

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 3/10

7:44 pm-7:45 pm

2 stops18h 01m

Milan Malpensa

Mon 3/23

8:50 pm-11:40 pm

2 stops32h 50m

$442

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Wed 2/18

1:38 pm-4:55 pm

2 stops20h 17m

Venice Marco Polo

Wed 2/25

8:35 pm-11:40 pm

2 stops34h 05m

$444

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 3/10

1:38 pm-9:35 pm

2 stops25h 57m

Milan Linate

Mon 3/23

4:35 pm-11:40 pm

2 stops37h 05m

$445

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 2/18

11:17 am-12:25 pm

2 stops18h 08m

Rome Fiumicino

Wed 2/25

1:10 pm-11:40 pm

2 stops17h 30m

$446

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 2/18

12:04 pm-10:30 am

1 stop15h 26m

Rome Fiumicino

Wed 2/25

12:40 pm-4:27 pm

1 stop34h 47m

$450

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 2/18

11:17 am-12:25 pm

2 stops18h 08m

Rome Fiumicino

Wed 2/25

8:20 pm-10:34 am

2 stops21h 14m

$454

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 2/19

5:15 pm-9:05 am

1 stop32h 50m

Milan Malpensa

Thu 2/26

11:05 am-4:27 pm

1 stop36h 22m

$457

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 2/3

12:06 pm-9:45 am

2 stops14h 39m

Rome Fiumicino

Tue 2/10

12:40 pm-9:41 am

2 stops28h 01m

$462

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 2/18

6:55 pm-9:55 am

2 stops32h 00m

Milan Malpensa

Wed 2/25

1:05 pm-2:27 pm

2 stops32h 22m

$475

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Thu 2/19

2:59 pm-2:15 pm

2 stops16h 16m

Milan Linate

Thu 2/26

6:00 am-9:41 pm

2 stops22h 41m

$519

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $635, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during December instead. Flights to Italy in December, while not as cheap as those in November, still average around $689.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 13% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	11h 21m
Direct flights	None

The fastest flight from Des Moines to Italy takes 11h 21m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 3 as of January 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $623	Free Cancellation	Rating 7.2 11,083 reviews	Search American Airlines flights
Delta	PriceFrom $641	Free Cancellation	Rating 7.9 8,017 reviews	Search Delta flights
United Airlines	PriceFrom $655	Free Cancellation	Rating 7.4 9,132 reviews	Search United Airlines flights
KLM	PriceFrom $680	Free Cancellation	Rating 7.7 1,434 reviews	Search KLM flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.