What is the cheapest airline that flies from Des Moines to Italy?

Air Canada, United Airlines, and Lufthansa are the most popular carriers operating from Des Moines to Italy

What airlines fly to Italy?

United Airlines, Delta and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. United Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 3 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 3 as of February 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$245 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:33 am - 8:05 am

DSM

MXP

14h 32m

1 stop

6:55 am - 4:54 pm

MXP

DSM

15h 59m

2 stops

$473Air France

Wed, Mar 18 - Wed, Mar 25

11:33 am - 8:05 am

DSM

MXP

14h 32m

1 stop

6:55 am - 4:54 pm

MXP

DSM

15h 59m

2 stops

$474Air France

Wed, Mar 18 - Wed, Mar 25

11:33 am - 8:05 am

DSM

MXP

14h 32m

1 stop

6:55 am - 4:54 pm

MXP

DSM

15h 59m

2 stops

$476Air France

Wed, Mar 18 - Wed, Mar 25

3:24 pm - 4:40 pm

DSM

MXP

18h 16m

2 stops

1:05 pm - 9:41 pm

MXP

DSM

39h 36m

2 stops

$489United Airlines

Sun, Feb 15 - Tue, Mar 3

12:00 pm - 10:20 pm

DSM

FLR

27h 20m

2 stops

7:05 am - 11:49 pm

FLR

DSM

23h 44m

2 stops

$492British Airways

Wed, Apr 15 - Wed, Apr 22

6:55 pm - 7:45 am

DSM

FCO

29h 50m

1 stop

10:15 am - 8:27 pm

FCO

DSM

40h 12m

2 stops

$494United Airlines

Mon, Mar 2 - Mon, Mar 9

10:57 am - 2:25 pm

DSM

FLR

20h 28m

2 stops

6:40 am - 8:45 pm

FLR

DSM

20h 05m

2 stops

$502Delta

Tue, Mar 3 - Thu, Mar 12

11:33 am - 10:20 am

DSM

VCE

16h 47m

2 stops

6:10 am - 8:45 pm

VCE

DSM

20h 35m

2 stops

$511Delta

Wed, Mar 18 - Wed, Mar 25

7:44 pm - 7:35 pm

DSM

FCO

17h 51m

2 stops

7:50 am - 6:19 pm

FCO

DSM

16h 29m

2 stops

$523British Airways

Mon, Mar 9 - Mon, Mar 16

1:38 pm - 1:55 pm

DSM

FCO

17h 17m

2 stops

12:20 pm - 11:40 pm

FCO

DSM

17h 20m

2 stops

$530American Airlines

Mon, Mar 2 - Mon, Mar 16

Delta flights from Des Moines to Italy

Our best Delta deals on Des Moines to Italy flight tickets

Delta

Mar 3

DSM10:57 amDes Moines

20h 28m

2 stops

FLR2:25 pmFlorence Peretola

Mar 12

FLR6:40 amFlorence Peretola

20h 05m

2 stops

DSM8:45 pmDes Moines

$502

Delta

Feb 15

DSM10:40 amDes Moines

16h 55m

2 stops

MXP10:35 amMilan Malpensa

Feb 26

MXP11:05 amMilan Malpensa

18h 23m

1 stop

DSM10:28 pmDes Moines

$506

Delta

Feb 16

DSM5:15 pmDes Moines

32h 50m

1 stop

MXP9:05 amMilan Malpensa

Mar 3

MXP11:05 amMilan Malpensa

18h 23m

1 stop

DSM10:28 pmDes Moines

$507

United Airlines flights from Des Moines to Italy

Our best United Airlines deals on Des Moines to Italy flight tickets

United Airlines

Feb 15

DSM3:24 pmDes Moines

18h 16m

2 stops

MXP4:40 pmMilan Malpensa

Mar 3

MXP1:05 pmMilan Malpensa

39h 36m

2 stops

DSM9:41 pmDes Moines

$489

United Airlines

Mar 2

DSM6:55 pmDes Moines

29h 50m

1 stop

FCO7:45 amRome Fiumicino

Mar 10

FCO12:10 pmRome Fiumicino

31h 13m

2 stops

DSM1:23 pmDes Moines

$494

United Airlines

Mar 2

DSM6:55 pmDes Moines

29h 50m

1 stop

FCO7:45 amRome Fiumicino

Mar 16

FCO9:45 amRome Fiumicino

17h 55m

1 stop

DSM9:40 pmDes Moines

$495

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 3/18

11:33 am-8:05 am

1 stop14h 32m

Milan Malpensa

Wed 3/25

6:55 am-4:54 pm

2 stops15h 59m

$473

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 3/18

11:33 am-8:05 am

1 stop14h 32m

Milan Malpensa

Wed 3/25

6:55 am-4:54 pm

2 stops15h 59m

$474

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 3/18

11:33 am-8:05 am

1 stop14h 32m

Milan Malpensa

Wed 3/25

6:55 am-4:54 pm

2 stops15h 59m

$476

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 2/15

3:24 pm-4:40 pm

2 stops18h 16m

Milan Malpensa

Tue 3/3

1:05 pm-9:41 pm

2 stops39h 36m

$489

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

12:00 pm-10:20 pm

2 stops27h 20m

Florence Peretola

Wed 4/22

7:05 am-11:49 pm

2 stops23h 44m

$492

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 3/2

6:55 pm-7:45 am

1 stop29h 50m

Rome Fiumicino

Mon 3/9

10:15 am-8:27 pm

2 stops40h 12m

$494

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 3/3

10:57 am-2:25 pm

2 stops20h 28m

Florence Peretola

Thu 3/12

6:40 am-8:45 pm

2 stops20h 05m

$502

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Wed 3/18

11:33 am-10:20 am

2 stops16h 47m

Venice Marco Polo

Wed 3/25

6:10 am-8:45 pm

2 stops20h 35m

$511

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 3/9

7:44 pm-7:35 pm

2 stops17h 51m

Rome Fiumicino

Mon 3/16

7:50 am-6:19 pm

2 stops16h 29m

$523

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 3/2

1:38 pm-1:55 pm

2 stops17h 17m

Rome Fiumicino

Mon 3/16

12:20 pm-11:40 pm

2 stops17h 20m

$530

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $635, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during December instead. Flights to Italy in December, while not as cheap as those in November, still average around $689.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 9% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 00m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 00m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 3 as of February 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
KLM	PriceFrom $457	Free Cancellation	Rating 7.7 1,448 reviews	Search KLM flights
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,236 reviews	Search United Airlines flights
Delta	PriceFrom $505	Free Cancellation	Rating 7.9 8,138 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.