What is the cheapest airline that flies from Des Moines to Italy?

Air Canada, Lufthansa, and United Airlines are the most popular carriers operating from Des Moines to Italy

What airlines fly to Italy?

United Airlines, Delta and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. United Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 3 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 4 as of November 2025.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$272 Cheap Flights from Des Moines to Italy in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 10:55 amDSM-FCO

43h 55m2 stops

12:45 pm - 11:44 pmFCO-DSM

41h 59m2 stops

$484Air Canada

Find Deal

Sun, Feb 1 - Sun, Feb 8

6:48 pm - 9:25 amDSM-FCO

55h 37m2 stops

11:15 am - 9:51 pmFCO-DSM

41h 36m2 stops

$488Air Canada

Find Deal

Fri, Feb 6 - Mon, Feb 16

1:35 pm - 9:25 amDSM-FCO

36h 50m2 stops

12:50 pm - 11:44 pmFCO-DSM

41h 54m2 stops

$490United Airlines

Find Deal

Thu, Jan 8 - Thu, Jan 22

3:38 pm - 3:20 pmDSM-FCO

16h 42m2 stops

1:10 pm - 5:09 pmFCO-DSM

34h 59m1 stop

$492American Airlines

Find Deal

Thu, Dec 11 - Thu, Dec 18

11:26 am - 1:05 pmDSM-MXP

18h 39m1 stop

1:05 pm - 9:37 pmMXP-DSM

39h 32m2 stops

$542United Airlines

Find Deal

Sun, Nov 23 - Sun, Dec 14

7:46 am - 9:45 amDSM-MXP

18h 59m1 stop

11:05 am - 10:34 pmMXP-DSM

18h 29m1 stop

$550Delta

Find Deal

Sun, Nov 23 - Tue, Dec 16

3:17 pm - 6:50 pmDSM-MXP

20h 33m2 stops

11:05 am - 10:34 pmMXP-DSM

18h 29m1 stop

$553Delta

Find Deal

Sun, Nov 23 - Tue, Dec 16

2:17 pm - 10:30 amDSM-FCO

13h 13m1 stop

6:10 am - 4:58 pmFCO-DSM

17h 48m2 stops

$656KLM

Find Deal

Mon, Nov 24 - Sat, Dec 13

6:33 pm - 7:50 pmDSM-FLR

18h 17m2 stops

8:45 pm - 8:02 pmFLR-DSM

30h 17m2 stops

$674KLM

Find Deal

Tue, Dec 16 - Tue, Dec 23

8:51 am - 8:05 amDSM-MXP

16h 14m2 stops

10:25 am - 11:38 pmMXP-DSM

20h 13m2 stops

$806American Airlines

Find Deal

Thu, Nov 20 - Tue, Nov 25

Lufthansa flights from Des Moines to Italy

Our best Lufthansa deals on Des Moines to Italy flight tickets

Lufthansa

Mar 23

DSM11:30 amDes Moines

23h 00m

2 stops

FLR4:30 pmFlorence Peretola

Mar 30

FLR5:20 pmFlorence Peretola

35h 16m

2 stops

DSM9:36 pmDes Moines

$600

Find similar

Lufthansa

Mar 17

DSM6:45 pmDes Moines

17h 30m

2 stops

FCO6:15 pmRome Fiumicino

Mar 30

FCO3:55 pmRome Fiumicino

36h 41m

2 stops

DSM9:36 pmDes Moines

$612

Find similar

Lufthansa

Nov 24

DSM6:50 pmDes Moines

21h 10m

2 stops

FCO11:00 pmRome Fiumicino

Dec 15

FCO7:05 pmRome Fiumicino

33h 45m

2 stops

DSM9:50 pmDes Moines

$619

Find similar

Air Canada flights from Des Moines to Italy

Our best Air Canada deals on Des Moines to Italy flight tickets

Air Canada

Feb 1

DSM8:00 amDes Moines

43h 55m

2 stops

FCO10:55 amRome Fiumicino

Feb 8

FCO12:45 pmRome Fiumicino

41h 59m

2 stops

DSM11:44 pmDes Moines

$484

Find similar

Air Canada

Feb 6

DSM6:48 pmDes Moines

55h 37m

2 stops

FCO9:25 amRome Fiumicino

Feb 16

FCO11:15 amRome Fiumicino

41h 36m

2 stops

DSM9:51 pmDes Moines

$488

Find similar

Air Canada

Nov 26

DSM3:15 pmDes Moines

35h 40m

2 stops

MXP9:55 amMilan Malpensa

Dec 14

MXP1:05 pmMilan Malpensa

41h 39m

3 stops

DSM11:44 pmDes Moines

$527

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 2/1

8:00 am-10:55 am

2 stops43h 55m

Rome Fiumicino

Sun 2/8

12:45 pm-11:44 pm

2 stops41h 59m

$484

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Fri 2/6

6:48 pm-9:25 am

2 stops55h 37m

Rome Fiumicino

Mon 2/16

11:15 am-9:51 pm

2 stops41h 36m

$488

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Thu 1/8

1:35 pm-9:25 am

2 stops36h 50m

Rome Fiumicino

Thu 1/22

12:50 pm-11:44 pm

2 stops41h 54m

$490

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Thu 12/11

3:38 pm-3:20 pm

2 stops16h 42m

Rome Fiumicino

Thu 12/18

1:10 pm-5:09 pm

1 stop34h 59m

$492

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/23

11:26 am-1:05 pm

1 stop18h 39m

Milan Malpensa

Sun 12/14

1:05 pm-9:37 pm

2 stops39h 32m

$542

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/23

7:46 am-9:45 am

1 stop18h 59m

Milan Malpensa

Tue 12/16

11:05 am-10:34 pm

1 stop18h 29m

$550

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/23

3:17 pm-6:50 pm

2 stops20h 33m

Milan Malpensa

Tue 12/16

11:05 am-10:34 pm

1 stop18h 29m

$553

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 11/24

2:17 pm-10:30 am

1 stop13h 13m

Rome Fiumicino

Sat 12/13

6:10 am-4:58 pm

2 stops17h 48m

$656

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 12/16

6:33 pm-7:50 pm

2 stops18h 17m

Florence Peretola

Tue 12/23

8:45 pm-8:02 pm

2 stops30h 17m

$674

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 11/20

8:51 am-8:05 am

2 stops16h 14m

Milan Malpensa

Tue 11/25

10:25 am-11:38 pm

2 stops20h 13m

$806

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in November. Flight prices, which tend to average around $654, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Italy from Des Moines during December instead. Flights to Italy in December, while not as cheap as those in November, still average around $773.

What is the cheapest day to depart on your flight to Italy?

According to our data, Tuesday is the cheapest day to fly to Italy from Des Moines. The lowest ticket price found for a Tuesday departure recently was $1,012. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Italy for around $1,591.

What is the cheapest time of day to depart on your flight to Italy?

Our data shows that the cheapest Des Moines to Italy flights are usually those with departure times in the afternoon. Our users have found flights to Italy in the afternoon for as low as $1,222. In contrast, the most expensive time of day to depart to Italy is at noon when prices are around $1,332.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 20% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Direct flights	None

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 4 as of November 2025.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $641	Free Cancellation	Rating 7.9 8,001 reviews	Search Delta flights
United Airlines	PriceFrom $655	Free Cancellation	Rating 7.4 8,997 reviews	Search United Airlines flights
KLM	PriceFrom $680	Free Cancellation	Rating 7.7 1,404 reviews	Search KLM flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Italy trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Wed 12/3

Wed 12/10

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Italy

Popular cities in Italy

Flights to Romefrom $321

Flights to Milanfrom $324

Flights to Venicefrom $346

Flights to Naplesfrom $344

Flights to Florencefrom $335

Flights to Cataniafrom $399

Flights to Palermofrom $406

Flights to Bolognafrom $346

Flights to Barifrom $390

Flights to Olbiafrom $510

Flights to Pisafrom $428

Flights to Cagliarifrom $508

Cheap flights from Des Moines to Italy from $272

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Italy departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Des Moines to Italy

Cheap round-trip flights

Cheap one-way flights

Lufthansa flights from Des Moines to Italy

Our best Lufthansa deals on Des Moines to Italy flight tickets

Air Canada flights from Des Moines to Italy

Our best Air Canada deals on Des Moines to Italy flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

See travel insights to Italy from

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Italy?

What is the cheapest day to depart on your flight to Italy?

What is the cheapest time of day to depart on your flight to Italy?

Our data shows that the cheapest Des Moines to Italy flights are usually those with departure times in the afternoon. Our users have found flights to Italy in the afternoon for as low as $1,222. In contrast, the most expensive time of day to depart to Italy is at noon when prices are around $1,332.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 20% on your flight if you consider stops on a Des Moines to Italy flight.

What is the cheapest airline that flies from Des Moines to Italy?

Air Canada, Lufthansa, and United Airlines are the most popular carriers operating from Des Moines to Italy

What airlines fly to Italy?

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Direct flights

When did momondo last update prices for flights from Des Moines Airport to Italy?

How many operators does momondo search for flights from Des Moines Airport to Italy?

How old do you have to be to fly from Des Moines Airport to Italy?

What documentation or ID do you need to fly to Italy?

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

How can momondo help me find flights from Des Moines to Italy?

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

An easier way to manage your Italy trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Italy

Popular cities in Italy

Popular flights according to clicks in the last 7 days on momondo