What airlines fly to Italy?

Delta, United Airlines and KLM are the top three most popular airlines that fly to Italy from Des Moines according to our data. Delta is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Italy. Keep in mind that there are 3 different airlines that fly to Italy on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Italy?

KLM, Aer Lingus, and British Airways are the most popular carriers operating from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?

Prices for flights from Des Moines Airport to Italy were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Italy?

The number of operators available for flights from Des Moines Airport to Italy is 3 as of May 2026.

How old do you have to be to fly from Des Moines Airport to Italy?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.

What documentation or ID do you need to fly to Italy?

The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$355 Cheap Flights from Des Moines to Italy in 2026

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Find the cheapest flights from Des Moines to Italy

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 7:30 am

DSM

MXP

18h 15m

2 stops

3:05 pm - 12:40 am

MXP

DSM

16h 35m

1 stop

$743United Airlines

Sun, Nov 15 - Thu, Nov 19

8:00 am - 10:20 am

DSM

MXP

19h 20m

2 stops

12:20 pm - 10:31 am

MXP

DSM

29h 11m

2 stops

$750Multiple Airlines

Tue, Oct 13 - Wed, Oct 21

8:00 am - 10:20 am

DSM

MXP

19h 20m

2 stops

12:20 pm - 10:31 am

MXP

DSM

29h 11m

2 stops

$751Air Canada

Tue, Oct 13 - Wed, Oct 21

1:43 pm - 1:25 pm

DSM

MXP

16h 42m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$763American Airlines

Tue, Oct 13 - Wed, Oct 21

1:43 pm - 1:25 pm

DSM

MXP

16h 42m

2 stops

2:20 pm - 11:55 pm

MXP

DSM

16h 35m

1 stop

$764American Airlines

Tue, Oct 13 - Wed, Oct 21

2:15 pm - 9:25 am

DSM

MXP

12h 10m

1 stop

11:40 am - 10:29 pm

MXP

DSM

17h 49m

1 stop

$767KLM

Tue, Oct 13 - Wed, Oct 21

6:30 pm - 9:25 am

DSM

MXP

31h 55m

1 stop

11:40 am - 10:29 pm

MXP

DSM

17h 49m

1 stop

$772Delta

Tue, Oct 13 - Fri, Oct 23

5:25 pm - 3:55 pm

DSM

LIN

15h 30m

2 stops

6:40 am - 7:12 pm

LIN

DSM

19h 32m

2 stops

$783Delta

Tue, Oct 13 - Fri, Oct 23

5:40 am - 10:50 am

DSM

FCO

22h 10m

1 stop

1:10 pm - 10:37 pm

FCO

DSM

16h 27m

1 stop

$791KLM

Tue, Aug 18 - Tue, Aug 25

11:32 am - 9:15 am

DSM

FCO

14h 43m

2 stops

11:30 am - 2:16 pm

FCO

DSM

33h 46m

2 stops

$808Air Canada

Tue, Aug 11 - Thu, Aug 20

Iberia flights from Des Moines to Italy

Our best Iberia deals on Des Moines to Italy flight tickets

Iberia

May 25

DSM1:48 pmDes Moines

21h 27m

2 stops

FCO6:15 pmRome Fiumicino

Jun 1

FCO8:25 pmRome Fiumicino

30h 09m

2 stops

DSM7:34 pmDes Moines

$1,401

Iberia

Jun 4

DSM1:51 pmDes Moines

22h 14m

2 stops

VCE7:05 pmVenice Marco Polo

Jun 22

VCE7:55 pmVenice Marco Polo

29h 44m

2 stops

DSM6:39 pmDes Moines

$1,499

Iberia

May 31

DSM7:01 pmDes Moines

32h 54m

1 stop

VCE10:55 amVenice Marco Polo

Jun 14

VCE1:40 pmVenice Marco Polo

25h 52m

2 stops

DSM8:32 amDes Moines

$1,681

American Airlines flights from Des Moines to Italy

Our best American Airlines deals on Des Moines to Italy flight tickets

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 42m

2 stops

MXP1:25 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$763

American Airlines

Oct 13

DSM1:43 pmDes Moines

16h 42m

2 stops

MXP1:25 pmMilan Malpensa

Oct 21

MXP2:20 pmMilan Malpensa

16h 35m

1 stop

DSM11:55 pmDes Moines

$764

American Airlines

Oct 6

DSM2:37 pmDes Moines

15h 53m

2 stops

LIN1:30 pmMilan Linate

Oct 14

LIN11:40 amMilan Linate

19h 15m

2 stops

DSM11:55 pmDes Moines

$798

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 11/15

6:15 am-7:30 am

2 stops18h 15m

Milan Malpensa

Thu 11/19

3:05 pm-12:40 am

1 stop16h 35m

$743

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

8:00 am-10:20 am

2 stops19h 20m

Milan Malpensa

Wed 10/21

12:20 pm-10:31 am

2 stops29h 11m

$750

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

8:00 am-10:20 am

2 stops19h 20m

Milan Malpensa

Wed 10/21

12:20 pm-10:31 am

2 stops29h 11m

$751

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

1:43 pm-1:25 pm

2 stops16h 42m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$763

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

1:43 pm-1:25 pm

2 stops16h 42m

Milan Malpensa

Wed 10/21

2:20 pm-11:55 pm

1 stop16h 35m

$764

Quickest round-trip

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

2:15 pm-9:25 am

1 stop12h 10m

Milan Malpensa

Wed 10/21

11:40 am-10:29 pm

1 stop17h 49m

$767

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 10/13

6:30 pm-9:25 am

1 stop31h 55m

Milan Malpensa

Fri 10/23

11:40 am-10:29 pm

1 stop17h 49m

$772

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Tue 10/13

5:25 pm-3:55 pm

2 stops15h 30m

Milan Linate

Fri 10/23

6:40 am-7:12 pm

2 stops19h 32m

$783

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/18

5:40 am-10:50 am

1 stop22h 10m

Rome Fiumicino

Tue 8/25

1:10 pm-10:37 pm

1 stop16h 27m

$791

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

11:32 am-9:15 am

2 stops14h 43m

Rome Fiumicino

Thu 8/20

11:30 am-2:16 pm

2 stops33h 46m

$808

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Italy from Des Moines during August instead. Flights to Italy in August, while not as cheap as those in January, still average around $492.

Can stopping save me money on Des Moines to Italy flights?

You could potentially save up to 41% on your flight if you consider stops on a Des Moines to Italy flight.

Cheap Des Moines to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Italy

Fastest flight time	12h 52m
Direct flights	None

The fastest flight from Des Moines to Italy takes 12h 52m

There are no direct flights from Des Moines to Italy. There are no popular flight routes from Des Moines to Italy.

Search flight deals

Frequently asked questions about flying from Des Moines to Italy

When did momondo last update prices for flights from Des Moines Airport to Italy?
Prices for flights from Des Moines Airport to Italy were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Italy?
The number of operators available for flights from Des Moines Airport to Italy is 3 as of May 2026.
How old do you have to be to fly from Des Moines Airport to Italy?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Italy.
What documentation or ID do you need to fly to Italy?
The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Italy

Compare and see reviews for airlines that fly from Des Moines to Italy with momondo

Airline	Rating	Free Cancellation	Price
KLM	PriceFrom $457	Free Cancellation	Rating 7.8 1,519 reviews	Search KLM flights
United Airlines	PriceFrom $491	Free Cancellation	Rating 7.4 9,751 reviews	Search United Airlines flights
Delta	PriceFrom $655	Free Cancellation	Rating 7.9 8,449 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Italy?

Finding the right flight to Italy from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Italy quick and easy, saving you time and money.

Can I find flights from Des Moines to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Italy?

Once all potential Des Moines to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.