What airlines fly to South America?

Copa Airlines, Avianca and American Airlines are the top three most popular airlines that fly to South America from Chicago according to our data. Copa Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 11 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to South America on average per day?

The number of flights available between Chicago and South America is 4 per day as of May 2026. The most frequent departure time is 11:00PM, with 100% of daily flights leaving in the evening.

How many flights depart from Chicago to South America on average per week?

The number of flights available between Chicago and South America is 28 per week as of May 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.

What is the cheapest airline that flies from Chicago to South America?

Copa Airlines, American Airlines, and Delta are the most popular carriers operating from Chicago to South America

When did momondo last update prices for flights from Chicago to South America?

Prices for flights from Chicago to South America refresh daily.

How many operators does momondo search for flights from Chicago to South America?

There are 11 operators available for flights from Chicago to South America as of May 2026.

How old do you have to be to fly from Chicago to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$133 Cheap Flights from Chicago to South America in 2026

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Find the cheapest flights from Chicago to South America

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:01 am - 5:55 pm

ORD

CTG

9h 54m

1 stop

6:20 am - 1:02 am

CTG

ORD

18h 42m

1 stop

$343Copa Airlines

Thu, Sep 10 - Tue, Sep 15

8:01 am - 11:00 pm

ORD

CTG

14h 59m

1 stop

6:20 am - 1:02 am

CTG

ORD

18h 42m

1 stop

$358Copa Airlines

Thu, Sep 10 - Tue, Sep 15

8:34 pm - 12:05 pm

ORD

CTG

15h 31m

2 stops

2:34 pm - 11:08 pm

CTG

ORD

9h 34m

1 stop

$360American Airlines

Mon, Oct 19 - Fri, Nov 6

6:00 pm - 2:13 pm

ORD

CTG

20h 13m

1 stop

1:35 pm - 12:24 am

CTG

ORD

10h 49m

1 stop

$364American Airlines

Fri, May 29 - Wed, Jun 3

8:15 am - 7:15 pm

ORD

BOG

11h 00m

1 stop

2:55 pm - 11:57 pm

BOG

ORD

9h 02m

1 stop

$364LATAM Airlines

Mon, Sep 14 - Mon, Sep 21

5:55 pm - 1:40 pm

ORD

BOG

19h 45m

1 stop

2:55 pm - 11:57 pm

BOG

ORD

9h 02m

1 stop

$373LATAM Airlines

Sat, Sep 5 - Mon, Sep 14

11:20 pm - 1:35 pm

ORD

CTG

14h 15m

1 stop

7:45 am - 9:20 pm

CTG

ORD

13h 35m

1 stop

$378Avianca

Thu, Sep 10 - Tue, Sep 15

11:20 pm - 2:35 pm

ORD

CTG

15h 15m

1 stop

8:25 am - 8:20 pm

CTG

ORD

12h 55m

1 stop

$379Avianca

Thu, Oct 29 - Mon, Nov 2

7:30 am - 9:10 pm

ORD

MDE

13h 40m

1 stop

10:45 am - 12:15 am

MDE

ORD

14h 30m

1 stop

$417United Airlines

Sat, Aug 29 - Fri, Dec 18

9:35 pm - 9:10 pm

ORD

MDE

23h 35m

1 stop

10:45 am - 12:15 am

MDE

ORD

14h 30m

1 stop

$426United Airlines

Thu, Aug 27 - Fri, Dec 18

LATAM Airlines flights from Chicago to South America

Our best LATAM Airlines deals on Chicago to South America flight tickets

LATAM Airlines

Sep 5

ORD5:55 pmChicago O'Hare Intl

19h 45m

1 stop

BOG1:40 pmBogotá El Dorado

Sep 14

BOG2:55 pmBogotá El Dorado

9h 02m

1 stop

ORD11:57 pmChicago O'Hare Intl

$373

LATAM Airlines

May 31

ORD9:49 amChicago O'Hare Intl

9h 26m

1 stop

BOG7:15 pmBogotá El Dorado

Jun 4

BOG2:55 pmBogotá El Dorado

19h 21m

1 stop

ORD10:16 amChicago O'Hare Intl

$374

LATAM Airlines

Jun 4

ORD11:26 amChicago O'Hare Intl

7h 49m

1 stop

BOG7:15 pmBogotá El Dorado

Jun 9

BOG2:55 pmBogotá El Dorado

9h 04m

1 stop

ORD11:59 pmChicago O'Hare Intl

$378

American Airlines flights from Chicago to South America

Our best American Airlines deals on Chicago to South America flight tickets

American Airlines

Oct 19

ORD8:34 pmChicago O'Hare Intl

15h 31m

2 stops

CTG12:05 pmCartagena Rafael Nunez

Nov 6

CTG2:34 pmCartagena Rafael Nunez

9h 34m

1 stop

ORD11:08 pmChicago O'Hare Intl

$360

American Airlines

May 29

ORD6:00 pmChicago O'Hare Intl

20h 13m

1 stop

CTG2:13 pmCartagena Rafael Nunez

Jun 3

CTG1:35 pmCartagena Rafael Nunez

10h 49m

1 stop

ORD12:24 amChicago O'Hare Intl

$364

American Airlines

May 29

ORD6:00 pmChicago O'Hare Intl

20h 13m

1 stop

CTG2:13 pmCartagena Rafael Nunez

Jun 3

CTG3:15 pmCartagena Rafael Nunez

15h 42m

2 stops

ORD6:57 amChicago O'Hare Intl

$369

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 9/10

8:01 am-5:55 pm

1 stop9h 54m

Cartagena Rafael Nunez

Tue 9/15

6:20 am-1:02 am

1 stop18h 42m

$343

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 9/10

8:01 am-11:00 pm

1 stop14h 59m

Cartagena Rafael Nunez

Tue 9/15

6:20 am-1:02 am

1 stop18h 42m

$358

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Mon 10/19

8:34 pm-12:05 pm

2 stops15h 31m

Cartagena Rafael Nunez

Fri 11/6

2:34 pm-11:08 pm

1 stop9h 34m

$360

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Fri 5/29

6:00 pm-2:13 pm

1 stop20h 13m

Cartagena Rafael Nunez

Wed 6/3

1:35 pm-12:24 am

1 stop10h 49m

$364

Quickest round-trip

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Mon 9/14

8:15 am-7:15 pm

1 stop11h 00m

Bogotá El Dorado

Mon 9/21

2:55 pm-11:57 pm

1 stop9h 02m

$364

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sat 9/5

5:55 pm-1:40 pm

1 stop19h 45m

Bogotá El Dorado

Mon 9/14

2:55 pm-11:57 pm

1 stop9h 02m

$373

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 9/10

11:20 pm-1:35 pm

1 stop14h 15m

Cartagena Rafael Nunez

Tue 9/15

7:45 am-9:20 pm

1 stop13h 35m

$378

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 10/29

11:20 pm-2:35 pm

1 stop15h 15m

Cartagena Rafael Nunez

Mon 11/2

8:25 am-8:20 pm

1 stop12h 55m

$379

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sat 8/29

7:30 am-9:10 pm

1 stop13h 40m

Medellín Jose Maria Cordova Intl

Fri 12/18

10:45 am-12:15 am

1 stop14h 30m

$417

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Thu 8/27

9:35 pm-9:10 pm

1 stop23h 35m

Medellín Jose Maria Cordova Intl

Fri 12/18

10:45 am-12:15 am

1 stop14h 30m

$426

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Chicago to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $452. If you aren’t able to travel during the month of April, then book flights to South America from Chicago during September instead. Flights to South America in September, while not as cheap as those in April, still average around $488.

What is the cheapest Chicago to South America flight route?

Fly from Chicago O'Hare Intl to Bogotá El Dorado for the best Chicago - South America flight prices

How far in advance should I book a flight from Chicago to South America?

You are more likely to see cheaper flights to South America from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $631 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Chicago for as low as $576 on momondo.

Can stopping save me money on Chicago to South America flights?

You could potentially save up to 23% on your flight if you consider stops on a Chicago to South America flight.

Cheap Chicago to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South America

Best Price Found	$232
Fastest flight time	6h 10m
Direct flights	Every day
Airports in South America	464 airports

The best one-way flight to South America from Chicago in the past 72 hours is $232. The best round-trip flight deal from Chicago to South America found on momondo in the last 72 hours is $437.

The fastest flight from Chicago to South America takes 6h 10m

Direct flights go from Chicago to South America every day.

There are 464 airports in South America. From Chicago there are direct flights to Bogotá El Dorado (BOG).

Search flight deals

Frequently asked questions about flying from Chicago to South America

When did momondo last update prices for flights from Chicago to South America?
Prices for flights from Chicago to South America refresh daily.
How many operators does momondo search for flights from Chicago to South America?
There are 11 operators available for flights from Chicago to South America as of May 2026.
How old do you have to be to fly from Chicago to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago to South America?
Based on momondo bookings for flights between Chicago and South America, the leading plane model is Airbus A320neo, making up 39.50% of the total bookings. Other popular models include Boeing 787-10 Dreamliner with 32.88%, Boeing 737-800 with 8.45%, and Boeing 737 MAX 8 with 6.62%.

Best airlines flying from Chicago to South America

Compare and see reviews for airlines that fly from Chicago to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $126	Free Cancellation	Rating 6.2 8,626 reviews	Search Spirit Airlines flights
Delta	PriceFrom $153	Free Cancellation	Rating 7.9 8,453 reviews	Search Delta flights
LATAM Airlines	PriceFrom $212	Free Cancellation	Rating 7.4 1,922 reviews	Search LATAM Airlines flights
Arajet	PriceFrom $264	Free Cancellation	Rating 6.5 48 reviews	Search Arajet flights
Copa Airlines	PriceFrom $272	Free Cancellation	Rating 7.5 1,585 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $295	Free Cancellation	Rating 7.1 11,662 reviews	Search American Airlines flights
Avianca	PriceFrom $297	Free Cancellation	Rating 6.5 2,527 reviews	Search Avianca flights
United Airlines	PriceFrom $302	Free Cancellation	Rating 7.4 9,717 reviews	Search United Airlines flights
GOL	PriceFrom $450	Free Cancellation	Rating 7.3 1,219 reviews	Search GOL flights
Air Canada	PriceFrom $479	Free Cancellation	Rating 7.1 11,042 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South America?

Once all potential Chicago to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to South America

Popular cities

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Airlines

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Complete your trip

Feeling lucky

Popular cities in South America

Flights to Limafrom $351

Flights to Sao Paulofrom $364

Flights to Buenos Airesfrom $437

Flights to Bogotáfrom $301

Flights to Rio de Janeirofrom $441

Flights to Medellínfrom $277

Flights to Santiagofrom $425

Flights to Cartagenafrom $277

Flights to Quitofrom $371

Flights to Guayaquilfrom $295

Flights to Califrom $346

Flights to Cuscofrom $450

Cheap flights from Chicago to South America from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South America departing on 8/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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LATAM Airlines flights from Chicago to South America

Our best LATAM Airlines deals on Chicago to South America flight tickets

American Airlines flights from Chicago to South America

Our best American Airlines deals on Chicago to South America flight tickets

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Use the filters below to find and compare flights from Chicago to South America that are best for you.

How to get the cheapest flight ticket from Chicago to South America

What is the cheapest month to fly to South America?

What is the cheapest Chicago to South America flight route?

How far in advance should I book a flight from Chicago to South America?

Can stopping save me money on Chicago to South America flights?

What is the cheapest airline that flies from Chicago to South America?

What airlines fly to South America?

How many flights depart from Chicago to South America on average per day?

How many flights depart from Chicago to South America on average per week?

Cheap Chicago to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South America

Best Price Found

Fastest flight time

Direct flights

Airports in South America

Frequently asked questions about flying from Chicago to South America

Best airlines flying from Chicago to South America

Compare and see reviews for airlines that fly from Chicago to South America with momondo

Why use momondo?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo

Chicago flight routes

According to popular flight searches on momondo this year

South America flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to South America

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to South America

List of cabin classes available on flights landing in South America. Availability may vary depending on flight origin and airline.

Complete your trip to South America

Explore popular destinations other users love

According to popular flight searches on momondo this year