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Cheap flights from Chicago to South America from $73

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South America departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:15 am - 1:10 pm
ORD
-
CTG
6h 55m
1 stop
Spirit Airlines Logo
1:21 pm - 5:46 pm
CTG
-
ORD
28h 25m
2 stops
$267Spirit Airlines
Tue, Mar 3 - Tue, Mar 10
Spirit Airlines Logo
5:15 am - 1:10 pm
ORD
-
CTG
6h 55m
1 stop
Spirit Airlines Logo
2:21 pm - 11:47 pm
CTG
-
ORD
10h 26m
1 stop
$269Spirit Airlines
Sun, Feb 22 - Tue, Mar 3
Copa Airlines Logo
7:34 am - 12:05 am
ORD
-
BOG
15h 31m
1 stop
Copa Airlines Logo
6:08 pm - 12:31 pm
BOG
-
ORD
19h 23m
1 stop
$281Copa Airlines
Tue, Feb 17 - Tue, Feb 24
Avianca Logo
10:20 pm - 11:50 pm
ORD
-
UIO
24h 30m
1 stop
Avianca Logo
7:05 pm - 8:20 pm
UIO
-
ORD
26h 15m
1 stop
$365Avianca
Thu, Feb 19 - Mon, Feb 23
American Airlines Logo
8:41 am - 10:59 pm
ORD
-
UIO
13h 18m
1 stop
American Airlines Logo
11:44 pm - 1:34 pm
UIO
-
ORD
13h 50m
2 stops
$372American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
6:40 am - 7:37 pm
ORD
-
UIO
12h 57m
2 stops
American Airlines Logo
7:05 am - 9:38 pm
UIO
-
ORD
14h 33m
1 stop
$373American Airlines
Tue, Apr 14 - Thu, Apr 23
Copa Airlines Logo
3:22 pm - 12:31 am
ORD
-
UIO
9h 09m
1 stop
Copa Airlines Logo
6:33 pm - 1:04 am
UIO
-
ORD
30h 31m
1 stop
$375Copa Airlines
Mon, Mar 16 - Sun, Mar 22
Avianca Logo
11:20 pm - 1:10 pm
ORD
-
UIO
13h 50m
1 stop
Avianca Logo
10:10 am - 9:20 pm
UIO
-
ORD
11h 10m
1 stop
$379Avianca
Fri, Mar 27 - Mon, Apr 6
LATAM Airlines Logo
6:00 am - 7:20 pm
MDW
-
MDE
12h 20m
2 stops
LATAM Airlines Logo
5:35 am - 10:31 pm
MDE
-
MDW
17h 56m
2 stops
$438LATAM Airlines
Thu, Feb 26 - Mon, Mar 2
LATAM Airlines Logo
6:00 am - 6:00 pm
MDW
-
MDE
11h 00m
2 stops
LATAM Airlines Logo
5:35 am - 5:45 pm
MDE
-
MDW
13h 10m
2 stops
$508LATAM Airlines
Thu, Feb 26 - Mon, Mar 2

United Airlines flights from Chicago to South America

Our best United Airlines deals on Chicago to South America flight tickets
United Airlines
May 1
ORD6:25 pmChicago O'Hare Intl
10h 29m
1 stop
BOG4:54 amBogotá El Dorado
May 20
BOG8:30 amBogotá El Dorado
16h 57m
1 stop
ORD1:27 amChicago O'Hare Intl
$305
United Airlines
Feb 3
ORD8:54 amChicago O'Hare Intl
12h 41m
1 stop
BOG10:35 pmBogotá El Dorado
Feb 15
BOG8:15 amBogotá El Dorado
24h 31m
1 stop
ORD7:46 amChicago O'Hare Intl
$312
United Airlines
Feb 10
ORD5:40 amChicago O'Hare Intl
15h 25m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 14
MDE10:45 amMedellín Jose Maria Cordova Intl
14h 41m
1 stop
ORD12:26 amChicago O'Hare Intl
$317

LATAM Airlines flights from Chicago to South America

Our best LATAM Airlines deals on Chicago to South America flight tickets
LATAM Airlines
Feb 14
ORD5:25 amChicago O'Hare Intl
13h 05m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 21
BOG3:55 pmBogotá El Dorado
9h 01m
1 stop
ORD11:56 pmChicago O'Hare Intl
$325
LATAM Airlines
Feb 5
ORD7:05 amChicago O'Hare Intl
12h 15m
2 stops
BOG8:20 pmBogotá El Dorado
Feb 8
BOG9:00 amBogotá El Dorado
15h 55m
1 stop
ORD11:55 pmChicago O'Hare Intl
$328
LATAM Airlines
Feb 18
ORD9:52 amChicago O'Hare Intl
8h 38m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 25
BOG10:55 amBogotá El Dorado
24h 01m
2 stops
ORD9:56 amChicago O'Hare Intl
$329

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Chicago to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Tue 3/3

5:15 am-1:10 pm

1 stop6h 55m

Cartagena Rafael Nunez

Tue 3/10

1:21 pm-5:46 pm

2 stops28h 25m

$267

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sun 2/22

5:15 am-1:10 pm

1 stop6h 55m

Cartagena Rafael Nunez

Tue 3/3

2:21 pm-11:47 pm

1 stop10h 26m

$269

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Tue 2/17

7:34 am-12:05 am

1 stop15h 31m

Bogotá El Dorado

Tue 2/24

6:08 pm-12:31 pm

1 stop19h 23m

$281

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Thu 2/19

10:20 pm-11:50 pm

1 stop24h 30m

Quito Mariscal Sucr

Mon 2/23

7:05 pm-8:20 pm

1 stop26h 15m

$365

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Tue 3/3

8:41 am-10:59 pm

1 stop13h 18m

Quito Mariscal Sucr

Tue 3/10

11:44 pm-1:34 pm

2 stops13h 50m

$372

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Tue 4/14

6:40 am-7:37 pm

2 stops12h 57m

Quito Mariscal Sucr

Thu 4/23

7:05 am-9:38 pm

1 stop14h 33m

$373

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Mon 3/16

3:22 pm-12:31 am

1 stop9h 09m

Quito Mariscal Sucr

Sun 3/22

6:33 pm-1:04 am

1 stop30h 31m

$375

ChicagoQuito

ORD - UIO

ORDUIO

Chicago O'Hare Intl

Fri 3/27

11:20 pm-1:10 pm

1 stop13h 50m

Quito Mariscal Sucr

Mon 4/6

10:10 am-9:20 pm

1 stop11h 10m

$379

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Thu 2/26

6:00 am-7:20 pm

2 stops12h 20m

Medellín Jose Maria Cordova Intl

Mon 3/2

5:35 am-10:31 pm

2 stops17h 56m

$438

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Thu 2/26

6:00 am-6:00 pm

2 stops11h 00m

Medellín Jose Maria Cordova Intl

Mon 3/2

5:35 am-5:45 pm

2 stops13h 10m

$508

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Chicago to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $561. If you aren’t able to travel during the month of September, then book flights to South America from Chicago during April instead. Flights to South America in April, while not as cheap as those in September, still average around $563.

What is the cheapest Chicago to South America flight route?

Fly from Chicago O'Hare Intl to Bogotá El Dorado for the best Chicago - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $601 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Chicago for as low as $477 on momondo.

What cabin class options are available on Chicago to South America flights?

There are 3 cabin classes available to choose from on Chicago to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to South America flights?

You could potentially save up to 47% on your flight if you consider stops on a Chicago to South America flight.

Cheap Chicago to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South America

Best Price Found

$194

Fastest flight time

5h 50m

Direct flights

Every day

Airports in South America

463 airports
The best one-way flight to South America from Chicago in the past 72 hours is $194. The best round-trip flight deal from Chicago to South America found on momondo in the last 72 hours is $377.
The fastest flight from Chicago to South America takes 5h 50m
Direct flights go from Chicago to South America every day.
There are 463 airports in South America. From Chicago there are direct flights to Bogotá El Dorado (BOG).
Search flight deals

  • When did momondo last update prices for flights from Chicago to South America?

    Prices for flights from Chicago to South America refresh daily.

  • How many operators does momondo search for flights from Chicago to South America?

  • How old do you have to be to fly from Chicago to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago to South America?

Best airlines flying from Chicago to South America

Compare and see reviews for airlines that fly from Chicago to South America with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $142Free CancellationRating
7.4
9,232 reviews
Search United Airlines flights
Spirit AirlinesPriceFrom $174Free CancellationRating
6.3
8,401 reviews
Search Spirit Airlines flights
DeltaPriceFrom $244Free CancellationRating
7.9
8,138 reviews
Search Delta flights
Copa AirlinesPriceFrom $245Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $268Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
AviancaPriceFrom $269Free CancellationRating
6.5
2,497 reviews
Search Avianca flights
American AirlinesPriceFrom $311Free CancellationRating
7.2
11,215 reviews
Search American Airlines flights
ArajetPriceFrom $360Free CancellationRating
6.6
43 reviews
Search Arajet flights
Air CanadaPriceFrom $479Free CancellationRating
7.1
10,680 reviews
Search Air Canada flights
GOLPriceFrom $596Free CancellationRating
7.3
1,165 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South America?

Once all potential Chicago to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $187
Flights to Buenos Airesfrom $503
Flights to Sao Paulofrom $377
Flights to Bogotáfrom $162
Flights to Rio de Janeirofrom $474
Flights to Medellínfrom $94
Flights to Santiagofrom $371
Flights to Cartagenafrom $166
Flights to Quitofrom $284
Flights to Guayaquilfrom $165
Flights to Cuscofrom $320
Flights to Califrom $187