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Cheap flights from Chicago to South America
Easily compare round-trip flights from Chicago to South America
Below you can see the best fares for your round-trip flight route over the next three months. All fares were found on momondo this week. Browse the quickest and cheapest flights from Chicago to South America by changing tabs
Quickest
Cheapest
Spirit Airlines
21 Jan
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 19m
1 Stop
7:19 am
+1
CTG
Cartagena Rafael Nunez airport
28 Jan
CTG
12:00 am
Cartagena Rafael Nunez airport
10h 29m
1 Stop
9:29 am
ORD
Chicago O'Hare Intl airport
272 USD
Spirit Airlines
15 Nov
ORD
11:00 pm
Chicago O'Hare Intl airport
18h 45m
1 Stop
6:45 pm
+1
BOG
Bogotá El Dorado airport
20 Nov
BOG
12:00 am
Bogotá El Dorado airport
9h 26m
1 Stop
8:26 am
ORD
Chicago O'Hare Intl airport
320 USD
Spirit Airlines
27 Jan
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 59m
1 Stop
7:59 am
+1
BOG
Bogotá El Dorado airport
31 Jan
BOG
12:00 am
Bogotá El Dorado airport
18h 35m
1 Stop
5:35 pm
ORD
Chicago O'Hare Intl airport
330 USD
Spirit Airlines
06 Dec
ORD
11:00 pm
Chicago O'Hare Intl airport
21h 29m
2 Stops
9:29 pm
+1
CTG
Cartagena Rafael Nunez airport
10 Dec
CTG
12:00 am
Cartagena Rafael Nunez airport
20h 23m
1 Stop
7:23 pm
ORD
Chicago O'Hare Intl airport
349 USD
Spirit Airlines
02 Nov
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 31m
1 Stop
6:31 am
+1
CTG
Cartagena Rafael Nunez airport
05 Nov
CTG
12:00 am
Cartagena Rafael Nunez airport
11h 24m
1 Stop
10:24 am
ORD
Chicago O'Hare Intl airport
360 USD
Interjet
29 Feb
ORD
11:00 pm
Chicago O'Hare Intl airport
27h 47m
2 Stops
3:47 am
+2
CTG
Cartagena Rafael Nunez airport
06 Mar
CTG
12:00 am
Cartagena Rafael Nunez airport
18h 56m
2 Stops
5:56 pm
ORD
Chicago O'Hare Intl airport
365 USD
Spirit Airlines
21 Jan
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 19m
1 Stop
7:19 am
+1
CTG
Cartagena Rafael Nunez airport
28 Jan
CTG
12:00 am
Cartagena Rafael Nunez airport
10h 29m
1 Stop
9:29 am
ORD
Chicago O'Hare Intl airport
272 USD
Spirit Airlines
02 Nov
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 31m
1 Stop
6:31 am
+1
CTG
Cartagena Rafael Nunez airport
05 Nov
CTG
12:00 am
Cartagena Rafael Nunez airport
11h 24m
1 Stop
10:24 am
ORD
Chicago O'Hare Intl airport
360 USD
Spirit Airlines
02 Nov
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 31m
1 Stop
6:31 am
+1
CTG
Cartagena Rafael Nunez airport
09 Nov
CTG
12:00 am
Cartagena Rafael Nunez airport
11h 24m
1 Stop
10:24 am
ORD
Chicago O'Hare Intl airport
373 USD
Delta
12 Oct
ORD
11:00 pm
Chicago O'Hare Intl airport
8h 37m
1 Stop
7:37 am
+1
UIO
Quito Mariscal Sucr airport
19 Oct
UIO
11:00 pm
Quito Mariscal Sucr airport
12h 38m
1 Stop
11:38 am
+1
ORD
Chicago O'Hare Intl airport
564 USD
JetBlue
04 Mar
ORD
11:00 pm
Chicago O'Hare Intl airport
9h 31m
1 Stop
9:31 am
+1
CTG
Cartagena Rafael Nunez airport
09 Mar
CTG
11:00 pm
Cartagena Rafael Nunez airport
14h 40m
1 Stop
1:40 pm
+1
ORD
Chicago O'Hare Intl airport
501 USD
Spirit Airlines
27 Jan
ORD
11:00 pm
Chicago O'Hare Intl airport
7h 59m
1 Stop
7:59 am
+1
BOG
Bogotá El Dorado airport
31 Jan
BOG
12:00 am
Bogotá El Dorado airport
18h 35m
1 Stop
5:35 pm
ORD
Chicago O'Hare Intl airport
330 USD
Alternative routes for Chicago to South America
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*Flight prices to South America are based on prices for economy tickets found by momondo users during searches within the last 72 hours. These prices may no longer be available.