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Cheap flights from Chicago to Mayagüez from $345

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Mayagüez departing on 2/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:17 pm - 9:42 am
ORD
-
MAZ
19h 25m
1 stop
Multiple Airlines Logo
4:36 pm - 10:38 am
MAZ
-
ORD
44h 02m
2 stops
$345Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
12:17 pm - 9:42 am
ORD
-
MAZ
19h 25m
1 stop
Multiple Airlines Logo
10:07 am - 3:48 pm
MAZ
-
ORD
7h 41m
1 stop
$364Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
5:15 am - 6:43 pm
ORD
-
MAZ
11h 28m
2 stops
Multiple Airlines Logo
10:07 am - 12:40 am
MAZ
-
ORD
16h 33m
2 stops
$388Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
8:56 pm - 9:42 am
ORD
-
MAZ
11h 46m
1 stop
Multiple Airlines Logo
1:19 pm - 6:05 pm
MAZ
-
ORD
29h 46m
2 stops
$404Multiple Airlines
Sat, Apr 11 - Thu, Apr 16
Multiple Airlines Logo
8:56 pm - 9:42 am
ORD
-
MAZ
11h 46m
1 stop
Multiple Airlines Logo
10:07 am - 4:37 pm
MAZ
-
ORD
7h 30m
1 stop
$422Multiple Airlines
Sat, Apr 11 - Thu, Apr 16
Multiple Airlines Logo
7:00 am - 6:43 pm
ORD
-
MAZ
9h 43m
2 stops
Multiple Airlines Logo
10:07 am - 9:22 am
MAZ
-
ORD
25h 15m
3 stops
$463Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
7:00 am - 9:42 am
ORD
-
MAZ
24h 42m
3 stops
Multiple Airlines Logo
10:07 am - 9:22 am
MAZ
-
ORD
25h 15m
3 stops
$548Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
United Airlines Logo
9:15 pm - 4:11 pm
ORD
-
MAZ
17h 56m
2 stops
United Airlines Logo
1:19 pm - 8:20 pm
MAZ
-
ORD
8h 01m
1 stop
$1,691United Airlines
Wed, Mar 11 - Fri, Mar 20
United Airlines Logo
2:38 pm - 3:49 pm
ORD
-
MAZ
24h 11m
1 stop
United Airlines Logo
1:25 pm - 8:15 pm
MAZ
-
ORD
7h 50m
1 stop
$1,704United Airlines
Sun, Jun 7 - Sun, Jun 14
United Airlines Logo
9:40 pm - 3:49 pm
ORD
-
MAZ
17h 09m
2 stops
United Airlines Logo
1:25 pm - 8:15 pm
MAZ
-
ORD
7h 50m
1 stop
$1,708United Airlines
Sun, Jun 7 - Sun, Jun 14

United Airlines flights from Chicago to Mayagüez

Our best United Airlines deals on Chicago to Mayagüez flight tickets
United Airlines
Mar 11
ORD9:15 pmChicago O'Hare Intl
17h 56m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Mar 20
MAZ1:19 pmMayagüez Eugenio M De Hostos
8h 01m
1 stop
ORD8:20 pmChicago O'Hare Intl
$1,691
United Airlines
Jul 22
ORD6:18 pmChicago O'Hare Intl
20h 31m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Aug 4
MAZ1:25 pmMayagüez Eugenio M De Hostos
7h 50m
1 stop
ORD8:15 pmChicago O'Hare Intl
$1,702
United Airlines
Jun 7
ORD2:38 pmChicago O'Hare Intl
24h 11m
1 stop
MAZ3:49 pmMayagüez Eugenio M De Hostos
Jun 14
MAZ1:25 pmMayagüez Eugenio M De Hostos
7h 50m
1 stop
ORD8:15 pmChicago O'Hare Intl
$1,704

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Chicago to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 2/22

12:17 pm-9:42 am

1 stop19h 25m

Mayagüez Eugenio M De Hostos

Thu 2/26

4:36 pm-10:38 am

2 stops44h 02m

$345

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 2/22

12:17 pm-9:42 am

1 stop19h 25m

Mayagüez Eugenio M De Hostos

Thu 2/26

10:07 am-3:48 pm

1 stop7h 41m

$364

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 2/22

5:15 am-6:43 pm

2 stops11h 28m

Mayagüez Eugenio M De Hostos

Thu 2/26

10:07 am-12:40 am

2 stops16h 33m

$388

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sat 4/11

8:56 pm-9:42 am

1 stop11h 46m

Mayagüez Eugenio M De Hostos

Thu 4/16

1:19 pm-6:05 pm

2 stops29h 46m

$404

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sat 4/11

8:56 pm-9:42 am

1 stop11h 46m

Mayagüez Eugenio M De Hostos

Thu 4/16

10:07 am-4:37 pm

1 stop7h 30m

$422

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 2/22

7:00 am-6:43 pm

2 stops9h 43m

Mayagüez Eugenio M De Hostos

Thu 2/26

10:07 am-9:22 am

3 stops25h 15m

$463

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 2/22

7:00 am-9:42 am

3 stops24h 42m

Mayagüez Eugenio M De Hostos

Thu 2/26

10:07 am-9:22 am

3 stops25h 15m

$548

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Wed 3/11

9:15 pm-4:11 pm

2 stops17h 56m

Mayagüez Eugenio M De Hostos

Fri 3/20

1:19 pm-8:20 pm

1 stop8h 01m

$1,691

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 6/7

2:38 pm-3:49 pm

1 stop24h 11m

Mayagüez Eugenio M De Hostos

Sun 6/14

1:25 pm-8:15 pm

1 stop7h 50m

$1,704

ChicagoMayagüez

ORD - MAZ

ORDMAZ

Chicago O'Hare Intl

Sun 6/7

9:40 pm-3:49 pm

2 stops17h 09m

Mayagüez Eugenio M De Hostos

Sun 6/14

1:25 pm-8:15 pm

1 stop7h 50m

$1,708

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Mayagüez from

How to get the cheapest flight ticket from Chicago to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

Spirit Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Mayagüez from Chicago according to our data. Spirit Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Mayagüez (CHI to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Mayagüez

Fastest flight time

19h 25m

Direct flights

None
The fastest flight from Chicago to Mayagüez takes 19h 25m
There are no direct flights from Chicago to Mayagüez. There are no popular flight routes from Chicago to Mayagüez.
Search flight deals

  • How far is Chicago to Mayagüez Eugenio M De Hostos by plane?

    The distance between Chicago and Mayagüez Eugenio M De Hostos is about 2030.9 mi. Typically, this will take 19h 25m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Chicago to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Chicago to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to Mayagüez for you.

Can I find flights from Chicago to Mayagüez with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mayagüez from Chicago with this policy.

How can momondo help me find flights from Chicago to Mayagüez?

momondo helps you find the best flight between Chicago and Mayagüez by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Mayagüez right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Mayagüez now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mayagüez and let you know when they change.

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