Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Charlotte to Knoxville from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Knoxville departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charlotte to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:46 am - 10:04 amCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
24h 18m1 stop Fort Lauderdale
Multiple Airlines Logo
2:49 pm - 8:01 amTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
17h 12m1 stop Orlando
$236Multiple Airlines
Sat, Aug 29 - Mon, Aug 31
Multiple Airlines Logo
9:46 am - 1:04 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
27h 18m1 stop Fort Lauderdale
Multiple Airlines Logo
2:49 pm - 8:01 amTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
17h 12m1 stop Orlando
$240Multiple Airlines
Fri, Aug 28 - Mon, Aug 31
Multiple Airlines Logo
10:02 pm - 12:14 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
14h 12m1 stop Orlando
Multiple Airlines Logo
6:00 am - 1:47 pmTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
7h 47m1 stop Washington, D.C. Dulles Intl
$250Multiple Airlines
Thu, Oct 22 - Sun, Oct 25
Multiple Airlines Logo
9:46 am - 10:04 amCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
24h 18m1 stop Fort Lauderdale
Multiple Airlines Logo
2:49 pm - 8:01 amTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
17h 12m1 stop Orlando
$259Multiple Airlines
Tue, Aug 25 - Mon, Aug 31
Multiple Airlines Logo
9:40 pm - 8:39 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
22h 59m1 stop Orlando
Multiple Airlines Logo
6:55 pm - 7:55 pmTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
25h 00m1 stop Fort Lauderdale
$267Multiple Airlines
Sun, Sep 13 - Sat, Sep 19
Southwest Logo
1:30 pm - 7:55 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
6h 25m1 stop Baltimore/Washington
Southwest Logo
5:45 pm - 9:55 pmTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
4h 10m1 stop Nashville Intl
$269Southwest
Wed, Sep 9 - Thu, Sep 10
Multiple Airlines Logo
9:46 am - 10:04 amCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
24h 18m1 stop Fort Lauderdale
Multiple Airlines Logo
2:49 pm - 8:01 amTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
17h 12m1 stop Orlando
$269Multiple Airlines
Wed, Aug 26 - Mon, Aug 31
Southwest Logo
1:30 pm - 7:55 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
6h 25m1 stop Baltimore/Washington
Southwest Logo
7:10 am - 5:35 pmTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
10h 25m2 stops Nashville Intl Lambert-St Louis
$280Southwest
Wed, Sep 9 - Thu, Sep 10
American Airlines Logo
9:23 am - 7:01 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
9h 38m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:16 pm - 6:23 amTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
12h 07m1 stop Washington, D.C. Reagan-National
$421American Airlines
Wed, Sep 2 - Wed, Sep 9
American Airlines Logo
7:49 am - 5:36 pmCLT  Charlotte Douglas-TYS Knoxville McGhee Tyson
9h 47m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:16 pm - 8:55 pmTYS  Knoxville McGhee Tyson-CLT Charlotte Douglas
26h 39m1 stop Washington, D.C. Reagan-National
$421American Airlines
Sat, Sep 12 - Mon, Sep 14

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Southwest flights from Charlotte to Knoxville

Our best Southwest deals on Charlotte to Knoxville flight tickets
Southwest
Sep 9
CLT1:30 pmCharlotte Douglas
6h 25m
1 stop
TYS7:55 pmKnoxville McGhee Tyson
Sep 10
TYS7:10 amKnoxville McGhee Tyson
10h 25m
2 stops
CLT5:35 pmCharlotte Douglas
$280
Southwest
Dec 3
CLT1:30 pmCharlotte Douglas
7h 15m
1 stop
TYS8:45 pmKnoxville McGhee Tyson
Dec 7
TYS7:55 amKnoxville McGhee Tyson
6h 30m
1 stop
CLT2:25 pmCharlotte Douglas
$318
Southwest
Oct 20
CLT1:10 pmCharlotte Douglas
7h 50m
2 stops
TYS9:00 pmKnoxville McGhee Tyson
Oct 24
TYS6:40 amKnoxville McGhee Tyson
6h 25m
1 stop
CLT1:05 pmCharlotte Douglas
$352

American Airlines flights from Charlotte to Knoxville

Our best American Airlines deals on Charlotte to Knoxville flight tickets
American Airlines
Sep 2
CLT9:23 amCharlotte Douglas
9h 38m
1 stop
TYS7:01 pmKnoxville McGhee Tyson
Sep 9
TYS6:16 pmKnoxville McGhee Tyson
12h 07m
1 stop
CLT6:23 amCharlotte Douglas
$421
American Airlines
Aug 14
CLT7:45 pmCharlotte Douglas
1h 14m
TYS8:59 pmKnoxville McGhee Tyson
Aug 16
TYS6:05 pmKnoxville McGhee Tyson
1h 28m
CLT7:33 pmCharlotte Douglas
$525
American Airlines
Aug 19
CLT12:15 pmCharlotte Douglas
1h 16m
TYS1:31 pmKnoxville McGhee Tyson
Aug 25
TYS6:05 pmKnoxville McGhee Tyson
1h 28m
CLT7:33 pmCharlotte Douglas
$571

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Charlotte to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Sat 8/29

9:46 am-10:04 am

1 stop24h 18m

Knoxville McGhee Tyson

Mon 8/31

2:49 pm-8:01 am

1 stop17h 12m

$236

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Fri 8/28

9:46 am-1:04 pm

1 stop27h 18m

Knoxville McGhee Tyson

Mon 8/31

2:49 pm-8:01 am

1 stop17h 12m

$240

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Thu 10/22

10:02 pm-12:14 pm

1 stop14h 12m

Knoxville McGhee Tyson

Sun 10/25

6:00 am-1:47 pm

1 stop7h 47m

$250

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Tue 8/25

9:46 am-10:04 am

1 stop24h 18m

Knoxville McGhee Tyson

Mon 8/31

2:49 pm-8:01 am

1 stop17h 12m

$259

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Sun 9/13

9:40 pm-8:39 pm

1 stop22h 59m

Knoxville McGhee Tyson

Sat 9/19

6:55 pm-7:55 pm

1 stop25h 00m

$267
Quickest round-trip

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Wed 9/9

1:30 pm-7:55 pm

1 stop6h 25m

Knoxville McGhee Tyson

Thu 9/10

5:45 pm-9:55 pm

1 stop4h 10m

$269

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Wed 8/26

9:46 am-10:04 am

1 stop24h 18m

Knoxville McGhee Tyson

Mon 8/31

2:49 pm-8:01 am

1 stop17h 12m

$269

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Wed 9/9

1:30 pm-7:55 pm

1 stop6h 25m

Knoxville McGhee Tyson

Thu 9/10

7:10 am-5:35 pm

2 stops10h 25m

$280

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Wed 9/2

9:23 am-7:01 pm

1 stop9h 38m

Knoxville McGhee Tyson

Wed 9/9

6:16 pm-6:23 am

1 stop12h 07m

$421

CharlotteKnoxville

CLT Charlotte Douglas - TYS Knoxville McGhee Tyson

CLTTYS

Charlotte Douglas

Sat 9/12

7:49 am-5:36 pm

1 stop9h 47m

Knoxville McGhee Tyson

Mon 9/14

6:16 pm-8:55 pm

1 stop26h 39m

$421

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Charlotte to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Charlotte, with most prices found around $0. If you aren’t able to travel during the month of August, then book flights to Knoxville from Charlotte during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $226.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Charlotte to Knoxville is on a Sunday. Travelers who choose to depart for Knoxville on a Sunday will often find tickets for as low as $555. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to Knoxville for around $715.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Charlotte to Knoxville when you can find flight prices for as low as $545. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $749.

What is the cheapest Charlotte Douglas to Knoxville McGhee Tyson flight route?

Fly from Charlotte Douglas to Knoxville McGhee Tyson for the best Charlotte Douglas - Knoxville McGhee Tyson flight prices

What cabin class options are available on Charlotte to Knoxville flights?

There is only 1 cabin class available to choose from on Charlotte to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charlotte to Knoxville flights?

You could potentially save up to 14% on your flight if you consider stops on a Charlotte to Knoxville flight.

How have Charlotte to Knoxville flight prices changed over time?

As of August 2026, prices for Charlotte to Knoxville flights are approximately 327% more expensive when compared to flights at the same time last year.

When to book flights from Charlotte to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Knoxville (CLT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Knoxville

Fastest flight time

1h 13m

Direct flights

Wed, Thu, Fri, Sat and Sun

Airports in Knoxville

1 airport
The fastest flight from Charlotte to Knoxville takes 1h 13m
Direct flights go from Charlotte to Knoxville on Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is American Airlines.
There is 1 airport in Knoxville. From Charlotte there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Charlotte to Knoxville

  • How far is Charlotte Douglas to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 180.1 mi away from Charlotte Douglas. 1h 13m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Charlotte to Knoxville?

  • What is the most popular airline from Charlotte to Knoxville?

Best airlines flying from Charlotte to Knoxville

Compare and see reviews for airlines that fly from Charlotte to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $487Free CancellationRating
7.1
11,899 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Knoxville

    American Airlines operates around 53 flights from Charlotte to Knoxville every week. The average price of these flights found in the last 72 hours has been $555, but momondo users have found American Airlines deals from Charlotte to Knoxville from as low as $487 round-trip. American Airlines has been scored 7.1/10 in 11,898 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Knoxville?

Finding the right flight to Knoxville from Charlotte is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Charlotte to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Charlotte with this policy.

How can momondo help me find flights from Charlotte to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Charlotte.

I’m not ready to book a flight from Charlotte to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 9/9
Wed 9/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States