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Cheap flights from Charlotte to Knoxville from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Knoxville departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charlotte to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:13 pm - 10:10 am
CLT
-
TYS
14h 57m
1 stop
Multiple Airlines Logo
9:43 pm - 8:21 am
TYS
-
CLT
10h 38m
1 stop
$254Multiple Airlines
Mon, Mar 9 - Sun, Mar 15
Multiple Airlines Logo
1:24 pm - 11:26 pm
CLT
-
TYS
10h 02m
1 stop
Multiple Airlines Logo
9:43 pm - 8:21 am
TYS
-
CLT
10h 38m
1 stop
$256Multiple Airlines
Sun, Mar 8 - Sun, Mar 15
Multiple Airlines Logo
7:13 pm - 10:10 am
CLT
-
TYS
14h 57m
1 stop
Multiple Airlines Logo
2:06 pm - 2:17 pm
TYS
-
CLT
24h 11m
1 stop
$258Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Southwest Logo
6:40 am - 12:00 pm
CLT
-
TYS
5h 20m
1 stop
Southwest Logo
5:50 pm - 9:40 pm
TYS
-
CLT
3h 50m
1 stop
$261Southwest
Tue, Apr 14 - Wed, Apr 15
Southwest Logo
6:40 am - 12:00 pm
CLT
-
TYS
5h 20m
1 stop
Southwest Logo
7:05 am - 5:40 pm
TYS
-
CLT
10h 35m
2 stops
$266Southwest
Tue, Apr 14 - Wed, Apr 15
Multiple Airlines Logo
7:48 pm - 11:01 am
CLT
-
TYS
15h 13m
2 stops
Multiple Airlines Logo
9:43 pm - 8:21 am
TYS
-
CLT
10h 38m
1 stop
$268Multiple Airlines
Sun, Mar 8 - Sun, Mar 15
Multiple Airlines Logo
7:13 pm - 9:40 am
CLT
-
TYS
14h 27m
1 stop
Multiple Airlines Logo
9:42 pm - 8:26 am
TYS
-
CLT
10h 44m
1 stop
$273Multiple Airlines
Fri, Mar 6 - Sun, Mar 8
Multiple Airlines Logo
7:13 pm - 9:40 am
CLT
-
TYS
14h 27m
1 stop
Multiple Airlines Logo
7:20 am - 8:51 pm
TYS
-
CLT
13h 31m
1 stop
$281Multiple Airlines
Fri, Mar 6 - Sun, Mar 8
Multiple Airlines Logo
10:58 pm - 12:51 pm
CLT
-
TYS
37h 53m
2 stops
Multiple Airlines Logo
9:43 pm - 8:21 am
TYS
-
CLT
10h 38m
1 stop
$283Multiple Airlines
Mon, Mar 9 - Sun, Mar 15
Multiple Airlines Logo
10:58 pm - 12:51 pm
CLT
-
TYS
37h 53m
2 stops
Multiple Airlines Logo
2:06 pm - 2:17 pm
TYS
-
CLT
24h 11m
1 stop
$287Multiple Airlines
Mon, Mar 9 - Mon, Mar 16

American Airlines flights from Charlotte to Knoxville

Our best American Airlines deals on Charlotte to Knoxville flight tickets
American Airlines
Feb 19
CLT9:20 amCharlotte Douglas
12h 18m
1 stop
TYS9:38 pmKnoxville McGhee Tyson
Feb 24
TYS6:05 amKnoxville McGhee Tyson
9h 17m
1 stop
CLT3:22 pmCharlotte Douglas
$361
American Airlines
Mar 9
CLT4:13 pmCharlotte Douglas
23h 19m
1 stop
TYS3:32 pmKnoxville McGhee Tyson
Mar 16
TYS11:18 amKnoxville McGhee Tyson
10h 06m
1 stop
CLT9:24 pmCharlotte Douglas
$395
American Airlines
Mar 6
CLT8:39 pmCharlotte Douglas
19h 10m
1 stop
TYS3:49 pmKnoxville McGhee Tyson
Mar 8
TYS6:05 amKnoxville McGhee Tyson
9h 14m
1 stop
CLT3:19 pmCharlotte Douglas
$456

Southwest flights from Charlotte to Knoxville

Our best Southwest deals on Charlotte to Knoxville flight tickets
Southwest
Apr 14
CLT6:40 amCharlotte Douglas
5h 20m
1 stop
TYS12:00 pmKnoxville McGhee Tyson
Apr 15
TYS5:50 pmKnoxville McGhee Tyson
3h 50m
1 stop
CLT9:40 pmCharlotte Douglas
$261
Southwest
Apr 14
CLT6:40 amCharlotte Douglas
5h 20m
1 stop
TYS12:00 pmKnoxville McGhee Tyson
Apr 15
TYS7:05 amKnoxville McGhee Tyson
10h 35m
2 stops
CLT5:40 pmCharlotte Douglas
$266
Southwest
May 8
CLT6:15 amCharlotte Douglas
5h 25m
1 stop
TYS11:40 amKnoxville McGhee Tyson
May 11
TYS6:45 pmKnoxville McGhee Tyson
3h 45m
1 stop
CLT10:30 pmCharlotte Douglas
$290

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Charlotte to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Mon 3/9

7:13 pm-10:10 am

1 stop14h 57m

Knoxville McGhee Tyson

Sun 3/15

9:43 pm-8:21 am

1 stop10h 38m

$254

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Sun 3/8

1:24 pm-11:26 pm

1 stop10h 02m

Knoxville McGhee Tyson

Sun 3/15

9:43 pm-8:21 am

1 stop10h 38m

$256

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Mon 3/9

7:13 pm-10:10 am

1 stop14h 57m

Knoxville McGhee Tyson

Mon 3/16

2:06 pm-2:17 pm

1 stop24h 11m

$258

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Tue 4/14

6:40 am-12:00 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 4/15

5:50 pm-9:40 pm

1 stop3h 50m

$261

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Tue 4/14

6:40 am-12:00 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 4/15

7:05 am-5:40 pm

2 stops10h 35m

$266

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Sun 3/8

7:48 pm-11:01 am

2 stops15h 13m

Knoxville McGhee Tyson

Sun 3/15

9:43 pm-8:21 am

1 stop10h 38m

$268

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Fri 3/6

7:13 pm-9:40 am

1 stop14h 27m

Knoxville McGhee Tyson

Sun 3/8

9:42 pm-8:26 am

1 stop10h 44m

$273

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Fri 3/6

7:13 pm-9:40 am

1 stop14h 27m

Knoxville McGhee Tyson

Sun 3/8

7:20 am-8:51 pm

1 stop13h 31m

$281

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Mon 3/9

10:58 pm-12:51 pm

2 stops37h 53m

Knoxville McGhee Tyson

Sun 3/15

9:43 pm-8:21 am

1 stop10h 38m

$283

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Mon 3/9

10:58 pm-12:51 pm

2 stops37h 53m

Knoxville McGhee Tyson

Mon 3/16

2:06 pm-2:17 pm

1 stop24h 11m

$287

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Charlotte to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Charlotte to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $519. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to Knoxville for around $571.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Charlotte to Knoxville when you can find flight prices for as low as $544. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $549.

What is the cheapest Charlotte Douglas to Knoxville McGhee Tyson flight route?

Fly from Charlotte Douglas to Knoxville McGhee Tyson for the best Charlotte Douglas - Knoxville McGhee Tyson flight prices

What cabin class options are available on Charlotte Douglas to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Charlotte Douglas to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Charlotte to Knoxville flight prices changed over time?

As of January 2026, prices for Charlotte to Knoxville flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Charlotte to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Knoxville (CLT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Knoxville

Fastest flight time

1h 20m

Direct flights

Every day

Airports in Knoxville

1 airport
The fastest flight from Charlotte to Knoxville takes 1h 20m
Direct flights go from Charlotte to Knoxville every day.
There is 1 airport in Knoxville. From Charlotte there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Charlotte Douglas to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 180.1 mi away from Charlotte Douglas. 1h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charlotte Douglas Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Charlotte to Knoxville?

  • What is the most popular airline from Charlotte to Knoxville?

Best airlines flying from Charlotte to Knoxville

Compare and see reviews for airlines that fly from Charlotte to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $482Free CancellationRating
7.2
11,201 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Knoxville

    American Airlines operates around 18 flights from Charlotte to Knoxville every week. The average price of these flights found in the last 72 hours has been $547, but momondo users have found American Airlines deals from Charlotte to Knoxville from as low as $482 round-trip. American Airlines has been scored 7.2/10 in 11,201 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Murphy
Alcoa
Maryville
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Knoxville?

Finding the right flight to Knoxville from Charlotte is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Charlotte to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Charlotte with this policy.

How can momondo help me find flights from Charlotte to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Charlotte.

I’m not ready to book a flight from Charlotte to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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