What is the cheapest airline that flies from Buffalo to Panama?

United Airlines is the most popular carrier operating from Buffalo to Panama

When did momondo last update prices for flights from Buffalo Airport to Panama?

Prices for flights from Buffalo Airport to Panama were last updated today.

How many operators does momondo search for flights from Buffalo Airport to Panama?

As of September 2025, there are 2 operators available to choose from for flights from Buffalo Airport to Panama.

How old do you have to be to fly from Buffalo Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$226 Cheap Flights from Buffalo to Panama in 2025

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Find the cheapest flights from Buffalo to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

6:30 am - 1:50 pmBUF-PTY

8h 20m1 stop

3:30 pm - 4:52 pmPTY-BUF

24h 22m2 stops

$522United Airlines

Find Deal

Mon, Sep 15 - Thu, Sep 18

7:29 pm - 2:31 pmBUF-PTY

20h 02m2 stops

3:31 pm - 3:58 pmPTY-BUF

23h 27m2 stops

$527American Airlines

Find Deal

Sun, Sep 21 - Sun, Sep 28

6:00 am - 12:55 pmBUF-PTY

7h 55m1 stop

2:10 pm - 11:37 pmPTY-BUF

8h 27m1 stop

$544Delta

Find Deal

Tue, Sep 23 - Tue, Sep 30

5:55 pm - 2:14 pmBUF-PTY

21h 19m2 stops

3:30 pm - 4:53 pmPTY-BUF

24h 23m2 stops

$549United Airlines

Find Deal

Tue, Oct 14 - Tue, Oct 21

6:00 am - 12:56 pmBUF-PTY

7h 56m1 stop

2:21 pm - 11:39 pmPTY-BUF

8h 18m1 stop

$627Delta

Find Deal

Wed, Oct 15 - Wed, Oct 22

6:30 am - 1:50 pmBUF-PTY

8h 20m1 stop

3:30 pm - 4:53 pmPTY-BUF

24h 23m2 stops

$632United Airlines

Find Deal

Sun, Sep 21 - Sun, Sep 28

6:00 am - 1:55 pmBUF-PTY

7h 55m1 stop

3:27 pm - 11:57 pmPTY-BUF

8h 30m1 stop

$689Delta

Find Deal

Sat, Jan 3 - Tue, Feb 3

6:00 am - 12:55 pmBUF-PTY

7h 55m1 stop

2:10 pm - 11:37 pmPTY-BUF

8h 27m1 stop

$812Delta

Find Deal

Sun, Sep 21 - Sun, Sep 28

8:00 pm - 12:35 pmBUF-PTY

17h 35m3 stops

3:25 am - 9:13 pmPTY-BUF

16h 48m2 stops

$887Avianca

Find Deal

Tue, Sep 23 - Mon, Sep 29

8:00 pm - 10:25 amBUF-PTY

15h 25m2 stops

3:25 am - 9:13 pmPTY-BUF

16h 48m2 stops

$905Avianca

Find Deal

Tue, Sep 23 - Mon, Sep 29

United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

United Airlines

Sep 15

BUF6:30 amBuffalo

8h 20m

1 stop

PTY1:50 pmPanama City Tocumen Intl

Sep 18

PTY3:30 pmPanama City Tocumen Intl

24h 22m

2 stops

BUF4:52 pmBuffalo

$522

Find similar

United Airlines

Oct 14

BUF5:55 pmBuffalo

21h 19m

2 stops

PTY2:14 pmPanama City Tocumen Intl

Oct 21

PTY3:30 pmPanama City Tocumen Intl

24h 23m

2 stops

BUF4:53 pmBuffalo

$549

Find similar

United Airlines

Sep 21

BUF6:30 amBuffalo

8h 20m

1 stop

PTY1:50 pmPanama City Tocumen Intl

Sep 28

PTY3:30 pmPanama City Tocumen Intl

24h 23m

2 stops

BUF4:53 pmBuffalo

$632

Find similar

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

Delta

Sep 23

BUF6:00 amBuffalo

7h 55m

1 stop

PTY12:55 pmPanama City Tocumen Intl

Sep 30

PTY2:10 pmPanama City Tocumen Intl

8h 27m

1 stop

BUF11:37 pmBuffalo

$544

Find similar

Delta

Oct 15

BUF6:00 amBuffalo

7h 56m

1 stop

PTY12:56 pmPanama City Tocumen Intl

Oct 22

PTY2:21 pmPanama City Tocumen Intl

8h 18m

1 stop

BUF11:39 pmBuffalo

$627

Find similar

Delta

Jan 3

BUF6:00 amBuffalo

7h 55m

1 stop

PTY1:55 pmPanama City Tocumen Intl

Feb 3

PTY3:27 pmPanama City Tocumen Intl

8h 30m

1 stop

BUF11:57 pmBuffalo

$689

Find similar

Fly from

Fly to

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 9/15

6:30 am-1:50 pm

1 stop8h 20m

Panama City Tocumen Intl

Thu 9/18

3:30 pm-4:52 pm

2 stops24h 22m

$522

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 9/21

7:29 pm-2:31 pm

2 stops20h 02m

Panama City Tocumen Intl

Sun 9/28

3:31 pm-3:58 pm

2 stops23h 27m

$527

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 9/23

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 9/30

2:10 pm-11:37 pm

1 stop8h 27m

$544

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 10/14

5:55 pm-2:14 pm

2 stops21h 19m

Panama City Tocumen Intl

Tue 10/21

3:30 pm-4:53 pm

2 stops24h 23m

$549

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 10/15

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Wed 10/22

2:21 pm-11:39 pm

1 stop8h 18m

$627

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 9/21

6:30 am-1:50 pm

1 stop8h 20m

Panama City Tocumen Intl

Sun 9/28

3:30 pm-4:53 pm

2 stops24h 23m

$632

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 1/3

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 2/3

3:27 pm-11:57 pm

1 stop8h 30m

$689

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 9/21

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 9/28

2:10 pm-11:37 pm

1 stop8h 27m

$812

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 9/23

8:00 pm-12:35 pm

3 stops17h 35m

Panama City Tocumen Intl

Mon 9/29

3:25 am-9:13 pm

2 stops16h 48m

$887

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 9/23

8:00 pm-10:25 am

2 stops15h 25m

Panama City Tocumen Intl

Mon 9/29

3:25 am-9:13 pm

2 stops16h 48m

$905

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Panama?

According to our data, Friday is the cheapest day to fly to Panama from Buffalo. The lowest ticket price found for a Friday departure recently was $480. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Buffalo to Panama for around $760.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Buffalo to Panama when you can find flight prices for as low as $386. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $628 per ticket.

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 67% on your flight if you consider stops on a Buffalo to Panama flight.

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Direct flights	None

There are no direct flights from Buffalo to Panama. There are no popular flight routes from Buffalo to Panama.

Search flight deals

When did momondo last update prices for flights from Buffalo Airport to Panama?
Prices for flights from Buffalo Airport to Panama were last updated today.
How many operators does momondo search for flights from Buffalo Airport to Panama?
As of September 2025, there are 2 operators available to choose from for flights from Buffalo Airport to Panama.
How old do you have to be to fly from Buffalo Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $441	Free Cancellation	Rating 7.4 8,936 reviews		Search United Airlines flights
Delta	PriceFrom $445	Free Cancellation	Rating 7.9 7,974 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Buffalo.

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

Flights from Buffalo to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Buffalo.

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Panama

Popular cities in Panama

Flights to Panama Cityfrom $272

Flights to Bocas del Torofrom $589

Flights to Davidfrom $296

Flights to Changuinola

Cheap flights from Buffalo to Panama from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Buffalo to Panama

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

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Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

See travel insights to Panama from

How to get the cheapest flight ticket from Buffalo to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

What is the cheapest time of day to depart on your flight to Panama?

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 67% on your flight if you consider stops on a Buffalo to Panama flight.

What is the cheapest airline that flies from Buffalo to Panama?

United Airlines is the most popular carrier operating from Buffalo to Panama

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Direct flights

When did momondo last update prices for flights from Buffalo Airport to Panama?

How many operators does momondo search for flights from Buffalo Airport to Panama?

How old do you have to be to fly from Buffalo Airport to Panama?

What documentation or ID do you need to fly to Panama?

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Buffalo to Panama?

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo