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Cheap flights from Buffalo to Panama from $555

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama departing on 10/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:00 pm - 10:30 am
BUF
-
PTY
15h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 8:24 am
PTY
-
BUF
15h 34m
2 stops
$555Multiple Airlines
Fri, Oct 16 - Thu, Oct 22
Multiple Airlines Logo
3:55 pm - 10:30 am
BUF
-
PTY
19h 35m
2 stops
Multiple Airlines Logo
3:50 pm - 7:52 am
PTY
-
BUF
15h 02m
2 stops
$570Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
4:00 pm - 2:55 pm
BUF
-
PTY
23h 55m
3 stops
Multiple Airlines Logo
3:50 pm - 3:01 pm
PTY
-
BUF
22h 11m
2 stops
$576Multiple Airlines
Fri, Oct 16 - Thu, Oct 22
Multiple Airlines Logo
8:06 pm - 10:30 am
BUF
-
PTY
39h 24m
2 stops
Multiple Airlines Logo
3:50 pm - 7:10 pm
PTY
-
BUF
26h 20m
2 stops
$635Multiple Airlines
Sat, Aug 1 - Sat, Aug 8
Multiple Airlines Logo
7:21 pm - 2:55 pm
BUF
-
PTY
20h 34m
3 stops
Multiple Airlines Logo
11:25 am - 8:24 am
PTY
-
BUF
19h 59m
3 stops
$650Multiple Airlines
Fri, Jul 24 - Wed, Sep 23
Delta Logo
6:00 am - 12:56 pm
BUF
-
PTY
7h 56m
1 stop
Delta Logo
2:21 pm - 10:38 am
PTY
-
BUF
19h 17m
2 stops
$664Delta
Thu, Oct 15 - Tue, Oct 20
United Airlines Logo
6:00 am - 8:02 pm
BUF
-
PTY
14h 02m
1 stop
United Airlines Logo
10:00 am - 10:37 pm
PTY
-
BUF
12h 37m
1 stop
$673United Airlines
Mon, Nov 23 - Thu, Dec 3
Delta Logo
7:43 pm - 12:56 pm
BUF
-
PTY
18h 13m
2 stops
Delta Logo
2:21 pm - 5:29 pm
PTY
-
BUF
26h 08m
2 stops
$677Delta
Wed, Oct 14 - Thu, Oct 22
United Airlines Logo
7:54 pm - 7:31 pm
BUF
-
PTY
24h 37m
1 stop
United Airlines Logo
9:45 am - 11:11 pm
PTY
-
BUF
12h 26m
1 stop
$694United Airlines
Sat, Oct 17 - Thu, Oct 22
United Airlines Logo
5:58 pm - 2:14 pm
BUF
-
PTY
21h 16m
2 stops
United Airlines Logo
3:30 pm - 9:28 am
PTY
-
BUF
16h 58m
2 stops
$697United Airlines
Mon, Aug 17 - Mon, Aug 24

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Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets
Delta
Oct 15
BUF6:00 amBuffalo
7h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 21
PTY2:21 pmPanama City Tocumen Intl
26h 29m
1 stop
BUF5:50 pmBuffalo
$664
Delta
Oct 14
BUF7:43 pmBuffalo
18h 13m
2 stops
PTY12:56 pmPanama City Tocumen Intl
Oct 22
PTY2:21 pmPanama City Tocumen Intl
26h 08m
2 stops
BUF5:29 pmBuffalo
$677
Delta
Aug 18
BUF6:05 amBuffalo
7h 50m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Aug 25
PTY2:20 pmPanama City Tocumen Intl
8h 39m
1 stop
BUF11:59 pmBuffalo
$713

United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets
United Airlines
Nov 23
BUF6:00 amBuffalo
14h 02m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Dec 3
PTY10:00 amPanama City Tocumen Intl
12h 37m
1 stop
BUF10:37 pmBuffalo
$673
United Airlines
Oct 17
BUF7:54 pmBuffalo
24h 37m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Oct 21
PTY9:45 amPanama City Tocumen Intl
12h 26m
1 stop
BUF11:11 pmBuffalo
$694
United Airlines
Aug 17
BUF7:33 pmBuffalo
9h 31m
1 stop
PTY4:04 amPanama City Tocumen Intl
Aug 24
PTY3:30 pmPanama City Tocumen Intl
20h 46m
2 stops
BUF1:16 pmBuffalo
$697

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 10/16

8:00 pm-10:30 am

2 stops15h 30m

Panama City Tocumen Intl

Thu 10/22

3:50 pm-8:24 am

2 stops15h 34m

$555

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 8/18

3:55 pm-10:30 am

2 stops19h 35m

Panama City Tocumen Intl

Tue 8/25

3:50 pm-7:52 am

2 stops15h 02m

$570

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 10/16

4:00 pm-2:55 pm

3 stops23h 55m

Panama City Tocumen Intl

Thu 10/22

3:50 pm-3:01 pm

2 stops22h 11m

$576

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 8/1

8:06 pm-10:30 am

2 stops39h 24m

Panama City Tocumen Intl

Sat 8/8

3:50 pm-7:10 pm

2 stops26h 20m

$635

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 7/24

7:21 pm-2:55 pm

3 stops20h 34m

Panama City Tocumen Intl

Wed 9/23

11:25 am-8:24 am

3 stops19h 59m

$650

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 10/15

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Tue 10/20

2:21 pm-10:38 am

2 stops19h 17m

$664
Quickest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 11/23

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Thu 12/3

10:00 am-10:37 pm

1 stop12h 37m

$673

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 10/14

7:43 pm-12:56 pm

2 stops18h 13m

Panama City Tocumen Intl

Thu 10/22

2:21 pm-5:29 pm

2 stops26h 08m

$677

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 10/17

7:54 pm-7:31 pm

1 stop24h 37m

Panama City Tocumen Intl

Thu 10/22

9:45 am-11:11 pm

1 stop12h 26m

$694

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/17

5:58 pm-2:14 pm

2 stops21h 16m

Panama City Tocumen Intl

Mon 8/24

3:30 pm-9:28 am

2 stops16h 58m

$697

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Buffalo to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Buffalo, with most prices found around $0. If you don’t want to visit Panama in August, then you should wait until March to fly from Buffalo, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 22% on your flight if you consider stops on a Buffalo to Panama flight.

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Buffalo to Panama takes 7h 55m
There are no direct flights from Buffalo to Panama. There are no popular flight routes from Buffalo to Panama.
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Frequently asked questions about flying from Buffalo to Panama

  • When did momondo last update prices for flights from Buffalo Airport to Panama?

    Prices for flights from Buffalo Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Panama?

  • How old do you have to be to fly from Buffalo Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $517Free CancellationRating
7.8
8,453 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Buffalo.

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

Flights from Buffalo to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Buffalo.

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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