What is the cheapest airline that flies from Buffalo to Panama?

American Airlines and Delta are the most popular carriers operating from Buffalo to Panama

When did momondo last update prices for flights from Buffalo Airport to Panama?

Prices for flights from Buffalo Airport to Panama were last updated today.

How many operators does momondo search for flights from Buffalo Airport to Panama?

As of January 2026, there is 1 operator available to choose from for flights from Buffalo Airport to Panama.

How old do you have to be to fly from Buffalo Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$348 Cheap Flights from Buffalo to Panama in 2026

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Find the cheapest flights from Buffalo to Panama

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:30 pm - 6:55 pm

BUF

PTY

24h 25m

2 stops

3:50 pm - 9:04 am

PTY

BUF

16h 14m

2 stops

$506Multiple Airlines

Tue, Mar 10 - Tue, Mar 17

5:27 pm - 3:52 pm

BUF

PTY

22h 25m

2 stops

2:27 pm - 11:43 am

PTY

BUF

21h 16m

2 stops

$543American Airlines

Fri, Feb 6 - Wed, Feb 11

6:55 pm - 4:04 am

BUF

PTY

10h 09m

1 stop

3:30 pm - 1:13 pm

PTY

BUF

20h 43m

2 stops

$620United Airlines

Mon, Mar 30 - Fri, Apr 3

10:21 am - 7:31 pm

BUF

PTY

10h 10m

1 stop

10:55 pm - 10:26 am

PTY

BUF

10h 31m

1 stop

$676United Airlines

Mon, Jun 8 - Sun, Jul 5

6:00 am - 1:03 pm

BUF

PTY

8h 03m

1 stop

2:28 pm - 11:46 pm

PTY

BUF

8h 18m

1 stop

$686Delta

Tue, Mar 10 - Tue, Mar 17

5:50 pm - 4:12 pm

BUF

PTY

23h 22m

2 stops

10:55 pm - 10:26 am

PTY

BUF

10h 31m

1 stop

$703United Airlines

Mon, Jun 8 - Sun, Jul 5

6:00 am - 1:55 pm

BUF

PTY

7h 55m

1 stop

3:20 pm - 11:28 pm

PTY

BUF

8h 08m

1 stop

$714Delta

Fri, Feb 6 - Wed, Feb 11

6:00 am - 1:55 pm

BUF

PTY

7h 55m

1 stop

3:20 pm - 11:28 pm

PTY

BUF

8h 08m

1 stop

$773Delta

Thu, Feb 5 - Tue, Feb 10

6:55 pm - 4:04 am

BUF

PTY

10h 09m

1 stop

10:55 pm - 10:02 am

PTY

BUF

10h 07m

1 stop

$776United Airlines

Mon, Mar 30 - Fri, Apr 3

6:00 am - 1:55 pm

BUF

PTY

7h 55m

1 stop

3:20 pm - 11:28 pm

PTY

BUF

8h 08m

1 stop

$833Delta

Fri, Feb 6 - Wed, Feb 11

United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

United Airlines

Mar 30

BUF5:55 pmBuffalo

21h 19m

2 stops

PTY2:14 pmPanama City Tocumen Intl

Apr 3

PTY3:30 pmPanama City Tocumen Intl

20h 43m

2 stops

BUF1:13 pmBuffalo

$620

United Airlines

Jun 8

BUF10:21 amBuffalo

10h 10m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Jul 5

PTY10:55 pmPanama City Tocumen Intl

10h 31m

1 stop

BUF10:26 amBuffalo

$676

United Airlines

Jun 8

BUF5:50 pmBuffalo

23h 22m

2 stops

PTY4:12 pmPanama City Tocumen Intl

Jul 5

PTY10:55 pmPanama City Tocumen Intl

10h 31m

1 stop

BUF10:26 amBuffalo

$703

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

Delta

Mar 10

BUF6:00 amBuffalo

8h 03m

1 stop

PTY1:03 pmPanama City Tocumen Intl

Mar 17

PTY2:28 pmPanama City Tocumen Intl

8h 18m

1 stop

BUF11:46 pmBuffalo

$686

Delta

Feb 6

BUF6:00 amBuffalo

7h 55m

1 stop

PTY1:55 pmPanama City Tocumen Intl

Feb 11

PTY3:20 pmPanama City Tocumen Intl

8h 08m

1 stop

BUF11:28 pmBuffalo

$714

Delta

Feb 5

BUF6:00 amBuffalo

7h 55m

1 stop

PTY1:55 pmPanama City Tocumen Intl

Feb 10

PTY3:20 pmPanama City Tocumen Intl

8h 08m

1 stop

BUF11:28 pmBuffalo

$773

Fly from

Fly to

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 3/10

7:30 pm-6:55 pm

2 stops24h 25m

Panama City Tocumen Intl

Tue 3/17

3:50 pm-9:04 am

2 stops16h 14m

$506

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 2/6

5:27 pm-3:52 pm

2 stops22h 25m

Panama City Tocumen Intl

Wed 2/11

2:27 pm-11:43 am

2 stops21h 16m

$543

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/30

6:55 pm-4:04 am

1 stop10h 09m

Panama City Tocumen Intl

Fri 4/3

3:30 pm-1:13 pm

2 stops20h 43m

$620

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 6/8

10:21 am-7:31 pm

1 stop10h 10m

Panama City Tocumen Intl

Sun 7/5

10:55 pm-10:26 am

1 stop10h 31m

$676

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 3/10

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Tue 3/17

2:28 pm-11:46 pm

1 stop8h 18m

$686

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 6/8

5:50 pm-4:12 pm

2 stops23h 22m

Panama City Tocumen Intl

Sun 7/5

10:55 pm-10:26 am

1 stop10h 31m

$703

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 2/6

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/11

3:20 pm-11:28 pm

1 stop8h 08m

$714

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 2/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 2/10

3:20 pm-11:28 pm

1 stop8h 08m

$773

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/30

6:55 pm-4:04 am

1 stop10h 09m

Panama City Tocumen Intl

Fri 4/3

10:55 pm-10:02 am

1 stop10h 07m

$776

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 2/6

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/11

3:20 pm-11:28 pm

1 stop8h 08m

$833

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 67% on your flight if you consider stops on a Buffalo to Panama flight.

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Fastest flight time	11h 08m
Direct flights	None

The fastest flight from Buffalo to Panama takes 11h 08m

There are no direct flights from Buffalo to Panama. There are no popular flight routes from Buffalo to Panama.

Search flight deals

When did momondo last update prices for flights from Buffalo Airport to Panama?
Prices for flights from Buffalo Airport to Panama were last updated today.
How many operators does momondo search for flights from Buffalo Airport to Panama?
As of January 2026, there is 1 operator available to choose from for flights from Buffalo Airport to Panama.
How old do you have to be to fly from Buffalo Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $497	Free Cancellation	Rating 7.9 8,111 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Buffalo.

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

Flights from Buffalo to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Buffalo.

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Panama

Popular cities in Panama

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Cheap flights from Buffalo to Panama from $348

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama departing on 6/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Buffalo to Panama

Cheap round-trip flights

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United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

See travel insights to Panama from

How to get the cheapest flight ticket from Buffalo to Panama

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 67% on your flight if you consider stops on a Buffalo to Panama flight.

What is the cheapest airline that flies from Buffalo to Panama?

American Airlines and Delta are the most popular carriers operating from Buffalo to Panama

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Fastest flight time

Direct flights

When did momondo last update prices for flights from Buffalo Airport to Panama?

How many operators does momondo search for flights from Buffalo Airport to Panama?

How old do you have to be to fly from Buffalo Airport to Panama?

What documentation or ID do you need to fly to Panama?

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Buffalo to Panama?

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo