What is the cheapest airline that flies from Buffalo to Panama?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Buffalo to Panama

When did momondo last update prices for flights from Buffalo Airport to Panama?

Prices for flights from Buffalo Airport to Panama were last updated today.

How many operators does momondo search for flights from Buffalo Airport to Panama?

As of August 2026, there is 1 operator available to choose from for flights from Buffalo Airport to Panama.

How old do you have to be to fly from Buffalo Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$344 Cheap Flights from Buffalo to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:45 pm - 2:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 10m3 stops New York John F Kennedy Intl Guatemala City La Aurora San José Juan Santamaria Intl

11:25 am - 9:05 amPTY Panama City Tocumen Intl-BUF Buffalo

21h 40m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

$564Multiple Airlines

Wed, Jan 20 - Wed, Feb 3

12:19 pm - 10:30 amBUF Buffalo-PTY Panama City Tocumen Intl

23h 11m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

3:50 pm - 8:24 amPTY Panama City Tocumen Intl-BUF Buffalo

15h 34m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$577Multiple Airlines

Sun, Oct 4 - Sun, Oct 11

12:19 pm - 10:30 amBUF Buffalo-PTY Panama City Tocumen Intl

23h 11m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

11:25 am - 8:24 amPTY Panama City Tocumen Intl-BUF Buffalo

19h 59m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

$583Multiple Airlines

Sun, Oct 4 - Sun, Oct 11

12:19 pm - 2:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

27h 36m3 stops New York John F Kennedy Intl Guatemala City La Aurora San José Juan Santamaria Intl

11:25 am - 8:24 amPTY Panama City Tocumen Intl-BUF Buffalo

19h 59m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

$590Multiple Airlines

Sun, Oct 4 - Sun, Oct 11

6:00 am - 1:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 55m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 11:55 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 35m1 stop Atlanta Hartsfield-Jackson

$713Delta

Wed, Jan 20 - Wed, Feb 3

6:30 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

14h 01m1 stop Newark

9:45 am - 11:11 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 26m1 stop Newark

$713United Airlines

Mon, Oct 12 - Thu, Oct 22

11:40 am - 8:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

8h 22m1 stop Newark

10:00 am - 10:37 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 37m1 stop Newark

$713United Airlines

Tue, Feb 16 - Tue, Feb 23

6:00 am - 8:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

14h 02m1 stop Newark

10:00 am - 10:37 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 37m1 stop Newark

$713United Airlines

Mon, Feb 15 - Tue, Feb 23

11:40 am - 8:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

8h 22m1 stop Newark

10:00 am - 10:37 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 37m1 stop Newark

$713United Airlines

Wed, Feb 17 - Tue, Feb 23

6:00 am - 1:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 55m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 11:55 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 35m1 stop Atlanta Hartsfield-Jackson

$743Delta

Sun, Jan 17 - Thu, Jan 28

Cheap last minute flights

Enter your travel dates to find the best prices.

10:53 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

9h 38m1 stop Newark

3:30 pm - 11:12 pmPTY Panama City Tocumen Intl-BUF Buffalo

30h 42m2 stops Houston George Bush Intcntl Newark

$880United Airlines

Wed, Aug 26 - Sun, Aug 30

5:58 pm - 2:14 pmBUF Buffalo-PTY Panama City Tocumen Intl

21h 16m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

3:30 pm - 4:56 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 26m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$880United Airlines

Wed, Aug 26 - Sun, Aug 30

5:58 pm - 2:14 pmBUF Buffalo-PTY Panama City Tocumen Intl

21h 16m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

3:30 pm - 4:56 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 26m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$883United Airlines

Wed, Aug 26 - Sun, Aug 30

7:59 pm - 6:37 pmBUF Buffalo-PTY Panama City Tocumen Intl

23h 38m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

3:30 pm - 9:28 amPTY Panama City Tocumen Intl-BUF Buffalo

16h 58m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$883United Airlines

Wed, Aug 26 - Sun, Aug 30

6:00 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

14h 31m1 stop Newark

3:30 pm - 4:56 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 26m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$883United Airlines

Wed, Aug 26 - Sun, Aug 30

10:53 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

9h 38m1 stop Newark

3:30 pm - 9:28 amPTY Panama City Tocumen Intl-BUF Buffalo

16h 58m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$883United Airlines

Wed, Aug 26 - Sun, Aug 30

6:05 am - 12:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 50m1 stop Atlanta Hartsfield-Jackson

2:20 pm - 11:59 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 39m1 stop Atlanta Hartsfield-Jackson

$1,067Delta

Wed, Aug 26 - Sun, Aug 30

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United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

United Airlines

Oct 12

BUF6:30 amBuffalo

14h 01m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Oct 22

PTY9:45 amPanama City Tocumen Intl

12h 26m

1 stop

BUF11:11 pmBuffalo

$713

United Airlines

Jan 20

BUF6:45 pmBuffalo

24h 53m

2 stops

PTY7:38 pmPanama City Tocumen Intl

Feb 3

PTY8:55 amPanama City Tocumen Intl

13h 42m

2 stops

BUF10:37 pmBuffalo

$717

United Airlines

Feb 15

BUF6:00 amBuffalo

14h 02m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Feb 23

PTY10:00 amPanama City Tocumen Intl

12h 37m

1 stop

BUF10:37 pmBuffalo

$720

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

Delta

Feb 19

BUF6:59 pmBuffalo

17h 16m

1 stop

PTY12:15 pmPanama City Tocumen Intl

Feb 25

PTY3:20 pmPanama City Tocumen Intl

19h 55m

1 stop

BUF11:15 amBuffalo

$754

Delta

Feb 14

BUF9:00 amBuffalo

28h 55m

2 stops

PTY1:55 pmPanama City Tocumen Intl

Feb 25

PTY3:20 pmPanama City Tocumen Intl

19h 55m

1 stop

BUF11:15 amBuffalo

$814

Delta

Sep 11

BUF6:05 amBuffalo

7h 53m

1 stop

PTY12:58 pmPanama City Tocumen Intl

Sep 18

PTY2:23 pmPanama City Tocumen Intl

8h 29m

1 stop

BUF11:52 pmBuffalo

$833

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Wed 1/20

7:45 pm-2:55 pm

3 stops19h 10m

Panama City Tocumen Intl

Wed 2/3

11:25 am-9:05 am

3 stops21h 40m

$564

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Sun 10/4

12:19 pm-10:30 am

2 stops23h 11m

Panama City Tocumen Intl

Sun 10/11

3:50 pm-8:24 am

2 stops15h 34m

$577

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Sun 10/4

12:19 pm-10:30 am

2 stops23h 11m

Panama City Tocumen Intl

Sun 10/11

11:25 am-8:24 am

3 stops19h 59m

$583

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Sun 10/4

12:19 pm-2:55 pm

3 stops27h 36m

Panama City Tocumen Intl

Sun 10/11

11:25 am-8:24 am

3 stops19h 59m

$590

Quickest round-trip

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Wed 1/20

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/3

3:20 pm-11:55 pm

1 stop8h 35m

$713

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Mon 10/12

6:30 am-7:31 pm

1 stop14h 01m

Panama City Tocumen Intl

Thu 10/22

9:45 am-11:11 pm

1 stop12h 26m

$713

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Tue 2/16

11:40 am-8:02 pm

1 stop8h 22m

Panama City Tocumen Intl

Tue 2/23

10:00 am-10:37 pm

1 stop12h 37m

$713

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Mon 2/15

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Tue 2/23

10:00 am-10:37 pm

1 stop12h 37m

$713

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Wed 2/17

11:40 am-8:02 pm

1 stop8h 22m

Panama City Tocumen Intl

Tue 2/23

10:00 am-10:37 pm

1 stop12h 37m

$713

BuffaloPanama City

BUF Buffalo - PTY Panama City Tocumen Intl

BUFPTY

Buffalo

Sun 1/17

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 1/28

3:20 pm-11:55 pm

1 stop8h 35m

$743

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Buffalo, with most prices found around $0. If you don’t want to visit Panama in August, then you should wait until March to fly from Buffalo, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Buffalo to Panama flights?

You could potentially save up to 45% on your flight if you consider stops on a Buffalo to Panama flight.

Cheap Buffalo to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama

Best Price Found	$344
Fastest flight time	14h 01m
Direct flights	None

The best one-way flight to Panama from Buffalo in the past 72 hours is $344. The best round-trip flight deal from Buffalo to Panama found on momondo in the last 72 hours is $564.

The fastest flight from Buffalo to Panama takes 14h 01m

There are no direct flights from Buffalo to Panama. There are no popular flight routes from Buffalo to Panama.

Search flight deals

Frequently asked questions about flying from Buffalo to Panama

When did momondo last update prices for flights from Buffalo Airport to Panama?
Prices for flights from Buffalo Airport to Panama were last updated today.
How many operators does momondo search for flights from Buffalo Airport to Panama?
As of August 2026, there is 1 operator available to choose from for flights from Buffalo Airport to Panama.
How old do you have to be to fly from Buffalo Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $517	Free Cancellation	Rating 7.8 8,517 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Buffalo.

Can I find flights from Buffalo to Panama with flexible booking policies on momondo?

Flights from Buffalo to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Buffalo.

I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Panama

Flights to Panama Cityfrom $483

Flights to Bocas del Torofrom $1,130

Flights to Davidfrom $440

Flights to Changuinola

Cheap flights from Buffalo to Panama from $344

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama departing on 10/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Buffalo to Panama

Our best United Airlines deals on Buffalo to Panama flight tickets

Delta flights from Buffalo to Panama

Our best Delta deals on Buffalo to Panama flight tickets

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Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

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How to get the cheapest flight ticket from Buffalo to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Buffalo to Panama flights?

What is the cheapest airline that flies from Buffalo to Panama?

Cheap Buffalo to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Buffalo to Panama

Best airlines flying from Buffalo to Panama

Compare and see reviews for airlines that fly from Buffalo to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Buffalo flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year