Cheap flights from Buffalo to Panama from $286
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sun 2/21
5:50 pm-8:02 pm
2 stops26h 12m
Panama City Tocumen Intl
Wed 3/3
4:41 pm-8:31 pm
2 stops27h 50m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sun 2/21
5:30 pm-8:02 pm
1 stop26h 32m
Panama City Tocumen Intl
Wed 3/3
4:41 pm-8:31 pm
2 stops27h 50m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sun 2/21
5:30 pm-8:02 pm
1 stop26h 32m
Panama City Tocumen Intl
Wed 3/3
10:00 am-3:16 pm
1 stop29h 16m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Thu 1/21
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Tue 1/26
3:20 pm-11:55 pm
1 stop8h 35m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Thu 1/21
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Wed 1/27
3:20 pm-11:55 pm
1 stop8h 35m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/20
11:13 am-8:02 pm
1 stop8h 49m
Panama City Tocumen Intl
Wed 2/3
10:00 am-10:59 pm
1 stop12h 59m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 1/19
11:13 am-8:02 pm
1 stop8h 49m
Panama City Tocumen Intl
Tue 1/26
10:00 am-7:32 pm
1 stop9h 32m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/20
7:03 am-8:02 pm
1 stop12h 59m
Panama City Tocumen Intl
Wed 2/3
10:00 am-7:32 pm
1 stop9h 32m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Fri 12/4
6:41 pm-2:03 pm
1 stop19h 22m
Panama City Tocumen Intl
Thu 12/10
3:29 pm-11:05 am
1 stop19h 36m
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Fri 12/4
6:41 pm-2:03 pm
1 stop19h 22m
Panama City Tocumen Intl
Thu 12/10
3:29 pm-8:34 am
2 stops17h 05m
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How to get the cheapest flight ticket from Buffalo to Panama
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Cheap Buffalo to Panama flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama
Frequently asked questions about flying from Buffalo to Panama
When did momondo last update prices for flights from Buffalo Airport to Panama?
Prices for flights from Buffalo Airport to Panama were last updated today.
How many operators does momondo search for flights from Buffalo Airport to Panama?
As of October 2026, there is 1 operator available to choose from for flights from Buffalo Airport to Panama.
How old do you have to be to fly from Buffalo Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
Best airlines flying from Buffalo to Panama
Compare and see reviews for airlines that fly from Buffalo to Panama with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $628 | Free Cancellation | Rating 7.8 8,653 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from Buffalo to Panama?
To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Buffalo.
Can I find flights from Buffalo to Panama with flexible booking policies on momondo?
Flights from Buffalo to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from Buffalo to Panama?
Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Buffalo.
I’m not ready to book a flight from Buffalo to Panama right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to Panama from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.