Cheap flights from Brussels to Chicago from $378

The month of September is, on average, the cheapest month to fly to Chicago from Brussels, with most prices found around $555. If you’re not able to fly to Chicago in September, then February is your next best option. Flight prices from Brussels to Chicago during February average around $561.

The cheapest day to depart on your flight to Chicago is on a Thursday when prices can be found for as low as $740. This is often the case because there is less demand to fly during this day of the week. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Brussels to Chicago for around $853.

Fly from Brussels Bruxelles-National to Chicago O'Hare Intl for the best Brussels - Chicago flight prices

You are more likely to see cheaper flights to Chicago from Brussels when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $699 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Brussels for as low as $586 on momondo.

Historically, on average around 14% of flights between Brussels and Chicago have experienced a delay on any given week. The average delay length over the past 12 months has been 172 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, Emirates have had the least number of delays on this route over the last 12 months; with about 10% of their flights experiencing any sort of delay.

The number of flights available between Brussels and Chicago is 6 per day as of March 2026. The most frequent departure time is 10:00AM, with 100% of daily flights leaving at noon.

As of March 2026, there are 42 flights per week flying from Brussels to Chicago. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.