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Cheap flights from Amarillo to Knoxville from $175

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Amarillo to Knoxville departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Amarillo to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:51 pm - 9:45 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
5h 54m1 stop Houston George Bush Intcntl
United Airlines Logo
7:15 am - 12:11 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
5h 56m1 stop Houston George Bush Intcntl
$331United Airlines
Sat, Sep 5 - Sat, Sep 12
United Airlines Logo
2:51 pm - 9:45 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
5h 54m1 stop Houston George Bush Intcntl
United Airlines Logo
7:15 am - 4:55 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
10h 40m2 stops Houston George Bush Intcntl Denver Intl
$336United Airlines
Sat, Sep 5 - Sat, Sep 12
Southwest Logo
6:10 am - 7:25 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
12h 15m2 stops Dallas Love Field Baltimore/Washington
Southwest Logo
7:50 am - 3:15 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
8h 25m2 stops Baltimore/Washington Dallas Love Field
$347Southwest
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
10:16 am - 5:29 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
6h 13m1 stop Dallas/Fort Worth
American Airlines Logo
5:24 am - 11:53 amTYS  Knoxville McGhee Tyson-AMA Amarillo
7h 29m1 stop Dallas/Fort Worth
$349American Airlines
Mon, Dec 7 - Thu, Dec 10
American Airlines Logo
8:00 am - 3:46 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
6h 46m1 stop Dallas/Fort Worth
American Airlines Logo
12:19 pm - 4:14 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
4h 55m1 stop Dallas/Fort Worth
$349American Airlines
Mon, Jan 25 - Thu, Jan 28
Southwest Logo
6:00 am - 2:05 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
7h 05m1 stop Dallas Love Field
Southwest Logo
1:00 pm - 9:45 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
9h 45m2 stops Orlando Dallas Love Field
$354Southwest
Mon, Dec 7 - Thu, Dec 10
American Airlines Logo
5:00 am - 1:54 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
7h 54m2 stops Dallas/Fort Worth Charlotte Douglas
American Airlines Logo
6:08 am - 12:10 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
7h 02m1 stop Dallas/Fort Worth
$354American Airlines
Mon, Jan 25 - Thu, Jan 28
American Airlines Logo
5:00 am - 1:54 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
7h 54m2 stops Dallas/Fort Worth Charlotte Douglas
American Airlines Logo
12:14 pm - 8:57 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
9h 43m2 stops Charlotte Douglas Dallas/Fort Worth
$359American Airlines
Mon, Jan 25 - Thu, Jan 28
Southwest Logo
6:00 am - 4:40 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
9h 40m2 stops Dallas Love Field Orlando
Southwest Logo
7:55 am - 4:25 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
9h 30m2 stops Baltimore/Washington Dallas Love Field
$359Southwest
Mon, Dec 7 - Thu, Dec 10
American Airlines Logo
10:38 am - 5:38 pmAMA  Amarillo-TYS Knoxville McGhee Tyson
6h 00m1 stop Dallas/Fort Worth
American Airlines Logo
4:44 pm - 10:53 pmTYS  Knoxville McGhee Tyson-AMA Amarillo
7h 09m1 stop Dallas/Fort Worth
$369American Airlines
Tue, Jan 19 - Fri, Jan 22

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American Airlines flights from Amarillo to Knoxville

Our best American Airlines deals on Amarillo to Knoxville flight tickets
American Airlines
Dec 7
AMA10:16 amAmarillo
6h 13m
1 stop
TYS5:29 pmKnoxville McGhee Tyson
Dec 10
TYS5:24 amKnoxville McGhee Tyson
7h 29m
1 stop
AMA11:53 amAmarillo
$349
American Airlines
Jan 19
AMA10:38 amAmarillo
6h 00m
1 stop
TYS5:38 pmKnoxville McGhee Tyson
Jan 22
TYS4:44 pmKnoxville McGhee Tyson
7h 09m
1 stop
AMA10:53 pmAmarillo
$369
American Airlines
Sep 11
AMA6:00 amAmarillo
6h 53m
1 stop
TYS1:53 pmKnoxville McGhee Tyson
Sep 13
TYS6:00 amKnoxville McGhee Tyson
4h 50m
1 stop
AMA9:50 amAmarillo
$370

United Airlines flights from Amarillo to Knoxville

Our best United Airlines deals on Amarillo to Knoxville flight tickets
United Airlines
Sep 5
AMA2:51 pmAmarillo
5h 54m
1 stop
TYS9:45 pmKnoxville McGhee Tyson
Sep 12
TYS7:15 amKnoxville McGhee Tyson
5h 56m
1 stop
AMA12:11 pmAmarillo
$331
United Airlines
Sep 5
AMA2:51 pmAmarillo
5h 54m
1 stop
TYS9:45 pmKnoxville McGhee Tyson
Sep 12
TYS7:15 amKnoxville McGhee Tyson
10h 40m
2 stops
AMA4:55 pmAmarillo
$336
United Airlines
Dec 5
AMA3:00 pmAmarillo
7h 19m
1 stop
TYS11:19 pmKnoxville McGhee Tyson
Dec 9
TYS9:15 amKnoxville McGhee Tyson
6h 03m
1 stop
AMA2:18 pmAmarillo
$379

momondo Fare Finder

 
Customize your flight search to find flights from Amarillo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Amarillo to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Sat 9/5

2:51 pm-9:45 pm

1 stop5h 54m

Knoxville McGhee Tyson

Sat 9/12

7:15 am-12:11 pm

1 stop5h 56m

$331

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Sat 9/5

2:51 pm-9:45 pm

1 stop5h 54m

Knoxville McGhee Tyson

Sat 9/12

7:15 am-4:55 pm

2 stops10h 40m

$336

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Sat 9/5

6:10 am-7:25 pm

2 stops12h 15m

Knoxville McGhee Tyson

Sat 9/12

7:50 am-3:15 pm

2 stops8h 25m

$347

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 12/7

10:16 am-5:29 pm

1 stop6h 13m

Knoxville McGhee Tyson

Thu 12/10

5:24 am-11:53 am

1 stop7h 29m

$349
Quickest round-trip

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 1/25

8:00 am-3:46 pm

1 stop6h 46m

Knoxville McGhee Tyson

Thu 1/28

12:19 pm-4:14 pm

1 stop4h 55m

$349

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 12/7

6:00 am-2:05 pm

1 stop7h 05m

Knoxville McGhee Tyson

Thu 12/10

1:00 pm-9:45 pm

2 stops9h 45m

$354

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 1/25

5:00 am-1:54 pm

2 stops7h 54m

Knoxville McGhee Tyson

Thu 1/28

6:08 am-12:10 pm

1 stop7h 02m

$354

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 1/25

5:00 am-1:54 pm

2 stops7h 54m

Knoxville McGhee Tyson

Thu 1/28

12:14 pm-8:57 pm

2 stops9h 43m

$359

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Mon 12/7

6:00 am-4:40 pm

2 stops9h 40m

Knoxville McGhee Tyson

Thu 12/10

7:55 am-4:25 pm

2 stops9h 30m

$359

AmarilloKnoxville

AMA Amarillo - TYS Knoxville McGhee Tyson

AMATYS

Amarillo

Tue 1/19

10:38 am-5:38 pm

1 stop6h 00m

Knoxville McGhee Tyson

Fri 1/22

4:44 pm-10:53 pm

1 stop7h 09m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Amarillo to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Amarillo to Knoxville McGhee Tyson?

American Airlines, Southwest, and United Airlines are the most popular carriers operating from Amarillo to Knoxville McGhee Tyson

When to book flights from Amarillo to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Amarillo to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Amarillo to Knoxville (AMA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Amarillo to Knoxville

Fastest flight time

6h 25m

Direct flights

None
The fastest flight from Amarillo to Knoxville takes 6h 25m
There are no direct flights from Amarillo to Knoxville. There are no popular flight routes from Amarillo to Knoxville.
Search flight deals

Frequently asked questions about flying from Amarillo to Knoxville

  • How far is Amarillo to Knoxville McGhee Tyson by plane?

    The distance between Amarillo and Knoxville McGhee Tyson is about 1005.4 mi. 6h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Amarillo Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Amarillo Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Amarillo Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Amarillo Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Amarillo Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Amarillo to Knoxville?

Best airlines flying from Amarillo to Knoxville

Compare and see reviews for airlines that fly from Amarillo to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $305Free CancellationRating
7.1
11,903 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Amarillo to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Amarillo.

Can I find flights from Amarillo to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Amarillo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Amarillo to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Amarillo.

I’m not ready to book a flight from Amarillo to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Amarillo to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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