Cheap flights from Florence, South Carolina (FLO) from $319

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Fly to

Route

Depart

Return

Price

Cheapest one-way

FlorenceMiami

FLO - MIA

FLOMIA

Florence

Sat 9/5

9:00 am-3:41 pm

1 stop6h 41m

$231

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Sat 8/15

6:22 am-11:59 pm

2 stops17h 37m

$334

Quickest one-way

FlorenceMiami

FLO - MIA

FLOMIA

Florence

Sun 1/3

12:51 pm-4:51 pm

1 stop4h 00m

$339

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Sun 10/25

2:34 pm-8:59 pm

1 stop6h 25m

$347

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Sun 9/20

5:09 am-11:29 am

1 stop6h 20m

$353

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Sun 9/20

2:36 pm-8:59 pm

1 stop6h 23m

$363

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Sun 9/20

5:09 am-11:05 am

1 stop5h 56m

$363

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Sun 10/25

2:34 pm-8:04 pm

1 stop5h 30m

$373

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Sat 11/14

3:37 pm-10:29 pm

1 stop6h 52m

$387

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Sat 11/14

3:37 pm-8:29 pm

1 stop4h 52m

$387

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Florence, South Carolina?

Currently, destinations can be reached directly via flights from Florence, South Carolina.

Find the cheapest flights from Florence, South Carolina

One-way

Last minute

International

Domestic

Cheap one-way flights from Florence, South Carolina

Enter your travel dates to find the best prices.

9:00 am - 3:41 pm

FLO

MIA

6h 41m

1 stop

$231American Airlines

Sat, Sep 5

6:22 am - 11:59 pm

FLO

EWR

17h 37m

2 stops

$334American Airlines

Sat, Aug 15

12:51 pm - 4:51 pm

FLO

MIA

4h 00m

1 stop

$339American Airlines

Sun, Jan 3

2:34 pm - 8:59 pm

FLO

EWR

6h 25m

1 stop

$347American Airlines

Sun, Oct 25

5:09 am - 11:29 am

FLO

JFK

6h 20m

1 stop

$353American Airlines

Sun, Sep 20

2:36 pm - 8:59 pm

FLO

EWR

6h 23m

1 stop

$363American Airlines

Sun, Sep 20

5:09 am - 11:05 am

FLO

LGA

5h 56m

1 stop

$363American Airlines

Sun, Sep 20

2:34 pm - 8:04 pm

FLO

JFK

5h 30m

1 stop

$373American Airlines

Sun, Oct 25

3:37 pm - 10:29 pm

FLO

JFK

6h 52m

1 stop

$387American Airlines

Sat, Nov 14

3:37 pm - 8:29 pm

FLO

EWR

4h 52m

1 stop

$387American Airlines

Sat, Nov 14

Flights from Florence, South Carolina - Travel Insights & Trends

Get data-powered insights and trends into flights from Florence, South Carolina to help you craft the best travel plan.

Prices

Other information

Frequently asked questions regarding flights from Florence, South Carolina

Which airlines are currently offering the cheapest flights from Florence, South Carolina?

Our data suggests that currently, the cheapest flights from Florence, South Carolina are being offered by American Airlines. For example, American Airlines flights from Florence, South Carolina to Houston George Bush Intcntl Airport start at $308.

What is the cheapest flight available from Florence, South Carolina?

Currently, the cheapest flight from Florence, South Carolina found by our users is for $247 to Charlotte. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $491 to travel from Florence, South Carolina to Charlotte.

Which destinations have the most frequent flights from Florence, South Carolina?

Charlotte is currently the destination served most frequently from Florence, South Carolina, with 2 flights per day on average.

Which airlines can you fly with from Florence, South Carolina?

Airlines including American Airlines frequently fly from Florence, South Carolina. You can view other airlines by performing a quick search in the form above.

When did momondo last update prices for flights from Florence Airport?

Prices for flights from Florence Airport were last updated today.

How many operators does momondo search for flights from Florence Airport?

The number of operators available for flights from Florence Airport is 1 as of July 2026.

How old do you have to be to fly from Florence Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.