Cheap flights from Florence, South Carolina (FLO) from $289

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Fly to

Route

Depart

Return

Price

Cheapest one-way

Quickest one-way

FlorenceNashville

FLO - BNA

FLOBNA

Florence

Thu 6/18

2:35 pm-6:28 pm

1 stop4h 53m

$175

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Tue 5/26

5:05 am-11:30 pm

2 stops18h 25m

$304

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 6/10

5:05 am-4:29 pm

2 stops11h 24m

$309

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sat 7/18

2:35 pm-12:15 am

2 stops10h 40m

$334

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Tue 8/25

3:22 pm-4:38 pm

2 stops25h 16m

$337

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Fri 5/15

5:20 am-4:30 pm

2 stops11h 10m

$358

FlorenceNashville

FLO - BNA

FLOBNA

Florence

Thu 6/18

2:35 pm-9:31 pm

2 stops7h 56m

$364

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Tue 5/12

4:02 pm-10:00 pm

1 stop5h 58m

$387

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Tue 5/12

4:02 pm-10:42 pm

1 stop6h 40m

$387

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Tue 5/12

6:15 am-12:59 pm

1 stop6h 44m

$387

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Florence, South Carolina?

Currently, destinations can be reached directly via flights from Florence, South Carolina.

Find the cheapest flights from Florence, South Carolina

One-way

Last minute

International

Domestic

Cheap one-way flights from Florence, South Carolina

Enter your travel dates to find the best prices.

2:35 pm - 6:28 pm

FLO

BNA

4h 53m

1 stop

$175American Airlines

Thu, Jun 18

5:05 am - 11:30 pm

FLO

EWR

18h 25m

2 stops

$304American Airlines

Tue, May 26

5:05 am - 4:29 pm

FLO

JFK

11h 24m

2 stops

$309American Airlines

Wed, Jun 10

2:35 pm - 12:15 am

FLO

STL

10h 40m

2 stops

$334American Airlines

Sat, Jul 18

3:22 pm - 4:38 pm

FLO

EWR

25h 16m

2 stops

$337American Airlines

Tue, Aug 25

5:20 am - 4:30 pm

FLO

EWR

11h 10m

2 stops

$358American Airlines

Fri, May 15

2:35 pm - 9:31 pm

FLO

BNA

7h 56m

2 stops

$364American Airlines

Thu, Jun 18

4:02 pm - 10:00 pm

FLO

JFK

5h 58m

1 stop

$387American Airlines

Tue, May 12

4:02 pm - 10:42 pm

FLO

EWR

6h 40m

1 stop

$387American Airlines

Tue, May 12

6:15 am - 12:59 pm

FLO

LGA

6h 44m

1 stop

$387American Airlines

Tue, May 12

Flights from Florence, South Carolina - Travel Insights & Trends

Get data-powered insights and trends into flights from Florence, South Carolina to help you craft the best travel plan.

Prices

Other information

Frequently asked questions regarding flights from Florence, South Carolina

Which airlines are currently offering the cheapest flights from Florence, South Carolina?

Our data suggests that currently, the cheapest flights from Florence, South Carolina are being offered by American Airlines. For example, American Airlines flights from Florence, South Carolina to Chicago O'Hare Intl Airport start at $176.

What is the cheapest flight available from Florence, South Carolina?

Currently, the cheapest flight from Florence, South Carolina found by our users is for $172 to Charlotte. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $458 to travel from Florence, South Carolina to Charlotte.

Which destinations have the most frequent flights from Florence, South Carolina?

Charlotte is currently the destination served most frequently from Florence, South Carolina, with 2 flights per day on average.

Which airlines can you fly with from Florence, South Carolina?

Airlines including American Airlines frequently fly from Florence, South Carolina. You can view other airlines by performing a quick search in the form above.

When did momondo last update prices for flights from Florence Airport?

Prices for flights from Florence Airport were last updated today.

How many operators does momondo search for flights from Florence Airport?

The number of operators available for flights from Florence Airport is 1 as of May 2026.

How old do you have to be to fly from Florence Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.