Cheap flights from Florence, South Carolina (FLO) from $289

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Fly to

Route

Depart

Return

Price

Cheapest one-way

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 4/1

5:16 am-11:00 am

1 stop5h 44m

$200

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 4/1

5:16 am-1:33 pm

2 stops8h 17m

$205

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Wed 4/1

5:16 am-11:59 am

1 stop6h 43m

$214

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Wed 4/1

5:16 am-1:46 pm

2 stops8h 30m

$219

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Sat 5/16

5:20 am-12:03 pm

1 stop6h 43m

$261

Quickest one-way

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Thu 4/2

5:16 am-9:21 am

1 stop4h 05m

$332

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Thu 4/2

5:16 am-1:50 pm

2 stops8h 34m

$337

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Fri 5/1

5:20 am-1:17 pm

2 stops7h 57m

$339

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Sat 5/16

5:20 am-3:08 pm

2 stops9h 48m

$340

FlorenceDenver

FLO - DEN

FLODEN

Florence

Tue 4/28

6:15 am-5:02 pm

2 stops12h 47m

$386

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Florence, South Carolina?

Currently, destinations can be reached directly via flights from Florence, South Carolina.

Find the cheapest flights from Florence, South Carolina

One-way

Last minute

International

Domestic

Cheap one-way flights from Florence, South Carolina

Enter your travel dates to find the best prices.

5:16 am - 11:00 am

FLO

JFK

5h 44m

1 stop

$200American Airlines

Wed, Apr 1

5:16 am - 1:33 pm

FLO

JFK

8h 17m

2 stops

$205American Airlines

Wed, Apr 1

5:16 am - 11:59 am

FLO

LGA

6h 43m

1 stop

$214American Airlines

Wed, Apr 1

5:16 am - 1:46 pm

FLO

LGA

8h 30m

2 stops

$219American Airlines

Wed, Apr 1

5:20 am - 12:03 pm

FLO

MCO

6h 43m

1 stop

$261American Airlines

Sat, May 16

5:16 am - 9:21 am

FLO

LGA

4h 05m

1 stop

$332American Airlines

Thu, Apr 2

5:16 am - 1:50 pm

FLO

LGA

8h 34m

2 stops

$337American Airlines

Thu, Apr 2

5:20 am - 1:17 pm

FLO

LGA

7h 57m

2 stops

$339American Airlines

Fri, May 1

5:20 am - 3:08 pm

FLO

MCO

9h 48m

2 stops

$340American Airlines

Sat, May 16

6:15 am - 5:02 pm

FLO

DEN

12h 47m

2 stops

$386American Airlines

Tue, Apr 28

Flights from Florence, South Carolina - Travel Insights & Trends

Get data-powered insights and trends into flights from Florence, South Carolina to help you craft the best travel plan.

Prices

Other information

Frequently asked questions regarding flights from Florence, South Carolina

Which airlines are currently offering the cheapest flights from Florence, South Carolina?

Our data suggests that currently, the cheapest flights from Florence, South Carolina are being offered by American Airlines. For example, American Airlines flights from Florence, South Carolina to Chicago O'Hare Intl Airport start at $176.

What is the cheapest flight available from Florence, South Carolina?

Currently, the cheapest flight from Florence, South Carolina found by our users is for $232 to Charlotte. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $562 to travel from Florence, South Carolina to Charlotte.

Which destinations have the most frequent flights from Florence, South Carolina?

Charlotte is currently the destination served most frequently from Florence, South Carolina, with 2 flights per day on average.

Which airlines can you fly with from Florence, South Carolina?

Airlines including American Airlines frequently fly from Florence, South Carolina. You can view other airlines by performing a quick search in the form above.

When did momondo last update prices for flights from Florence Airport?

Prices for flights from Florence Airport were last updated today.

How many operators does momondo search for flights from Florence Airport?

The number of operators available for flights from Florence Airport is 1 as of March 2026.

How old do you have to be to fly from Florence Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.