Cheap flights from Florence, South Carolina (FLO) from $246

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Route

Depart

Return

Price

Cheapest one-way

FlorenceNew York

FLO Florence - LGA New York LaGuardia

FLOLGA

Florence

Wed 10/7

2:34 pm-7:59 pm

1 stop5h 25m

$246

FlorenceNew York

FLO Florence - JFK New York John F Kennedy Intl

FLOJFK

Florence

Wed 10/7

2:34 pm-8:04 pm

1 stop5h 30m

$246

FlorenceNewark

FLO Florence - EWR Newark

FLOEWR

Florence

Wed 10/7

2:34 pm-6:39 pm

1 stop4h 05m

$246

Quickest one-way

FlorenceNew York

FLO Florence - LGA New York LaGuardia

FLOLGA

Florence

Tue 9/22

1:43 pm-5:31 pm

1 stop3h 48m

$392

FlorenceNew York

FLO Florence - JFK New York John F Kennedy Intl

FLOJFK

Florence

Tue 9/22

6:24 am-10:29 am

1 stop4h 05m

$392

FlorenceNew York

FLO Florence - JFK New York John F Kennedy Intl

FLOJFK

Florence

Tue 9/15

1:43 pm-8:00 pm

1 stop6h 17m

$392

FlorenceNewark

FLO Florence - EWR Newark

FLOEWR

Florence

Tue 9/22

1:43 pm-8:47 pm

1 stop7h 04m

$392

FlorenceOrlando

FLO Florence - MCO Orlando

FLOMCO

Florence

Fri 11/27

2:35 pm-11:07 pm

2 stops8h 32m

$414

FlorenceNew York

FLO Florence - LGA New York LaGuardia

FLOLGA

Florence

Tue 9/22

6:24 am-12:49 pm

2 stops6h 25m

$425

FlorenceNew York

FLO Florence - JFK New York John F Kennedy Intl

FLOJFK

Florence

Tue 9/15

6:24 am-12:59 pm

2 stops6h 35m

$425

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Florence, South Carolina?

Currently, destinations can be reached directly via flights from Florence, South Carolina.

Find the cheapest flights from Florence, South Carolina

One-way

Last minute

International

Domestic

Cheap one-way flights from Florence, South Carolina

Enter your travel dates to find the best prices.

2:34 pm - 7:59 pmFLO Florence-LGA New York LaGuardia

5h 25m1 stop Charlotte Douglas

$246American Airlines

Wed, Oct 7

2:34 pm - 8:04 pmFLO Florence-JFK New York John F Kennedy Intl

5h 30m1 stop Charlotte Douglas

$246American Airlines

Wed, Oct 7

2:34 pm - 6:39 pmFLO Florence-EWR Newark

4h 05m1 stop Charlotte Douglas

$246American Airlines

Wed, Oct 7

1:43 pm - 5:31 pmFLO Florence-LGA New York LaGuardia

3h 48m1 stop Charlotte Douglas

$392American Airlines

Tue, Sep 22

6:24 am - 10:29 amFLO Florence-JFK New York John F Kennedy Intl

4h 05m1 stop Charlotte Douglas

$392American Airlines

Tue, Sep 22

1:43 pm - 8:00 pmFLO Florence-JFK New York John F Kennedy Intl

6h 17m1 stop Charlotte Douglas

$392American Airlines

Tue, Sep 15

1:43 pm - 8:47 pmFLO Florence-EWR Newark

7h 04m1 stop Charlotte Douglas

$392American Airlines

Tue, Sep 22

2:35 pm - 11:07 pmFLO Florence-MCO Orlando

8h 32m2 stops Charlotte Douglas Philadelphia

$414American Airlines

Fri, Nov 27

6:24 am - 12:49 pmFLO Florence-LGA New York LaGuardia

6h 25m2 stops Charlotte Douglas Washington, D.C. Reagan-National

$425American Airlines

Tue, Sep 22

6:24 am - 12:59 pmFLO Florence-JFK New York John F Kennedy Intl

6h 35m2 stops Charlotte Douglas Boston Logan Intl

$425American Airlines

Tue, Sep 15

Last-minute flight deals from Florence, South Carolina

Enter your travel dates to find the best prices.

6:22 am - 10:30 amFLO Florence-JFK New York John F Kennedy Intl

4h 08m1 stop Charlotte Douglas

8:00 am - 2:56 pmJFK New York John F Kennedy Intl-FLO Florence

6h 56m1 stop Charlotte Douglas

$607American Airlines

Sat, Aug 29 - Mon, Aug 31

6:22 am - 11:13 amFLO Florence-MIA Miami

4h 51m1 stop Charlotte Douglas

5:20 pm - 10:59 pmMIA Miami-FLO Florence

5h 39m1 stop Charlotte Douglas

$610American Airlines

Thu, Aug 27 - Sat, Aug 29

3:22 pm - 10:00 pmFLO Florence-EWR Newark

6h 38m1 stop Charlotte Douglas

7:28 pm - 11:58 pmEWR Newark-FLO Florence

4h 30m1 stop Charlotte Douglas

$621American Airlines

Fri, Aug 28 - Sun, Aug 30

6:22 am - 1:19 pmFLO Florence-JFK New York John F Kennedy Intl

6h 57m2 stops Charlotte Douglas Boston Logan Intl

5:00 pm - 10:59 pmJFK New York John F Kennedy Intl-FLO Florence

5h 59m1 stop Charlotte Douglas

$660American Airlines

Sat, Aug 29 - Mon, Aug 31

6:22 am - 5:42 pmFLO Florence-JFK New York John F Kennedy Intl

11h 20m2 stops Charlotte Douglas Washington, D.C. Reagan-National

6:30 am - 2:56 pmJFK New York John F Kennedy Intl-FLO Florence

8h 26m2 stops Washington, D.C. Reagan-National Charlotte Douglas

$771American Airlines

Sat, Aug 29 - Mon, Aug 31

5:05 am - 9:14 pmFLO Florence-EWR Newark

16h 09m2 stops Charlotte Douglas Chicago O'Hare Intl

10:42 am - 10:59 pmEWR Newark-FLO Florence

12h 17m2 stops Chicago O'Hare Intl Charlotte Douglas

$836American Airlines

Sun, Aug 30 - Tue, Sep 8

2:37 pm - 9:59 amFLO Florence-EWR Newark

19h 22m1 stop Charlotte Douglas

1:33 pm - 10:59 pmEWR Newark-FLO Florence

9h 26m1 stop Charlotte Douglas

$841American Airlines

Sun, Aug 30 - Tue, Sep 8

2:37 pm - 6:38 pmFLO Florence-EWR Newark

4h 01m1 stop Charlotte Douglas

10:42 am - 10:59 pmEWR Newark-FLO Florence

12h 17m2 stops Chicago O'Hare Intl Charlotte Douglas

$881American Airlines

Sun, Aug 30 - Tue, Sep 8

3:22 pm - 9:52 pmFLO Florence-MIA Miami

6h 30m1 stop Charlotte Douglas

1:45 pm - 10:59 pmMIA Miami-FLO Florence

9h 14m2 stops Orlando Charlotte Douglas

$947American Airlines

Thu, Aug 27 - Sat, Aug 29

3:22 pm - 10:02 amFLO Florence-EWR Newark

18h 40m2 stops Charlotte Douglas Chicago O'Hare Intl

7:28 pm - 11:58 pmEWR Newark-FLO Florence

4h 30m1 stop Charlotte Douglas

$974American Airlines

Fri, Aug 28 - Sun, Aug 30

Cheapest international flights from Florence, South Carolina

Enter your travel dates to find the best prices.

6:24 am - 1:13 pmFLO Florence-STT Saint Thomas Island Cyril E King

5h 49m1 stop Charlotte Douglas

4:53 pm - 3:09 pmSTT Saint Thomas Island Cyril E King-FLO Florence

23h 16m2 stops Miami Charlotte Douglas

$566American Airlines

Tue, Nov 10 - Tue, Nov 10

6:24 am - 1:13 pmFLO Florence-STT Saint Thomas Island Cyril E King

5h 49m1 stop Charlotte Douglas

4:33 pm - 10:59 pmSTT Saint Thomas Island Cyril E King-FLO Florence

7h 26m1 stop Charlotte Douglas

$603American Airlines

Tue, Nov 10 - Tue, Nov 10

1:43 pm - 6:42 pmFLO Florence-YYZ Toronto Pearson Intl

4h 59m1 stop Charlotte Douglas

5:45 pm - 10:58 pmYYZ Toronto Pearson Intl-FLO Florence

5h 13m1 stop Charlotte Douglas

$726American Airlines

Sat, Sep 12 - Sat, Sep 19

6:18 pm - 12:26 pmFLO Florence-SJO San José Juan Santamaria Intl

19h 08m2 stops Charlotte Douglas Miami

11:25 am - 11:59 pmSJO San José Juan Santamaria Intl-FLO Florence

11h 34m2 stops Miami Charlotte Douglas

$733American Airlines

Sat, Feb 20 - Tue, Mar 2

6:24 am - 3:38 pmFLO Florence-YYZ Toronto Pearson Intl

9h 14m2 stops Charlotte Douglas Philadelphia

5:45 pm - 10:58 pmYYZ Toronto Pearson Intl-FLO Florence

5h 13m1 stop Charlotte Douglas

$736American Airlines

Sat, Sep 12 - Sat, Sep 19

6:24 am - 1:33 pmFLO Florence-YYZ Toronto Pearson Intl

7h 09m2 stops Charlotte Douglas Washington, D.C. Reagan-National

12:40 pm - 10:58 pmYYZ Toronto Pearson Intl-FLO Florence

10h 18m2 stops Philadelphia Charlotte Douglas

$742American Airlines

Sat, Sep 12 - Sat, Sep 19

5:35 pm - 10:42 pmFLO Florence-YYZ Toronto Pearson Intl

5h 07m1 stop Charlotte Douglas

6:20 pm - 10:43 pmYYZ Toronto Pearson Intl-FLO Florence

4h 23m1 stop Charlotte Douglas

$748American Airlines

Fri, Feb 5 - Tue, Feb 9

6:18 pm - 1:46 pmFLO Florence-SJO San José Juan Santamaria Intl

44h 28m2 stops Charlotte Douglas Dallas/Fort Worth

7:45 am - 11:59 pmSJO San José Juan Santamaria Intl-FLO Florence

15h 14m2 stops Miami Charlotte Douglas

$751American Airlines

Fri, Feb 19 - Tue, Mar 2

5:09 am - 10:32 pmFLO Florence-SJU San Juan Luis Munoz Marin Intl

16h 23m2 stops Charlotte Douglas Miami

8:00 am - 11:57 pmSJU San Juan Luis Munoz Marin Intl-FLO Florence

16h 57m2 stops Miami Charlotte Douglas

$755American Airlines

Tue, Dec 22 - Tue, Dec 29

5:35 pm - 10:42 pmFLO Florence-YYZ Toronto Pearson Intl

5h 07m1 stop Charlotte Douglas

12:30 pm - 10:43 pmYYZ Toronto Pearson Intl-FLO Florence

10h 13m2 stops Philadelphia Charlotte Douglas

$758American Airlines

Fri, Feb 5 - Tue, Feb 9

Cheapest domestic flights from Florence, South Carolina

Enter your travel dates to find the best prices.

6:24 am - 10:29 amFLO Florence-JFK New York John F Kennedy Intl

4h 05m1 stop Charlotte Douglas

6:30 am - 1:18 pmJFK New York John F Kennedy Intl-FLO Florence

6h 48m1 stop Charlotte Douglas

$363American Airlines

Wed, Sep 23 - Wed, Sep 30

1:43 pm - 8:47 pmFLO Florence-EWR Newark

7h 04m1 stop Charlotte Douglas

7:37 am - 1:18 pmEWR Newark-FLO Florence

5h 41m1 stop Charlotte Douglas

$363American Airlines

Wed, Sep 23 - Wed, Sep 30

6:24 am - 11:05 amFLO Florence-LGA New York LaGuardia

4h 41m1 stop Charlotte Douglas

4:59 pm - 10:58 pmLGA New York LaGuardia-FLO Florence

5h 59m1 stop Charlotte Douglas

$363American Airlines

Wed, Sep 23 - Wed, Sep 30

6:24 am - 11:29 amFLO Florence-JFK New York John F Kennedy Intl

5h 05m1 stop Charlotte Douglas

5:10 pm - 10:58 pmJFK New York John F Kennedy Intl-FLO Florence

5h 48m1 stop Charlotte Douglas

$364American Airlines

Sat, Sep 26 - Sat, Oct 3

6:24 am - 11:05 amFLO Florence-LGA New York LaGuardia

4h 41m1 stop Charlotte Douglas

4:59 pm - 10:58 pmLGA New York LaGuardia-FLO Florence

5h 59m1 stop Charlotte Douglas

$364American Airlines

Sat, Sep 26 - Sat, Oct 3

2:37 pm - 8:00 pmFLO Florence-JFK New York John F Kennedy Intl

5h 23m1 stop Charlotte Douglas

7:59 am - 1:18 pmJFK New York John F Kennedy Intl-FLO Florence

5h 19m1 stop Charlotte Douglas

$417American Airlines

Sat, Sep 5 - Wed, Sep 9

2:37 pm - 6:38 pmFLO Florence-EWR Newark

4h 01m1 stop Charlotte Douglas

5:29 pm - 10:58 pmEWR Newark-FLO Florence

5h 29m1 stop Charlotte Douglas

$417American Airlines

Sat, Sep 5 - Wed, Sep 9

9:00 am - 3:04 pmFLO Florence-LGA New York LaGuardia

6h 04m1 stop Charlotte Douglas

4:59 pm - 10:58 pmLGA New York LaGuardia-FLO Florence

5h 59m1 stop Charlotte Douglas

$417American Airlines

Sat, Sep 5 - Wed, Sep 9

3:37 pm - 10:29 pmFLO Florence-JFK New York John F Kennedy Intl

6h 52m1 stop Charlotte Douglas

7:59 am - 2:09 pmJFK New York John F Kennedy Intl-FLO Florence

6h 10m1 stop Charlotte Douglas

$420American Airlines

Wed, Nov 18 - Mon, Nov 23

3:37 pm - 8:29 pmFLO Florence-EWR Newark

4h 52m1 stop Charlotte Douglas

9:30 am - 2:09 pmEWR Newark-FLO Florence

4h 39m1 stop Charlotte Douglas

$420American Airlines

Wed, Nov 18 - Mon, Nov 23

Flights from Florence, South Carolina - Travel Insights & Trends

Get data-powered insights and trends into flights from Florence, South Carolina to help you craft the best travel plan.

Prices

Other information

Frequently asked questions regarding flights from Florence, South Carolina

Which airlines are currently offering the cheapest flights from Florence, South Carolina?

Our data suggests that currently, the cheapest flights from Florence, South Carolina are being offered by American Airlines. For example, American Airlines flights from Florence, South Carolina to Houston George Bush Intcntl Airport start at $308.

What is the cheapest flight available from Florence, South Carolina?

Currently, the cheapest flight from Florence, South Carolina found by our users is for $221 to Charlotte. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $501 to travel from Florence, South Carolina to Charlotte.

Which airlines can you fly with from Florence, South Carolina?

Airlines including American Airlines frequently fly from Florence, South Carolina. You can view other airlines by performing a quick search in the form above.

When did momondo last update prices for flights from Florence Airport?

Prices for flights from Florence Airport were last updated today.

How many operators does momondo search for flights from Florence Airport?

The number of operators available for flights from Florence Airport is 1 as of August 2026.

How old do you have to be to fly from Florence Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.