Cheap flights from Cape Girardeau from $73

Our data suggests that currently, the cheapest flights from Cape Girardeau are being offered by Contour. For example, Contour flights from Cape Girardeau to Chicago start at $118.

Currently, the cheapest flight from Cape Girardeau found by our users is for $61 to Chicago O'Hare Intl Airport. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $121 to travel from Cape Girardeau to Chicago O'Hare Intl Airport.

Chicago and Chicago O'Hare Intl Airport are currently the destinations served most frequently from Cape Girardeau, with 2 and 2 flights per day on average, respectively.

Airlines including Contour frequently fly from Cape Girardeau. You can view other airlines by performing a quick search in the form above.

Prices for flights from Cape Girardeau Airport are updated daily.

There is 1 operator available for flights from Cape Girardeau Airport as of September 2025.

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cape Girardeau Airport.

The travel and health documents you'll need for your trip to Cape Girardeau Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cape Girardeau Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.