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Cheap flights from Wilmington to Panama from $440

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Wilmington to Panama departing on 1/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:29 pm - 1:27 pmILM-PTY
19h 58m2 stops
American Airlines Logo
2:27 pm - 9:57 amPTY-ILM
19h 30m2 stops
$440American Airlines
Find Deal
Mon, Jan 26 - Fri, Jan 30
American Airlines Logo
7:13 pm - 1:27 pmILM-PTY
18h 14m1 stop
American Airlines Logo
4:50 pm - 11:57 pmPTY-ILM
7h 07m1 stop
$445American Airlines
Find Deal
Mon, Jan 26 - Fri, Jan 30
American Airlines Logo
6:00 am - 1:43 pmILM-PTY
7h 43m1 stop
American Airlines Logo
4:43 pm - 11:59 pmPTY-ILM
7h 16m1 stop
$476American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
6:00 am - 1:43 pmILM-PTY
7h 43m1 stop
American Airlines Logo
4:43 pm - 1:04 pmPTY-ILM
20h 21m2 stops
$480American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
6:00 am - 3:52 pmILM-PTY
9h 52m1 stop
American Airlines Logo
2:52 pm - 11:57 amPTY-ILM
21h 05m2 stops
$485American Airlines
Find Deal
Sat, Jan 17 - Sun, Feb 15
American Airlines Logo
5:01 am - 3:54 pmILM-PTY
10h 53m1 stop
American Airlines Logo
4:31 pm - 11:57 pmPTY-ILM
7h 26m1 stop
$486American Airlines
Find Deal
Fri, Jan 2 - Wed, Jan 7
American Airlines Logo
5:01 am - 1:53 pmILM-PTY
8h 52m1 stop
American Airlines Logo
4:50 pm - 1:51 pmPTY-ILM
21h 01m2 stops
$490American Airlines
Find Deal
Fri, Jan 2 - Fri, Jan 9
Multiple Airlines Logo
7:01 pm - 6:55 pmILM-PTY
23h 54m3 stops
Multiple Airlines Logo
9:45 am - 10:20 pmPTY-ILM
36h 35m3 stops
$721Multiple Airlines
Find Deal
Fri, Jan 2 - Wed, Jan 7
Delta Logo
6:00 am - 1:56 pmILM-PTY
7h 56m1 stop
Delta Logo
3:37 pm - 1:38 pmPTY-ILM
22h 01m1 stop
$757Delta
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Sat, Nov 8 - Mon, Nov 10
Delta Logo
6:00 am - 1:56 pmILM-PTY
7h 56m1 stop
Delta Logo
3:37 pm - 11:15 pmPTY-ILM
7h 38m1 stop
$984Delta
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Sat, Nov 8 - Sun, Nov 9

American Airlines flights from Wilmington to Panama

Our best American Airlines deals on Wilmington to Panama flight tickets
American Airlines
Jan 26
ILM5:29 pmWilmington New Hanover County
19h 58m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 30
PTY2:27 pmPanama City Tocumen Intl
19h 30m
2 stops
ILM9:57 amWilmington New Hanover County
$440
Find similar
American Airlines
Jan 26
ILM7:13 pmWilmington New Hanover County
18h 14m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Jan 30
PTY4:50 pmPanama City Tocumen Intl
7h 07m
1 stop
ILM11:57 pmWilmington New Hanover County
$445
Find similar
American Airlines
Nov 26
ILM6:00 amWilmington New Hanover County
7h 43m
1 stop
PTY1:43 pmPanama City Tocumen Intl
Dec 3
PTY4:43 pmPanama City Tocumen Intl
7h 16m
1 stop
ILM11:59 pmWilmington New Hanover County
$476
Find similar

Delta flights from Wilmington to Panama

Our best Delta deals on Wilmington to Panama flight tickets
Delta
Nov 3
ILM6:00 amWilmington New Hanover County
7h 56m
1 stop
PTY1:56 pmPanama City Tocumen Intl
Nov 10
PTY3:37 pmPanama City Tocumen Intl
25h 41m
1 stop
ILM5:18 pmWilmington New Hanover County
$553
Find similar
Delta
Nov 3
ILM6:00 amWilmington New Hanover County
7h 56m
1 stop
PTY1:56 pmPanama City Tocumen Intl
Nov 5
PTY3:21 pmPanama City Tocumen Intl
7h 18m
1 stop
ILM10:39 pmWilmington New Hanover County
$576
Find similar
Delta
Nov 3
ILM6:00 amWilmington New Hanover County
7h 56m
1 stop
PTY1:56 pmPanama City Tocumen Intl
Nov 6
PTY3:21 pmPanama City Tocumen Intl
25h 49m
1 stop
ILM5:10 pmWilmington New Hanover County
$584
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Wilmington to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Mon 1/26

5:29 pm-1:27 pm

2 stops19h 58m

Panama City Tocumen Intl

Fri 1/30

2:27 pm-9:57 am

2 stops19h 30m

$440

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Mon 1/26

7:13 pm-1:27 pm

1 stop18h 14m

Panama City Tocumen Intl

Fri 1/30

4:50 pm-11:57 pm

1 stop7h 07m

$445

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 11/26

6:00 am-1:43 pm

1 stop7h 43m

Panama City Tocumen Intl

Wed 12/3

4:43 pm-11:59 pm

1 stop7h 16m

$476

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 11/26

6:00 am-1:43 pm

1 stop7h 43m

Panama City Tocumen Intl

Wed 12/3

4:43 pm-1:04 pm

2 stops20h 21m

$480

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

6:00 am-3:52 pm

1 stop9h 52m

Panama City Tocumen Intl

Sun 2/15

2:52 pm-11:57 am

2 stops21h 05m

$485

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Fri 1/2

5:01 am-3:54 pm

1 stop10h 53m

Panama City Tocumen Intl

Wed 1/7

4:31 pm-11:57 pm

1 stop7h 26m

$486

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Fri 1/2

5:01 am-1:53 pm

1 stop8h 52m

Panama City Tocumen Intl

Fri 1/9

4:50 pm-1:51 pm

2 stops21h 01m

$490

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Fri 1/2

7:01 pm-6:55 pm

3 stops23h 54m

Panama City Tocumen Intl

Wed 1/7

9:45 am-10:20 pm

3 stops36h 35m

$721

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 11/8

6:00 am-1:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Mon 11/10

3:37 pm-1:38 pm

1 stop22h 01m

$757

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 11/8

6:00 am-1:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sun 11/9

3:37 pm-11:15 pm

1 stop7h 38m

$984

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Wilmington to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

According to our data, Monday is the cheapest day to fly to Panama from Wilmington. The lowest ticket price found for a Monday departure recently was $312. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Wilmington to Panama for around $713.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Wilmington to Panama when you can find flight prices for as low as $321. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $550 per ticket.

Cheap Wilmington to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Wilmington to Panama

Direct flights

None
There are no direct flights from Wilmington to Panama. There are no popular flight routes from Wilmington to Panama.
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  • When did momondo last update prices for flights from Wilmington New Hanover County Airport to Panama?

    Prices for flights from Wilmington New Hanover County Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Wilmington New Hanover County Airport to Panama?

  • How old do you have to be to fly from Wilmington New Hanover County Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Wilmington New Hanover County Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Wilmington to Panama

Compare and see reviews for airlines that fly from Wilmington to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $491Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Wilmington to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Wilmington.

Can I find flights from Wilmington to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Wilmington with this policy.

How can momondo help me find flights from Wilmington to Panama?

Once all potential Wilmington to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Wilmington to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Wilmington to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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