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Cheap flights from Wilmington to Panama from $436

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Wilmington to Panama departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Wilmington to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 12:55 pm
ILM
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:59 pm
PTY
-
ILM
8h 39m1 stop
$436Delta
Tue, Apr 28 - Tue, May 5
American Airlines Logo
8:24 pm - 12:15 pm
ILM
-
PTY
16h 51m2 stops
American Airlines Logo
1:55 pm - 11:00 pm
PTY
-
ILM
8h 05m1 stop
$440American Airlines
Tue, Apr 28 - Tue, May 5
American Airlines Logo
6:00 am - 1:27 pm
ILM
-
PTY
7h 27m1 stop
American Airlines Logo
4:50 pm - 11:57 pm
PTY
-
ILM
7h 07m1 stop
$456American Airlines
Wed, Feb 4 - Mon, Feb 9
American Airlines Logo
5:19 pm - 1:27 pm
ILM
-
PTY
20h 08m2 stops
American Airlines Logo
2:27 pm - 9:26 am
PTY
-
ILM
18h 59m2 stops
$460American Airlines
Wed, Feb 4 - Mon, Feb 9
American Airlines Logo
6:00 am - 1:27 pm
ILM
-
PTY
7h 27m1 stop
American Airlines Logo
2:27 pm - 11:56 am
PTY
-
ILM
21h 29m2 stops
$480American Airlines
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
6:00 am - 1:27 pm
ILM
-
PTY
7h 27m1 stop
American Airlines Logo
2:27 pm - 11:57 pm
PTY
-
ILM
9h 30m1 stop
$496American Airlines
Sat, Jan 24 - Sat, Jan 31
American Airlines Logo
6:00 am - 1:27 pm
ILM
-
PTY
7h 27m1 stop
American Airlines Logo
2:27 pm - 9:35 am
PTY
-
ILM
19h 08m2 stops
$500American Airlines
Sat, Jan 24 - Sat, Jan 31
American Airlines Logo
5:29 pm - 3:38 pm
ILM
-
PTY
22h 09m2 stops
American Airlines Logo
4:05 pm - 11:59 pm
PTY
-
ILM
7h 54m1 stop
$505American Airlines
Sat, Jan 17 - Sun, Feb 15
American Airlines Logo
6:38 pm - 1:27 pm
ILM
-
PTY
18h 49m1 stop
American Airlines Logo
4:05 pm - 11:59 pm
PTY
-
ILM
7h 54m1 stop
$511American Airlines
Sat, Jan 17 - Sun, Feb 15
American Airlines Logo
6:38 pm - 1:27 pm
ILM
-
PTY
18h 49m1 stop
American Airlines Logo
2:50 pm - 10:32 am
PTY
-
ILM
19h 42m2 stops
$515American Airlines
Sat, Jan 17 - Sun, Feb 15

American Airlines flights from Wilmington to Panama

Our best American Airlines deals on Wilmington to Panama flight tickets
American Airlines
Apr 28
ILM8:24 pmWilmington New Hanover County
16h 51m
2 stops
PTY12:15 pmPanama City Tocumen Intl
May 5
PTY1:55 pmPanama City Tocumen Intl
8h 05m
1 stop
ILM11:00 pmWilmington New Hanover County
$440
Find similar
American Airlines
Feb 4
ILM6:00 amWilmington New Hanover County
7h 27m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 9
PTY4:50 pmPanama City Tocumen Intl
7h 07m
1 stop
ILM11:57 pmWilmington New Hanover County
$456
Find similar
American Airlines
Feb 4
ILM5:19 pmWilmington New Hanover County
20h 08m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 9
PTY2:27 pmPanama City Tocumen Intl
18h 59m
2 stops
ILM9:26 amWilmington New Hanover County
$460
Find similar

Delta flights from Wilmington to Panama

Our best Delta deals on Wilmington to Panama flight tickets
Delta
Apr 28
ILM6:00 amWilmington New Hanover County
7h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 5
PTY2:20 pmPanama City Tocumen Intl
8h 39m
1 stop
ILM11:59 pmWilmington New Hanover County
$436
Find similar
Delta
Jan 7
ILM6:00 amWilmington New Hanover County
7h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 14
PTY3:20 pmPanama City Tocumen Intl
8h 31m
1 stop
ILM11:51 pmWilmington New Hanover County
$656
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Wilmington to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 4/28

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 5/5

2:20 pm-11:59 pm

1 stop8h 39m

$436

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 4/28

8:24 pm-12:15 pm

2 stops16h 51m

Panama City Tocumen Intl

Tue 5/5

1:55 pm-11:00 pm

1 stop8h 05m

$440

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 2/4

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Mon 2/9

4:50 pm-11:57 pm

1 stop7h 07m

$456

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 2/4

5:19 pm-1:27 pm

2 stops20h 08m

Panama City Tocumen Intl

Mon 2/9

2:27 pm-9:26 am

2 stops18h 59m

$460

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 1/7

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 1/14

2:27 pm-11:56 am

2 stops21h 29m

$480

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/24

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Sat 1/31

2:27 pm-11:57 pm

1 stop9h 30m

$496

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/24

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Sat 1/31

2:27 pm-9:35 am

2 stops19h 08m

$500

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

5:29 pm-3:38 pm

2 stops22h 09m

Panama City Tocumen Intl

Sun 2/15

4:05 pm-11:59 pm

1 stop7h 54m

$505

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

6:38 pm-1:27 pm

1 stop18h 49m

Panama City Tocumen Intl

Sun 2/15

4:05 pm-11:59 pm

1 stop7h 54m

$511

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

6:38 pm-1:27 pm

1 stop18h 49m

Panama City Tocumen Intl

Sun 2/15

2:50 pm-10:32 am

2 stops19h 42m

$515

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Wilmington to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

According to our data, Monday is the cheapest day to fly to Panama from Wilmington. The lowest ticket price found for a Monday departure recently was $312. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Wilmington to Panama for around $713.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Wilmington to Panama when you can find flight prices for as low as $321. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $550 per ticket.

Cheap Wilmington to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Wilmington to Panama

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Wilmington to Panama takes 7h 55m
There are no direct flights from Wilmington to Panama. There are no popular flight routes from Wilmington to Panama.
Search flight deals

  • When did momondo last update prices for flights from Wilmington New Hanover County Airport to Panama?

    Prices for flights from Wilmington New Hanover County Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Wilmington New Hanover County Airport to Panama?

  • How old do you have to be to fly from Wilmington New Hanover County Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Wilmington New Hanover County Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Wilmington to Panama

Compare and see reviews for airlines that fly from Wilmington to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $495Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Wilmington to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Wilmington.

Can I find flights from Wilmington to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Wilmington with this policy.

How can momondo help me find flights from Wilmington to Panama?

Once all potential Wilmington to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Wilmington to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Wilmington to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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