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Cheap flights from Syracuse to Panama from $227

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to Panama departing on 3/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 7:59 pmSYR-PTY
13h 59m1 stop
Delta Logo
8:05 am - 11:33 pmPTY-SYR
15h 28m1 stop
$518Delta
Find Deal
Fri, Nov 28 - Sat, Dec 13
Delta Logo
5:30 am - 7:59 pmSYR-PTY
14h 29m2 stops
Delta Logo
8:05 am - 11:11 pmPTY-SYR
15h 06m2 stops
$522Delta
Find Deal
Fri, Nov 28 - Sat, Dec 13
United Airlines Logo
5:23 pm - 2:45 pmSYR-PTY
21h 22m2 stops
United Airlines Logo
11:55 pm - 9:54 amPTY-SYR
9h 59m1 stop
$611United Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
United Airlines Logo
10:49 am - 8:02 pmSYR-PTY
9h 13m1 stop
United Airlines Logo
11:55 pm - 9:54 amPTY-SYR
9h 59m1 stop
$695United Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
11:57 am - 8:19 pmSYR-PTY
8h 22m1 stop
Multiple Airlines Logo
2:55 am - 9:25 amPTY-SYR
30h 30m2 stops
$817Multiple Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 12
Multiple Airlines Logo
8:20 pm - 5:53 pmSYR-PTY
21h 33m1 stop
Multiple Airlines Logo
2:55 am - 7:35 pmPTY-SYR
16h 40m2 stops
$937Multiple Airlines
Find Deal
Fri, Dec 5 - Thu, Dec 11
Multiple Airlines Logo
8:20 pm - 5:53 pmSYR-PTY
21h 33m1 stop
Multiple Airlines Logo
9:40 am - 7:35 pmPTY-SYR
9h 55m1 stop
$1,322Multiple Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 12
Multiple Airlines Logo
11:57 am - 4:55 pmSYR-PTY
28h 58m3 stops
Multiple Airlines Logo
7:50 pm - 2:09 pmPTY-SYR
18h 19m2 stops
$1,955Multiple Airlines
Find Deal
Fri, Nov 28 - Sat, Dec 13

Delta flights from Syracuse to Panama

Our best Delta deals on Syracuse to Panama flight tickets
Delta
Nov 28
SYR6:00 amSyracuse Hancock Intl
13h 59m
1 stop
PTY7:59 pmPanama City Tocumen Intl
Dec 13
PTY8:05 amPanama City Tocumen Intl
15h 28m
1 stop
SYR11:33 pmSyracuse Hancock Intl
$518
Find similar
Delta
Nov 28
SYR5:30 amSyracuse Hancock Intl
14h 29m
2 stops
PTY7:59 pmPanama City Tocumen Intl
Dec 13
PTY8:05 amPanama City Tocumen Intl
15h 06m
2 stops
SYR11:11 pmSyracuse Hancock Intl
$522
Find similar

United Airlines flights from Syracuse to Panama

Our best United Airlines deals on Syracuse to Panama flight tickets
United Airlines
Oct 22
SYR6:00 amSyracuse Hancock Intl
8h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Oct 24
PTY3:30 pmPanama City Tocumen Intl
24h 17m
2 stops
SYR4:47 pmSyracuse Hancock Intl
$522
Find similar
United Airlines
Dec 4
SYR5:23 pmSyracuse Hancock Intl
21h 22m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Dec 11
PTY11:55 pmPanama City Tocumen Intl
9h 59m
1 stop
SYR9:54 amSyracuse Hancock Intl
$611
Find similar
United Airlines
Dec 4
SYR10:49 amSyracuse Hancock Intl
9h 13m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Dec 11
PTY11:55 pmPanama City Tocumen Intl
9h 59m
1 stop
SYR9:54 amSyracuse Hancock Intl
$695
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 21, 2025.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 11/28

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

Sat 12/13

8:05 am-11:33 pm

1 stop15h 28m

$518

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 11/28

5:30 am-7:59 pm

2 stops14h 29m

Panama City Tocumen Intl

Sat 12/13

8:05 am-11:11 pm

2 stops15h 06m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/4

5:23 pm-2:45 pm

2 stops21h 22m

Panama City Tocumen Intl

Thu 12/11

11:55 pm-9:54 am

1 stop9h 59m

$611

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/4

10:49 am-8:02 pm

1 stop9h 13m

Panama City Tocumen Intl

Thu 12/11

11:55 pm-9:54 am

1 stop9h 59m

$695

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 11/28

11:57 am-8:19 pm

1 stop8h 22m

Panama City Tocumen Intl

Fri 12/12

2:55 am-9:25 am

2 stops30h 30m

$817

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 12/5

8:20 pm-5:53 pm

1 stop21h 33m

Panama City Tocumen Intl

Thu 12/11

2:55 am-7:35 pm

2 stops16h 40m

$937

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 12/5

8:20 pm-5:53 pm

1 stop21h 33m

Panama City Tocumen Intl

Fri 12/12

9:40 am-7:35 pm

1 stop9h 55m

$1,322

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 11/28

11:57 am-4:55 pm

3 stops28h 58m

Panama City Tocumen Intl

Sat 12/13

7:50 pm-2:09 pm

2 stops18h 19m

$1,955

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 3/14

7:59 pm-1:45 pm

2 stops18h 46m

$227

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 3/14

6:00 pm-12:10 pm

2 stops19h 10m

$283

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Syracuse to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Syracuse, with most prices found around $507. If you don’t want to visit Panama in November, then you should wait until June to fly from Syracuse, when ticket prices are also cheap, with an average price of $524.

What is the cheapest day to depart on your flight to Panama?

According to our data, Monday is the cheapest day to fly to Panama from Syracuse. The lowest ticket price found for a Monday departure recently was $475. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Syracuse to Panama for around $739.

What is the cheapest time of day to depart on your flight to Panama?

In the morning is the cheapest time of day to fly from Syracuse to Panama when you can find flight prices for as low as $585. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $890 per ticket.

Cheap Syracuse to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Panama

Direct flights

None
There are no direct flights from Syracuse to Panama. There are no popular flight routes from Syracuse to Panama.
Search flight deals

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Panama?

    Prices for flights from Syracuse Hancock Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Panama?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Syracuse Hancock Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Syracuse to Panama

Compare and see reviews for airlines that fly from Syracuse to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $490Free CancellationRating
7.4
8,991 reviews
Search United Airlines flights
DeltaPriceFrom $491Free CancellationRating
7.9
7,978 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to Panama for you.

Can I find flights from Syracuse to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Syracuse to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Syracuse to Panama?

Once all potential Syracuse to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Syracuse to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Syracuse and alert you when they change.

An easier way to manage your Panama trip

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